Mapuroteni electrophoresis - serum

Iyi yebvunzo bvunzo inoyera mhando dzeprotein mune iyo yemvura (serum) chikamu cheropa sampuli. Urume uhwu hunonzi serum.

Muenzaniso weropa unodiwa.

Mubazi, nyanzvi inoisa muyero weropa papepa rakakosha uye woisa magetsi. Mapuroteni anofamba papepa uye ogadzira mabhendi anoratidza huwandu hwepuroteni yega yega.

Iwe unogona kukumbirwa kuti usadye kana kunwa kwemaawa gumi nemaviri pamberi pekuedzwa uku.

Mimwe mishonga inogona kukanganisa mhedzisiro yeiyi bvunzo. Anokuchengetedza hutano anokuudza kana uchifanira kurega kutora chero mishonga. Usamise chero mushonga usati wataura nemupi wako.

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanongonzwa kubaya kana kubaya. Mushure meizvozvo, panogona kuve nekurohwa kana kupwanya zvishoma. Izvi zvinokurumidza kuenda.

Mapuroteni anogadzirwa kubva kumaamino acids uye akakosha zvikamu zveese maseru uye nyama. Kune mhando dzakasiyana dzemapuroteni mumuviri, uye ane mabasa mazhinji akasiyana. Mienzaniso yemapuroteni anosanganisira enzyme, mamwe mahormone, hemoglobin, yakaderera-density lipoprotein (LDL, kana yakaipa cholesterol), nezvimwe.

Serum mapuroteni anoiswa se albumin kana globulins. Albumin ndiyo protein yakawandisa mune iyo serum. Inotakura mamorekuru mazhinji. Izvo zvakakoshawo kuti uchengetedze mvura kubva pakubuda kubva mumidziyo yeropa ichienda kumatishu.

Globulins akapatsanurwa kuita alpha-1, alpha-2, beta, uye gamma globulins. Muzhinji, alpha uye gamma globulin protein mazinga anowedzera kana paine kuzvimba mumuviri.

Lipoprotein electrophoresis inosarudza huwandu hwemapuroteni akaumbwa nemapuroteni nemafuta, anonzi lipoproteins (senge LDL cholesterol).

Akajairika kukosha maseru ndeaya:

• Yakazara mapuroteni: 6.4 kusvika 8.3 magiramu pa deciliter (g / dL) kana 64 kusvika 83 gramu paita (g / L)
• Albumin: 3.5 kusvika 5.0 g / dL kana 35 kusvika 50 g / L.
• Alpha-1 globulin: 0.1 kusvika 0.3 g / dL kana 1 kusvika 3 g / L
• Alpha-2 globulin: 0.6 kusvika 1.0 g / dL kana 6 kusvika 10 g / L.
• Beta globulin: 0.7 kusvika 1.2 g / dL kana 7 kusvika 12 g / L.
• Gamma globulin: 0.7 kusvika 1.6 g / dL kana 7 kusvika 16 g / L

Iyi mienzaniso iripamusoro zviyero zvakajairika zvemhedzisiro yeiyi bvunzo. Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Mamwe marabhu anoshandisa zviyero zvakasiyana kana kuyedza akasiyana sampuli. Taura nemupi wako nezve zvinoreva mhedzisiro yako.

Kupera kwepuroteni kwakazara kunogona kuratidza:

• Kurasikirwa zvisina kujairika kweprotein kubva munzira yekugaya kana kusakwanisa kwenzvimbo yekudya kunotora mapuroteni (protein-kurasikirwa enteropathy)
• Kushaya zvokudya zvinovaka muviri
• Itsvo kusagadzikana kunonzi nephrotic syndrome
• Kupwanya kwechiropa uye kushomeka kwechiropa basa (cirrhosis)

Kuwedzera alpha-1 globulin mapuroteni anogona kunge ari nekuda kwe:

• Chirwere chakakomba chinopisa
• Gomarara
• Chirwere chisingaperi chirwere (semuenzaniso, rheumatoid arthritis, SLE)

Kupera alpha-1 globulin mapuroteni anogona kunge ari chiratidzo che:

• Alpha-1 antitrypsin kushomeka

Yakawedzera alpha-2 globulin mapuroteni anogona kuratidza a:

• Kuzvimba kwakanyanya
• Kupora kusingaperi

Yakaderera alpha-2 globulin mapuroteni anogona kuratidza:

• Kuputsika kwemasero matsvuku eropa (hemolysis)

Kuwedzera beta globulin mapuroteni anogona kuratidza:

• Dambudziko iro muviri une matambudziko ekuputsa mafuta (semuenzaniso, hyperlipoproteinemia, yemhuri hypercholesterolemia)
• Estrogen kurapa

Kupera beta globulin mapuroteni anogona kuratidza:

• Chikamu chisina kujairika cheLDL cholesterol
• Kushaya zvokudya zvinovaka muviri

Kuwedzera kwe gamma globulin mapuroteni anogona kuratidza:

• Kenza yeropa, inosanganisira akawanda myeloma, Waldenström macroglobulinemia, lymphomas, uye chisingaperi lymphocytic leukemias
• Chirwere chisingaperi chirwere (semuenzaniso, rheumatoid arthritis)
• Hutachiona hutachiona
• Chirwere chechiropa chisingaperi

Pane njodzi shoma inosanganisirwa nekutorwa kweropa rako. Tsinga uye tsinga zvinosiyana muhukuru kubva kumunhu kuenda kune mumwe, uye kubva kune rimwe divi remuviri kuenda kune rimwe. Kutora ropa kubva kune vamwe vanhu kunogona kunge kwakaoma kupfuura kubva kune vamwe.

Dzimwe njodzi dzinosangana nekutorwa kweropa idiki, asi dzinogona kusanganisira:

• Kuwedzera kubuda ropa
• Kufenda kana kunzwa kushaya musoro
• Akawanda punctures ekutsvaga mutsinga
  
• Hematoma (kuwanda kweropa pasi peganda)
• Utachiona (hushoma njodzi chero nguva ganda parinovhunika)

SPEP

• Kuongorora ropa

Chernecky CC, Berger BJ. Mapuroteni electrophoresis - serum. Mune: Chernecky CC, Berger BJ, eds. Rabhoritari Kuyedza uye Maitiro Ekuongorora. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 917-920.

Munshi NC, Jagannath S. Plasma sero neoplasms. Muna: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Misimboti uye Maitiro. 7th ed. Philadelphia, PA: Elsevier; 2018: chits. 86.

Warner EA, Herold AH. Kuturikira bvunzo dzemarabhoritari. Mune: Rakel RE, Rakel DP, eds. Chinyorwa cheMhuri Mishonga. 9th ed. Philadelphia, PA: Elsevier; 2016: chitsiko 14.