Olaparib

Zvemukati

• Usati watora olaparib,
• Olaparib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

Mahwendefa eOlaparib anoshandiswa kubatsira kuchengetedza kupindurwa kwemamwe marudzi eovarian (nhengo dzekubereka dzevakadzi panogadzirwa mazai), fallopian tube (chubhu inotakura mazai akaburitswa nemazai kuenda muchibereko), uye peritoneal (rukoko rwechitunha chinoisa mudumbu ) kenza mune vanhu vakapindura zvakakwana kana kupindura zvishoma kune yavo yekutanga kana yekupedzisira chemotherapy kurapwa. Mahwendefa eOlaparib anoshandiswa zvakare kurapa mamwe marudzi ekenza yemazamu ayo akapararira kune dzimwe nhengo dzemuviri uye asina kuvandudzika kana kuwanda mushure mekurapwa nemamwe marapirwo. Mahwendefa eOlaparib anoshandiswa zvakare kurapa imwe mhando yekenza yeprostate yakapararira kune zvimwe zvikamu zvemuviri, haichapindure kurapwa kana kuvhiya kudzikisa testosterone mazinga, uye yafambira mberi mushure mekurapwa ne enzalutamide (Xtandi) kana abiraterone (Yonsa , Zytiga). Mahwendefa eOlaparib uye macapsule anoshandiswa zvakare kurapa kenza yeovari iyo isina kuvandudzika kana kuwedzera huremu mushure mekurapwa nemamwe marapirwo matatu. Mahwendefa eOlaparib anoshandiswa zvakare kubatsira kuchengetedza mhinduro yeimwe mhando yekenza yepancreatic iyo isina kupararira kana kufambira mberi mushure mekutanga chemotherapy kurapwa. Olaparib ndeye polyadenosine 5'-diphosphoribose polymerase (PARP) enzyme inhibitor. Inoshanda nekuuraya cancer maseru.

Olaparib inouya sehwendefa kana kapuleti kutora nemuromo kaviri pazuva kana kana pasina chikafu. Edza kuisa nzvimbo yako madhora anenge gumi nemaviri akaparadzaniswa. Tora olaparib panguva dzakatenderedza nguva dzakafanana mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora olaparib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza iyo piritsi kana capsule yakazara; usapwanya kutsenga, kupatsanura, kana kuzvipwanya.

Olaparib inowanikwa sehwendefa uye sekapisi. Mahwendefa uye makaputa ane zviyero zvakasiyana zveolaparib uye haafanire kuchinjaniswa. Taura nachiremba wako kana wemishonga kana iwe uine chero mibvunzo nezve iyo piritsi uye capsule gadziriro.

Chiremba wako anogona kudzikisira yako olaparib kana kukuudza kuti umise kutora olaparib kwenguva yakati pakurapwa kwako. Izvi zvinoenderana nekuti mushonga unoshanda sei kwauri uye chero mhedzisiro yaungasangana nayo. Ive neshuwa yekuudza chiremba wako kuti unonzwa sei panguva yekurapa kwako na olaparib.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Gwaro RezveMishonga) paunotanga kurapwa neolaparib. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kuti utore Gwaro reMishonga.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora olaparib,

• udza chiremba wako uye wemishonga kana uri weergoria kune olaparib, chero mimwe mishonga, kana chero chinhu chinowanikwa mumatafura eolaparib kana macapsule. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: maantibayoti akadai ciprofloxacin (Cipro), clarithromycin (Biaxin, muPrevpac), erythromycin (EES, Erythrocin, vamwe), nafcillin, uye telithromycin (haisisipo muU.S., Ketek); antifungals senge fluconazole (Diflucan), itraconazole (Onmel, Sporanox), ketoconazole (Extina, Nizoral, Xolegel), posaconazole (Noxafil), uye voriconazole (Vfend); aprepitant (Simbisa); mimwe mishonga yekurapa kubatwa kwakadai sa carbamazepine (Carbatrol, Epitol, Tegretol, Teril), uye phenytoin (Dilantin, Phenytek); bosentan (Tracleer); crizotinib (Xalkori); diltiazem (Cardizem, Cartia, Tiazac, nevamwe); mimwe mishonga yekurapa hepatitis C yakadai seboceprevir (haichawanikwi muU.S., Victrelis) uye telaprevir (haichawanikwi muU.S., Incivek); mimwe mishonga yekurapa hutachiona hwehutachiona hwehutachiona hweHIV (HIV) kana kuwana immunodeficiency syndrome (AIDS) senge amprenavir (haisisipo muUS, Agenerase), atazanavir (Reyataz, muEvotaz), darunavir (Prezista), efavirenz (Sustiva, muAtripla) , etravirine (Intelence), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir / ritonavir (Kaletra), nelfinavir (Viracept), ritonavir (Norvir, muKaletra), uye saquinavir (Invirase); imatinib (Gleevec); modafinil (Provigil); nefazodone; imwe chemotherapy mishonga yekenza, rifampin (Rifadin, Rimactane, muRifamate, muRifater), uye verapamil (Calan, Verelan, muTarka). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort. Iwe haufanire kutora wort St. John paunenge uchitora olaparib.
• udza chiremba wako kana iwe kana wakambove nemapapu kana kufema matambudziko, kana itsvo kana chiropa chirwere.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kuronga kubereka mwana. Ungangoda kuita bvunzo yepamuviri usati watanga kurapwa, Haufanire kuve nepamuviri paunenge uchitora olaparib. Iwe unofanirwa kushandisa anoshanda ekuberekwa kudzivirira kudzivirira kubata panguva yekurapa kwako na olaparib uye kweinenge mwedzi mitanhatu mushure mekupedzisira kwako dosi. Kana iwe uri murume uye mumwe wako anogona kuve nepamuviri, iwe unofanirwa kushandisa zvinobudirira kudzora kubereka panguva yekurapa kwako olaparib mahwendefa uye kwemwedzi mitatu mushure mekupedzisira kwako dosi. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri uchitora olaparib, dana chiremba wako nekukurumidza. Olaparib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Usamwisa mwana paunenge uchitora olaparib uye kwemwedzi mumwe mushure mekupedzisira kwako.
• iwe unofanirwa kuziva kuti haufanire kupa urume paunenge uchitora mapiritsi eolaparib uye kwemwedzi mitatu mushure mekupedzisira kwako.

Usadye grapefruit kana maorenji eSeville (dzimwe nguva anoshandiswa mumarmalade), kana kunwa muto wemazambiringa kana jisi reSeville orenji uchitora mushonga uyu.

Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Olaparib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kusvotwa
• kurutsa
• manyoka
• kuvimbiswa
• chirungurira
• musoro
• kuderera kwechido
• mhasuru, kubatana, kana kurwadziwa musana
• kuneta
• kurwadziwa nemudumbu kana kusagadzikana
• kuravira shanduko
• kurwadziwa mumuromo kana maronda
• kushushikana
• kuora mwoyo
• ganda rakaoma
• kuvava
• mapundu
• kunetseka kurara kana kuramba wakarara
• kurwadziwa weti

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

• fivha, kufema kwekufema, kukosora, kana kufema
• mweya wekufema
• kushaya simba
• kuneta zvakanyanya
• kuonda
• kupwanya kusingawanzo kana kubuda ropa
• ganda rakachenuruka
• ropa mune weti kana chigaro
• fivha, kutonhora, kukosora, kurwadziwa pahuro, kana zvimwe zviratidzo zvehutachiona
• kurwadziwa, unyoro, kutsvuka, kana kuzvimba mune rimwe gumbo
• kurwadziwa kwepfupa kana kusimba; mweya wekufema; kukosora ropa; kana kufema nekukurumidza

Olaparib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo runowanikwawo pamhepo pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira bvunzo bvunzo usati watanga kurapwa kwako kuti uone kana mamiriro ako achigona kurapwa neolaparib. Chiremba wako anozoraira kumwe kuongorora kwelebhu panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kuna olaparib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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