Pseudomembranous colitis

Pseudomembranous colitis inoreva kuzvimba kana kuzvimba kwemukati ura (colon) nekuda kwekukura kwe Clostridioides difficile (C difficile) mabhakitiriya.

Utachiona uhu ndihwo hwunowanzokonzera manyoka mushure mekushandisa mishonga inorwisa mabhakitiriya.

Iyo C difficile mabhakitiriya anowanzogara mumatumbo. Nekudaro, akawandisa mabhakitiriya aya anogona kukura kana iwe ukatora maantibioti Iyo bhakitiriya inopa huturu hwakasimba hunokonzera kuzvimba uye kubuda kweropa mumutsara wekoloni.

Chero mishonga inorwisa mabhakitiriya inogona kukonzera mamiriro aya. Iyo mishonga inokonzeresa dambudziko nguva zhinji ndeye ampicillin, clindamycin, fluoroquinolones, uye cephalosporins.

Vanopa hutano muchipatara vanogona kupfuudza hutachiona uhwu kubva kune mumwe munhu kuenda kune mumwe.

Pseudomembranous colitis haina kujairika muvana, uye zvisingawanzoitika muvacheche. Inowanzoonekwa muvanhu vari muchipatara. Zvisinei, zviri kuwedzera kuva vanhu vanotora mishonga inorwisa mabhakitiriya uye vasiri muchipatara.

Njodzi zvinhu zvinosanganisira:

• Kukwegura
• Kushandisa mishonga inorwisa mabhakitiriya
• Kushandiswa kwemishonga inoderedza immune system (senge chemotherapy mishonga)
• Kuvhiya kwazvino
• Nhoroondo yepseudomembranous colitis
• Nhoroondo ye ulcerative colitis uye chirwere cheCrohn

Zviratidzo zvinosanganisira:

• Abdominal cramp (nyoro kusvika kune yakaoma)
• Ropa zvigaro
• Kupindwa nechando
• Kurudzira kuita hutumbu
• Manyoka emvura (kazhinji kashanu kusvika kagumi pazuva)

Iyi bvunzo inotevera inogona kuitwa:

• Colonoscopy kana inoshanduka sigmoidoscopy
• Immunoassay yeC inoparadzaniswa chepfu muchigaro
• Nyowani zvituru bvunzo senge PCR

Iyo inorwisa mabhakitiriya kana mumwe mushonga unokonzera mamiriro acho unofanirwa kumiswa. Metronidazole, vancomycin, kana fidaxomicin inowanzo shandiswa kurapa dambudziko, asi mimwe mishonga inogona kushandiswa.

Electrolyte mhinduro kana zvinwiwa zvinopihwa kuburikidza nemutsinga zvinogona kudiwa kurapa kupera mvura mumuviri nekuda kwemanyoka. Muzviitiko zvisingawanzoitika, kuvhiya kunodiwa kurapa hutachiona hunowedzera kana kusapindura mishonga inorwisa mabhakitiriya.

Yenguva refu maantibhakitiriya anogona kudikanwa kana iyo C difficile hutachiona hunodzoka. Mushonga mutsva unonzi fecal microbiota transplant ("stool transplant") wakashandawo kuzvirwere zvinodzoka.

Wako mupi anogona zvakare kukurudzira kuti utore mapurobioti kana hutachiona hwadzoka.

Iko kutaridzika kwakanaka mune dzakawanda kesi, kana pasina zvinetswa. Nekudaro, anosvika 1 mu5 hutachiona anogona kudzoka uye achida kurapwa kwakawanda.

Zvinetso zvinogona kusanganisira:

• Kupererwa nemvura nemvura ine kusaenzana kwemagetsi
• Kukanganiswa kwe (hole kuburikidza) iyo colon
• Megokoni ine chepfu
• Rufu

Fonera mupiki wako kana iwe uine zvinotevera zviratidzo:

• Chero zvigaro zveropa (kunyanya mushure mekutora mishonga inorwisa mabhakitiriya)
• Zvikamu zvishanu kana kupfuura zvemanyoka pazuva kwemazuva anopfuura rimwe kana maviri
• Kutambudzika kwakanyanya kwepamuviri
• Zviratidzo zvekushaya mvura mumuviri

Vanhu vakamboita pseudomembranous colitis vanofanirwa kutaurira vanopa rubatsiro vasati vatora maantibioti zvakare. Zvakakoshawo kushambidza maoko zvakanaka kudzivirira kutapurira utachiona uhwu kune vamwe vanhu. Doro sanitizers haigare ichishanda pane C difficile.

Inorwisa mabhakitiriya-inosanganiswa colitis; Colitis - pseudomembranous; Necrotizing colitis; C difficile - pseudomembranous

• Kugaya chirongwa
• Digestive system nhengo

Gerding DN, Johnson S. Clostridial hutachiona. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chitsiko 280.

Gerding DN, Mudiki VB. Donskey CJ. Clostridiode difficile (kare Clostridium difficle) hutachiona. Mune: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, uye Bennett's Maitiro uye Maitiro Ezvirwere zvinotapukira. 9th ed. Philadelphia, PA: Elsevier; 2020: chitsama 243.

Kelly CP, Khanna S. Antibiotic-inosangana manyoka uye clostridioides difficile hutachiona. Muna: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger uye Fordtran's Gastrointestinal uye Chirwere Chiropa. 11th ed. Philadelphia, PA: Elsevier; 2021: chits. 112.

McDonald LC, Gerding DN, Johnson S, et al. Clinical tsika nhungamiro ye clostridium difficile Kutapukirwa muvakuru nevana: 2017 inogadzirisirwa neInfectious Diseases Society yeAmerica (IDSA) uye Sosaiti yehutano Hutano Epidemiology yeAmerica (SHEA). Clin Infect Dis. 2018; 66 (7): 987-994. PMID: 29562266 pubmed.ncbi.nlm.nih.gov/29562266/.