Serotonin syndrome: chii, zviratidzo, zvinokonzera uye kurapwa

Zvemukati

• Ndezvipi zviratidzo
• Zvinogona kukonzerwa
• Mishonga inowedzera serotonin mumuviri
• Kurapwa kunoitwa sei

Serotonin syndrome inosanganisira kuwedzera kwebasa re serotonin mukati mehurongwa hwekutyaira, hunokonzerwa nekushandisa zvisina kukodzera kwemimwe mishonga, iyo inogona kukanganisa huropi, mhasuru uye nhengo dzemuviri, izvo zvinogona kutungamira kurufu.

Serotonin inonzi neurotransmitter inoshanda pauropi, yakakosha pakushanda kwakanaka kweiyo muviri, nekuti inodzora manzwiro, kurara, kudya, kurova kwemoyo, tembiricha yemuviri uye kugona kwekuziva. Zvisinei, kuwanda kweserotonin kunogona kudzikamisa mashandiro emuviri uye kunotungamira mukuonekwa kwezviratidzo zvakakomba. Ona mamwe mabasa eserotonin.

Kurapa kweserotonin syndrome kunofanirwa kuitwa kuchipatara, nekukurumidza sezvinobvira, kuburikidza nekutungamirwa kweserum mutsinga, kumiswa kwemushonga wakakonzera dambudziko uye kushandiswa kwemishonga kubvisa zviratidzo.

Ndezvipi zviratidzo

Kushushikana, kutsamwa, kuputika kwemhasuru, kuvhiringidzika uye kuona zvisipo, kudedera uye kutonhora, kusvotwa uye manyoka, kuwedzerwa kweropa uye kurova kwemoyo, kuwanda kwekufungisisa, vadzidzi vakawedzera, ndizvo zviratidzo zvinowanzoonekwa.

Mune zviitiko zvakakomba uye kana ikasarapwa nekukurumidza, serotonin syndrome inogona kupa zviratidzo zvakanyanya, sekushomeka kwemoyo zvisina kujairika, kurasikirwa kwekuziva, kufenda, kufenda uye kufa.

Zvinogona kukonzerwa

Serotonin syndrome inokonzerwa nekushandisa zvisina kukodzera kwemishonga inowedzera huwandu hweserotonin mumuviri. Nekudaro, kuwedzera kuyerwa kwemishonga inowedzera serotonin, kusanganiswa kwemishonga iyi nevamwe inosimudzira kuita kwavo, kana kushandiswa kwemishonga iyi panguva imwe chete nemishonga, kunogona kukonzera kuitika kwechirwere ichi.

Mishonga inowedzera serotonin mumuviri

Mimwe yemishonga inowedzera serotonin mumuviri ndeiyi:

• Zvinodzvinyirira, senge imipramine, clomipramine, amitriptyline, nortriptyline, fluoxetine, paroxetine, citalopram, sertraline, fluvoxamine, venlafaxine, duloxetine, nefazodone, trazodone, bupropion, mirtazapine, tranylcypemine uye moclobine.
• Migraine Remedies iro boka rematripani, senge zolmitriptan, naratriptan kana sumatriptan, semuenzaniso;
• Kukosora Mishonga iyo ine dextromethorphan, chinova chinhu chinoshanda pane yepakati sisitimu yekudzivirira kukosora;
• Opioid yakashandiswa kurapa kurwadziwa, senge codeine, morphine, fentanyl, meperidine uye tramadol, semuenzaniso;
• Mishonga yekurutsa uye kurutsa, senge metoclopramide uye ondansetron;
• Anticonvulsants, senge sodium valproate uye carbamazepine;
• Mishonga inorwisa mabhakitiriya, antifungals uye antivirals, senge erythromycin, ciprofloxacin, fluconazole uye ritonavir;
• Zvinodhaka zvisiri pamutemo, senge cocaine, amphetamines, LSD uye ecstasy.

Uye zvakare, zvimwe zvinowedzerwa zvepanyama, zvakadai setryptophan, St.John's wort (St. John's wort) uye ginseng, kana ichibatanidzwa nemishonga yekudzvinyirira, inogona zvakare kukonzera serotonin syndrome.

Kurapwa kunoitwa sei

Kurapa kweserotonin syndrome kunoenderana nekuomarara kwezviratidzo. Muzviitiko zvine mwero kusvika zvakakomba, zvinofanirwa kuitwa nekukurumidza sezvazvinogona, muchipatara, uko munhu anotariswa uye anogona kugamuchira serum mutsinga nemishonga yekurapa zviratidzo, zvakaita sefivha, kushungurudzika uye mhasuru, semuenzaniso. Mune zvimwe zviitiko zvakakomba, zvinogona kuve zvakakosha kutora mishonga inovhara kuita kweserotonin.

Uye zvakare, iyo mishonga inotorwa nemunhu inofanirwa kuongororwa uye kugadziridzwa nachiremba, pamwe nemitero yakatemwa.