Adrenocortical carcinoma

Adrenocortical carcinoma (ACC) kenza yemadrenal glands. Idzo adrenal gland idiki mbiri dzakaumbwa-katatu. Imwe gland iri pamusoro petsvo imwe neimwe.

ACC inowanzoitika muvana vadiki pane makore mashanu ekuberekwa uye vakuru vane makore makumi mana nemakumi mashanu.

Mamiriro acho anogona kuve akabatanidzwa necancer syndrome inopfuudzwa kuburikidza nemhuri (nhaka). Vese varume nevakadzi vanogona kukura iri bundu.

ACC inogona kuburitsa mahormone cortisol, aldosterone, estrogen, kana testosterone, pamwe nemamwe mahormone. Mune vakadzi bundu rinowanzoburitsa mahormone aya, ayo anogona kutungamira kune echirume hunhu.

ACC ishoma kwazvo. Chikonzero hachizivikanwe.

Zviratidzo zvekuwedzera cortisol kana mamwe adrenal gland mahormoni anogona kusanganisira:

• Mafuta, akakomberedzwa hump kumusoro kumusana pazasi pehuro (nyati hump)
• Yakapetwa, yakatenderedzwa kumeso nematama akasviba (kumeso kwemwedzi)
• Kufutisa
• Kukura kwakadzikira (chimiro chipfupi)
• Virilization - kutaridzika kwehunhu hwechirume, kusanganisira kuwedzera bvudzi remuviri (kunyanya kumeso), pubic vhudzi, acne, kudzika kwezwi, uye kuwedzerwa clitoris (vakadzi)

Zviratidzo zvekuwedzera aldosterone zvakafanana nezviratidzo zvepasi potasium, uye zvinosanganisira:

• Tsandanyama tsandanyama
• Kushaya simba
• Marwadzo mudumbu

Anopa hutano anoita bvunzo dzepanyama uye obvunza nezve zviratidzo zvako.

Kuongororwa kweropa kuchaitwa kuongorora huwandu hwehomoni:

• ACTH chikamu chichava chakaderera.
• Chikamu cheAldosterone chichava chakakwirira.
• Chikamu cheCortisol chichava chakakwirira.
• Potassium level ichave yakaderera.
• Mahomoni echirume kana echikadzi anogona kunge akareba zvakanyanya.

Kufungidzira bvunzo dzemudumbu kunogona kusanganisira:

• Ultrasound
• CT scan
• MRI
• PET scan

Kunyanya kurapwa kuvhiyiwa kubvisa bundu. ACC haigone kuvandudza ne chemotherapy. Mishonga inogona kupihwa kudzikisa kugadzirwa kwecortisol, iyo inokonzeresa akawanda ezviratidzo.

Mhedzisiro yacho inoenderana nekuti chirwere chinogadzirwa nekukurumidza zvakadii uye kuti bundu racho rapararira here (metastasized). Mamota akapararira anowanzo kutungamira kurufu mukati memakore matatu kusvika matatu.

Bundu rinogona kupararira kuchiropa, pfupa, mapapu, kana dzimwe nzvimbo.

Fonera waunopa kana iwe kana mwana wako aine zviratidzo zveACC, Cushing syndrome, kana kutadza kukura.

Bundu - adrenal; ACC - adrenal

• Endocrine masero
• Adrenal metastases - CT scan
• Adrenal Tumor - CT

Allolio B, Fassnacht M. Adrenocortical carcinoma. Muna: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Vakuru uye Chiremba. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 107.

National Cancer Institute webhusaiti. Adrenocortical carcinoma kurapwa (Adult) (PDQ) - hutano nyanzvi vhezheni. www.cancer.gov/types/adrenocortical/hp/adrenocortical-treatment-pdq. Yakagadziridzwa Mbudzi 13, 2019. Yakasvika Gumiguru 14, 2020.