Nusinersen jekiseni

Zvemukati

• Usati watora jekiseni re nusinersen,
• Nusinersen jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

Nusinersen jekiseni rinoshandiswa pakurapa kwepasipera tsandanyama atrophy (chinogarwa nhaka chinoderedza tsandanyama simba uye kufamba) muvacheche, vana, uye vakuru. Nusinersen jekiseni iri mukirasi yemishonga inonzi antisense oligonucleotide inhibitors. Inoshanda nekuwedzera huwandu hweimwe puroteni inodiwa kuti mhasuru uye tsinga dzishande zvakajairika.

Jekiseni reNusinersen rinouya semhinduro (mvura) kujekesa intrathecally (munzvimbo inozadzwa nemvura yemupendero). Jekiseni raNusinersen rinopihwa nachiremba muhofisi yezvokurapa kana kukiriniki. Iyo inowanzo kupihwa se4 ekutanga madhizaini (kamwe chete pavhiki mbiri kwekutanga matatu madhizaini uye zvakare mazuva makumi matatu mushure meiyo yechitatu dosi) uyezve ndokupihwa kamwe chete pamwedzi mina mushure.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora jekiseni re nusinersen,

• udza chiremba wako uye wemishonga kana uri weergoria kune nusinersen, chero mimwe mishonga, kana chero chinhu chinosanganiswa mujekiseni re nusinersen. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe kana wakambove nechirwere cheitsvo.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchigamuchira nusinersen jekiseni, fonera chiremba wako.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikugamuchira jekiseni re nusinersen.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Ukasuwa musangano kuti ugamuchire jekiseni re nusinersen, fonera chiremba wako ipapo ipapo kuti urongezve nguva yako. Chiremba wako anogona kukuudza kuti utangezve yako yepamberi chirongwa kuti ugamuchire nusinersen jekiseni, uine angangoita mazuva gumi nemana pakati peya4 ekutanga madhizaizi uye nemwedzi mina pakati peanotevera madosi.

Nusinersen jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kuvimbiswa
• gasi
• kuonda
• musoro
• kurutsa
• kurwadziwa shure
• kudonha
• inomhanya kana yakanyongedzwa mhino, kuhotsira, kurwadziwa pahuro
• nzeve kurwadziwa, fivha, kana zvimwe zviratidzo zvehutachiona hutachiona
• kupindwa nechando

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

• kubuda ropa zvisina kujairika kana kupwanya
• kuderera kwekuita weti; furo, pingi, kana shava weti weti; kuzvimba mumaoko, kumeso, tsoka kana dumbu
• kazhinji, zvinokurumidza, zvakaoma, kana zvinorwadza kuita weti
• kukosora, kufema kwekufema, fivha, kutonhora

Jekiseni reNusinersen rinogona kudzora kukura kwemucheche. Chiremba wemwana wako anozotarisa kukura kwake zvakanaka. Taura nachiremba wemwana wako kana iwe uine zvinetsekana nezve kukura kwemwana wako iye achiwana mushonga uyu.

Nusinersen jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira mamwe marabhara usati watanga kurapwa, usati wagamuchira dhosi rega rega, uye sezvazvinodiwa panguva yekurapa kutarisa mhinduro yemuviri wako kujekiseni re nusinersen.

Kumbira wemishonga wako chero mibvunzo yauinayo nezve nusinersen jekiseni.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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