Klinefelter chirwere

Klinefelter syndrome chirwere chinowanikwa muvanhurume kana vaine imwe X chromosome.

Vanhu vazhinji vane ma chromosomes makumi mana nematanhatu. MaChromosomes ane ako ese majini uye DNA, zvivakwa zvemuviri. Iwo maviri echromosomes ebonde (X uye Y) anoona kana iwe ukave mukomana kana musikana. Vasikana vanowanzove ne2 X chromosomes. Vakomana kazhinji vane 1 X uye 1 Y chromosome.

Klinefelter syndrome inoguma kana mukomana achinge azvarwa aine kanenge ka1 X kromosome. Izvi zvakanyorwa saXXY.

Klinefelter syndrome inoitika mune anenge 1 pa500 kusvika chiuru chevana vacheche. Vakadzi vanoita nhumbu mushure memakore makumi matatu nemashanu vane mukana wakanyanya wekuve nemukomana ane chirwere ichi kupfuura vakadzi vadiki.

Kushaya mbereko ndicho chiratidzo chinowanzozivikanwa cheKlinefelter syndrome.

Zviratidzo zvinogona kusanganisira chero zvinotevera:

• Kuenzana kwemuviri zvakaenzana (makumbo marefu, trunk pfupi, fudzi rakaenzana nehukuru hwehudyu)
• Mazamu akakura zvisina kujairika (gynecomastia)
• Kushaya mbereko
• Zvinetso zvepabonde
• Chishoma pane zvakajairwa huwandu hwepabic, muhapwa, uye bvudzi rechiso
• Matete madiki, akasimba
• Kureba kureba
• Kukura kwepenhengo diki
  
  

Klinefelter syndrome inogona kutanga yaonekwa kana murume auya kumubatsiri wezvehutano nekuda kwekushaya mbereko. Iyi bvunzo inotevera inogona kuitwa:

• Karyotyping (inoongorora ma chromosomes)
• Urume kuverenga

Kuongororwa kweropa kuchaitwa kuongorora huwandu hwehomoni, kusanganisira:

• Estradiol, rudzi rweestrogen
• Follicle inosimudzira mahormone
• Luteinizing mahormone
• Testosterone

Testosterone therapy inogona kunyorwa. Izvi zvinogona kubatsira:

• Kukura muviri bvudzi
• Ndiwedzere chitarisiko tsandanyama
• Kuvandudza kutarisisa
• Kuvandudza mafungiro uye kuzviremekedza
• Wedzera simba uye bonde drive
• Wedzera simba

Varume vazhinji vane chirwere ichi havakwanise kutora mukadzi nhumbu. Nyanzvi yekushaya mbereko inogona kukwanisa kubatsira. Kuona chiremba anonzi endocrinologist kunogona zvakare kubatsira.

Aya masosi anogona kupa rumwe ruzivo nezve Klinefelter syndrome:

• Sangano reX uye Y Chromosome Misiyano - genetic.org
• National Raibhurari yeMishonga, Genetics Kumba Referensi - medlineplus.gov/klinefelterssyndrome.html

Mazino akawedzera ane kutetepa kwepasi akajairika muKlinefelter syndrome. Izvi zvinonzi taurodontism. Izvi zvinogona kuonekwa pamazino x-ray.

Klinefelter syndrome inowedzerawo njodzi ye:

• Kucherekedza kushomeka kwehutano kusagadzikana (ADHD)
• Autoimmune kusagadzikana, senge lupus, rheumatoid arthritis, uye Sjögren syndrome
• Gomarara repazamu muvarume
• Kushungurudzika
• Kuremara pakudzidza, kusanganisira dyslexia, iyo inokanganisa kuverenga
• Rudzi rusina kujairika bundu rinonzi extragonadal germ cell tumarara
• Chirwere chemapapu
• Osteoporosis
• Varicose tsinga

Bata mupi wako kana mwanakomana wako asingakure zvechipiri zvepabonde panguva yekuyaruka. Izvi zvinosanganisira kukura kwebvudzi kumeso uye kudzika kwezwi.

Anopa chipangamazano anogona kupa ruzivo nezve mamiriro aya uye otungamira iwe kunotsigira mapoka ari munharaunda mako.

47 XYY chirwere; XXY chirwere; XXY trisomy; 47, XXY / 46, XY; Mosaic syndrome; Poly-X Klinefelter chirwere

Allan CA, McLachlan RI. Androgen kushomeka kusagadzikana. Muna: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Vakuru uye Chiremba. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 139.

Matsumoto AM, Anawalt BD, Matambudziko eTestamente. Mune: Melmed S, Auchus, RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Chinyorwa cheEndocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020: chitsiko 19.

Nussbaum RL, McInnes RR, Willard HF. Iyo chromosomal uye genomic hwaro hwechirwere: kusagadzikana kwema autosomes uye echromosomes ebonde. Mune: Nussbaum RL, McInnes RR, Willard HF, eds. Thompson & Thompson Genetics muMushonga. 8th ed. Philadelphia, PA: Elsevier; 2016: chits.