Munyori: Clyde Lopez
Zuva Rekusika: 24 Chikunguru 2021
Gadziridza Zuva: 1 Kubvumbi 2025
Anonim
How does Niacin (B3) Work? (+ Pharmacology)
Vhidhiyo: How does Niacin (B3) Work? (+ Pharmacology)

Zvemukati

Niacin chimiro chevhitamini B3. Inowanikwa mune zvekudya zvakaita sembiriso, nyama, hove, mukaka, mazai, miriwo yakasvibirira, uye zviyo zvezviyo. Niacin inogadzirwawo mumuviri kubva ku tryptophan, iyo inowanikwa muchikafu chine mapuroteni. Kana ikatorwa sechiwedzero, niacin inowanzo kuwanikwa mukubatana nemamwe mavitamini B.

Usavhiringidze niacin neNADH, niacinamide, inositol nicotinate, IP-6, kana tryptophan. Tarisa uone akasiyana ezvinyorwa izvi.

Mafomu ekunyorerwa niacin anotenderwa neU.S.Food and Drug Administration (FDA) yecholesterol yakakwira uye kuwedzera huwandu hwerudzi rwakati rwecholesterol yakanaka, inozivikanwa seHDL. Niacin zvinowedzera uye mishonga yemishonga inotorwawo nemuromo yekudzivirira kushomeka kwevhitamin B3 nemamiriro akafanana se pellagra.

Natural Mishonga Inonzwisisika Dhatabhesi zvinowanisa kushanda kunoenderana neuchapupu hwesainzi zvinoenderana nezviyero zvinotevera: Zvinobudirira, Zvichida Zvinobudirira, Zvichida Zvinobudirira, Zvichida Hazvishande, Zvichida Hazvibatsiri, Hazvibatsiri, uye Huchakwana Huchapupu hweKutara.

Iko kushanda ratings kwe NIACIN zvinotevera:


Zvichida zvinoshanda ...

  • Asina kujairika mazinga echolesterol kana mafuta eropa (dyslipidemia). Mimwe michina yeNiacin inogamuchirwa neU.S.Food and Drug Administration (FDA) sezvigadzirwa zvemishonga yekurapa mazinga asina kujairika emafuta eropa. Izvi zvigadzirwa zvemishonga niacin zvinowanzouya musimba rakakura re500 mg kana yakakwira. Dhayeti yekuwedzera mafomu eniacin kazhinji anouya musimba re250 mg kana zvishoma. Sezvo yakanyanya mwero mizinga yeNiacin inodiwa pakuvandudza cholesterol mazinga, dhayeti yekuwedzera niacin kazhinji haina kukodzera. Niacin inogona kusanganiswa nemamwe cholesterol-achideredza madhiragi kana kudya uye imwechete-drug kurapa zvisina kukwana. Niacin inovandudza cholesterol mazinga, asi haigadzirise mhedzisiro yemoyo yakadai sekurwadziwa kwemoyo nekurohwa.
  • Chirwere chinokonzerwa nekushaikwa kweNiacin (pellagra). Niacin inogamuchirwa neU.S.Food and Drug Administration (FDA) yekushandisa iyi. Nekudaro, niacin inogona kukonzeresa "kufashaira" (kutsvuka, kuchenesa, uye kurira). Saka chimwe chigadzirwa, chinonzi niacinamide, dzimwe nguva chinosarudzwa nekuti hachikonzere mhedzisiro iyi.

Zvichida inoshanda kune ...

  • Izvo zvisina kujairika huwandu hwemafuta eropa mune vanhu vane HIV / AIDS. Kutora niacin zvinoita sekuvandudza mwero wecholesterol nemafuta eropa anonzi triglycerides mune varwere vane mamiriro aya.
  • Kurongeka kwezviratidzo zvinowedzera njodzi yeshuga, chirwere chemwoyo, uye sitiroko (metabolic syndrome). Kutora niacin kunoita kunge kunowedzera huwandu hwepamusoro-density lipoprotein (HDL kana "yakanaka") cholesterol uye kudzikisa huwandu hwemafuta eropa anonzi triglycerides mune vanhu vane metabolic syndrome. Kutora niacin pamwe neyekunyorerwa omega-3 fatty acid inoita kunge iri kushanda zvirinani.

Hazvibatsiri ...

  • Chirwere chemoyo. Yakakwira mhando tsvagiridzo inoratidza kuti niacin haidzivirire kurohwa nemoyo kana kurohwa nevanhu vanotora niacin kudzivirira kana kurapa chirwere chemwoyo. Niacin zvakare haina kuratidzirwa kudzikisa njodzi yekufa. Niacin haifanire kutorwa kurapa kana kudzivirira chirwere chemwoyo.

Husingakwani humbowo hwekuyera kushanda kwe ...

  • Kuomarara kwetsinga (atherosclerosis). Kutora niacin nemuromo pamwe nemishonga inonzi bile acid sequestrants inogona kudzikamisa kuomarara kwetsinga mune varume vane mamiriro aya. Inoita seinoshanda zvakanyanya muvarume vane huwandu hwakawanda hwemafuta eropa anonzi triglycerides. Asi kutora niacin zvinoita sekuderedza kuomarara kwetsinga muvarwere vane chirwere chinonzi peripheral arterial disease (PAD). Zvakare, niacin haidziviri zviitiko zvemoyo zvakaita sekurwadziwa kwemoyo kana sitiroko.
  • Alzheimer chirwere. Vanhu vanodya huwandu hwakawanda hwei niacin kubva kuchikafu uye multivitamini zvinoita kunge vane njodzi yakaderera yekuwana chirwere cheAlzheimer pane vanhu vanodya niacin shoma. Asi hapana humbowo hwekuti kutora niacin yekuwedzera kunobatsira kudzivirira chirwere cheAlzheimer.
  • Kurwara. Vanhu vanodya chikafu chakanyanya mu niacin vanogona kuve nemukana wakaderera wekuvandudza nyukireya. Nyukireya cataract ndiyo yakajairika mhando yekati. Mhedzisiro yekutora niacin yekuwedzera haina kuzivikanwa.
  • Utachiona hwematumbo hunokonzera manyoka (cholera). Kutora niacin nemuromo zvinoita sekuderedza manyoka muvanhu vane cholera.
  • Erectile kusagadzikana (ED). Kutora yakawedzera-kusunungurwa niacin panguva yekurara kwemasvondo gumi nemaviri zvinoita sekubatsira varume vane ED uye akakwirira lipid mazinga ekuchengetedza erection panguva yepabonde.
  • Yakakwira mazinga e phosphate muropa (hyperphosphatemia). Vanhu vane itsvo kutadza vanogona kunge vane huwandu hweropa huwandu hwephosphate. Kumwe kutsvagurudza kwekutanga kunoratidza kuti kutora niacin kunogona kudzikisa huwandu hweropa rephosphate muvanhu vane chirwere cheitsvo chekupedzisira-nhanho uye huwandu hweropa phosphate. Asi kumwe kutsvagurudza kunoratidza kuti kutora niacin hakuderedze huwandu hweropa phosphate mune vanhu vari kutorawo mishonga inoshandiswa kudzikisa ropa phosphate mazinga.
  • Kuvharika kwetsinga iri muziso (retinal vein kuvharirwa): Kutsvagurudza kwekutanga kunoratidza kuti kutora niacin kunogona kusimudzira kuona kune vanhu vane mamiriro
  • Sickle cell chirwere: Kutsvagurudza kwekutanga kunoratidza kuti kutora niacin hakuiti kuvandudza huwandu hwemafuta eropa mune vanhu vane chirwere chesero.
  • Acne.
  • Doro rinoshandisa kusagadzikana.
  • Athletic performance.
  • Kucherekedza kusakwana-kusagadzikana kwehutano (ADHD).
  • Kushungurudzika.
  • Dzungu.
  • Zvinodhaka-zvinokonzerwa nekufungidzira.
  • Migraine.
  • Kurwara kwekufamba.
  • Schizophrenia.
  • Mamwe mamiriro.
Humwe humbowo hunodiwa kuyera niacin kune izvi zvinoshandiswa.

Niacin inodhonzwa nemuviri kana ichinge yanyungudutswa mumvura uye ikatorwa nemuromo. Inoshandurwa kuita niacinamide kana ikatorwa muhuwandu hwakakura kupfuura hunodiwa nemuviri.

Niacin inodiwa kuitira mashandiro akanaka emafuta neshuga mumuviri uye kuchengetedza maseru ane hutano. Pamwero wakakwira, niacin inogona kubatsira vanhu vane chirwere chemwoyo nekuda kwemhedzisiro yayo yekuvhara. Izvo zvinogona zvakare kuvandudza mazinga eimwe mhando yemafuta anonzi triglycerides muropa.

Kushayikwa kweNiacin kunogona kukonzera mamiriro anonzi pellagra, ayo anokonzeresa kutsamwa kweganda, manyoka, uye kuora mwoyo. Pellagra yaive yakajairika mukutanga kwezana ramakumi maviri, asi haina kujairika ikozvino, nekuti zvimwe zvekudya zvine hupfu izvo zvino zvakasimbiswa neiniin. Pellagra yakave yakabviswa mutsika dzekumadokero.

Vanhu vane kudya kwakashata, kudhakwa, uye mamwe marudzi emota anononoka kukura anonzi ma carcinoid mamota anogona kunge ari panjodzi yekushomeka kweiacin. Kana ikatorwa nemuromo: Niacin ndiye ZVIMWE ZVAKANAKA kune vanhu vazhinji kana ikatorwa nemazvo. Zvigadzirwa zvemishonga zvine niacin zvakachengeteka kana zvatorwa sekurairwa. Zvine Niacin zvine zvekudya kana niacin zvinowedzera zvakachengeteka kana zvichitorwa mumadhosi akaderera kupfuura 35 mcg zuva nezuva.

Chimwe chinowanzoitika pamigumisiro ye niacin inoputika. Izvi zvinogona kukonzera kupisa, kurira, kuchenesa, uye kutsvuka kwechiso, maoko, uye chifuva, pamwe nemusoro. Kutanga nemadosi madiki eniacin uye kutora 325 mg yeaspirini pasati imwe neimwe yedosi niacin inobatsira kudzora kuyerera kwekumhanya. Kazhinji, kuita uku kunoenda apo muviri unozvijairira kumushonga. Doro rinogona kuita kuti kupisa kwemvura kuwedzere. Dzivisa yakawanda doro paunenge uchitora niacin.

Zvimwe zvidiki mhedzisiro mhedzisiro yeNiacin mudumbu kugumbuka, ura hwemukati, dzungu, kurwadziwa mumuromo, uye mamwe matambudziko.

Kana madosi eanopfuura matatu magiramu pazuva reNiacin anotorwa, zvimwe zvakakomba mhedzisiro zvinogona kuitika. Izvi zvinosanganisira matambudziko echiropa, gout, maronda emudumbu, kurasikirwa kwekuona, shuga yakakwira muropa, kurova kwemoyo zvisina kujairika, uye mamwe matambudziko akakomba.

Special matanho & yambiro:

Kubata uye kuyamwisa: Niacin ndiye ZVIMWE ZVAKANAKA yevakadzi vane pamuviri uye vanoyamwisa kana vakatorwa nemuromo muhuwandu hwakakurudzirwa. Iyo yakanyanya kukurudzirwa huwandu hwe niacin yevakadzi vane nhumbu kana vanoyamwisa ndeye 30 mg pazuva pazuva kune vakadzi vari pasi pemakore gumi nemasere ekuberekwa, uye 35 mg yevakadzi vanopfuura gumi nemasere.

Vana: Niacin ndiye ZVIMWE ZVAKANAKA painotorwa nemuromo muhuwandu hwakakurudzirwa hwezera rega rega. Asi vana vanofanirwa kudzivirira kutora dosi yeNiacin pamusoro pemiganhu yepamusoro yezuva nezuva, iri gumi mg yevana vane makore 1-3 ekuberekwa, 15 mg yevana vane makore 4-8 ekuberekwa, 20 mg yevana vane makore 9-13 ekuberekwa, uye 30 mg yevana vane makore gumi nemasere kusvika gumi nemasere ekuberekwa.

Allergies: Niacin inogona kukuvadza allergies nekukonzeresa histamine, kemikari inokonzeresa kuti maalergic zviratidzo, iburitswe.

Chirwere chemwoyo / angina asina kugadzikana: Yakawanda yakawanda niacin inogona kuwedzera njodzi yekusagadzikana kwemoyo zvisina kujairika. Shandisa nokungwarira.

Chirwere cheCrohn: Vanhu vane chirwere cheCrohn vanogona kunge vane yakaderera niacin mazinga uye vanoda kuwedzerwa panguva yekukwira-kumusoro.

Chirwere cheshuga: Niacin inogona kuwedzera shuga yeropa. Vanhu vane chirwere cheshuga vanotora niacin vanofanira kuongorora shuga yavo yeropa zvakanyatsonaka.

Gallbladder chirwere: Niacin inogona kuita kuti chirwere chenduru chiwedzere.

Gout: Yakawanda yakawanda niacin inogona kuunza pane gout.

Chirwere cheitsvo: Niacin inogona kuunganidzwa muvanhu vane chirwere cheitsvo. Izvi zvinogona kukuvadza.

Chiropa chirwere: Niacin inogona kuwedzera kukuvara kwechiropa. Usashandise huwandu hwakawanda kana uine chirwere chechiropa.

Dumbu kana ura maronda: Niacin inogona kuita kuti maronda awedzere. Usashandise huwandu hwakawanda kana uine maronda.

Yakanyanya yakaderera BP: Niacin inogona kudzikisa BP uye kuwedzera mamiriro aya.

Kuvhiya: Niacin inogona kukanganisa kudzora kweshuga yeropa panguva uye mushure mekuvhiyiwa. Rega kutora niacin kweinenge vhiki mbiri pamberi pekuvhiya kwakarongwa.

Mafuta anoisa akapoterera tendon (tendon xanthomas): Niacin inogona kuwedzera njodzi yezvirwere mu xanthomas.

Matambudziko ehutachiona: Thyroxine ihomoni inogadzirwa nehutachiona gland. Niacin inogona kudzikisa huwandu hweropa hwe thyroxine. Izvi zvinogona kuwedzera zviratidzo zvehumwe hutachiona hutachiona.

Pakati nepakati
Ive nekuchenjera nekubatanidzwa uku.
Doro (Ethanol)
Niacin inogona kukonzeresa kumenya uye kunhuwa. Kunwa doro pamwe chete neNiacin kunogona kuita kuti kumenya uye kuchenesa kuwedzere. Kune zvekare kumwe kunetsekana kuti kunwa doro neiniacin kunogona kuwedzera mukana wekukuvara kwechiropa.
Allopurinol (Zyloprim)
Allopurinol (Zyloprim) inoshandiswa kurapa gout. Kutora mibairo mikuru ye niacin kunogona kukuvadza gout uye kudzikisira kushanda kwe allopurinol (Zyloprim).
Clonidine (Catapres)
Clonidine uye niacin ese ari maviri akadzika BP. Kutora niacin neclonidine kunogona kukonzera kuwedzerwa kweropa rako kuti rinyanye kuderera.
Gemfibrozil (Lopid)
Kutora niacin pamwe negemfibrozil kunogona kukonzera kukuvara kwemhasuru mune vamwe vanhu. Shandisa nokungwarira.
Mishonga yeshuga (Antidiabetes mishonga)
Kushandiswa kwemiyero yepamusoro yeNiacin (ingangoita magiramu 3-4 zuva nezuva) inogona kuwedzera shuga yeropa. Nekuwedzera shuga yeropa, niacin inogona kudzikisira kushanda kwechirwere cheshuga. Chengetedza shuga yako yeropa zvakanyanya. Muyero wemushonga wako weshuga ungangoda kuchinjwa.

Mimwe mishonga inoshandiswa nechirwere cheshuga inosanganisira glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), metformin (Glucophage), nateglinide (Starlix), repaglinide (Prandin), chlorpropamide Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), nevamwe.
Mishonga yekukwira kweropa (Antihypertensive drug)
Kushandisa niacin nemishonga inoderedza BP inogona kuwedzera mhedzisiro yemishonga iyi uye inogona kudzikisa BP zvakanyanya.

Mimwe mishonga yekukwira kweropa inosanganisira captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), nevamwe vazhinji .
Mishonga inogona kukuvadza chiropa (Hepatotoxic zvinodhaka)
Niacin inogona kukuvadza chiropa. Yakagadziriswa-kuburitswa niacin gadziriro inoita kunge ine njodzi huru. Kutora niacin pamwe chete nemishonga inogona kukuvadza chiropa kunogona kuwedzera njodzi yekukuvara kwechiropa. Usatore niacin kana uri kutora mushonga unogona kukuvadza chiropa.

Mimwe mishonga inogona kukuvadza chiropa inosanganisira acetaminophen (Tylenol nevamwe), amiodarone (Cordarone), carbamazepine (Tegretol), isoniazid (INH), methotrexate (Rheumatrex), methyldopa (Aldomet), fluconazole (Diflucan), itraconazole (Sporaconazole). erythromycin (Erythrocin, Ilosone, vamwe), phenytoin (Dilantin), lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), nevamwe vazhinji.
Mishonga inononoka kuvhara ropa (Anticoagulant / Antiplatelet zvinodhaka)
Niacin inogona kunonoka kugwamba kweropa. Kutora niacin pamwe chete nemishonga iyo zvakare inononoka kugwamba ingangowedzera mikana yekupwanya nekubuda ropa.

Mimwe mishonga inononoka kuvhara ropa inosanganisira aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), nezvimwe.
Mishonga inoshandiswa kudzikisa cholesterol (Bile acid sequestrants)
Mimwe mishonga yekudzikisa cholesterol inonzi bile acid sequestrants inogona kudzora kuti niacin yakawanda sei inotorwa nemuviri. Izvi zvinogona kudzora kushanda kwe niacin. Tora niacin uye nemishonga ingangoita maawa mana kusvika mana parutivi.

Mimwe yemishonga iyi inoshandiswa kudzikisa cholesterol inosanganisira cholestyramine (Questran) uye colestipol (Colestid).
Mishonga inoshandiswa kudzikisa cholesterol (Statins)
Niacin inogona kukanganisa mhasuru. Mimwe mishonga inoshandiswa kudzikisa cholesterol inonzi statins inogona kukanganisa masuru. Kutora niacin pamwe chete nemishonga iyi kunogona kuwedzera njodzi yematambudziko emhasuru.

Mimwe yemishonga iyi inoshandiswa necholesterol yakakura inosanganisira rosuvastatin (Crestor), atorvastatin (Lipitor), lovastatin (Mevacor), pravastatin (Pravachol), fluvastatin (Lescol), uye simvastatin (Zocor).
Proteenecid (Benemid)
Probenecid inoshandiswa kurapa gout. Kutora mibairo mikuru ye niacin kunogona kukuvadza gout uye kudzikisira kushanda kweprobenecid.
Sulfinpyrazone (Anturane)
Sulfinpyrazone (Anturane) inoshandiswa kurapa gout. Kutora mibairo mikuru yeNiacin kunogona kukuvadza gout uye kuderedza kushanda kwesulfinpyrazone (Anturane).
Uturu hwehomoni
Muviri unongo gadzira mahormone etachiona. Niacin inogona kudzikira hutachiona hwehomoni. Kutora niacin nehutachiona hwehomoni mapiritsi kunogona kudzora mhedzisiro uye mhedzisiro yehormone yegland.
Zvishoma
Ngwarira nekubatanidzwa uku.
Aspirin
Asipurini inowanzo shandiswa ne niacin kudzikisa kumhanya kunokonzerwa ne niacin. Kutora mwero wakakwira weaspirini kunogona kudzikira kuti muviri unokurumidza sei kubvisa niacin. Izvi zvinogona kukonzera kuti kuve neinyin yakawandisa mumuviri uye pamwe inotungamira kumhedzisiro. Nekudaro, iyo yakaderera mizinga yeaspirini inowanzo shandiswa mukutsvaira kwakabatana neNiacin inoita kunge isiri dambudziko.
Nicotine chigamba (Nicoderm)
Niacin dzimwe nguva inogona kukonzera kubhururuka uye dzungu. Iyo nicotine chigamba inogona zvakare kukonzera kufuratira uye dzungu. Kutora niacin kana niacinamide uye kushandisa chikakananda chigamba kunogona kuwedzera mukana wekuti uve wakasvinwa uye uine dzungu.
Beta-carotene
Musanganiswa weNiacin nemushonga wemishonga simvastatin (Zocor) unokwidza HDL (high density lipoprotein) cholesterol ("cholesterol yakanaka") muvanhu vane chirwere chemwoyo checoronary uye yakaderera HDL mazinga. Zvisinei, kutora niacin pamwe chete nekubatanidzwa kwe antioxidants, kusanganisira beta-carotene, inoratidzika kunge inokanganisa kuwedzera uku muHDL. Hazvizivikanwe kuti izvi zvinoitika kune vanhu vasina chirwere chemwoyo checoronary.
Chromium
Kutora niacin uye chromium pamwe chete kunogona kudzikisa shuga yeropa. Kana iwe uine chirwere cheshuga uye utore chromium uye niacin zvinowedzera pamwe chete, tarisa shuga rako reropa kuti uone kuti harinyanye kudzikira.
Mishonga uye zvinowedzera izvo zvinogona kukuvadza chiropa
Niacin, kunyanya muzvikamu zvakakwirira zvinogona kukonzera kukuvara kwechiropa. Kutora niacin pamwe chete nemamwe maruva kana zvinowedzera zvinogona kukuvadza chiropa zvinogona kuwedzera njodzi iyi. Zvimwe zvezvigadzirwa izvi zvinosanganisira androstenedione, borage shizha, chaparral, comfrey, dehydroepiandrosterone (DHEA), germander, kava, mafuta epennyroyal, mbiriso tsvuku, nezvimwe.
Mishonga uye zvinowedzera izvo zvinogona kudzikisa BP
Niacin inogona kudzikisa BP. Kutora niacin nemamwe mahebhu uye zvinowedzera izvo zvakare zvinoderedza BP zvinogona kukonzera kukanganiswa kweropa kudonha zvakanyanya. Mimwe miriwo uye zvinowedzera zvinogona kudzikisa BP zvinosanganisira andrographis, casin peptides, claw yekatsi, coenzyme Q10, L-arginine, lycium, stinging nettle, theanine, nevamwe.
Mishonga uye zvinowedzera izvo zvinogona kunonoka kugwamba kweropa
Niacin inogona kunonoka kugwamba kweropa. Kushandisa niacin pamwe chete nemamwe maruva uye zvinowedzera izvo zvinononoka kuvhara ropa zvinogona kuwedzera njodzi yekubuda ropa mune vamwe vanhu. Mimwe miriwo yerudzi urwu inosanganisira angelica, clove, danshen, garlic, ginger, Panax ginseng, nezvimwe.
Kombucha tii
Iko kune kumwe kunetseka kuti kombucha tii inogona kudzora niacin kutora. Nekudaro, izvi zvinoda kudzidza zvakanyanya.
Selenium
Musanganiswa weNiacin nemushonga wemishonga simvastatin (Zocor) unokwidza HDL (high density lipoprotein) cholesterol ("cholesterol yakanaka") muvanhu vane chirwere chemwoyo checoronary uye yakaderera HDL mazinga. Zvisinei, kutora niacin pamwe chete nekubatanidzwa kwe antioxidants, kusanganisira selenium, inoratidzika kunge isinganzwisisiki kuwedzera uku muHDL. Hazvizivikanwe kuti izvi zvinoitika kune vanhu vasina chirwere chemwoyo checoronary.
Tryptophan
Imwe tryptophan kubva kuchikafu inogona kushandurwa kuita niacin mumuviri. Kutora niacin uye tryptophan pamwe chete kunogona kuwedzera mazinga uye mhedzisiro yemiiniin.
Vhitamini C
Musanganiswa weNiacin uye mushonga wekunyorerwa simvastatin (Zocor) unomutsa HDL (high density lipoprotein) cholesterol ("cholesterol yakanaka") muvanhu vane chirwere chemwoyo checoronary uye yakaderera HDL mazinga. Zvisinei, kutora niacin pamwe chete nekubatanidzwa kwe antioxidants, kusanganisira vitamini C, inoratidzika kunge isinganzwisisiki kuwedzera uku muHDL. Hazvizivikanwe kuti izvi zvinoitika kune vanhu vasina chirwere chemwoyo checoronary.
Vhitamini E
Musanganiswa weNiacin nemushonga wemishonga simvastatin (Zocor) unokwidza HDL (high density lipoprotein) cholesterol ("cholesterol yakanaka") muvanhu vane chirwere chemwoyo checoronary uye yakaderera HDL mazinga. Nekudaro, kutora niacin pamwe chete nemubatanidzwa wema antioxidants, kusanganisira vhitamini E, zvinoita sekukanganisa kumuka uku kweHDL. Hazvizivikanwe kuti izvi zvinoitika kune vanhu vasina chirwere chemwoyo checoronary.
Zingi
Mutumbi unogona kugadzira niacin. Vanhu vasina kudya zvinovaka muviri uye vane niacin kushomeka, senge vasingagone zvidhakwa, vanowedzera niacin kana vakatora zinc. Panogona kuve nenjodzi yakawedzera yemhedzisiro-inoenderana neyeniin sekukwesesa uye kuchenesa kana niacin uye zinc zvatorwa pamwechete.
Zvinwiwa zvinopisa
Niacin inogona kukonzeresa kumenya uye kuchenesa. Iyi mhedzisiro inogona kuwedzerwa kana niacin inotorwa nechinwiwa chinopisa.
Iyi inotevera doses yakadzidzwa mukutsvaga kwesainzi:

VAKURU

Nemuromo:
  • General: Zvimwe zvekudya zvekuwedzera zvigadzirwa zvinonyorwa niacin pane zvakanyorwa mune niacin zvakafanana (NE). 1 mg yeNiacin yakafanana ne1 mg NE. Kana niacin yakanyorwa pane zvakanyorwa seNE, inogona kusanganisira mamwe marudzi eniacin zvakare, kusanganisira niacinamide, inositol nicotinate, uye tryptophan. Mazuva ese anokurudzirwa mvumo yekudya (RDAs) yeNiacin muvakuru ndeye 16 mg NE yevarume, 14 mg NE yevakadzi, 18 mg NE yevakadzi vane nhumbu, uye 17 mg NE yevakadzi vanoyamwisa.
  • Kune cholesterol yakawanda: Iyo mhedzisiro yeNiacin inotarisirwa nedosi. Mitezo yeNiacin yakaderera se50 mg uye yakakwira kunge gumi nemaviri magiramu zuva rega rega yakashandiswa. Zvisinei, kuwedzera kukuru muHDL uye kuderera mu triglycerides kunoitika pa1200 kusvika 1500 mg / zuva. Migumisiro mikuru yeNiacin paLDL inoitika muna 2000 kusvika 3000 mg / zuva. Niacin inowanzo shandiswa nemimwe mishonga yekuvandudza cholesterol mazinga.
  • Yekudzivirira uye kurapa kushomeka kwevhitamini B3 uye mamiriro akafanana se pellagra: 300-1000 mg zuva nezuva muzvikamu zvakapatsanurwa.
  • Yekurapa kuomarara kwetsinga: Doses ye niacin anga akareba kunge gumi nemaviri magiramu zuva nezuva. Nekudaro, muyero weanosvika 1 kusvika ku4 magiramu eniacin zuva rega, ega kana pamwe nemastins kana bile acid sequestrants (mushonga unodzikisa cholesterol), wakashandiswa kusvika kumakore 6.2.
  • Yekuderedza kurasikirwa kwemvura kunokonzerwa nekorera toxin: 2 gramu zuva nezuva yakashandiswa.
  • Pamazinga emafuta eropa asina kujairika nekuda kwekurapwa kweHIV / AIDS: Kusvikira kumagiramu maviri zuva nezuva kwashandiswa.
  • Yechirwere chemagetsi: 2 magiramu e niacin akatorwa zuva nezuva kwemavhiki gumi nematanhatu. Mune zvimwe zviitiko, niacin 2 gramu zuva rega rega, yega kana pachiyero ichi, inotorwa pamwe ne4 magiramu emushonga omega-3 ethyl esters (Lovaza, GlaxoSmithKline Pharmaceuticals).
BY IV:
  • Yekudzivirira uye kurapa kushomeka kwevhitamini B3 uye mamiriro akafanana se pellagra: 60 mg yeNiacin yakashandiswa.
AS Pfuti:
  • Yekudzivirira uye kurapa kushomeka kwevhitamini B3 uye mamiriro akafanana se pellagra: 60 mg yeNiacin yakashandiswa.
VANA

Nemuromo:
  • General: Zvipo zvezuva nezuva zvinokurudzirwa zvekudya (RDAs) zvei niacin muvana zviri 2 mg NE yevana vacheche mwedzi 0-6, 4 mg NE yevacheche 7-12 mwedzi yezera, 6 mg NE yevana vane makore 1-3, 8 mg NE yevana makore 4-8 ekuberekwa, 12 mg NE yevana vane makore 9-13 ekuberekwa, 16 mg NE yevakomana vane makore gumi nemasere kusvika gumi nemasere, uye 14 mg NE yevasikana vane makore gumi nemasere kusvika gumi nemasere.
  • Yekudzivirira uye kurapa kushomeka kwevhitamini B3 uye mamiriro akafanana se pellagra: 100-300 mg pazuva reNiacin, yakapihwa muzvikamu zvakapatsanurwa.
3-Pyridinecarboxylic Acid, Acide Nicotinique, Acide Pyridine-Carboxylique-3, Anti-Blacktongue Factor, Antipellagra Factor, B Complex Vitamin, Complexe de Vitamines B, Facteur Anti-Pellagre, Niacina, Niacine, Nicosedine, Nicotinra Acid, Vitamini B3, Vitamin PP, Vitamina B3, Vitamine B3, Vitamine PP.

Kuti udzidze zvakawanda nezvekuti chinyorwa ichi chakanyorwa sei, ndapota ona iyo Natural Mishonga Inonzwisisika Dhatabhesi nzira.


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