Progeria

Progeria isingawanzoitika geni mamiriro ayo anounza kukwegura nekukurumidza muvana.

Progeria chiitiko chisingawanzoitika. Iyo inoshamisa nekuti zviratidzo zvayo zvine simba zvakafanana nekukwegura kwevanhu, asi zvinoitika muvana vadiki. Muzviitiko zvakawanda, haina kupfuudzwa kuburikidza nemhuri. Izvo hazviwanzo kuonekwa mumwana anopfuura mumwe chete mumhuri.

Zviratidzo zvinosanganisira:

• Kukura kwekutadza mukati megore rekutanga rehupenyu
• Chiso chakamanikana, chakakwinyika kana kuunyana
• Mhanza
• Kushaya tsiye uye eyelashes
• Pfupi chimiro
• Musoro muhombe wehukuru hwechiso (macrocephaly)
• Vhura nzvimbo nyoro (fontanelle)
• Shaya diki (micrognathia)
• Yakaoma, ine ganda rakaonda
• Yakatemerwa renji yekufamba
• Mazino - kunonoka kana kusipo kuumbwa

Anopa hutano anoita bvunzo dzepanyama uye odha bvunzo dzemarabhoritari. Izvi zvinogona kuratidza:

• Insulin kuramba
• Ganda rinoshanduka rakafanana neiro rinoonekwa mu scleroderma (iyo inosanganisa nyama inoomesera uye kuomesa)
• Kazhinji zvakajairika cholesterol uye triglyceride mazinga

Kuora mwoyo kwepfungwa kunogona kuratidza zviratidzo zvekutanga atherosclerosis yemidzi yeropa.

Genetic kuyedza kunogona kuona shanduko mujeni (LMNA) izvo zvinokonzeresa progeria.

Iko hakuna chaiwo marapirwo eprogeria. Aspirin uye statin mishonga inogona kushandiswa kudzivirira kubva pakurwara kwemoyo kana sitiroko.

Progeria Research Foundation, Inc. - www.progeriaresearch.org

Progeria inokonzera kufa kwekutanga. Vanhu vane mamiriro acho kazhinji vanongorarama chete kumakore avo ekuyaruka (avhareji yeupenyu hwemakore gumi nemana). Nekudaro, vamwe vanogona kurarama mukati mavo ekutanga makumi maviri. Chikonzero cherufu chinowanzoenderana nemoyo kana sitiroko.

Zvinetso zvinogona kusanganisira:

• Kurwadziwa kwemoyo (myocardial infarction)
• Kurohwa

Fonera wako mupi kana mwana wako asingaite kunge ari kukura kana kukura zvakajairika.

Hutchinson-Gilford progeria chirwere; HGPS

• Coronary tsinga kuvharika

Gordon LB. Hutchinson-Gilford progeria chirwere (progeria). Mune: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chits. 109.

Gordon LB, Brown WT, Collins FS. Hutchinson-Gilford progeria chirwere. GeneReviews. 2015: 1. PMID: 20301300 www.ncbi.nlm.nih.gov/pubmed/20301300. Yakagadziridzwa Ndira 17, 2019. Yakasvika muna Chikunguru 31, 2019.