Whipple chirwere

Whipple chirwere chinhu chisingawanzoitika chinonyanya kukanganisa hutumbu hudiki. Izvi zvinodzivirira ura hudiki kubva pakubvumira zvinovaka muviri kuti zvipfuure mune imwe muviri wese. Izvi zvinonzi malabsorption.

Whipple chirwere chinokonzerwa nehutachiona nechimiro chehutachiona hunodaidzwa Tropheryma whipplei. Dambudziko iri rinonyanya kubata varume vachena vepakati-zera.

Whipple chirwere ishoma kwazvo. Njodzi zvinhu hazvizivikanwe.

Zviratidzo zvinowanzotanga zvishoma nezvishoma. Kurwadziwa pamwe chete ndicho chiratidzo chinowanzozivikanwa. Zviratidzo zvehutachiona (GI) hutachiona zvinowanzoitika makore akati wandei gare gare. Zvimwe zviratidzo zvinogona kusanganisira:

• Marwadzo emudumbu
• Manyoka
• Kupindwa nechando
• Kusviba kweganda munzvimbo dzakajeka-dzakajeka dzemuviri
  
• Joint kurwadziwa mumakumbo, mabvi, magokora, zvigunwe, kana dzimwe nzvimbo
• Kurasikirwa kwendangariro
• Kuchinja kwepfungwa
• Kuonda

Anopa hutano anoita bvunzo dzepanyama. Izvi zvinogona kuratidza:

• Yakawedzera lymph gland
• Moyo kugunun'una
• Kuzvimba mumatumbu emuviri (edema)

Kuyedza kuongorora chirwere cheWhipple kunogona kusanganisira:

• Yakazara kuverenga ropa (CBC)
• Polymerase chain reaction (PCR) bvunzo kutarisa mabhakitiriya anokonzera chirwere
• Diki ura bhiopsy
• Kumusoro kweGI endoscopy (kutarisa ura neyakagadziriswa, yakavhenekerwa chubhu munzira inonzi enteroscopy)

Chirwere ichi chinogona zvakare kuchinja mhedzisiro yemiedzo inotevera:

• Albumin mazinga muropa
• Unabsorbed mafuta muzvigaro (fecal fat)
• Kugunzva kwemukati wemhando yeshuga (d-xylose kunwa)

Vanhu vane chirwere cheWhipple vanofanirwa kutora marefu-refu maantibioti kurapa chero hutachiona hwehuropi uye yepakati tsinga system. Mishonga inorwisa mabhakitiriya inonzi ceftriaxone inopihwa kuburikidza netsinga (IV). Inoteverwa neimwe antibiotic (senge trimethoprim-sulfamethoxazole) inotorwa nemuromo kwegore rimwe chete.

Kana zviratidzo zvikadzoka panguva yekushandisa mishonga inorwisa mabhakitiriya, mishonga inogona kuchinjwa.

Wako mupi anofanira kunyatsoteedzera kufambira mberi kwako. Zviratidzo zvechirwere zvinogona kudzoka kana wapedza kurapwa. Vanhu vanosara vasina kudya zvinovaka muviri vanozofanira zvakare kutora zvekuwedzera zvekudya.

Kana ikasarapwa, mamiriro acho anowanzo kuuraya. Kurapa kunoderedza zviratidzo uye kunogona kuporesa chirwere.

Zvinetso zvinogona kusanganisira:

• Kukuvara kwehuropi
• Kukuvara kwevhavha yemoyo (kubva endocarditis)
• Kushomeka kwehutano
• Zviratidzo zvinodzoka (izvo zvinogona kunge zviri nekuda kwekurwisa zvinodhaka)
• Kuonda

Fonera mupiki wako kana iwe uine:

• Joint kurwadziwa kusingaendi
• Marwadzo emudumbu
• Manyoka

Kana iwe uri kurapwa chirwere cheWhipple, fonera mupi wako kana:

• Zviratidzo zvinowedzera kuwedzera kana kusavandudza
• Zviratidzo zvinotangazve
• Zviratidzo zvitsva zvinokura

Utumbo lipodystrophy

Maiwald M, von Herbay A, Relman DA. Whipple chirwere. Muna: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger uye Fordtran's Gastrointestinal uye Chirwere Chiropa. 11th ed. Philadelphia, PA: Elsevier; 2021: chits. 109.

Marth T, Schneider T. Whipple chirwere. Mune: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, uye Bennett's Maitiro uye Maitiro Ezvirwere zvinotapukira. 9th ed. Philadelphia, PA: Elsevier; 2020: chap 210.

West SG. Zvirwere zvehurongwa umo arthritis chinhu. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chitsipa 259.