Kenza yehutachiona - medullary carcinoma

Medullary carcinoma yehutachiona ikenza yeglandi gland inotangira mumasero anoburitsa hormone inonzi calcitonin. Masero aya anonzi "C" masero. Iyo yegland gland inowanikwa mukati mepamberi pemutsipa wezasi.

Chikonzero che medullary carcinoma yehutachiona (MTC) hachizivikanwe. MTC isingawanzoitika. Inogona kuitika kuvana nevakuru.

Kusiyana nedzimwe mhando dzekenza yehutachiona, MTC haigone kukonzerwa nemwaranzi kurapwa kumutsipa wakapihwa kurapa mamwe kanzira panguva yehucheche.

Kune mafomu maviri eMTC:

• Sporadic MTC, iyo isingamhanye mumhuri. Mazhinji maMTCs anowanzoitika. Iyi fomu inonyanya kubata vakuru vakura.
• Hereditary MTC, iyo inomhanya mumhuri.

Iwe une njodzi yakawedzera yerudzi urwu rwecancer kana uine:

• Nhoroondo yemhuri yeMTC
• Nhoroondo yemhuri yeakawanda endocrine neoplasia (MEN)
• Nhoroondo yekutanga pheochromocytoma, mucosal neuromas, hyperparathyroidism kana pancreatic endocrine tumors.

Dzimwe mhando dzegomarara rekenza dzinosanganisira:

• Anaplastic carcinoma yehutachiona
• Follicular bundu utachiona
• Papillary carcinoma yehutachiona
• Utachiona lymphoma

MTC inowanzotanga sebundu diki (nodule) mune yegland gland. Ikoko zvakare kunogona kuve ne lymph node kuzvimba mumutsipa. Nekuda kweizvozvo, zviratidzo zvinogona kusanganisira:

• Kuzvimba kwemutsipa
• Kuchema
• Matambudziko ekufema nekuda kwekudzikisira kwemhepo
• Kukosora
• Kosora neropa
• Dhairrhea nekuda kweiyo yakakwira calcitonin level

Anokuchengetedza hutano achaita bvunzo dzepanyama uye obvunza nezve ako zviratidzo uye nhoroondo yekurapa.

Miedzo inogona kushandiswa kuongorora MTC inosanganisira:

• Calcitonin kuongororwa kweropa
• CEA kuongorora ropa
• Kuongorora genetic
• Utachiona bhiopsy
• Ultrasound yehutachiona uye lymph nodes yemutsipa
• PET scan

Vanhu vane MTC vanofanirwa kuongororwa kuti vaone mamwe mamota, kunyanya pheochromocytoma uye maperembudzi matumbo uye maperembudzi mapundu.

Kurapa kunosanganisira kuvhiyiwa kubvisa chirwere chetachiona uye ma lymph nodes akakomberedza. Nekuti iri ibundu risingazivikanwe, kuvhiyiwa kunofanirwa kuitwa nachiremba anoziva chirwere chegomarara ichi uye ane ruzivo rwekuvhiya kunodiwa.

Kuenderera mberi kurapwa kunobva pane yako calcitonin mazinga. Kukwira kwemazinga ecalcitonin zvakare kunogona kuratidza kukura kutsva kwekenza.

• Chemotherapy uye radiation hazvishande zvakanyanya kune rudzi urwu rwegomarara.
• Radiation inoshandiswa mune vamwe vanhu mushure mekuvhiyiwa.
• Marapirwo matsva anotarisirwa anogona kudzora bundu kukura zvakare. Wako mupi anogona kukuudza zvakawanda nezve izvi, kana zvichidikanwa.

Pedyo nehama dzevanhu vanoonekwa vane mafomu enhaka eMTC vari panjodzi yakakura yekenza iyi uye vanofanirwa kukurukura nevanopa.

Unogona kudzikisira kushushikana kwehurwere nekujoinha boka rekutsigira gomarara. Kugovana nevamwe vane zvakajairika zviitiko uye matambudziko zvinogona kukubatsira kuti usazonzwa kusurukirwa.

Vanhu vazhinji vane MTC vanorarama makore mashanu mushure mekuongororwa, zvichienderana nedanho rekenza. Iyo makore gumi-ekupona mwero ndeye 65%.

Zvinetso zvinogona kusanganisira:

• Kenza inopararira ichienda kune dzimwe nzvimbo dzomuviri
• Zvirwere zveparathyroid zvinobviswa netsaona panguva yekuvhiyiwa

Fonera mupiki wako kana iwe uine zviratidzo zveMTC.

Kudzivirira kunogona kusakwanisika. Asi, nekuziva njodzi yako, kunyanya yako nhoroondo yemhuri, inogona kubvumidza kutanga kuongororwa uye kurapwa. Kune vanhu vane yakasimba kwazvo nhoroondo yemhuri yeMTC, iyo sarudzo yekubvisa iyo gland gland inogona kukurudzirwa. Iwe unofanirwa kunyatso kurukura nezve iyi sarudzo nachiremba anonyatsoziva chirwere ichi.

Utachiona - medullary carcinoma; Kenza - thyroid (medullary carcinoma); MTC; Utachiona nodule - medullary

• Kenza yeTiroid - CT scan
• Gland yeganda

Jonklass J, Cooper DS. Utachiona. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chitsiko 213.

National Cancer Institute webhusaiti. Kurapa kenza yehutachiona (mukuru) (PDQ) - hutano nyanzvi vhezheni. www.cancer.gov/types/thyroid/hp/thyroid-treatment-pdq. Yakagadziridzwa Ndira 30, 2020. Yakasvika paKurume 6, 2020.

Smith PW, Hanks LR, Salomone LJ, Hanks JB. Utachiona. Mu: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Chinyorwa Chekuvhiya. 20th ed. Philadelphia, PA: Elsevier Saunders; 2017: chitsuwa 36.

Viola D, Elisei R. manejimendi yekenza medulura kenza. Endocrinol Metab Kliniki North Am. 2019; 48 (1): 285-301. PMID: 30717909 pubmed.ncbi.nlm.nih.gov/30717909/.

Wells SA Jr, Asa SL, Dralle H. Revised American Thyroid Association nhungamiro yevatungamiriri ve medullary thyroid carcinoma. Utachiona. 2015; 25 (6): 567-610. PMID: 25810047 pubmed.ncbi.nlm.nih.gov/25810047/.