Kuongorora genetic uye njodzi yako yekenza

Majini mumasero edu anoita mabasa akakosha. Dzinokanganisa bvudzi uye ruvara rwemaziso uye mamwe maitiro akapfuudzwa kubva kumubereki kuenda kumwana. Magen'a anotaurirawo masero kuti agadzire mapuroteni anobatsira muviri kushanda.

Kenza inoitika apo maseru anotanga kuita zvisina kujairika. Muviri wedu une majini anodzivirira kukurumidza maseru kukura uye mamota kubva pakuumbwa. Shanduko mumajini (shanduko) inobvumidza maseru kupatsanuka nekukurumidza uye kuramba achishanda. Izvi zvinotungamira kukura kwegomarara uye mamota. Gene shanduko inogona kunge iri mhedzisiro yekukuvara kwemuviri kana chimwe chinhu chakapfuudzwa mumajini mumhuri yako.

Kuongorora genetic kunogona kukubatsira kuti uone kana uine genet mutation iyo inogona kukonzeresa kune cancer kana iyo inogona kukanganisa dzimwe nhengo mumhuri yako. Dzidza nezvekuti ndeipi kanzira ine kuongororwa kunowanikwa, zvinorehwa nemhedzisiro, uye zvimwe zvinhu zvekufunga usati waedzwa.

Nhasi, isu tinoziva chaicho majini shanduko anogona kukonzera anopfuura makumi mashanu kanzura, uye ruzivo rwuri kukura.

Iyo imwechete geni mutation inogona kusungirirwa pamhando dzakasiyana dzekenza, kwete imwe chete.

• Semuenzaniso, shanduko muBRCA1 uye BRCA2 magene akabatana nekenza yemazamu, gomarara reovari, uye mamwe akawanda kanzura, mune varume nevakadzi. Inenge hafu yevakadzi vanogara nhaka BRCA1 kana BRCA2 magene ekuchinja anozoita gomarara repazamu pazera remakore makumi manomwe.
• Polyps kana kukura pamutsara wekoloni kana rectum kunogona kuve kwakabatana nekenza uye dzimwe nguva kunogona kuve chikamu chehurombo hwakagara nhaka.

Genetic mutations yakabatana nekenza dzinotevera:

• Chipfuva (murume nemukadzi)
• Ovarian
• Prostate
• Pancreatic
• Bonzo
• Leukemia
• Gland yeAdrenal
• Utachiona
• Endometrial
• Colorectal
• Utumbo hudiki
• Renal chiuno
• Chiropa kana biliary turakiti
• Dumbu
• Ubongo
• Ziso
• Melanoma
• Parathyroid
• Pituitary shwanu
• Itsvo

Zviratidzo zvekuti gomarara rinogona kunge riine chikonzero chinosanganisira:

• Gomarara rinoonekwa pazera diki pane zvakajairwa
• Mhando dzinoverengeka dzekenza mumunhu mumwe chete
• Gomarara rinokura munhengo mbiri dzakabatana, senge ese mazamu kana itsvo
• Vanoverengeka veropa hama vane imwecheteyo kenza
• Zviitiko zvisingawanzoitika zveimwe mhando yekenza, senge kenza yemazamu mumurume
• Kuremara kwekuzvarwa kwakabatana necancer yekenza
• Kuva chikamu cheboka redzinza kana redzinza rine njodzi huru yemamwe kanzira pamwe nechero chimwe kana zvakawanda zvepamusoro

Iwe unogona kutanga uine kuongororwa kuti uone huwandu hwengozi yako. Anopa mazano anobva arayira bvunzo mushure mekutaura newe nezve hutano hwako uye zvaunoda. Vanachipangamazano veGenetic vanodzidziswa kukuzivisa iwe pasina kuyedza kutungamira sarudzo yako. Nenzira iyoyo iwe unogona kusarudza kana kuyedzwa kwakakukodzera.

Kuyedza kunoshanda sei:

• Ropa, mate, maseru eganda, kana amniotic fluid (yakatenderedza fetus iri kukura) inogona kushandiswa kuyedzwa.
• Samples anotumirwa kune lab iyo inonyanya kuongorora magene. Zvinogona kutora vhiki dzinoverengeka kuti uwane mhedzisiro.
• Paunenge iwe wawana mhedzisiro, iwe unozotaura neanopa chipangamazano nezve izvo zvavanogona kureva kwauri.

Kunyangwe iwe uchikwanisa kuodha kuyedzwa uri wega, iri zano rakanaka kushanda neanopa chipangamazano. Ivo vanogona kukubatsira iwe kuti unzwisise mabhenefiti uye kukwana kwemhedzisiro yako, uye zvinogona kuita zviito. Zvakare, ivo vanokwanisa kukubatsira iwe kuti unzwisise zvazvinogona kureva kunhengo dzemhuri, uye nekuvarayira zvakare.

Iwe unozofanirwa kusaina fomu rekubvumirwa uine ruzivo usati waedzwa.

Kuedzwa kunogona kukwanisa kukuudza kana iwe uine genetic mutation iyo yakabatana neboka rekenza. Mhedzisiro yakanaka inoreva kuti une njodzi yakawedzera yekutora iyo kanzira.

Nekudaro, mhedzisiro yakanaka hazvireve kuti uchaita gomarara. Majini akaomarara. Iyo geni rimwe rinogona kukanganisa mumwe munhu zvakasiyana neumwe.

Ehezve, mhedzisiro yakaipa haireve kuti hauzombowana gomarara. Iwe unogona kunge usiri panjodzi nekuda kwemajini ako, asi iwe uchiri kugona kuita cancer kubva kune chakasiyana chikonzero.

Mhedzisiro yako inogona kunge isiri nyore senge yakanaka uye isina kunaka. Muedzo unogona kuwana shanduko mune geni iro nyanzvi dzisina kuona senjodzi yekenza panguva ino. Iwe unogona zvakare kuve yakasimba nhoroondo yemhuri yekamwe gomarara uye yakaipa mhedzisiro yekuchinja kwemajini. Wako genetic chipangamazano achatsanangura aya marudzi emhedzisiro.

Ikoko zvakare kunogona kuve nekumwe kuchinja kwemajini kusati kwazivikanwa. Iwe unogona chete kuongororwa kuongororwa kwemajini kwatinoziva nezvazvino. Basa rinoenderera mberi nekuita kuti kuongorora kwemajini kuve neruzivo uye kwakaringana.

Kufunga kana kuve nekuongororwa kwemajini isarudzo yemunhu. Iwe ungangoda kufunga nezve genetic kuongorora kana:

• Une hama dzepedyo (amai, baba, hanzvadzi, hama, vana) vakave nekenza imwechete.
• Vanhu vari mumhuri yako vakave nekenza yakabatana neye gene mutation, senge kenza yemazamu kana ovari.
• Nhengo dzemhuri yako dzaive nekenza pazera diki pane zvakajairwa kune iyo mhando yekenza.
• Iwe wave uine kenza yekuongorora mhedzisiro iyo inogona kunongedzera kune echisikigo anokonzera
• Nhengo dzemhuri dzakave nekuongororwa kwemajini uye dzakave nemhedzisiro.

Kuedzwa kunogona kuitwa muvakuru, vana, uye kunyangwe mune iri kukura fetus neembryo.

Ruzivo iwe rwaunowana kubva kugeneral test rinogona kubatsira kutungamira sarudzo dzako dzehutano uye sarudzo yemararamiro. Iko kune zvimwe zvakanaka zvekuziva kana iwe uchitakura geni shanduko. Iwe unogona kukwanisa kudzikisa njodzi yako yekenza kana kuidzivirira ne:

• Kuitwa oparesheni.
• Kuchinja mararamiro ako.
• Kutanga cancer cancer screenings. Izvi zvinogona kukubatsira kuti ubate kenza kare, apo inogona kurapwa zviri nyore.

Kana iwe uchitova nekenza, kuyedzwa kunogona kubatsira kutungamira kwakanangwa kurapwa.

Kana iwe uri kufunga nezvekuyedza, heino mimwe mibvunzo iwe yaungangoda kubvunza yako mupi wezvehutano kana wezano majini:

• Kuongorora majini kwakandinakira here?
• Kuedzwa kupi kuchaitwa? Kwakajeka sei kuyedzwa?
• Mhedzisiro yacho ichandibatsira here?
• Mhinduro idzi dzinogona kundibata sei pamoyo?
• Ndeipi njodzi yekupfuudza shanduko kuvana vangu?
• Ruzivo urwu ruchabata sei hama dzangu nehukama?
• Ruzivo rwacho nderwega here?
• Ndiani achakwanisa kuwana ruzivo?
• Ndiani achabhadhara kuyedzwa (uko kunogona kudhura zviuru zvemadhora)?

Usati waedzwa, ita shuwa kuti iwe unonzwisisa maitiro uye izvo mhedzisiro inogona kureva iwe nemhuri yako.

Iwe unofanirwa kufonera mupi wako kana iwe:

• Uri kutarisa kuongorora kwemajini
• Ungade kukurukura mhedzisiro yekuongororwa kwemajini

Genetic mutations; Nhaka dzinoshanduka; Kuongorora genetic - gomarara

American Cancer Society webhusaiti. Kunzwisisa kuongororwa kwemajini kwekenza. www.cancer.org/cancer/cancer-causes/genetics/understanding-genetic-testing-for-cancer.html. Yakagadziridzwa Kubvumbi 10, 2017. Yakasvika Gumiguru 6, 2020.

National Cancer Institute webhusaiti. Kuchinja kwe BRCA: njodzi yekenza uye kuongororwa kwemajini. www.cancer.gov/about-cancer/causes-prevention/genetics/brca-fact-sheet. Yakagadziridzwa Ndira 30, 2018. Yakasvika Gumiguru 6, 2020.

National Cancer Institute webhusaiti. Kuongorora kwegeneti yekenza nhaka yekenza syndromes. www.cancer.gov/about-cancer/causes-prevention/genetics/genetic-testing-fact-sheet. Yakagadziridzwa Kurume 15, 2019. Yakasvika Gumiguru 6, 2020.

Walsh MF, Cadoo K, Salo-Mullen EE, Dubard-GaultM, Stadler ZK, Offit K.Genetic zvinhu: nhaka yekenza inotangira syndromes. Mune: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020: chits. 13.

• Gomarara
• Kuongorora kweGenetic