Zytiga (abiraterone): chii icho, chii chaicho uye mashandisiro
Zvemukati
Zytiga mushonga unoshandiswa mukurapa kenza yeprostate iyo ine abiraterone acetate sechinhu chayo chinoshanda. Abiraterone inodzivirira chinhu chinodikanwa mukugadzirwa kwehomoni inodzora hunhu hwechirume, asi izvo zvinoenderanawo nekuwedzera kwegomarara. Nekudaro, uyu mushonga unodzivirira kufambira mberi kwethumba muprostate, ichiwedzera hupenyu hwehupenyu.
Kunyangwe abytaterone yaZytiga inokonzeresa kuti maadrenal gland abudise huwandu hwakawanda hwecorticosteroids, zvakajairika kuti chiremba akurudzirewo zvinodhaka zvecorticosteroid pamwechete, kubatsira kudzikisa kuzvimba kweprostate uye kugadzirisa zviratidzo, sekushushikana kuita weti kana kunzwa kwekuzara kwedundira. muenzaniso.
Mushonga uyu unowanikwa mumahwendefa e250 mg uye iwo wepakati mutengo uri gumi kusvika gumi nemashanu ezviuru reais pasuru, asi iri zvakare inowanikwa mune iyo SUS zvinodhaka runyorwa.
Chii ichochi
Zytiga inoratidzirwa pakurapa kenza yeprostate muvarume vakuru kana gomarara rapararira nemuviri. Inogona zvakare kushandiswa mune varume vasina kuvandudza chirwere chavo mushure mekukandwa kudzvinyirira kugadzirwa kwehomoni dzebonde kana mushure memakemikari ne docetaxel.
Kushandisa sei
Mashandisiro eZytiga anosanganisira kutora mapiritsi 4 250 mg mune imwe chete dose, angangoita maawa maviri mushure mekudya. Hapana chikafu chinofanirwa kudyiwa kweinenge 1 awa mushure mekushandisa. Usapfuure yakanyanya zuva nezuva dhizaini ye1000 mg.
Zytiga inowanzo kutorwa pamwe chete ne5 kana 10 mg ye prednisone kana prednisolone, kaviri pazuva, sekurairwa nachiremba.
Zvinogona kuitika mhedzisiro
Iko kushandiswa kwemushonga uyu kunogona kutungamira mukuonekwa kwemimwe mhedzisiro, iyo yakajairika pane iyo inogona kusanganisira:
- Kuzvimba kwemakumbo netsoka;
- Urinary chirwere;
- Kuwedzera kweropa;
- Kuwedzera kwehuwandu hwemafuta muropa;
- Yakawedzera kurova kwemoyo;
- Kurwadziwa pachifuva;
- Zvinetso zvemwoyo;
- Manyoka;
- Mavara matsvuku paganda.
Panogona zvakare kuve nekudzikiswa kwemazinga e potassium mumuviri, zvichitungamira pakuonekwa kwekushomeka kwemhasuru, cramp uye moyo palpitations.
Kazhinji, uyu mushonga unoshandiswa pamwe nekutarisisa kwechiremba kana nyanzvi yehutano, senge mukoti, uyo anozotarisa pakuonekwa kweiyi yeiyi mhedzisiro, kutanga kurapwa kwakakodzera, kana zvichidikanwa.
Ndiani asingafanire kutora
Zytiga inopesana nevanhu vane hypersensitive kune abiraterone kana chero chinhu chemufomula, pamwe nevarwere vane chiropa chakakundikana. Iyo haifanire kupihwa kune vakadzi vane nhumbu kana panguva yekuyamwisa.