Lorlatinib

Zvemukati

• Usati watora lorlatinib,
• Lorlatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Lorlatinib inoshandiswa kurapa imwe mhando yeasina-madiki maseru kenza yemapapu (NSCLC) iyo yakapararira kune mamwe mativi emuviri uye yawedzera mushure mekurapwa nemamwe mishonga yemakemikari. Lorlatinib ari mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kumisa kana kunonoka kupararira kwekenza masero.

Lorlatinib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kamwe pazuva. Tora lorlatinib kwakatenderedza nguva yakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora lorlatinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Kana iwe ukarutsa mushure mekutora mushonga, usatore imwe dosi. Enderera yako yenguva dzose dosing purogiramu.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya. Usatore mapiritsi akatoputswa kana kutsemuka.

Chiremba wako anogona kudzikisira muyero wako kana kumbomira kurapwa kwenguva pfupi kana zvachose zvichienderana nekuti unosangana nemimwe migumisiro. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako ne lorlatinib.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora lorlatinib,

• udza chiremba wako uye wemishonga kana uri weergoria kune lorlatinib, chero mimwe mishonga, kana chero chinhu chinogadzirwa nemapiritsi e lorlatinib. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako kana uri kutora carbamazepine (Epitol, Equetro, Carbatrol, Tegretol, Teril), efavirenz (Sustiva, muAtripla), nevirapine (Viramune), phenobarbital, phenytoin (Dilantin, Phenytek), pioglitazone (Actos, in Actop, in Actop ), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, muRifamate, Rifater), kana wort St. Chiremba wako angangokuudza kuti usatora lorlatinib kana uri kutora imwe kana yakawanda yemishonga iyi.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero yeanotevera: alprazolam (Xanax); calcium chiteshi blockers senge amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), felodipine (Plendil), nifedipine (Adalat, Procardia), nisoldipine (Sular), uye verapamil (Calan, Covera); mimwe mishonga yekurapa cholesterol yakawanda yakadai seatorvastatin (Lipitor) uye lovastatin (Mevacor); clarithromycin (Biaxin, muPrevpac); cyclosporine (Gengraf, Neoral, Sandimmune); diazepam (Valium); erythromycin (E.E.S, Erytab, Eryped); mimwe mishonga yekurapa HIV inosanganisira atazanavir (Reyataz, muEvotaz), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, in Kaletra, in Technivie), kana saquinavir (Invirase); itraconazole (Onmel, Sporanox); ketoconazole; midazolam; nefazodone; mishonga yekudzivirira pamuromo (mapiritsi ekudzivirira kubereka); quinidine (muNuedexta); sildenafil (Revatio, Viagra); sirolimus (Rapamune); tacrolimus (Prograf); tadalafil (Adcirca, Cialis); trazodone; triazolam (Halcion); kana vardenafil (Levitra, Staxyn). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana ne lorlatinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kana iwe wakambove nekurova kwemoyo zvisina kujairika, kushushikana, kufenda, huwandu hwecholesterol uye zvimwe zvinhu zvine mafuta muropa, kana chirwere chemapapu.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kuronga kubereka mwana. Lorlatinib inogona kukanganisa chiito chehomoni yekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, majekiseni, kana majekiseni), saka haufanire kushandisa izvi senzira yako chete yekudzivirira kubereka panguva yekurapa kwako. Iwe unofanirwa kushandisa isiri-mahormone yekuberekwa senzira yekudzivirira (mudziyo unodzivirira urume kuti usapinda muchibereko sekondomu kana diaphragm). Kumbira chiremba wako kuti akubatsire kusarudza nzira yekudzivirira kuberekwa iyo ichakushandira iwe. Kana iwe uri munhukadzi, iwe unozofanirwa kutora nhumbu yekubata usati watanga kurapwa uye unofanirwa kushandisa isiri-mahormone yekuzvarwa kudzivirira kubata nhumbu panguva yekurapwa kwako uye kwemwedzi mitanhatu mushure meyako yekupedzisira dosi. Kana iwe uri murume, iwe nemumwe wako mukadzi mukadzi munofanira kushandisa kuberekwa panguva yekurapwa uye kwemwedzi mitatu mushure mekupedzisira dosi. Taura nachiremba wako nezve nzira dzekudzivirira kuberekwa dzaunogona kushandisa panguva yekurapa kwako. Kana iwe kana mumwe wako ukava nepamuviri uchitora lorlatinib, danaidza chiremba wako nekukasira. Lorlatinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa-mwana paunenge uchitora lorlatinib uye kwemazuva manomwe mushure meyero yako yekupedzisira.
• iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka mune varume. Taura nachiremba wako nezve njodzi dzekutora lorlatinib.

Taura nachiremba wako nezve kudya mazambiringa uye kunwa jisi remuzambiringa paunenge uchitora mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana iri mukati maawa mana echirwere chinotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Lorlatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kurema kuwedzera
• mhasuru, kubatana, kana kurwadziwa musana
• manyoka
• kuvimbiswa
• kusvotwa
• kurutsa
• kuneta
• musoro
• maonero anochinja
• mapundu kana kuvava

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kuzvimba mumaoko ako, makumbo, maoko netsoka
• kunetseka kufema
• kufema kwekufema, kukosora, kana fivha
• chiveve uye kurira kwekunzwa mumajoini ako kana maoko nemakumbo
• kunetseka kufunga kana kuvhiringidzika
• pfari
• kuona zvinhu kana kunzwa manzwi zvisipo
• shanduko yemanzwiro, kunzwa kusuruvara kana kunetseka
• matambudziko nekutaura
• kunetseka kurara kana kuramba wakarara
• kujairika kurota kana kurota zvinotyisa
• dzungu, kunzwa kupera simba, kana kurova kwemoyo zvisina kujairika

Lorlatinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira kumwe kuongorora kwebazi uye electrocardiogram (ECG; bvunzo inoyera chiitiko chemagetsi mumoyo) usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune lorlatinib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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