Ribociclib

Zvemukati

• Usati watora ribociclib,
• Ribociclib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

Ribociclib inoshandiswa pamwe chete nemumwe mushonga kurapa imwe mhando yehormone receptor-inovhenekera (zvinoenderana nemahormone akadai seestrogen kukura) kenza yemazamu yepamusoro kana iyo yakapararira kune zvimwe zvikamu zvemuviri muvakadzi vasina kumbosangana nekuguma. yehupenyu; kupera kwemwedzi yekuenda kumwedzi) uye mune avo vari padhuze kana vakatove nekuona kumwedzi. Ribociclib inoshandiswawo pamwe chete nefulvestrant (Faslodex) kurapa imwe mhando yehormone receptor-inovhenekera kenza yemazamu kana yakapararira kune dzimwe nhengo dzemuviri sekutanga kurapwa kana kune vanhu vasina kurapwa zvinobudirira nemamwe marapirwo mumadzimai akatoona kuenda kumwedzi. Ribociclib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kudzora kana kumisa kupararira kwekenza maseru.

Ribociclib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kamwe zuva nezuva mangwanani kwemazuva ekutanga makumi maviri nemasere ezuva makumi maviri nemasere ezuva. Tora ribociclib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora ribociclib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya. Usatore mapiritsi akatyoka kana akapwanyika.

Kana iwe ukarutsa mushure mekutora ribociclib, usatore imwe dosi. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako anogona kudzikisira muyero wako we ribociclib kana zvachose kana kumbomira kurapwa. Izvi zvinoenderana nekuti mushonga unoshanda sei kwauri uye nemhedzisiro iwe yaunosangana nayo. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako ne ribociclib.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora ribociclib,

• udza chiremba wako uye wemishonga kana iwe uri weergiziki kune ribociclib, chero mimwe mishonga, kana chero chipi zvacho chemapiritsi e ribociclib. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: amiodarone (Nexterone, Pacerone); mamwe maantibhakitiriya akadai secacithromycin (Biaxin, mu Prevpac), erythromycin (EES, Ery-tab, Eryped), uye moxifloxacin (Avelox); mamwe antifungal mishonga senge itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), uye voriconazole (Vfend); bepridil (haichawanikwi muU.S.); boceprevir (Victrelis, haichawanikwi muU.S.); chloroquine (Aralen); conivaptan; cyclosporine (Gengraf, Neoral, Sandimmune); dihydroergotamine (DHHE 45, Migranal); disopyramide (Norpace); ergotamine (Ergomar, muCafergot, muMigergot); everolimus (Afinitor, Zortress); fentanyl (Abstral, Actiq, Fentora, Onsolis); halofantrine (Halfan; haichawanikwi muU.S.); haloperidol (Haldol); mimwe mishonga yehutachiona hwehutachiwana hwevanhu (HIV) se efavirenz (Sustiva, muAtripla), indinavir (Crixivan), lopinavir (muKaletra), nelfinavir (Viracept), ritonavir (Norvir, muKaletra), uye saquinavir (Invirase); mimwe mishonga yekubatwa kwakadai sa carbamazepine (Carbatrol, Equetro, Teril, vamwe) uye phenytoin (Dilantin, Phenytek); methadone (Dolophine, Methadose); nefazodone; ondansetron (intravenous); pimozide (Orap); procainamide; quinidine (muNuedexta); rifampin (Rimactane, Rifadin, muRifamate, muRifater); sirolimus (Rapamune); sotalol (Betapace, Sotylize); tacrolimus (Envarsus XR, Prograf), uye tamoxifen (Soltamox). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.Mimwe mishonga yakawanda inogona zvakare kubatana ne ribociclib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's Wort.
• udza chiremba wako kana iwe uchangobva kuve nekurwadziwa kwemoyo; kana kuve kana kuve wakamboita moyo unononoka; nguva yakareba yeQT (chinetso chemoyo chisingawanzo chinogona kukonzera kurova kwemoyo zvisina kujairika, kufenda, kana kufa kamwe kamwe); asina kujairika mazinga e potassium, calcium, phosphorus, kana magnesium muropa rako; kutadza kwemoyo; kana chiropa, itsvo, kana chirwere chemwoyo.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe unozofanirwa kutora kutora nhumbu usati watanga kurapwa. Shandisa nzira yakavimbika yekudzivirira kuberekwa kudzivirira kubata pamuviri panguva yekurapa kwako uye kwemavhiki matatu mushure mekuita kwako kwekupedzisira. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri uchitora ribociclib, dana chiremba wako pakarepo. Ribociclib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa kana kuronga kuyamwisa. Iwe haufanire kuyamwa uchi tora ribociclib uye kweanenge mavhiki matatu mushure mekuita kwako kwekupedzisira.
• iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume. Taura nachiremba wako nezve njodzi dzekutora ribociclib.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora ribociclib.

Usadye grapefruit kana kunwa mazambiringa paunenge uchinwa mushonga uyu.

Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Ribociclib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• manyoka
• kuvimbiswa
• kurwadziwa nemudumbu
• musoro
• kurasikirwa nevhudzi
• kurwadziwa shure
• kuvava
• maronda emuromo
• kuzvimba kwemaoko, tsoka, makumbo, kana makumbo ezasi
• kunetseka kurara kana kuramba wakarara

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

• fivha, huro, chironda, kana zvimwe zviratidzo zvehutachiona
• mapundu
• kuputika kana kubvisa ganda
• kupisa kana kutuka kwemiromo, maziso, kana muromo
• inokurumidza, isina kujairika, kana kurova kurova kwemoyo
• kunetseka kufema kana kupfupika kwekufema; kukosora pamwe kana pasina mhuno; kana kurwadziwa muchipfuva
• dzungu
• kufenda
• yero yeganda kana maziso
• yakasviba kana shava (yeti-yeruvara) weti
• kuneta
• kurasikirwa nenzara
• kurwadziwa kumusoro kwekurudyi kwedumbu
• kusvotwa
• kurutsa
• kubuda ropa kana kupwanya zviri nyore kupfuura zvakajairwa

Ribociclib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari ekuongorora usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune ribociclib. Chiremba wako anogona zvakare kuraira electrocardiogram (ECG; bvunzo inoyera chiitiko chemagetsi mumoyo) usati uye panguva yekurapa kwako.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Kisqali^®

• Kisqali^® Femera^® (semubatanidzwa chigadzirwa chine Letrazole uye Ribociclib)