Esketamine Nasal Spray

Zvemukati

• Usati washandisa esketamine nasal spray,
• Esketamine nasal spray inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

Kushandisa esketamine nasal spray kunogona kukonzera kugadzikana, kufenda, dzungu, kushushikana, kutenderera kwekunzwa, kana kunzwa kusabatana kubva mumuviri wako, pfungwa, manzwiro, nzvimbo uye nguva. Iwe unoshandisa esketamine nasal spray iwe pachako munzvimbo yekurapa, asi chiremba wako anozokutarisa pamberi, panguva, uye kweanenge maawa maviri mushure mekurapwa kwako. Iwe unozofanirwa kuronga kune muchengeti kana nhengo yemhuri kuti ikufambise kuenda kumba mushure mekushandisa esketamine. Mushure mekushandisa esketamine nasal spray, usatyaire mota, shandisa michina, kana kuita chero chinhu kwaunoda kuti uve wakangwarira zvachose kusvika zuva rinotevera mushure mekurara kwekuzorora kwehusiku. Udza chiremba wako ipapo ipapo kana iwe wakaneta zvakanyanya, kufenda, kurwadziwa pachipfuva, kufema kwekufema, kamwe kamwe musoro wakakomba, kuona kushanduka, kusazununguka kusingadzoreki kwechimwe chikamu chemuviri, kana kubatwa.

Esketamine inogona kunge iri tsika-inogadzira. Udza chiremba wako kana iwe kana chero munhu mumhuri yako achinwa kana akambonwa doro rakawanda, akashandisa kana akamboshandisa zvinodhaka zvemumugwagwa, kana kushandisa zvakanyanyisa mishonga yekunwa.

Chiverengero chidiki chevana, vachiri kuyaruka, uye vechidiki vakuru (vanosvika makore makumi maviri nemana ekuberekwa) vakatora mishonga yekudzvinyirira ('mamodho anosimudza') panguva yekiriniki zvidzidzo vakave kuzviuraya (kufunga nezvekuzvikuvadza kana kuzviuraya kana kuronga kana kuyedza kuzviita). Vana, vachiri kuyaruka, uye vechidiki vakuru vanotora mishonga yekudzvinyirira kurapa kushushikana kana zvimwe zvirwere zvepfungwa vangangoita mukana wekuzviuraya pane vana, vechidiki, uye vechidiki vasingatore mishonga yekudzvinyirira kurapa aya mamiriro. Nekudaro, nyanzvi hadzina chokwadi nezve hukuru hwenjodzi iyi uye kuti yakawanda sei iyo inofanirwa kutariswa mukusarudza kuti mwana kana wechidiki anofanira kutora chinodzvinyirira. Vana vanofanira kwete shandisa esketamine.

Iwe unofanirwa kuziva kuti hutano hwako hwepfungwa hunogona kuchinja nenzira dzisingatarisirwi paunoshandisa esketamine kana zvimwe zvinodzvinyirira kunyangwe uri munhu mukuru pamusoro pemakore makumi maviri nemana. Unogona kuzviuraya, kunyanya pakutanga kwekurapa kwako uye chero nguva iyo yako dosi yashandurwa. Iwe, mhuri yako, kana muchengeti wako unofanira kufonera chiremba wako ipapo ipapo kana iwe ukawana chero yeapi anotevera zviratidzo: kutsva kana kuwedzera kuora mwoyo; kufunga nezvekukuvadza kana kuzviuraya iwe, kana kuronga kana kuyedza kuzviita; kunetseka zvakanyanya; kusagadzikana; kutya kwekutya; kunetseka kurara kana kuramba wakarara; hutsinye hunhu; kutsamwa; kuita pasina kufunga; kusagadzikana kwakanyanya; uye kupenga kusingafadzi. Iva nechokwadi chekuti mhuri yako kana muchengeti anoziva kuti ndezvipi zviratidzo zvingave zvakakomba saka vanogona kufonera chiremba kana iwe usingakwanise kutsvaga kurapwa iwe wega.

Nekuda kwenjodzi nemushonga uyu, esketamine inowanikwa chete kuburikidza neakasarudzika chirongwa chekugovera. Chirongwa chinonzi Spravato Risk Evaluation uye Mitigation Strategies (REMS) chirongwa. Iwe, chiremba wako, uye chemishonga yako unofanirwa kunyoreswa muchirongwa cheSpravato REMS usati wagamuchira mushonga uyu. Iwe unoshandisa esketamine nasal spray munzvimbo yekurapa pasi pekucherechedzwa kwachiremba kana mumwe nyanzvi yehutano.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozotarisa yako yeropa usati uye kana maawa maviri mushure mekushandisa esketamine nguva imwe neimwe.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa ne esketamine uye nguva yega yega paunozadza tsamba yako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti kana webhusaiti yemugadziri kuti uwane iwo mushonga weMedication.

Esketamine nasal spray inoshandiswa pamwe chete nechimwe chinodzvinyirira, chinotorwa nemuromo, kugadzirisa kurapa-kusagadzikana kushushikana (TRD; kushushikana kusinga nyatso kurapwa) muvanhu vakuru. Inoshandiswawo pamwe chete neanodzvinyirira, inotorwa nemuromo, kurapa kushushikana kwezviratidzo kune vanhu vakuru vane hosha yekuora mwoyo (MDD) uye pfungwa dzekuzviuraya kana zviito. Esketamine iri mukirasi yemishonga inonzi NMDA vanogamuchira vanopokana. Inoshanda nekushandura chiitiko cheimwe yakasarudzika zvinhu muuropi.

Esketamine inouya semhinduro (mvura) kupuruzira mumhino. Kune manejimendi ekurapa-kusagadzikana kushushikana, kazhinji kunosaswa mumhuno kaviri pavhiki mukati memavhiki 1-4, kamwechete pasvondo mukati memavhiki mashanu kusvika ku8, uyezve kamwe pasvondo kana kamwe chete pavhiki mbiri pavhiki 9 uye mberi. Nekurapa kwekushushikana kwezviratidzo kune vanhu vakuru vane hombe kushushikana kwepfungwa uye pfungwa dzekuzviuraya kana zviito, zvinowanzo saswa mumhuno kaviri pasvondo kusvika kumavhiki mana. Esketamine inofanirwa kushandiswa mune yekurapa nzvimbo.

Usadya kwemaawa maviri kana kunwa zvinwiwa kwemaminitsi makumi matatu usati washandisa esketamine nasal spray.

Chinhu chega chega chemumhino chinopa mapiritsi maviri (imwe pfapfaidzo yemhino imwe neimwe). Mavara maviri akasvibira pachigadzirwa anokuudza kuti pfapfaidzo yemhino izere, rimwe dhi girini rinokuudza kuti imwe pfapfaidzo yakashandiswa, uye hapana madhiraivhi matema anoratidza kuti mushonga wakazara we2 mapiritsi wakashandiswa.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati washandisa esketamine nasal spray,

• udza chiremba wako uye wemishonga kana uri weergoria kune esketamine, ketamine, chero mimwe mishonga, kana chero chinhu chinowanikwa mu esketamine nasal spray. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: amphetamines, mishonga yekushushikana, armodafinil (Nuvigil), MAO inhibitors senge phenelzine (Nardil), procarbazine (Matulane), tranylcypromine (Parnate), uye selegiline (Eldepryl, Emsam, Zelapar); mimwe mishonga yechirwere chepfungwa, methylphenidate (Aptension, Jornay, Metadate, vamwe), modafanil, opioid (narcotic) mishonga yekurwadziwa, mishonga yekugumburwa, sedatives, kurara mapiritsi, uye tranquilizers. Udza chiremba wako kana iwe uchangobva kutora chero emimwe mishonga iyi.
• kana iwe uri kushandisa nasal corticosteroid yakadai ciclesonide (Alvesco, Omnaris, Zetonna) uye mometasone (Asmanex) kana nasal decongestant senge oxymetazoline (Afrin) uye phenylephrine (Neosynephrine), shandisa iri rinenge 1 awa usati washandisa esketamine nasal spray.
• udza chiremba wako kana iwe uine chirwere chemutsipa weropa muuropi, chipfuva, mudumbu nzvimbo, maoko kana makumbo; vane arteriovenous malformation (kuwirirana zvisina kujairika pakati petsinga dzako uye arteri); kana kuve nenhoroondo yekubuda ropa muuropi hwako. Chiremba wako angangokuudza kuti usashandise esketamine nasal spray.
• udza chiremba wako kana iwe wakamborohwa nesitiroko, chirwere chemwoyo, kukuvara kwehuropi, kana chero mamiriro ezvinhu anokonzera kuwedzera kwehuropi Udza chiremba wako kana iwe ukaona, unonzwa, kana kunzwa zvinhu zvisipo; kana kutenda muzvinhu zvisiri zvechokwadi. Zvakare, udza chiremba wako kana iwe kana wakambove uine chirwere chevhavhosi yemoyo, kutadza kwemoyo, hypertension (yakakwira BP), kurovera kunononoka kana kusajairika, kufema kwekufema, kurwadziwa pachipfuva, kana chiropa kana chirwere chemwoyo.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Kana iwe ukava nepamuviri uchishandisa esketamine nasal spray, danaidza chiremba wako nekukasira. Esketamine nasal spray inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa uchishandisa esketamine nasal spray.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikushandisa esketamine nasal spray.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Kana iwe ukarasikirwa nechirongwa chekurapa bata chiremba wako ipapo ipapo kuronga musangano. Kana iwe ukarasikirwa nemushonga uye kushushikana kwako kuri kuwedzera, chiremba wako angafanirwa kushandura dhizaini yako kana chirongwa chekurapa.

Esketamine nasal spray inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kazhinji, kukurumidza, kupisa, kana kurwadza weti
• kuvimbiswa
• manyoka
• muromo wakaoma
• kusvotwa
• kurutsa
• kunetseka kufunga kana kunzwa kudhakwa
• musoro
• isina kujairika kana esimbi kuravira mumuromo
• mhino kusagadzikana
• kutsamwa kwehuro
• kuwedzera kudikitira

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo zvakanyorwa muYAKAKOSHA YENYENZO, fonera chiremba wako nekukurumidza kana kuti uwane kurapwa kwekukurumidzira.

Esketamine nasal spray inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchishandisa mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Spravato^®