Upadacitinib

Zvemukati

• Usati watora upadacitinib,
• Upadacitinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Kutora upadacitinib kunogona kudzikisira kugona kwako kurwisa hutachiona uye kuwedzera njodzi yekuti uchawana hutachiona hwakakomba, kusanganisira zvakanyanya fungal, bhakitiriya, kana hutachiona hutachiona hunopararira nemuviri. Zvirwere izvi zvingangoda kurapwa muchipatara uye zvinogona kukonzera kufa. Udza chiremba wako kana iwe uchiwanzo kuwana chero hutachiona hutachiona kana kana iwe uchifunga kuti ungave uine chero hutachiona hutachiona izvozvi. Izvi zvinosanganisira hutachiona hushoma (sekucheka kana maronda akavhurika), hutachiona hunouya nekuenda (senge maronda anotonhora), uye hutachiona husingaperi husingaendi. Uyezve udza chiremba wako kana iwe kana wakambove nechirwere cheshuga, hutachiona hwehutachiona hwehutachiona (HIV), wakawana immunodeficiency syndrome (AIDS), chirwere chemapapu, kana chero imwe mamiriro ezvinhu anokanganisa immune system yako. Iwe unofanirwa zvakare kuudza chiremba wako kana iwe uchigara kana kuti wakambogara munzvimbo dzakadai seOhio kana Mississippi rwizi rwizi uko kwakanyanya hutachiona hutachiona hwakawanda. Kumbira chiremba wako kana iwe usina chokwadi kana hutachiona uhwu hwakajairika munharaunda yako. Udza chiremba wako kana uri kutora mishonga inoderedza mashandiro e immune system seaya anotevera: azathioprine (Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), hydroxychloroquine (Plaquenil), leflunomide (Arava), methotrexate (Otrexup, Rasuvo , Trexall); steroids inosanganisira dexamethasone, methylprednisolone (Medrol), prednisolone (Prelone), uye prednisone (Rayos); sulfasalazine; kana tacrolimus (Astagraf, Envarsus XR, Prograf).

Chiremba wako anokucherechedza iwe nezviratidzo zvehutachiona panguva uye mushure mekurapa kwako. Kana iwe uine chero cheanotevera zviratidzo usati watanga kurapwa kwako kana kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchirapwa, dana chiremba wako nekukasira: fever; vangadikitira; chills; tsandanyama aches; kukosora; mweya wekufema; kuonda; inodziya, tsvuku, kana inorwadza ganda; maronda paganda; kazhinji, kunorwadza, kana kutsva kwekunzwa panguva yekuita weti; manyoka, kana kuneta zvakanyanya.

Unogona kunge uine hutachiona (TB; chirwere chakakomba chemapapu) asi usina zviratidzo zvechirwere. Muchiitiko ichi, kutora upadacitinib kunogona kuita kuti hutachiona hwako huwedzere uye huite kuti iwe uve nezviratidzo. Chiremba wako achaita bvunzo yeganda kuti aone kana uine hutachiona hweTB husinga shande usati watanga kurapwa kwako ne upadacitinib. Kana zvichidikanwa, chiremba wako achakupa mishonga yekurapa hutachiona usati watanga kushandisa upadacitinib. Udza chiremba wako kana wakambove neTB kana kuti wakambove neTB, kana wakambogara kana kushanyira nyika ine TB yakajairika, kana kuti kana wakambove pedyo nemunhu ane TB. Kana iwe uine chero cheanotevera zviratidzo zveTB, kana kana iwe ukaita chero eapi eaya maratidziro panguva yekurapwa kwako, fonera chiremba wako nekukasika: kukosora, kukosora mamota ane ropa, kuonda, kurasikirwa kwemhasuru toni, kana fivha.

Kutora upadacitinib kunogona kuwedzera njodzi yekuti uchaita lymphoma (kenza inotanga mumasero anorwisa hutachiona) kana mamwe marudzi ekenza senge kenza yeganda. Udza chiremba wako kana iwe wakambove kana chero rudzi rwekenza.

Upadacitinib inogona kuwedzera njodzi yekukomba uye nekutyisidzira hupenyu ropa kuwanda mumapapu kana makumbo. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinzwa mweya wekufema; kukosora; kurwadziwa, kudziya, kutsvuka, kuzvimba, kana unyoro hwemakumbo; kana kutonhora kunzwa mukati memaoko, maoko, kana makumbo; kana kurwadziwa kwemhasuru.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira kumwe kuongorora kwebhu kare, panguva, uye mushure mekurapwa kwako kuti utarise mhinduro yemuviri wako kuupadacitinib.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Mishonga Inotungamira) paunotanga kurapwa neupadacitinib uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi (s) dzekutora upadacitinib.

Upadacitinib inoshandiswa yoga kana nemimwe mishonga kurapa rheumatoid arthritis (mamiriro ayo muviri unorwisa majoini ayo achikonzera kurwadziwa, kuzvimba, uye kurasikirwa nebasa) muvanhu vasina kupindura zvakanaka kune methotrexate (Otrexup, Rasuvo, Trexall). Upadacitinib iri mukirasi yemishonga inonzi Janus kinase (JAK) inhibitors. Inoshanda nekuderedza mashandiro e immune immune.

Upadacitinib inouya seyakawedzerwa-kuburitsa (refu-inoshanda) piritsi. Inowanzo kutorwa pamwe kana pasina chikafu kamwe pazuva. Tora upadacitinib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora upadacitinib chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mahwendefa akasunungurwa-akazara; usatsemure, kutsenga, kana kuvapwanya.

Chiremba wako angangoda kumbomira kurapwa kwenguva pfupi kana zvechigarire kana iwe uchinge wawana mamwe akanyanya mhedzisiro. Ive neshuwa yekuudza chiremba wako kuti unonzwa sei panguva yekurapwa kwako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora upadacitinib,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune upadacitinib, chero mimwe mishonga, kana chero chipi chezvinhu zvinosanganiswa mumapiritsi eupadacitinib akawedzerwa-kuburitswa. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: mamwe antifungal mishonga senge itraconazole (Onmel, Sporanox) uye ketoconazole; asipurini uye mamwe nonsteroidal anti-anogumbura mishonga (NSAIDs) senge ibuprofen (Advil, Motrin) uye naproxen (Naprosyn, Aleve); barbiturates senge phenobarbital kana phenytoin (Dilantin, Phenytek); carbamazepine (Carbatrol, Tegretol, Equetro, nevamwe); clarithromycin (Biaxin, muPrevpac); enzalutamide (Xtandi); mimwe mishonga yeHIV inosanganisira efavirenz (Sustiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, muKaletra), uye saquinavir (Invirase); nefazodone; rifabutin (Mycobutin); kana rifampin (Rifadin, Rimactane, muRifamate, muRifater). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kusangana neupadacitinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isingaonekwe pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's Wort.
• udza chiremba wako kana iwe uine maronda (maronda ari mukati memukati medu kana ura), diverticulitis (kuzvimba kwemukati mematumbo makuru), herpes zoster (shingles; rash inogona kuitika kune vanhu vane chickenpox munguva yakapfuura. ), kana kupererwa neropa (yakaderera pane yakajairwa nhamba yemasero matsvuku eropa), kana chirwere chechiropa, kusanganisira hepatitis B kana C.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe unozofanirwa kuve nemimba yekubata usati watanga kurapwa neupadacitinib. Iwe unofanirwa kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapa kwako uye kweanenge mavhiki mana mushure mekupedzisira kwako dose. Taura nachiremba wako nezve nzira dzekudzivirira kuberekwa dzaunogona kushandisa. Kana iwe ukava nepamuviri, danaidza chiremba wako pakarepo. Upadacitinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa panguva yekurapa kwako neupadacitinib uye kwemazuva matanhatu mushure mekupedzisira kwedosi.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora upadacitinib.
• udza chiremba wako kana iwe uchangobva kugamuchira kana kuti wakarongerwa kupihwa chero majekiseni. Kana iwe uchida chero majekiseni, iwe ungatofanira kugamuchira majekiseni uye womirira imwe nguva usati watanga kurapwa kwako neupadacitinib. Hauna majekiseni panguva yekurapa kwako pasina kutaura nachiremba wako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Upadacitinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• yakakora kana inomhanya mhino
• kusvotwa

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• yero yeganda kana maziso, kurasikirwa nenzara, rima weti, kana ivhu-rakatsvuka ura kufamba
• kupfupika kwemweya wekufema, kuneta, kana ganda rakachenuruka

Upadacitinib inogona kukonzera kuwedzera kweropa rako remafuta akawandisa. Chiremba wako acharaira bvunzo kuti atarise cholesterol yako panguva yekurapa kwako neupadacitinib. Taura nachiremba wako nezve njodzi dzekutora mushonga uyu.

Upadacitinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze kungave mufiriji kana tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete mubhavhu).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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