Kenza yeEndometrial

Kenza yeEndometrial igomarara iro rinotanga mu endometrium, iyo lining yechibereko (chibereko).

Endometrial kenza ndiyo yakajairika mhando yemukenza wechibereko. Chikonzero chaicho chekenza yemendometri hazvizivikanwe. Iyo yakawedzera nhanho yeestrogen hormone inogona kutora chinzvimbo. Izvi zvinokurudzira kuwanda kwemukati wechibereko. Izvi zvinogona kutungamira mukuwandisa kwakanyanya kweiyo endometrium nekenza.

Kazhinji kenza yemendometrial inoitika pakati pemakore makumi matanhatu nemakumi manomwe. Zviitiko zvishoma zvinogona kuitika makore makumi mana asati apfuura.

Izvi zvinotevera zvinhu zvine chekuita nemahormone ako zvinowedzera mukana wako wekenza yemendometri:

• Estrogen kutsiva kurapa pasina kushandisa progesterone
• Nhoroondo ye endometrial polyps
• Kakawanda nguva
• Usambove nepamuviri
• Kufutisa
• Chirwere cheshuga
• Polycystic ovary syndrome (PCOS)
• Kutanga kuenda kumwedzi pazera diki (pamberi pemakore gumi nemaviri)
• Kutanga kuenda kumwedzi mushure memakore makumi mashanu
• Tamoxifen, mushonga unoshandiswa pakurapa kenza yemazamu

Vakadzi vane inotevera mamiriro vanoita kunge vari panjodzi yakanyanya yekenza yemendometri:

• Colon kana kenza yemazamu
• Gallbladder chirwere
• Kuwedzera kweropa

Zviratidzo zvekenza yemendometri zvinosanganisira:

• Kubuda ropa zvisina kujairika kubva mukati memukadzi, kusanganisira kubuda ropa pakati penguva kana kuona / kubuda ropa mushure mekuguma kuenda kumwedzi
• Yakanyanya kureba, inorema, kana inowanzoitika zvikamu zvekubuda kweropa mushure memakore makumi mana
• Kutambudzika kwepazasi kwepamuviri kana kupwanya kwechiuno

Pakati pematanho ekutanga echirwere, kuongororwa kwepamuviri kunowanzoitika.

• Mumatanho epamberi, panogona kunge paine shanduko muhukuru, chimiro, kana kunzwa kwechibereko kana zvivakwa zvakapoteredza.
• Pap smear (inogona kukwidza fungidziro yekenza yemendometri, asi isingazviongorore)

Zvichienderana nezviratidzo zvako uye zvimwe zvakawanikwa, mimwe miedzo inogona kudikanwa. Zvimwe zvinogona kuitwa muhofisi yemupi wezvehutano. Zvimwe zvinogona kuitwa kuchipatara kana nzvimbo yekuvhiya:

• Endometrial biopsy: Uchishandisa catheter diki kana nhete (chubhu), nyama inotorwa kubva muchigadziko chechibereko (endometrium). Masero anoongororwa pasi pe microscope kuti aone kana paine anoita seasina kujairika kana kenza.
• Hysteroscopy: Chishina chakatetepa-senge chishandiso chakaiswa kuburikidza nemukadzi uye nekuvhurwa kwechibereko. Inoita kuti mupi aone mukati mechibereko.
• Ultrasound: Mafungu ezwi anoshandiswa kugadzira mufananidzo wenhengo dzechiuno. Iyo ultrasound inogona kuitwa mudumbu kana muchikadzi. Iyo ultrasound inogona kuona kana iyo lining yechibereko ichiita senge isina kujairika kana yakasimbiswa.
• Sonohysterography: Fluid inoiswa muchibereko kuburikidza nechubhu nhete, nepo vaginal ultrasound mifananidzo inogadzirwa muchibereko. Maitiro aya anogona kuitwa kuti uone kuvepo kwechero chisina kujairika chibereko chechibereko icho chingave chiri chiratidzo chegomarara.
• Magnetic resonance imaging (MRI): Mune iyi bvunzo yekufungidzira, magineti ane simba anoshandiswa kugadzira mifananidzo yenhengo dzemukati.

Kana gomarara rikawanikwa, kuongororwa kwekufungidzira kunogona kuitwa kuti uone kana gomarara rapararira kune dzimwe nhengo dzemuviri. Uku kunodaidzwa kunzi staging.

Matanho ekenza yemendometriari ndeaya:

• Stage 1: Kenza iri chete muchibereko.
• Stage 2: Kenza iri muchibereko uye muromo wechibereko.
• Stage 3: Kenza yakapararira kunze kwechibereko, asi kwete kupfuura iyo chaiyo pelvis nzvimbo. Kenza inogona kusanganisira ma lymph node mumapapiro kana padyo neaorta (iyo tsinga huru mudumbu).
• Stage 4: Kenza yakapararira mukati memukati memukati, dundira, dumbu, kana dzimwe nhengo.

Gomarara rinorondedzerwawo segiredhi 1, 2, kana 3. Giredhi 1 ndiyo ine hukasha, uye giredhi 3 ndiyo ine hukasha. Hasha zvinoreva kuti gomarara rinokura nekupararira nekukurumidza.

Sarudzo dzekurapa dzinosanganisira:

• Kuvhiya
• Radiation kurapa
• Chemotherapy

Kuvhiya kubvisa chibereko (hysterectomy) kunogona kuitwa mumadzimai ane chirwere chekutanga chegomarara. Chiremba anogona zvakare kubvisa machubhu nemazai.

Kuvhiya kwakabatana ne radiation radiation ndeimwe nzira yekurapa. Inowanzo shandiswa kuvakadzi vane:

• Stage 1 chirwere chine mukana wakakura wekudzoka, chakapararira kune lymph node, kana iri giredhi 2 kana 3
• Chikamu chechipiri chirwere

Chemotherapy kana hormonal therapy inogona kutariswa mune dzimwe nguva, kazhinji kune avo vane chirwere chechitatu uye chechina.

Unogona kudzikisira kushushikana kwehurwere nekujoinha boka rekutsigira gomarara. Kugovana nevamwe vane zvakajairika zviitiko uye matambudziko zvinogona kukubatsira kuti usazonzwa kusurukirwa.

Kenza yeEndometrial inowanzoongororwa padanho rekutanga.

Kana gomarara risina kupararira, 95% yevakadzi vapenyu mushure memakore mashanu. Kana gomarara rapararira kunhengo dziri kure, vangangoita 25% yevakadzi vachiri vapenyu mushure memakore mashanu.

Zvinetso zvinogona kusanganisira chero yeanotevera:

• Anemia nekuda kwekurasikirwa neropa (usati waongororwa)
• Perforation (hole) yechibereko, iyo inogona kuitika panguva yeD uye C kana endometrial biopsy
• Matambudziko kubva pakuvhiyiwa, radiation, uye chemotherapy

Dana kuti usangane nemupi wako kana iwe uine chero chinotevera:

• Chero kubuda ropa kana kuona kunoitika mushure mekutanga kuenda kumwedzi
• Kubuda ropa kana kuona mushure mekusangana kana kubata
• Kubuda ropa kwenguva refu kupfuura mazuva manomwe
• Kusarongeka kuenda kumwedzi kunoitika kaviri pamwedzi
• Kubuda kutsva mushure mekuguma kuenda kumwedzi kwatanga
• Kurwadziwa kwepelvic kana kupwanya kusingaendi

Iko hakuna bvunzo inoshanda yekubvunzurudza cancer endometrial (uterine).

Vakadzi vane njodzi pazvinhu zve endometrial cancer vanofanira kuteverwa padhuze nachiremba vavo. Izvi zvinosanganisira vakadzi vari kutora:

• Estrogen kutsiva kurapa pasina progesterone kurapa
• Tamoxifen kweanopfuura makore maviri

Kazhinji bvunzo dzechiuno, Pap smears, vaginal ultrasound, uye endometrial biopsy inogona kutariswa mune dzimwe nguva.

Ngozi yekenza yemendometri yakaderedzwa ne:

• Kuchengeta huremu hwese
• Kushandisa mapiritsi ekudzivirira kubereka kweanopfuura gore

Endometrial adenocarcinoma; Uterine adenocarcinoma; Kenza yechibereko; Adenocarcinoma - endometrium; Adenocarcinoma - chibereko; Kenza - uterine; Kenza - endometrium; Kenza yeUterine corpus

• Hysterectomy - mudumbu - kubuda
• Hysterectomy - laparoscopic - kubuda
• Hysterectomy - kusangana nekutsi kwemukadzi - kubuda
• Pelvic radiation - kubuda

• Pelvic laparoscopy
• Mukadzi wekubereka anatomy
• D naC
• Endometrial biopsy
• Hysterectomy
• Uterus
• Kenza yeEndometrial

Armstrong DK. Gynecologic kenza. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chits. 189.

Boggess JF, Kilgore JE, Tran AQ. Kenza yechibereko. Mune: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020: chits. 85.

Morice P, Leary A, Creutzberg C, Abu-Rustum N, Darai E. Kenza yeEndometri. Lancet. 2016; 387 (10023): 1094-1108. PMID: 26354523 pubmed.ncbi.nlm.nih.gov/26354523/.

National Cancer Institute webhusaiti. Endometrial cancer kurapwa kurapwa (PDQ) -health nyanzvi vhezheni. www.cancer.gov/types/uterine/hp/endometrial-treatment-pdq. Yakagadziridzwa Zvita 17, 2019. Yakasvika paKurume 24, 2020.

National Yakakwana Cancer Network webhusaiti. NCCN kiriniki yekudzidzira maitiro mune oncology (NCCN nhungamiro): uterine neoplasms. Shanduro 1.2020. www.nccn.org/professionals/physician_gls/pdf/uterine.pdf. Yakagadziridzwa Kurume 6, 2020. Yakasvika paKurume 24, 2020.