Pyrimethamine (Daraprim)

Zvemukati

• Mutengo
• Zviratidzo
• Kushandisa sei
• Zvimwe zvinokanganisa
• Contraindications

Daraprim mushonga unorwisa marariya uyo unoshandisa pyrimethamine sechinhu chinoshanda, kugona kudzivisa kugadzirwa kwemakemikari neprotozoan inokonzeresa nemarariya, nekudaro ichirapa chirwere.

Daraprim inogona kutengwa kubva kune akajairwa mafammesi ane mushonga muchimiro chemabhokisi ane mapiritsi zana e25 mg.

Mutengo

Mutengo weDaraprim ungangoita 7 reais, zvisinei hazvo huwandu hungasiyana zvichienderana nenzvimbo inotengwa mushonga.

Zviratidzo

Daraprim inoratidzirwa yekudzivirira uye kurapwa kwemalaria, pamwe nemimwe mishonga. Uye zvakare, Daraprim inogona zvakare kushandiswa kurapa Toxoplasmosis, sekureva kwechiremba.

Kushandisa sei

Mashandisiro ekushandisa Daraprim anosiyana zvichienderana nechinangwa chekurapa uye zera remurwere, iine general mirayiridzo inosanganisira:

Kudzivirira marariya

• Vakuru nevana pamusoro pemakore gumi: 1 piritsi pavhiki;
• Vana vane makore mashanu kusvika pagumi emakore: ½ piritsi pavhiki;
• Vana vari pasi pe5: ¼ piritsi pavhiki.

Kurapa kweMalaria

• Vakuru nevana vanopfuura makore gumi nemana: Mahwendefa maviri kusvika kumatatu pamwe ne1000 mg kusvika ku1500 mg yesulfadiazine mune imwe dose;
• Vana vane makore 9 kusvika 14 emakore: Mahwendefa maviri pamwe ne1000 mg ye sulfadiazine mune imwe chete dosi;
• Vana vane makore mana kusvika pamasere emakore: 1 piritsi pamwe ne1000 mg ye sulfadiazine mune imwe dosi
• Vana vari pasi pemakore mana: ½ piritsi pamwe ne1000 mg ye sulfadiazine mune imwe dose.

Zvimwe zvinokanganisa

Iwo makuru mhedzisiro mhedzisiro yeDaraprim anosanganisira kusagadzikana kweganda, kurova maronda, kusvotwa, kurwadza, manyoka, kushaya kudya, ropa mumurini uye shanduko mukuyedzwa kweropa.

Contraindications

Daraprim inopesana nevarwere vane sekondari megaloblastic anemia nekuda kwekushomeka kwefolate kana hypersensitivity kune pyrimethamine kana chimwe chezvinhu zvemufomula.