Munyori: Clyde Lopez
Zuva Rekusika: 19 Chikunguru 2021
Gadziridza Zuva: 19 Mbudzi 2024
Anonim
Voxelotor An Investigational Drug for Sickle Cell Disease
Vhidhiyo: Voxelotor An Investigational Drug for Sickle Cell Disease

Zvemukati

Voxelotor inoshandiswa kurapa sickle cell chirwere (chirwere chakagarwa nhaka muropa) muvakuru nevana vane makore gumi nemaviri zvichikwira. Voxelotor iri mukirasi yemishonga inonzi hemoglobin S (HbS) polymerization inhibitors. Inoshanda nekubatsira hemoglobin (puroteni mumasero matsvuku eropa) kubatirira pane yakawanda okisijeni uye kumisa masero matsvuku eropa kubva pakuva misshapen.

Voxelotor inouya sehwendefa kutora nemuromo. Inowanzo kutorwa kamwe chete zuva nezuva kana kana pasina chikafu. Tora voxelotor panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora voxelotor chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.


Usati watora voxelotor,

  • udza chiremba wako uye wemishonga kana uri weergoria kune voxelotor, chero mimwe mishonga, kana chero chinhu chinowanikwa mumapiritsi evoxelotor. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: mamwe antifungals senge fluconazole (Diflucan), itraconazole (Onmel, Sporanox), kana ketoconazole; carbamazepine (Tegretol); clarithromycin (Biaxin, muPrevpac); diltiazem (Cardizem, Cartia, Diltzac, Taztia); erythromycin (E-Mycin, Erythrocin); mishonga yekurapa HIV inosanganisira didanosine (Videx), efavirenz (Sustiva, muAtripla), nelfinavir (Viracept), ritonavir (Norvir, muCaletra), kana saquinavir (Fortovase, Invirase); nefazodone; phenobarbital; phenytoin (Dilantin); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, muRifamate, muRifater); kana oral steroids senge dexamethasone, methylprednisolone (Medrol), uye prednisone (Rayos). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
  • udza chiremba wako kana iwe wakambove kana wakambove nechirwere chechiropa.
  • udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Kana iwe ukava nepamuviri uchitora voxelotor, fonera chiremba wako.
  • udza chiremba wako kana iwe uchiyamwisa. Usamwisa mwana paunenge uchitora voxelotor uye kwemavhiki maviri mushure mekupedzisira kwako.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora voxelotor.

Taura nachiremba wako nezve kudya mazambiringa uye kunwa jisi remuzambiringa paunenge uchitora mushonga uyu.


Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu zuva rinotevera.

Voxelotor inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • musoro
  • manyoka
  • kurwadziwa nemudumbu
  • kusvotwa
  • kupindwa nechando

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, rega kutora voxelotor uye kufonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • mapundu, mikoko, kufema kwekufema, kana kuzvimba kumeso

Voxelotor inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).


Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako.

Usati waita chero bvunzo yerabhoritari, udza chiremba wako nevashandi veirabhoritari kuti uri kutora voxelotor.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Oxbryta®
Yekupedzisira Yakagadziridzwa - 02/15/2020

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