Osimertinib

Zvemukati

• Usati watora osimertinib,
• Osimertinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Osimertinib inoshandiswa kubatsira kudzivirira imwe mhando yeasina-madiki maseru kenza yemapapu (NSCLC) kubva kudzoka mushure mekunge bundu (s) rabviswa nekuvhiyiwa muvakuru. Iyo inoshandiswawo sekutanga kurapwa kweimwe mhando yeNSCLC iyo yakapararira kune dzimwe nhengo dzomuviri muvanhu vakuru. Osimertinib inoshandiswawo kurapa mamwe marudzi eNSCLC ayo akapararira kune zvimwe zvikamu zvemuviri kuvanhu vakuru vasingakwanise kurapwa zvinobudirira nemamwe mishonga yakafanana yekemotherapy. Osimertinib ari mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kumisa kana kunonoka kupararira kwekenza maseru uye zvinogona kubatsira kudzikira mamota.

Osimertinib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kamwe pazuva. Kureba kwekurapa kwako kunoenderana nekuti mushonga uyu unoshanda sei kwauri, uye nemhedzisiro iwe yaunowana. Tora osimertinib panguva dzakatenderedza zuva rimwe nerimwe. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora osimertinib chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Kana iwe usingakwanise kumedza mahwendefa, isa iyo piritsi mumatafura mana (2 oz [60 mL]) emvura uye fambisa kusvikira hwendefa iri zvidimbu zvidiki. Imwai musanganiswa ipapo. Dururira mune imwe hafu yekapu (4 oz [120 mL]) kune kapu yemvura (8 oz [240 mL]) kune mudziyo wawakashandisa, sukurudza, uye kunwa kuti uve nechokwadi chekuti wawana muyero wakazara weosimertinib. Usashandise mvura ine kabhoni kana chero imwe yemvura kuputsa iyo osimertinib piritsi. Usapwanya piritsi kana kupisa musanganiswa. Kana iwe uine nasogastric (NG) chubhu, chiremba wako kana wemishonga anotsanangura kuti ungapa sei musanganiswa uyu kuburikidza neNG tube.

Chiremba wako anogona kumbomira kurapwa kwenguva pfupi kana zvachose kana kudzikisa dosi yako osimertinib zvichienderana nemhedzisiro yaunosangana nayo. Ive neshuwa yekutaura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Usarega kutora osimertinib usina kutaura nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora osimertinib,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune osimertinib, chero mimwe mishonga, kana chero chimwe chezvinhu zviri muhwendefa reosimertinib. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera zvinovaka muviri zvauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: anagrelide (Agrylin); arsenic trioxide (Trisenox); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); chloroquine (Aralen); chlorpromazine; cilostazol (Pletal); citalopram (Celexa); donepezil (Aricept); escitalopram (Lexapro); haloperidol (Haldol); mishonga yemwoyo kana yeropa; methadone (Dolophine, Methadose); oxaliplatin (Eloxatin); phenytoin (Dilantin, Phenytek); pimozide (Orap); quinidine (muNuedexta); rifampin (Rifadin, Rimactane, muRifamate, Rifater); rosuvastatin (Crestor); sulfasalazine (Azulfidine); thioridazine; topotecan (Hycamtin); uye vandetanib (Caprelsa). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kusangana ne osimertinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.Chiremba wako angangokuudza kuti usatora St. John's wort uchitora osimertinib.
• udza chiremba wako kana iwe kana wakambove nerefu QT syndrome (mamiriro anowedzera mukana wekubata kurova kwemoyo zvisina kujairika uko kunogona kukonzera kupera simba kana kufa kamwe kamwe); kurova kwemoyo zvisina kujairika; kukundikana kwemoyo (mamiriro umo moyo usingakwanise kupomba ropa rakakwana kune mamwe mativi emuviri); yakakwira kana kudzikira pane zvakajairwa mazinga esodium, potasium, calcium, kana magnesium muropa rako; matambudziko eziso; kana mamwe mamiriro emapapu.
• iwe unofanirwa kuziva kuti osimertinib inogona kudzora kubereka muvarume nevakadzi. Nekudaro, iwe haufanire kufunga kuti iwe kana mumwe wako haugone kuve nepamuviri. Udza chiremba wako kana iwe uri nepamuviri, kana kuronga kuva nepamuviri. Iwe unozofanirwa kutora kutora nhumbu usati watanga kurapwa uye haufanire kuve nepamuviri paunenge uchitora osimertinib. Shandisa zvinobudirira kuberekwa panguva yekurapa kwako neosimertinib, uye kwemavhiki matanhatu mushure mekupedzisira kwedosi. Kana iwe uri murume uye mumwe wako achigona kuve nepamuviri, iwe unofanirwa kushandisa anoshanda ekudzivirira kubereka panguva yekurapa kwako uye kwemwedzi mina mushure meiyo dosi yekupedzisira. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe kana mumwe wako mukava nepamuviri muchitora osimertinib, danai chiremba wako nekukasira. Osimertinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Chiremba wako anogona kukuudza kuti usayamwisa panguva yekurapa kwako uye kwemavhiki maviri mushure mekupedzisira dosi.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatora dose kunonoka kana kutora dhiviri dhizaini kugadzira iyo yakarasika imwe.

Osimertinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• manyoka
• kuvimbiswa
• mapundu
• kuvava
• ganda rakaoma kana rinotsemuka
• eczema
• kusvotwa
• kurutsa
• kurasikirwa nenzara
• kuzvimba kana maronda mumuromo
• kurwadziwa shure
• nzara shanduko dzinosanganisira kuzvimba, kutsvuka, kurwadziwa, kutsemuka, kutyoka, uye kupatsanura kana kurasikirwa kubva kune mbambo

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kutsanya, kana kurova kurova kwemoyo; mweya wekufema; kuzvimba kwemakumbo kana tsoka, kana kunzwa musoro wakareruka
• kupindwa nechando; kutsva kana kuwedzera kufema kwekufema; kunetseka kufema, kana kukosora
• ganda rinobuda kana kubvarura
• mavara epepuru, kutsvuka, kana mikoko pamaoko, makumbo ezasi, kana magaro
• kurwadziwa pachipfuva
• kuneta zvakanyanya
• kuzvimba, kutsvuka, kusvimha kana kurwadza maziso; kunzwisisika kuchiedza; kana maonero anochinja

Osimertinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira mimwe miedzo yebasa remoyo usati uye panguva yekurapa kwako kuve nechokwadi kuti zvakachengeteka kuti iwe utore osimertinib, uye kutarisa mhinduro yemuviri wako kumushonga. Chiremba wako anogona zvakare kuraira bvunzo bvunzo usati watanga kurapwa kwako kuti uone kana kenza yako inogona kurapwa ne osimertinib.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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