17-Hydroxyprogesterone

Zvemukati

• Chii chinonzi 17-hydroxyprogesterone (17-OHP) bvunzo?
• Chii chinoshandiswa?
• Nei ini ndichida 17-OHP bvunzo?
• Chii chinoitika panguva ye 17-OHP bvunzo?
• Ndichafanira here kuita chero chinhu kugadzirira bvunzo?
• Pane here njodzi kune bvunzo?
• Zvinorevei mhedzisiro yacho?
• Pane chimwe chinhu here chandinofanira kuziva nezve 17-OHP bvunzo?
• Zvinyorwa

Chii chinonzi 17-hydroxyprogesterone (17-OHP) bvunzo?

Uyu muyedzo unoyera huwandu hwe17-hydroxyprogesterone (17-OHP) muropa. 17-OHP ihormone inogadzirwa neadrenal glands, maviri magezi ari pamusoro peitsvo. Iyo adrenal gland inogadzira mahormone akati wandei, kusanganisira cortisol. Cortisol yakakosha pakuchengetedza BP, shuga yeropa, uye mamwe mabasa ezvirwere zvemuviri. 17-OHP inogadzirwa sechikamu chegadziriro yekugadzira cortisol.

Chiyero che17-OHP chinobatsira kuongorora chisingawanzoitika chirwere chinonzi gengenital adrenal hyperplasia (CAH). MuCAH, shanduko yemajini, inozivikanwa sekuchinja, inodzivirira iyo adrenal gland kubva mukugadzira yakakwana cortisol. Sezvo madrenal gland anoshanda nesimba kuti awedzere cortisol, ivo vanogadzira yakawedzera 17-OHP, pamwe chete nemamwe mahormone echirume.

CAH inogona kukonzera kukura zvisina kujairika kwenhengo dzepabonde uye hunhu hwepabonde. Zviratidzo zvechirwere zvinobva pane zvinyoro kusvika kune zvakanyanya. Kana ikasarapwa, mafomu akaomarara eCAH anogona kukonzera matambudziko akakura, anosanganisira kushomeka kwemvura, kukwira kweropa, uye kurova kwehana kusingaite

Mamwe mazita: 17-OH progesterone, 17-OHP

Chii chinoshandiswa?

Chiyero che17-OHP chinowanzo shandiswa kuongorora CAH muvacheche. Inogona zvakare kushandiswa ku:

• Ongorora CAH muvana vakura uye vanhu vakuru vanogona kunge vaine chimiro chakaomarara chechirwere. Mune yakaoma CAH, zviratidzo zvinogona kuratidza gare gare muhupenyu, kana dzimwe nguva kwete zvachose.
• Tarisa kurapwa kweCAH

Nei ini ndichida 17-OHP bvunzo?

Mwana wako anoda bvunzo ye17-OHP, kazhinji mukati memazuva 1-2 mushure mekuzvarwa. 17-OHP kuyedza kweCAH iko zvino kunodikanwa nemutemo sechikamu chekuongororwa kwevana vachangoberekwa. Kuzvarwa patsva kuongororwa kweropa kuri nyore kunoongorora zvirwere zvakasiyana siyana.

Vana vakura nevakuru vangangodawo kuyedzwa kana vaine zviratidzo zveCAH. Zviratidzo zvichave zvakasiyana zvichienderana nekuti chirwere chakakomba zvakadii, zera rinoonekwa zviratidzo, uye kana uri murume kana mukadzi.

Zviratidzo zvechimiro chakakomba kwazvo chechirwere chinowanzooneka mukati memasvondo maviri nemaviri mushure mekuzvarwa.

Kana mwana wako akazvarwa kunze kweUnited States uye asina kuwana kuongororwa kwechecheche, vangangoda kuyedzwa kana vaine chimwe kana zvimwe zvezviratidzo zvinotevera:

• Nhengo dzisina kunyatsojeka murume kana mukadzi (genitalia isina kujeka)
• Kupera mvura mumuviri
• Kurutsa uye zvimwe zvinetso zvekudya
• Asina kujairika moyo mutserendende (arrhythmia)

Vana vakura vanogona kunge vasina zviratidzo kusvika pakuyaruka. Mune vasikana, zviratidzo zveCAH zvinosanganisira:

• Nguva dzisina kumwedzi dzekuenda kumwedzi, kana pasina nguva zvachose
• Kutaridzika kwekutanga kwepubic uye / kana ruoko rwebvudzi
• Bvudzi rakawandisa kumeso nemuviri
• Izwi rakadzika
• Yakawedzera clitoris

Muvakomana, zviratidzo zvinosanganisira:

• Yakawedzera nhengo
• Kukura kwekutanga (kuyaruka kwekutanga)

Muvakuru varume nevakadzi, zviratidzo zvinogona kusanganisira:

• Kusabereka (kusakwanisa kubata nhumbu kana kutora mumwe wako nhumbu)
• Zvakanyanya acne

Chii chinoitika panguva ye 17-OHP bvunzo?

Zvekuzvarwa kwekuzvarwa, nyanzvi yehutano inochenesa chitsitsinho chemwana wako nedoro uye inobaya chitsitsinho nekatsono kadiki. Mupiro anozotora madonhwe mashoma eropa uye oisa bhandeji panzvimbo iyi.

Munguva yekuongororwa kweropa kuvana vakura nevakuru, nyanzvi yezvehutano inotora muyero weropa kubva mutsinga iri muruoko rwako, uchishandisa tsono. Mushure mekunge tsono yaiswa, kashoma reropa kanounganidzwa muthubhu yekuyedza kana muhombodo. Unogona kunzwa kakuruma kana tsono ichipinda kana kubuda. Izvi zvinowanzotora maminetsi asingasviki mashanu.

Ndichafanira here kuita chero chinhu kugadzirira bvunzo?

Iko hakuna kwakakosha kugadzirira kunodiwa kune 17-OHP bvunzo.

Pane here njodzi kune bvunzo?

Pane njodzi shoma kwauri kana kumwana wako ane 17-OHP bvunzo. Unogona kunge uine marwadzo mashoma kana kupwanya panzvimbo yakaiswa tsono, asi zviratidzo zvizhinji zvinokurumidza kupera. Mwana wako anogona kunzwa chidiki pacheche kana chitsitsinho chaiswa, uye kupwanya kudiki kunogona kuumba panzvimbo iyi. Izvi zvinofanirwa kuenda nekukurumidza.

Zvinorevei mhedzisiro yacho?

Kana mhedzisiro ichiratidza mazinga epamusoro e17-OHP, ingangoita iwe kana mwana wako ane CAH. Kazhinji, zvakakwirira kwazvo zvinoreva fomu yakaoma kwazvo yemamiriro acho, nepo zvine mwero zvakakwirira zvinowanzoreva fomu yakaoma.

Kana iwe kana mwana wako ari kurapwa CAH, mashoma ezasi e17-OHP anogona kureva kuti kurapwa kuri kushanda. Kurapa kunogona kusanganisira mishonga kutsiva cortisol isipo. Dzimwe nguva kuvhiyiwa kunoitwa kuchinjisa chitarisiko uye mashandiro enhengo dzesikarudzi.

Kana iwe uine mibvunzo nezve ako mhedzisiro kana mhedzisiro yemwana wako, taura nemupi wako wekuchengeta hutano.

Dzidza zvakawanda nezve bvunzo dzemarabhoritari, mareferenzi masosi, uye mhinduro dzekunzwisisa

Pane chimwe chinhu here chandinofanira kuziva nezve 17-OHP bvunzo?

Kana iwe kana mwana wako akaonekwa kuti ane CAH, ungangoda kubvunza kuna chipangamazano wezvechibereko, nyanzvi yakadzidziswa zvakanyanya mumageneti. CAH chirwere chemagene umo vabereki vese vari vaviri vanofanirwa kuve nekuchinja kwemajini kunokonzera CAH. Mubereki anogona kuve anotakura geni, zvinoreva kuti vane jeni asi kazhinji havana zviratidzo zvechirwere. Kana vese vabereki vari vatakuri, mwana wega wega ane 25% mukana wekuva nemamiriro acho.

Zvinyorwa

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Ruzivo ruri pane ino saiti harufanire kushandiswa sekutsiva kwehunyanzvi kurapwa kana kurairwa. Bata mupi wehutano kana iwe uine mibvunzo nezve hutano hwako.