Brigatinib

Zvemukati

• Usati watora brigatinib,
• Brigatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Brigatinib inoshandiswa kurapa imwe mhando yekenza isiri-diki yemapapu kenza (NSCLC) iyo yakapararira kune zvimwe zvikamu zvemuviri. Brigatinib ari mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kudzora kana kumisa kupararira kwekenza maseru.

Brigatinib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kamwe pazuva. Tora brigatinib panguva dzakatenderedza zuva rimwe nerimwe. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora brigatinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsvage kana kuapwanya.

Kana iwe ukarutsa mushure mekutora brigatinib, usatore imwe dosi. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako anogona kutanga iwe padosi yakaderera yebrigatinib uye wedzera yako dose kamwe mushure memazuva manomwe ekurapwa.

Chiremba wako angangoda kumbomira kurapwa kwenguva pfupi kana zvachose kana kudzikisa dhigiji yako yebrigatinib kana imwe mishonga yauri kutora, zvichienderana nemhedzisiro iwe yaunowana panguva yekurapwa kwako. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Usarega kutora brigatinib usina kutaura nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora brigatinib,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune brigatinib, chero mimwe mishonga, kana chero chinhu chinogadzirwa mumapiritsi ebrigatinib. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: antifungals senge itraconazole (Onmel, Sporanox, Tolsura), ketoconazole, buprenorphine uye naloxone (Suboxone), carbamazepine (Equetro, Tegretol, Teril, vamwe), clarithromycin, cyclosporine (Gengraf, Neoral ), diltiazem (Cardizem, Cartia, Diltzac, vamwe), efavirenz (Sustiva, muAtripla, Symfi), erythromycin (EES, Eryc, Erythrocin), indinavir (Crixivan), nefazodone, nelfinavir (Viracept), nevirapine (Virireptine) ; phenytoin (Dilantin, Phenytek), pioglitazone (Actos, muActoplus Met, Duetact, Oseni), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, muRifamate, muRifater), ritonavir (Norvir, muKaretraek, Technivie, sirolimus (Rapamune), tacrolimus (Astagraf, Envarsus, Prograf), kana verapamil (Calan, Verelan, muTarka). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana nebrigatinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana iwe kana wakambove neBP yakakwira; kurova kwemoyo kunononoka; chirwere cheshuga kana zvimwe zvinetso zveshuga muropa; kana hosha yeitsvo kana yechiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kuronga kubereka mwana. Brigatinib inogona kukanganisa chiito chehomoni yekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, majekiseni, kana majekiseni), saka haufanire kushandisa izvi senzira yako chete yekudzivirira kubereka panguva yekurapwa kwako. Iwe unofanirwa kushandisa isiri-mahormone yekuberekwa senzira yekudzivirira (mudziyo unodzivirira urume kuti usapinda muchibereko sekondomu kana diaphragm). Kumbira chiremba wako kuti akubatsire kusarudza nzira yekudzivirira kuberekwa iyo ichakushandira iwe. Kana iwe uri munhukadzi, iwe unozofanirwa kushandisa isiri-mahormone kuberekwa panguva yekurapa kwako uye kwemwedzi mina mushure mekupedzisira kwako dose. Kana iwe uri murume, iwe neumwe wako mukadzi mukadzi munofanira kushandisa kuberekwa panguva yekurapa uye rambai muchishandisa kuberekwa kwemwedzi mitatu mushure mekupedzisira komero yenyu. Brigatinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa panguva yekurapa kwako nebrigatinib uye kweinosvika svondo rimwe mushure mekupedzisira kwako.
• iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume. Taura nachiremba wako nezve njodzi dzekutora brigatinib.

Dzivisa kudya mazambiringa mazambiringa uye kunwa jisi remuzambiringa paunenge uchitora brigatinib.

Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Kana ukasuwa kutora brigatinib kwemazuva gumi nemana kana kupfuura, taura nachiremba wako usati watanga kuitora zvakare. Iwe uchafanirwa kutangazve kuitora iyo pazasi muyero.

Brigatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kusvotwa
• manyoka
• kurutsa
• kuvimbiswa
• kuneta
• mapundu
• musoro
• chiveve, kurwadziwa, kurira, kana kupisa kunzwa mutsoka kana maoko
• musana kana kurwadziwa kwemajoini
• kurasikirwa nenzara
• kunetseka kurara kana kuramba wakarara

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kutadza kufema kana kunetseka kufema
• kurwadziwa pachipfuva
• chikosoro pamwe kana pasina chikosoro
• kupindwa nechando
• kurwadziwa nemusoro, dzungu, hurema, kana kunzwa kupera simba
• kusaona kana kuona zvakapetwa
• achiona kupenya kwechiedza
• mwenje uchikuvadza maziso ako
• kuona '' mafloats '' kana madiki madiki
• nyota yakanyanya, kugara uchiita weti, kunyanyisa nzara, kusaona zvakanaka, kana kushaya simba
• kurwadziwa kwepamusoro mudumbu kunogona kupararira kumusana kana kuwedzera kuipa nekudya; kuonda; kana kusvotwa
• inononoka kana isina kujairika kurova kwemoyo
• kurwadziwa kwemhasuru, kuputika, unyoro, kana kushaya simba

Brigatinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira bvunzo bvunzo usati watanga kurapwa kwako kuti uone kana kenza yako inogona kurapwa nebrigatinib. Chiremba wako zvakare acharaira mamwe marabhoritari bvunzo uye ongorora yako yeropa usati uye panguva yekurapa kwako kuti utarise muviri wako kupindura brigatinib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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