Autoimmune kusagadzikana

Chirwere chekuzvimiririra chinoitika kana immune system ichirwisa uye nekuparadza hutano hwemuviri nemistake. Kune anopfuura makumi masere marudzi e autoimmune kusagadzikana.

Masero eropa ari mumuviri wemuviri anodzivirira kubva kuzvinhu zvinokuvadza. Mienzaniso inosanganisira mabhakitiriya, mavairasi, chepfu, masero ekenza, uye ropa uye nyama kubva kunze kwemuviri. Izvi zvinhu zvine maantigen. Ma immune immune anogadzira masoja ekudzivirira aya maantigen anoita kuti ikwanise kuparadza zvinhu zvinokuvadza izvi.

Paunenge uine autoimmune kusagadzikana, immune system yako haina kusiyanisa pakati pehutano hwakanaka uye zvinogona kukuvadza maantigen. Nekuda kweizvozvo, muviri unoseta mhinduro inoparadza zvakajairika zvinyama.

Icho chaicho chinokonzera autoimmune kusagadzikana hachizivikanwe. Imwe dzidziso ndeyekuti mamwe ma microorganisms (akadai mabhakitiriya kana mavairasi) kana zvinodhaka zvinogona kukonzera shanduko dzinovhiringidza immune system. Izvi zvinogona kuitika kazhinji muvanhu vane majini anovaita kuti vawedzere kusangana nematambudziko e autoimmune.

An autoimmune kusagadzikana kunogona kukonzera:

• Kuparara kwetinyama yemuviri
• Kukura zvisina kujairika kwenhengo
• Shanduko mune yemuviri basa

An autoimmune kusagadzikana kunogona kukanganisa imwe kana kupfuura nhengo kana mhando dzenyama. Nzvimbo dzinowanzo kukanganiswa ne autoimmune kusagadzikana dzinosanganisira:

• Tsinga
• Zvinobatanidza matishu
• Endocrine glands senge utachiona kana rwatata
• Mapfundo
• Tsandanyama
• Masero matsvuku eropa
• Ganda

Munhu anogona kunge aine zvinopfuura kamwe autoimmune kusagadzikana panguva imwe chete. Zvinowanzoitika autoimmune kusagadzikana zvinosanganisira:

• Addison chirwere
• Chirwere cheCeliac - sprue (gluten-sensitive enteropathy)
• Dermatomyositis
• Graves chirwere
• Hashimoto thyroiditis
• Multiple sclerosis
• Myasthenia gravis
• Anonemia anemia
• Reactive arthritis
• Rheumatoid arthritis
• Sjögren chirwere
• Systemic lupus erythematosus
• Tora I chirwere cheshuga

Zviratidzo zvinosiyana, zvichibva parudzi uye nzvimbo yeanokanganisa immune mhinduro. Zviratidzo zvakajairika zvinosanganisira:

• Kuneta
• Kupindwa nechando
• Kazhinji kurwara kunzwa (malaise)
• Joint kurwadziwa
• Mapundu

Anopa hutano anoita bvunzo dzepanyama. Zviratidzo zvinoenderana nerudzi rwechirwere.

Miedzo inogona kuitwa kuti uongorore autoimmune kusagadzikana inosanganisira:

• Antinuclear antibody bvunzo
• Autoantibody bvunzo
• CBC
• Yakakwana metabolic pani
• C-inoshanda mapuroteni (CRP)
• Erythrocyte sedimentation chiyero (ESR)
• Kuongorora urinal

Zvinangwa zvekurapa ndezvekuti:

• Chengetedza maitiro ekuzvidzivirira
• Chengetedza kugona kwemuviri kurwisa chirwere
• Deredza zviratidzo

Mishonga inoenderana nechirwere chako nezviratidzo. Mhando dzokurapa dzinosanganisira:

• Inowedzera kutsiva chinhu chisina muviri, senge utachiona kemikari, vhitamini B12, kana insulin, nekuda kwechirwere chemuviri.
• Kuwedzerwa ropa kana ropa rakakanganiswa
• Kurapa kwepanyama kubatsira nekufamba kana mapfupa, majoini, kana mhasuru zvakakanganiswa

Vanhu vazhinji vanotora mishonga yekuderedza immune system mhinduro isina kujairika. Izvi zvinowanzozodaidzwa kuti immunosuppressive mishonga. Mienzaniso inosanganisira corticosteroids (senge prednisone) uye nonsteroid zvinodhaka senge azathioprine, cyclophosphamide, mycophenolate, sirolimus, kana tacrolimus. Mishonga yakanangwa yakadai seya tumor necrosis factor (TNF) blockers uye Interleukin inhibitors inogona kushandiswa kune zvimwe zvirwere.

Mhedzisiro yacho inoenderana nechirwere. Zvizhinji zvezvirwere zvekudzivirira muviri ndezvenguva refu, asi mazhinji anogona kudzorwa pamwe nekurapwa.

Zviratidzo zve autoimmune kusagadzikana zvinogona kuuya nekuenda. Kana zviratidzo zvikawedzera, zvinonzi kupisa-up.

Matambudziko anoenderana nechirwere. Mishonga inoshandiswa kudzvinyirira immune immune inogona kukonzera zvakakomba mhedzisiro, senge yakanyanya njodzi yezvirwere.

Fonera wako mupi kana iwe ukaita zviratidzo zve autoimmune kusagadzikana.

Iko hakuna kuzivikanwa kudzivirira kweakawanda autoimmune kusagadzikana.

• Graves chirwere
• Hashimoto's chirwere (chisingaperi thyroiditisitis)
• Multiple sclerosis
• Rheumatoid arthritis
• Rheumatoid arthritis
• Systemic lupus erythematosus
• Synovial fluid
• Rheumatoid arthritis
• Antibodies

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Peakman M, Buckland MS. Iyo immune system uye chirwere. Mune: Kumar P, Clark M, eds. Kumar uye Clarke's Clinical Medicine. 9th ed. Philadelphia, PA: Elsevier; 2017: chits. 8.

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