Yakajeka segmental glomerulosclerosis

Focal segmental glomerulosclerosis is scar tishu mune yekutswanya unit yeitsvo. Ichi chimiro chinonzi glomerulus. Iyo glomeruli inoshanda sesefa anobatsira muviri kubvisa zvinhu zvinokuvadza. Itsvo yega yega ine zviuru zve glomeruli.

"Focal" zvinoreva kuti mamwe emagetsi anopenya. Zvimwe zvinoramba zvakajairika. "Segmental" zvinoreva kuti chete chikamu chemunhu glomerulus chakakuvara.

Chikonzero che focal segmental glomerulosclerosis inowanzo kuzivikanwa.

Mamiriro acho anokanganisa vese vana nevakuru. Izvo zvinoitika zvishoma zvishoma muvarume nevakomana. Izvo zvakare zvakajairika muAfrican America. Focal segmental glomerulosclerosis inokonzera kusvika kuchina yezviitiko zvese zvephrotic syndrome.

Zvikonzero zvinozivikanwa zvinosanganisira:

• Zvinodhaka zvakadai seheroin, bisphosphonates, anabolic steroids
• Utachiona
• Zvinogara nhaka zvinetso zvemagene
• Kufutisa
• Reflux nephropathy (mamiriro umo urini inoyerera ichidzokera kumashure kubva mudundira kuenda kuitsvo)
• Sickle cell chirwere
• Mimwe mishonga

Zviratidzo zvinogona kusanganisira:

• Foamy weti (kubva yakawandisa mapuroteni mumurini)
• Chido chisina kunaka
• Kuzvimba, kunodaidzwa kunzi edema, kubva kune zvinwiwa zvakachengetwa mumuviri
• Kurera huremu

Anopa hutano anoita bvunzo dzepanyama. Bvunzo iyi inogona kuratidza kuzvimba kwetishu (edema) uye kuwedzerwa kweropa. Zviratidzo zveitsvo (renal) kutadza uye kuwanda kwemvura zvinogona kukura sezvo mamiriro ari kuwedzera kuipa.

Miedzo inogona kusanganisira:

• Itsvo biopsy
• Itsvo basa rekuyedza (ropa uye weti)
• Kuongorora urinal
• Weti microscopy
• Weti mapuroteni

Mishonga inogona kusanganisira:

• Mishonga yekudzora kupisa muviri kwemuviri.
• Mishonga yekudzikisa BP. Mimwe yemishonga iyi inobatsirawo kudzikisa huwandu hweprotein iyo inodira mumuti weti.
• Mishonga yekubvisa yakawandisa fluid (diuretic kana "water piritsi").
• Kudya kwakaderera kwesodium kuderedza kuzvimba uye kudzikira kweropa.

Chinangwa chekurapa ndechekudzora zviratidzo zvephrotic syndrome uye kudzivirira kusingaperi kweitsvo kukundikana. Aya marapirwo anogona kusanganisira:

• Mishonga inorwisa mabhakitiriya kudzora hutachiona
• Kurambidzwa kwemvura
• Kudya kwemafuta mashoma
• Yakaderera- kana ine mwero-protein chikafu
• Vitamin D zvinowedzera
• Dialysis
• Itsvo kuisazve

Chikamu chakakura chevanhu vane focal kana segmental glomerulosclerosis vanozoita isingagumi itsvo kutadza.

Zvinetso zvinogona kusanganisira:

• Kusingaperi itsvo kutadza
• End-danho chirwere cheitsvo
• Utachiona
• Kushaya zvokudya zvinovaka muviri
• Nephrotic chirwere

Fonera mupiki wako kana iwe ukaita zviratidzo zveichi chiitiko, kunyanya kana paine:

• Kupindwa nechando
• Marwadzo pamwe weti
• Yakaderera weti kubuda

Hapana kudzivirira kunozivikanwa.

Chikamu che glomerulosclerosis; Focal sclerosis ine hyalinosis

• Urume urinary system

Appel GB, D'Agati VD. Yepuraimari uye yechipiri (isiri-genetiki) zvikonzero zvekutarisa uye chikamu che glomerulosclerosis. Muna: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Yakakwana Kliniki Nephrology. 6th ed. Philadelphia, PA: Elsevier; 2019: chits. 18.

Appel GB, Radhakrishnan J. Glomerular kusagadzikana uye nephrotic syndromes. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga.25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 121.

Pendergraft WF, Nachman PH, Jennette JC, Falk RJ. Chirwere chepakutanga chinoratidzira. Mune: Skorecki K, Taal MW, Chertow GM, Marsden PA, Yu ASL, eds. Brenner uye Rector Iyo Itsvo. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits.