Pembrolizumab jekiseni

Zvemukati

• Pembrolizumab jekiseni inoshandiswa: Pembrolizumab jekiseni iri mukirasi yemishonga inonzi monoclonal antibodies. Inoshanda nekubatsira immune system yako kudzora kana kumisa kukura kwemasero ekenza.
• Usati wagamuchira pembrolizumab jekiseni,
• Pembrolizumab jekiseni inogona kukonzeresa mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Pembrolizumab jekiseni inoshandiswa: Pembrolizumab jekiseni iri mukirasi yemishonga inonzi monoclonal antibodies. Inoshanda nekubatsira immune system yako kudzora kana kumisa kukura kwemasero ekenza.

• kurapa melanoma (rudzi rwegomarara reganda) iyo isingakwanise kurapwa nekuvhiyiwa kana yakapararira kune zvimwe zvikamu zvemuviri, kana pamwe nemimwe mishonga yekemotherapy yekurapa nekudzivirira kudzoka kwemelanoma mushure mekuvhiyiwa kuti ibvise iyo uye chero lymph inokanganiswa. mapfundo;
• kurapa mamwe marudzi easina-madiki-maseru kenza yemapapu (NSCLC) isingakwanise kurapwa nekuvhiyiwa, mamwe makemikari ekurapa mishonga, kana radiation radiation kana iyo yakapararira kune zvimwe zvikamu zvemuviri kana kuwedzera munguva kana mushure mekurapwa neplatinum ine chemotherapy mishonga (cisplatin, carboplatin), kana musanganiswa nemamwe mishonga yemakemikari (paclitaxel, pemetrexed) kurapa mamwe marudzi eNSCLC akapararira kune dzimwe nhengo dzemuviri;
• kurapa imwe mhando yemusoro nekenza yemutsipa iyo inoramba ichidzoka kana yakapararira kune dzimwe nhengo dzemuviri uye isingakwanise kubviswa nekuvhiyiwa. Inogona zvakare kushandiswa musanganiswa ne fluorouracil uye platinum ine chemotherapy mishonga (cisplatin, carboplatin) kurapa imwe mhando yemusoro nekenza yemutsipa inoramba ichidzoka kana yakapararira kune dzimwe nhengo dzemuviri uye isingakwanise kurapwa nekuvhiyiwa. Pembrolizumab inoshandiswawo kurapa imwe mhando yemusoro nekenza yemutsipa iyo yawedzera kana kupararira kune zvimwe zvikamu zvemuviri panguva kana mushure mekurapwa nemakemikari mishonga;
• kurapa imwe mhando yeHodgkin's lymphoma (Hodgkin's chirwere) muvana nevakuru vasina kuita zvirinani nemamwe makemikari ekurapa kana kuve nani asi vakadzoka mushure mekurapwa nemamwe mishonga yemakemikari uye muvana mushure mekurapwa kaviri kana kupfuura nguva nemamwe mishonga yemakemikari. ;
• kurapa rwumwe rudzi rwepakati pemastastinal B-cell lymphoma (PMBCL; isiri-Hodgkin lymphoma) muvana nevakuru vasina kuita zvirinani nemamwe makemikari ekurapa kana kudzoka mushure mekurapwa kaviri kana kupfuura nguva nemimwe mishonga yekemotherapy;
• kurapa imwe mhando yekenza yeurothelial (kenza yemubhedha wedundira uye zvimwe zvikamu zveweti) iyo yakapararira kumatishu ari pedyo kana zvimwe zvikamu zvemuviri kuvanhu vasingakwanise kugamuchira platinamu ine chemotherapy mishonga (cisplatin, carboplatin) , kana ane kenza yakawedzera panguva kana mushure mekurapwa neiyi chemotherapy mishonga;
• kurapa imwe mhando yekenza yedundira mune vanhu vasina kuzopora nemumwe mushonga (Bacillus Calmette-Guerin; BCG therapy) uye vasingakwanise kana vakasarudza kusarapwa nekuvhiyiwa kubvisa dundira;
• kurapa mamwe marudzi ekenza yakajeka (kenza inotangira muura hukuru) uye mamwe marudzi emota yakasimba senzira yekutanga kurapwa muvana nevakuru isingakwanise kurapwa nekuvhiya kana yakapararira kune zvimwe zvikamu zvemuviri kana mune izvo yakawedzera mushure mekurapwa nemamwe mishonga yekemotherapy;
• kurapa mamwe marudzi ekenza yemudumbu (gomarara remudumbu) kana gomarara riri munzvimbo inosangana nedumbu (iyo chubhu iri pakati pehuro nedumbu) yadzoka kana yakapararira kune dzimwe nhengo dzemuviri panguva kana mushure 2 kana akawanda ekurapa chemotherapy;
• kurapa imwe mhando yekenza yesophageal iyo yadzoka uye yapararira kumatishu ari pedyo kana zvimwe zvikamu zvemuviri mushure mekurapwa neimwe kana mimwe mishonga yemakemikari uye haigone kurapwa nekuvhiya kana radiation radiation;
• kurapa mamwe marudzi egomarara remuromo wechibereko (gomarara rinotanga mukuvhurika kwechibereko [chibereko] iro rakadzoka kana rapararira kune dzimwe nhengo dzemuviri panguva kana mushure mekurapwa nemumwe mushonga wechemaotherapy;
• kurapa mamwe marudzi ehepatocellular carcinoma (HCC; rudzi rwegomarara rechiropa) muvanhu vakamborapwa zvisina kubudirira nesorafenib (Nexafar);
• kurapa Merkel cell carcinoma (MCC; rudzi rwegomarara reganda) muvana nevakuru rakadzoka ndokupararira kumatishu ari pedyo kana zvimwe zvikamu zvemuviri;
• mukubatana ne axitinib (Inlyta) kurapa yakakwira renal cell carcinoma (RCC; mhando yekenza inotanga muitsvo);
• mukubatana nelenvatinib (Lenvima) kurapa imwe mhando yekenza ye endometrium (lining yechibereko) iyo yakapararira kune mamwe mativi emuviri kana kuwedzerwa panguva kana mushure mekurapwa nemishonga yekemotherapy kana isingakwanise kurapwa nekuvhiya kana radiation. kurapa;
• kurapa mamwe marudzi emamota akasimba akapararira kune dzimwe nhengo dzomuviri kana asingakwanise kurapwa nekuvhiya muvakuru nevana avo vakamborapwa vasina kubudirira nemumwe mushonga wemakemikari uye vasina dzimwe nzira dzinogutsa dzekurapa;
• kurapa mamwe marudzi eaccumous squamous cell carcinoma (CSCC; gomarara reganda) iro rakadzoka kana rapararira kune dzimwe nhengo dzemuviri uye risingakwanise kurapwa nekuvhiya kana radiation radiation;
• uye pamwe chete nekemotherapy kurapa imwe mhando yekenza yemazamu yakadzokera kumatishu ari padyo kana yakapararira kune dzimwe nhengo dzemuviri uye isingakwanise kurapwa nekuvhiya.

Pembrolizumab jekiseni rinouya sehupfu hunosanganiswa nemvura uye kujowa mukati (mutsinga) pamusoro pemaminitsi makumi matatu nachiremba kana mukoti muchipatara kana nzvimbo yekurapa. Inowanzojowa kamwe chete pa3 kana matanhatu mavhiki chero bedzi chiremba wako achikurudzira kuti ugamuchire kurapwa.

Pembrolizumab jekiseni inogona kukonzeresa kuita kwakakomba panguva, kana nguva pfupi mushure mekumisikidzwa kwemushonga. Kana ukasangana nechimwe chezviratidzo zvinotevera, udza chiremba wako nekukasira: kupukuta, kupisa muviri, kutonhora, kubvunda, dzungu, kunzwa kupera simba, kufema kwekufema, kunetseka kufema, kuchenesa, mapundu, kana mikoko.

Chiremba wako anogona kunonoka kana kumisa kurapwa kwako nepembrolizumab jekiseni, kana kukubata iwe nemimwe mishonga, zvinoenderana nemhinduro yako kumushonga uye chero mhedzisiro yaunosangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa nepembrolizumab jekiseni uye pese paunogamuchira dosi. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati wagamuchira pembrolizumab jekiseni,

• udza chiremba wako uye wemishonga kana uri weergoria kune pembrolizumab, chero mimwe mishonga, kana chero chinhu chinosanganiswa mupembrolizumab jekiseni. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe wakambove neinhengo kana pfupa rekutsvaira uye kana iwe uine kana wakambove nemwaranzi yekurapa kuchipfuva chako nzvimbo; chirwere chinodzivirira muviri (mamiriro umo immune system inorwisa chikamu chine hutano chemuviri) senge chirwere cheCrohn (mamiriro umo immune system inorwisa kumisikidza kwenzira yekugaya inokonzeresa kurwadziwa, manyoka, kuonda, uye fivhiri), ulcerative colitis (mamiriro anokonzera kuzvimba uye maronda mumucheto wekoloni [ura hukuru] uye rectum), kana lupus (mamiriro umo immune system inorwisa matishu mazhinji uye nhengo dzinosanganisira ganda, majoini, ropa, neitsvo); chirwere cheshuga; zvinetso zvetachiona; chero mhando yemapapu chirwere kana matambudziko ekufema; kana hosha yeitsvo kana yechiropa.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe uchafanirwa kutora bvunzo yepamuviri usati watanga kurapwa. Iwe haufanire kuve nepamuviri iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchitwa. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri iwe uchinge uchigamuchira pembrolizumab jekiseni, fonera chiremba wako nekukasira. Pembrolizumab jekiseni inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa kana kuronga kuyamwisa. Chiremba wako anogona kukuudza kuti usamwisa mwana uchigamuchira pembrolizumab jekiseni, uye kwemwedzi mina mushure medosi yako yekupedzisira.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Pembrolizumab jekiseni inogona kukonzeresa mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kubatana kana kurwadziwa musana
• kuzvimba kwemuviri kana kumeso
• shanduko paganda reganda
• kuneta zvakanyanya kana kushaya simba
• kupindwa nechando
• kusvotwa
• kurutsa

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• blisters kana kubvisa ganda; kutsvuka kweganda; mapundu; kana kuvava
• maronda anorwadza kana maronda mumuromo, mhuno, huro, kana nzvimbo yekubereka
• mweya wekufema
• kurwadziwa pachipfuva
• chitsva kana kuwedzera kukosora
• manyoka
• zvituru zvakasviba, zvinonoka, zvinonamira, kana zvine ropa kana mamasi
• kurwadziwa kwakanyanya mudumbu
• kusvotwa kwakanyanya uye kurutsa
• yakawedzera kana kudzikira chishuwo
• kuwedzera nyota
• kurwadziwa kumusoro kwepamusoro chikamu chedumbu
• yero yeganda kana maziso
• kubuda ropa nyore kana kupwanya
• kukurumidza kurova kwemoyo
• shanduko mukurema (kuwana kana kurasikirwa)
• kurasikirwa nevhudzi
• kuwedzera kudikitira
• kunzwa kutonhora
• kudzika kwezwi kana kutinhira
• kuzvimba pamberi pemutsipa (goiter)
• kurira uye kushaya simba mutsoka, makumbo, maoko nemaoko
• yakanyanya kana inoramba ichirwadza musoro, tsandanyama aches
• kushaya simba kwakanyanya kwemhasuru
• dzungu kana hurema
• kufenda
• shanduko muhuwandu kana ruvara rweweti
• kurwadziwa kana kutsva uku uchiita weti
• ropa mune weti
• shanduko pane zvakaratidzwa
• kunzwa kunetseka

Pembrolizumab jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari kuti atarise mhinduro yemuviri wako kujekiseni repembrolizumab. Kune mamwe mamiriro, chiremba wako anozoraira bvunzo bvunzo usati watanga kurapwa kwako kuti uone kana kenza yako inogona kurapwa ne pembrolizumab.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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