Munyori: Joan Hall
Zuva Rekusika: 2 Kukadzi 2021
Gadziridza Zuva: 19 Mbudzi 2024
Anonim
Paul Kwo discusses boceprevir trial
Vhidhiyo: Paul Kwo discusses boceprevir trial

Zvemukati

Boceprevir inoshandiswa pamwe chete nemimwe mishonga miviri (ribavirin [Copegus, Rebetol] uye peginterferon alfa [Pegasys]) kurapa chirwere che hepatitis C chisingaperi (chirwere chehutachiona chichienderera mberi chinokuvadza chiropa) muvanhu vasati varapwa chirwere ichi kana avo mamiriro haana kuvandudzika pavakarapwa ne ribavirin uye peginterferon alfa chete. Boceprevir iri mukirasi yemishonga inonzi protease inhibitors. Inoshanda nekuderedza huwandu hwehutachiona hweH hepatitis C (HCV) mumuviri. Boceprevir haigone kudzivirira kupararira kwehepatitis C kune vamwe vanhu.

Boceprevir inouya sekapuleti kutora nemuromo. Inowanzo kutorwa nechikafu kana chidya chisina kujeka katatu pazuva (maawa manomwe kusvika kuma9). Tora boceprevir panguva dzakatenderedza nguva dzakafanana mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora boceprevir chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Iwe unotora peginterferon alfa uye ribavirin kwemavhiki mana usati watanga kurapwa neboceprevir. Ipapo iwe unotora mishonga yese mitatu kwemasvondo gumi nemaviri kusvika makumi mana nemana. Mushure menguva ino, iwe unozomira kutora boceprevir, asi iwe unogona kuenderera uchitora peginterferon alfa uye ribavirin kweimwezve vhiki yevhiki. Kureba kwekurapa kwako kunoenderana nemamiriro ako, kuti unopindura sei kumushonga, uye kana uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchirapa Ramba uchitora boceprevir, peginterferon alfa, uye ribavirin sekureba sekurairwa kwavanoitwa nachiremba wako. Usarega kutora chero ipi yemishonga iyi pasina kutaura nachiremba wako kunyangwe iwe uchinzwa zvakanaka.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Mishonga Inotungamira) paunotanga kurapwa neboceprevir uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.


Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora boceprevir,

  • udza chiremba wako uye wemishonga kana iwe uri weergisi kune boceprevir, chero mimwe mishonga, kana chero chinhu chinosanganiswa mumaboceprevir capsules. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako kana iwe uri kutora chero anotevera mishonga kana mishonga yemakwenzi: alfuzosin (Uroxatral); ergot mishonga yakadai se dihydroergotamine (DHE 45, Migranal), ergonovine, ergotamine (Ergomar, muCafergot, muMigergot) kana methylergonovine; cisapride (Propulsid) (haisipo muU.S.); drospirenone (mune dzimwe nzira dzekudzivirira kubata pamuviri dzakadai saBeyaz, Gianvi, Ocella, Safyral, Yasmin, Yaz, naZarah); lovastatin (Altoprev, Mevacor); mimwe mishonga yekubatwa senge carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, kana phenytoin (Dilantin); midazolam yakatorwa nemuromo; pimozide (Orap); rifampin (Rifadin, Rimactane, muIsonaRif, muRifamate, muRifater); sildenafil (chete Revatio brand inoshandiswa pachirwere chemapapu); simvastatin (Simcor, muVytorin); tadalafil (chete Adcirca brand inoshandiswa kumapapu chirwere); Wort St. kana triazolam (Halcion). Chiremba wako angangokuudza kuti usatora boceprevir kana uri kutora imwe kana yakawanda yemishonga iyi.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero yeanotevera: alprazolam (Niravam, Xanax); anticoagulants ('blood thinner') senge warfarin (Coumadin); antifungal mishonga yakadai seitraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), uye voriconazole (Vfend); atorvastatin (Lipitor, muCaduet); bosentan (Tracleer); budesonide (Pulmicort, Rhinocort, Symbicort); buprenorphine (Buprenex, Butrans, Subutex, Suboxone); calcium chiteshi blockers senge felodipine (Plendil), nicardipine (Cardene), uye nifedipine (Adalat, Afeditab, Procardia); clarithromycin (Biaxin); colchicine (Colcrys, muCol-Probenecid); cyclosporine (Gengraf, Neoral, Sandimmune); desipramine (Norpramin); dexamethasone; mimwe mishonga ye erectile dysfunction yakadai sildenafil (Viagra), tadalafil (Cialis), uye vardenafil (Levitra, Staxyn); mimwe mishonga yeHIV yakaita seatazanavir yakatorwa ne ritonavir, darunavir yakatorwa ne ritonavir, efavirenz (Sustiva, muAtripla), lopinavir yakatorwa ne ritonavir, uye ritonavir (Norvir, muKaletra); mimwe mishonga yekushaya moyo zvisina kujairika senge amiodarone (Cordarone, Pacerone), digoxin (Lanoxin), flecainide (Tambocor), propafenone (Rythmol), uye quinidine; methadone (Dolophine, Methadose); midazolam yakapihwa intravenously (kupinda mutsinga); rifabutin (Mycobutin); salmeterol (Serevent, muAdvair); sirolimus (Rapamune); tacrolimus (Prograf); uye trazodone. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana wakamboiswa chiumbwa, uye kana wakambove neropaemia (isina kukwana masero matsvuku eropa muropa kuti atakure okisijeni kune mamwe muviri), hutachiona hwehutachiona hwehutachiona hweHIV, hwakawana immunodeficiency syndrome (AIDS), chero mamiriro ezvinhu anokanganisa immune system yako, kana hepatitis B (hutachiona hutachiona hunokuvadza chiropa) kana chero rudzi rwechirwere chechiropa kunze kwehepatitis C.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora boceprevir.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kuti ungangove nepamuviri. Kana iwe uri murume, udza chiremba wako kana mumwe wako aine pamuviri, anoronga kuve nepamuviri, kana kuti anogona kuve nepamuviri. Boceprevir inofanira kutorwa ne ribavirin iyo inogona kukuvadza zvakanyanya fetus. Iwe unofanirwa kushandisa nzira mbiri dzekudzivirira kubata pamuviri iwe kana mumwe wako panguva yekurapwa nemishonga iyi uye kwemwedzi mitanhatu mushure mekurapwa. Taura nachiremba wako nezvenzira dzaunofanira kushandisa; mahormone ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, zvinodyara, mhete, kana majekiseni) zvinogona kusashanda zvakanaka mumadzimai ari kutora mishonga iyi. Iwe kana mumwe wako munofanirwa kuongororwa nhumbu mwedzi wega wega panguva yekurapwa uye kwemwedzi mitanhatu mushure mekurapwa. Kana iwe kana mumwe wako ukava nepamuviri paunenge uchitora mishonga iyi, danaidza chiremba wako nekukurumidza.
  • udza chiremba wako kana iwe uchiyamwisa.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.


Tora dosi rakarasika nechikafu nekukurumidza paunenge uchirangarira. Nekudaro, kana iri maawa maviri kana mashoma nguva yakatarwa yedosi yako inotevera, ruka iro rakarasika uye ramba uchiita yako yenguva dzose dosing chirongwa Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Boceprevir inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kusvotwa
  • kurutsa
  • manyoka
  • chinja mukugona kuravira
  • kurasikirwa nenzara
  • kuneta zvakanyanya
  • kunetseka kurara kana kuramba wakarara
  • kugumbuka
  • kurasikirwa nevhudzi
  • ganda rakaoma
  • mapundu

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • mweya wekufema
  • dzungu
  • kufenda
  • kushaya simba
  • huro, fivha, kutonhora, uye zvimwe zviratidzo zvehutachiona

Boceprevir inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Unogona kuchengeta macapuleti pane tembiricha yekamuri uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi) kwemwedzi mitatu. Iwe unogona zvakare kuchengeta macapsule mufiriji kusvikira zuva rekupera rakadhindwa pane zvakanyorwa rapfuura. Kanda chero mishonga yapera nguva kana isingachadiwe. Taura nachiremba wako nezve kuraswa kwakanaka kwemishonga yako.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari kuti aongorore mhinduro yemuviri wako kuboceprevir.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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