Psoriatic arthritis

Psoriatic arthritis idambudziko rekubatana (arthritis) iyo inowanzoitika nemamiriro eganda anonzi psoriasis.

Psoriasis idambudziko rakajairika reganda rinokonzeresa zvigamba zvitsvuku paganda. Icho chinoramba chichienderera (chisingaperi) chinogumbura mamiriro. Psoriatic arthritis inoitika mune angangoita 7% kusvika 42% yevanhu vane psoriasis. Chipikiri psoriasis chakabatana ne psoriatic arthritis.

Muzviitiko zvakawanda, psoriasis inouya pamberi peArthritis. Mune vanhu vashoma, iyo arthritis inouya pamberi pechirwere cheganda. Nekudaro, kuve neakasimba, akapararira-akapararira psoriasis inoita kunge inowedzera mukana wekuwana psoriatic arthritis.

Chikonzero che psoriatic arthritis hachizivikanwe. Majini, immune system, uye zvakatipoteredza zvinhu zvinogona kutora chinzvimbo. Zvichida kuti ganda uye pamwe chete zvirwere zvinogona kuve nezvikonzero zvakafanana. Zvisinei, zvingasaitika pamwe chete.

Iyo arthritis inogona kuve yakapfava uye inosanganisira mashoma chete majoini. Iwo majoini ari panoperera zvigunwe kana zvigunwe zvinogona kuve zvakanyanya kukanganiswa. Psoriatic arthritis kazhinji haina kuenzana ichikonzera arthritis chete kudivi rimwe remuviri.

Mune vamwe vanhu, chirwere ichi chingave chakakomba uye chinokanganisa majoini mazhinji, kusanganisira musana. Zviratidzo mumuzongoza zvinosanganisira kuomarara uye kurwadziwa. Izvo zvinowanzoitika mumutsara wezasi uye sacrum.

Vamwe vanhu vane psoriatic arthritis vanogona kuve nekuputika kwemaziso.

Kazhinji yenguva, vanhu vane psoriatic arthritis vane ganda uye nzara shanduko ye psoriasis. Kazhinji, ganda rinowedzera kuwedzera panguva imwe chete neArthritis.

Tendon inogona kupiswa ne psoriatic arthritis. Mienzaniso inosanganisira iyo Achilles tendon, iyo plantar fascia, uye tendon sheath iri muruoko.

Munguva yekuongorora kwepanyama, mupi wezvehutano anotsvaga:

• Joint kuzvimba
• Makanda eganda (psoriasis) uye kurovera muzvipikiri
• Unyoro
• Kuzvimba mumaziso

Yakabatana x-ray inogona kuitwa.

Iko hakuna chaiwo kuongororwa kweropa kwe psoriatic arthritis kana ye psoriasis. Kuyedza kutonga kunze mamwe marudzi eArthritis anogona kuitwa:

• Rheumatoid chinhu
• Anti-CCP antibodies

Iye mupi anogona kuyedza geni inonzi HLA-B27 Vanhu vane kubatanidzwa kwemusana vanowanzove neHLA-B27.

Wako mupi anogona kupa asiri -steroidal anti-anogumbura zvinodhaka (NSAIDs) kudzikisira kurwadziwa uye kuzvimba kwemajoini.

Arthritis isingavandudzike neNSAID inoda kurapwa nemishonga inonzi chirwere-kugadzirisa antirheumatic zvinodhaka (DMARDs). Izvi zvinosanganisira:

• Methotrexate
• Leflunomide
• Sulfasalazine

Apremilast mumwe mushonga unoshandiswa pakurapa psoriatic arthritis.

Mishonga mitsva yebiologic inoshanda kune inofambira mberi psoriatic arthritis iyo isingadzorwe nemaDMARD. Iyi mishonga inovhara puroteni inonzi tumor necrosis factor (TNF). Ivo anowanzo kuve anobatsira kune ese ari maviri chirwere cheganda uye akabatana chirwere che psoriatic arthritis. Iyi mishonga inopihwa jekiseni.

Mimwe mishonga mitsva yebiologic inowanikwa kurapa psoriatic arthritis iri kufambira mberi kunyangwe nekushandisa maDMARD kana anti-TNF vamiririri. Iyi mishonga inopihwa jekiseni.

Majoini anorwadza zvikuru anogona kurapwa nemajekiseni esteroid. Izvi zvinoshandiswa kana paine chete kana mashoma majoini anobatanidzwa. Nyanzvi zhinji hadzisi kukurudzira muromo corticosteroids ye psoriatic arthritis. Kushandiswa kwavo kunogona kuwedzera psoriasis uye kukanganisa maitiro emimwe mishonga.

Muzviitiko zvisingawanzoitika, kuvhiyiwa kunogona kudikanwa kugadzirisa kana kutsiva majoini akakuvara.

Vanhu vane kuzvimba kweziso vanofanira kuona ophthalmologist.

Wako mupi anogona kukurudzira kusanganiswa kwekuzorora uye kurovedza muviri. Kurapa kwepanyama kunogona kubatsira kuwedzera kubatana kwekubatana. Iwe unogona zvakare kushandisa kupisa uye kutonhora kurapwa.

Chirwere ichi dzimwe nguva chine hunyoro uye chinobata mashoma mashoma majoini. Nekudaro, mune vanhu vazhinji vane psoriatic arthritis kukuvara kwemajoini kunoitika mukati memakore akati wandei ekutanga. Mune vamwe vanhu, chirwere chakaipisisa chearthritis chinogona kukonzeresa kushanduka kwemaoko, tsoka, uye musana.

Vazhinji vanhu vane psoriatic arthritis iyo isingavandudzike neNSAIDs vanofanirwa kuona iyo rheumatologist, nyanzvi mune arthritis, pamwe chete nedermatologist yeiyo psoriasis.

Kurapa kwekutanga kunogona kudzora marwadzo uye kudzivirira kukuvara kwemajoini, kunyangwe muzviitiko zvakaipa kwazvo.

Fonera mupi wako kana iwe ukaita zviratidzo zveArthritis pamwe ne psoriasis.

Arthritis - psoriatic; Psoriasis - psoriatic yemajoini; Spondyloarthritis - psoriatic arthritis; PsA

• Psoriasis - guttate pamaoko nepachipfuva
• Psoriasis - guttate padama

Bruce IN, Ho PYP. Clinical maficha e psoriatic arthritis. Mu: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. 7th ed. Philadelphia, PA: Elsevier; 2019: chitsuwa 128.

Gladman D, Rigby W, Azevedo VF, uye al. Tofacitinib ye psoriatic arthritis mune varwere vasina kukwana mhinduro kune TNF inhibitors. N Engl J Med. 2017; 377:1525-1536.

Akashatirwa JS, Schöls M, Braun J, et al. Kurapa axial spondyloarthritis uye peripheral spondyloarthritis, kunyanya psoriatic arthritis, kunongedza: 2017 yekuvandudza kwemazano nevepasi rese boka revarwi. Ann Rheum Dis. 2018; 77 (1): 3-17. PMID: 28684559 pubmed.ncbi.nlm.nih.gov/28684559/.

Veale DJ, Orr C. Kutungamira kweporioriatic arthritis. Mu: Hochberg MC, Gravallese EM, Silman AJ, Smolen JS, Weinblatt ME, Weisman MH, eds. Rheumatology. 7th ed. Philadelphia, PA: Elsevier; 2019: chitsiko 131.