Munyori: Gregory Harris
Zuva Rekusika: 8 Kubvumbi 2021
Gadziridza Zuva: 21 Mbudzi 2024
Anonim
VORAXAZE® (glucarpidase) Mechanism of Action for Methotrexate Toxicity Secondary to Renal Impairment
Vhidhiyo: VORAXAZE® (glucarpidase) Mechanism of Action for Methotrexate Toxicity Secondary to Renal Impairment

Zvemukati

Glucarpidase inoshandiswa kudzivirira zvinokuvadza zve methotrexate (Rheumatrex, Trexall) kune varwere vane chirwere cheitsvo avo vari kugamuchira methotrexate yekurapa mamwe marudzi ekenza. Glucarpidase iri mukirasi yemishonga inonzi enzymes. Inoshanda nekubatsira kuputsa uye kubvisa methotrexate kubva mumuviri.

Glucarpidase inouya sehupfu hunofanira kusanganiswa nemvura uye kujowa mukati (mutsinga). Inowanzo kupihwa pamusoro pemaminitsi mashanu seyero-yenguva imwe chete. Glucarpidase inopihwa pamwe neleucovorin (mumwe mushonga unoshandiswa kudzivirira zvinokuvadza zve methotrexate) kudzamara bvunzo dze murabhoritari dzichiratidza kurapwa hakuchadiwe.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora glucarpidase,

  • udza chiremba wako uye wemishonga kana uri weergoria kune glucarpidase, chero mimwe mishonga, kana chero chinhu chinosanganiswa mujekiseni yeglucarpidase. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero einotevera: folic acid (Folicet, mune multivitamini); levoleucovorin (Fusilev); kana pemetrexed (Alimta). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • kana uri kugamuchira leucovorin, inofanira kupihwa kanenge maawa maviri pamberi kana maviri maawa mushure meglucarpidase.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora glucarpidase, fonera chiremba wako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.


Glucarpidase inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kusvotwa
  • kurutsa

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • kupindwa nechando
  • chills
  • kupuruzira kana kunzwa kupisa
  • mapundu
  • mikoko
  • kuvava
  • kuomesa kwehuro kana kunetseka kufema
  • manzwiro echiveve, kurira, kubaya, kupisa, kana kukambaira paganda
  • musoro

Glucarpidase inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune glucarpidase.


Kumbira wemishonga wako chero mibvunzo yauinayo nezveglucarpidase.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Voraxaze®
Yekupedzisira Yakagadziridzwa - 02/15/2013

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