Larotrectinib

Zvemukati

• Usati watora larotrectinib,
• Larotrectinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana icho chiri mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Larotrectinib inoshandiswa kurapa imwe mhando yemamota akasimba muvakuru uye vana 1 yemwedzi zera nekure akapararira kune dzimwe nhengo dzemuviri kana asingakwanise kurapwa zvinobudirira nekuvhiya. Mushonga uyu unoshandiswa chete kana pasina mamwe marapirwo aripo uye mapundu awedzera kuwanda mushure mekugamuchira kumwe kurapwa. Larotrectinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inotaurira maseru ekenza kuti awande. Izvi zvinogona kubatsira kudzora kukura kwemamota.

Larotrectinib inouya se capsule uye semhinduro (mvura) kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kaviri pazuva. Tora larotrectinib panguva dzakatenderedza nguva dzakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora larotrectinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza macapsule akazara nemvura; usatsvage kana kuapwanya.

Shandisa sirinji yemuromo (chiyero chekuyera) kunyatso kuyera uye tora yako dhizaini yelototrectinib mhinduro. Kumbira wemishonga wako nesirinji yemuromo kana imwe isina kubatanidzwa nemushonga wako. Usashandise teaspoon yemumba kuyera mhinduro. Tsiva sirinji yega yega mushure mekuishandisa kwemazuva manomwe kana ikakuvara. Tevedza rairo dzemugadziri nezve mashandisiro uye nekuchenesa sirinji yemuromo. Kumbira chiremba wako kana wemishonga kana iwe uine kana paine mibvunzo.

Kana iwe urikupa mhinduro kumwana, isa muromo wejekiseni remuromo mumuromo wemwana uchipesana nemukati medama. Chengeta mwana ari panzvimbo yakatwasuka kwemaminetsi mashoma achangopa dosi yelototrectinib. Kana mwana akasvipa imwe dose kana iwe usina chokwadi kuti rose dosi rakapihwa, usapa imwe dosi.

Kana iwe ukarutsa pakarepo mushure mekutora larotrectinib, usadzokorora muyero. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako angangoda kumbomira kurapwa kwenguva pfupi kana zvachose kana kudzikisa dhizaini yako yelototrectinib panguva yekurapa kwako. Izvi zvinoenderana nekuti mushonga unoshanda sei kwauri uye nemhedzisiro iwe yaunosangana nayo. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako nere larotrectinib.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora larotrectinib,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune larotrectinib, chero mimwe mishonga, kana chero chinhu chinogadzirwa nemarotrectinib capsules kana mhinduro. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: mamwe maantifungal akadai itraconazole (Onmel, Sporanox) uye ketoconazole; avanafil (Stendra); buspirone; clarithromycin (Biaxin, muPrevPac); mimwe mishonga yehutachiona hwehutachiona hweHIV (HIV) kana kuwana immunodeficiency syndrome (AIDS) senge efavirenz (Sustiva, muAtripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, muCaletra), uye saquinavir (Invirase); mimwe mishonga inodzvinyirira immune system yakadai seeverolimus (Afinitor, Zortress), sirolimus (Rapamune), uye tacrolimus (Astagraf, Envarsus XR, Prograf); lovastatin; midazolam; nefazodone; pioglitazone (Actos); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, muRifamate, muRifater); mimwe mishonga yekubatwa kwakadai se carbamazepine (Carbatrol, Epitol, Tegretol, vamwe), phenobarbital, uye phenytoin (Dilantin, Phenytek); sildenafil (Revatio, Viagra), simvastatin (Flolipid, Zocor); uye vardenafil (Levitra, Staxyn). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana nere larotrectinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isingaonekwe pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort. Usatora St. John's wort uchitora larotrectinib.
• udza chiremba wako kana iwe kana wakambove nemamiriro ezvinhu anokanganisa system yemitsipa kana chirwere chechiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kana iwe uronga nezve kubereka mwana. Kana iwe uri munhukadzi, iwe unozofanirwa kutora kutora nhumbu usati watanga kurapwa uye kushandisa kuberekwa kudzivirira kudzivirira kubata pamuviri panguva yekurapwa kwako uye kwevhiki rimwe mushure meyako yekupedzisira dosi. Kana iwe uri murume, iwe neako mukadzi mukadzi iwe unofanirwa kushandisa kuberekwa panguva yekurapwa kwako uye kwevhiki rimwe mushure meyako yekupedzisira dosi. Taura nachiremba wako nezve nzira dzekudzivirira kuberekwa dzaunogona kushandisa. Larotrectinib inogona kudzora kubereka muvakadzi. Nekudaro, iwe haufanire kufunga kuti haugone kuve nepamuviri. Kana iwe kana mumwe wako ukava nepamuviri, danaidza chiremba wako nekukurumidza. Larotrectinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa panguva yekurapa kwako uye kwevhiki rimwe mushure mekupedzisira kwako.
• iwe unofanirwa kuziva kuti larotrectinib inogona kukonzera kukotsira, dzungu, kana kuvhiringidzika. Usatyaire mota kana kushandisa michina kusvikira iwe waziva kuti uyu mushonga unokubata sei.

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Nekudaro, kana iri isingasviki maawa matanhatu pamberi peyadhi yako inotevera, ruka iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Larotrectinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kukosora
• kuvimbiswa
• manyoka
• kusvotwa
• kurutsa
• kurwadziwa nemudumbu
• musoro
• kuzara mumhino
• kurema kuwedzera
• mhasuru, kubatana, kana kurwadziwa musana
• kushaya simba kwemhasuru
• kuwedzera nyota; shandura muhuwandu kana ruvara rweweti; ganda rakaoma; kana kufenda

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana icho chiri mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kutaura kunonoka kana kuoma; kudonha netsaona; kana kurira, chiveve, kana kutsva kwekunzwa mumaoko ako netsoka
• kupindwa nechando
• kuzvimba mumaoko, tsoka, makumbo, kana makumbo ezasi
• mweya wekufema
• kuneta zvisina kujairika kana kushaya simba; kana ganda rakachenuruka
• kurasikirwa nenzara; kusvotwa; kurutsa; yero yeganda kana maziso; kana kurwadziwa muchikamu chepamusoro chekurudyi chedumbu

Larotrectinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Chengetera iwo makapuleti pane tembiricha yekamuri uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Chengeta mhinduro yemumuromo mufiriji uye yakavharwa zvine mutsindo; usaoma nechando. Rasa chero mushonga usingashandiswe wemuromo mazuva makumi mapfumbamwe mushure mekuvhura bhodhoro kekutanga.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo asati uye panguva yekurapa kuti aongorore mhinduro yemuviri wako kune larotrectinib. Kune mamwe mamiriro ezvinhu, chiremba wako acharaira bvunzo bvunzo usati watanga kurapwa kwako kuti uone kana kenza yako inogona kurapwa nere larotrectinib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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