Munyori: Virginia Floyd
Zuva Rekusika: 7 Nyamavhuvhu 2021
Gadziridza Zuva: 1 Mbudzi 2024
Anonim
Valproic acid || Mechanism, side effects and indications
Vhidhiyo: Valproic acid || Mechanism, side effects and indications

Zvemukati

Divalproex sodium, valproate sodium, uye valproic acid, ese mishonga yakafanana iyo inoshandiswa nemuviri sevalproic acid. Naizvozvo, izwi valproic asidhi ichashandiswa kumiririra iyi yese mishonga iyi muhurukuro iyi.

Valproic acid inogona kukonzera zvakakomba kana kutyisidzira hupenyu kuchiropa izvo zvinonyanya kuitika mukati memwedzi mitanhatu yekutanga yekurapa. Dambudziko rekukuvara kwechiropa rakakura muvana vari pasi pemakore maviri ekuberekwa uye vari kutora mishonga inopfuura imwechete kudzivirira kubata, vane zvimwe zvirwere zvakagarwa nhaka zvinogona kudzivirira muviri kubva mukuchinja chikafu kuita simba zvakajairika, kana chero mamiriro inokanganisa kugona kufunga, kudzidza, uye kunzwisisa. Udza chiremba wako kana iwe uine chimwe chinhu chakagarwa nhaka chinokanganisa huropi, mhasuru, tsinga, uye chiropa (Alpers Huttenlocher Syndrome), urea kutenderera kusagadzikana (iyo nhaka nhaka mamiriro ayo anokanganisa kugona kugadzirisa metabolism), kana chirwere chechiropa. Chiremba wako angangokuudza kuti usatora valproic acid. Kana iwe ukacherekedza kuti kubatwa kwako kwakanyanya kana kuitika kakawanda kana kana ukasangana nechimwe chezviratidzo zvinotevera, fonera chiremba wako nekukasira: kuneta zvakanyanya, kushaya simba, kushaya simba, kurwadziwa kurudyi kwedumbu rako, kurasikirwa nenzara, kusvotwa, kurutsa ,, weti yakasviba, yero yeganda rako kana machena eziso rako, kana kuzvimba kwechiso.


Valproic acid inogona kukonzera kuremara kwakakomba kuberekwa (matambudziko epanyama aripo pakuzvarwa), kunyanya kukanganisa huropi uye musana uye zvinogona kukonzeresa huchenjeri nematambudziko nekufamba pamwe nekubatana, kudzidza, kutaurirana, manzwiro, uye hunhu muvacheche vakafumurwa kune valproic asidhi asati aberekwa. Udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Vakadzi vane nhumbu kana vanokwanisa kuve nepamuviri uye vasiri kushandisa zvinobudirira kudzora havafanirwe kutora valproic acid kudzivirira migraine kutemwa nemusoro. Vakadzi vane nhumbu vanofanirwa kungotora valproic acid kurapa pfari kana bipolar kusagadzikana (manic-depress disorder, chirwere chinokonzeresa zvikamu zvekushungurudzika, episodes of mania, uye mamwe mafungire asina kujairika) kana mimwe mishonga isina kubudirira kudzora zviratidzo zvavo kana kuti isingakwanise kuva kushandiswa. Taura nachiremba wako nezve njodzi dzekushandisa valproic acid panguva yekuzvitakura. Kana iwe uri mukadzi ane zera rekubereka, kusanganisira vasikana kubva pakutanga kwekuyaruka, taura nachiremba wako nezve kushandisa mamwe marapirwo anogona kuitika pane valproic acid. Kana sarudzo ikaitwa kushandisa valproic acid, unofanirwa kushandisa zvinoshanda pakuberekwa panguva yekurapa kwako. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri uchitora valproic acid, dana chiremba wako nekukurumidza. Valproic acid inogona kukuvadza fetus.


Valproic acid inogona kukonzera zvakakomba kana kutyisidzira hupenyu kumanyoka. Izvi zvinogona kuitika chero nguva panguva yekurapa kwako. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, danaidza chiremba wako nekukasira: kurwadziwa kunoramba kuripo kunotanga mudumbu asi kunogona kupararira kumusana kusvotwa, kurutsa, kana kurasikirwa nechido.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira mamwe malebhu bvunzo kuti atarise mhinduro yako kune valproic acid.

Taura nachiremba wako nezve njodzi dzekutora valproic acid kana yekupa valproic acid kumwana wako.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Gwaro RezveMishonga) paunotanga kurapwa nevalproic acid uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.


Valproic acid inoshandiswa yoga kana nemimwe mishonga kurapa mamwe marudzi ekubatwa. Valproic acid inoshandiswawo kurapa mania (episodes of frenzied, abnormally mood mood) muvanhu vane bipolar disorder (manic-depression disorder; chirwere chinokonzera zvikamu zvekushungurudzika, episodes of mania, uye mamwe mafungiro asina kujairika). Inoshandiswa zvakare kudzivirira migraine misoro asi kwete kusunungura misoro yakatotanga. Valproic acid iri mukirasi yemishonga inonzi anticonvulsants. Inoshanda nekuwedzera huwandu hwechimwe chinhu chechisikigo muuropi.

Valproic acid inouya secapsule, yakawedzera-kuburitsa (yakareba-inoshanda) piritsi, kunonoka-kuburitsa (inoburitsa mushonga mumatumbo kudzivirira kukuvara mudumbu) piritsi, inosasa capsule (kapuleti ine zvidiki zvidiki zvemushonga izvo inogona kusaswa pane chikafu), uye manyuchi (mvura) kutora nemuromo. Iyo sirasi, makapisi, anonoka-kuburitsa mapiritsi, uye kumwaya macapsule anowanzo kutorwa kaviri kana kupfuura nguva zuva nezuva. Mahwendefa akasunungurwa-anowanzotorwa kamwe chete pazuva. Tora valproic acid panenge panguva imwechete (ma) mazuva ese. Tora valproic acid nechikafu kubatsira kudzivirira mushonga kubva mukugumbura dumbu rako. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora valproic acid chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza macapsule enguva dzose, kunonoka-kuburitsa capsule, uye akawedzera-kusunungura mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.

Iwe unogona kumedza macapsule akasaswa akazara, kana iwe unogona kuvhura iwo makapisi uye nekusasa marozari avanenge aine mupasipuni yechikafu chinyoro, senge applesauce kana pudding. Medza musanganiswa wezvokudya nemishonga marozari uchangogadzirira. Ngwarira kuti usatsenga hura. Usachengete mishonga isinga shandiswe yechikafu nemishonga.

Usasanganisa sirasi mune chero chinwiwa chine kabhoni.

Divalproex sodium, valproate sodium, uye valproic acid zvigadzirwa zvinosanganiswa nemuviri nenzira dzakasiyana uye hazvigone kuchinjaniswa. Kana iwe uchida kuchinja kubva kune chimwe chigadzirwa uchienda pane chimwe, chiremba wako angangoda kugadzirisa yako dose. Nguva imwe neimwe yaunogamuchira mishonga yako, tarisa kuti uve nechokwadi chekuti wagamuchira chigadzirwa chawakatemerwa iwe. Bvunza wako wemishonga kana iwe usina chokwadi chekuti wakagamuchira chaiyo mishonga.

Chiremba wako anogona kukutanga iwe pane yakaderera dosi yevalproic acid uye zvishoma nezvishoma wedzera yako dose.

Valproic acid inogona kubatsira kudzora mamiriro ako asi haizorape. Ramba uchitora valproic acid kunyangwe iwe uchinzwa zvakanaka. Usarega kutora valproic acid usina kutaura nachiremba wako, kunyangwe iwe ukava nemhedzisiro senge shanduko isina kujairika mukuzvibata kana mafungiro kana ukaona kuti une nhumbu. Kana iwe ukangoerekana warega kutora valproic acid, unogona kusangana neakakomba, anogara kwenguva refu uye pamwe anogona kutyisidzira hupenyu. Chiremba wako angangoderedza dhizaini yako zvishoma nezvishoma.

Valproic acid zvakare dzimwe nguva inoshandiswa kurapa kuputika kwehasha muvana vane hanya nekushomeka kwehutano kusagadzikana (ADHD; kunetsekana kutarisa kana kuramba wakanyarara kana kunyarara pane vamwe vanhu vanezera rakaenzana). Taura nachiremba wako nezve njodzi dzinogona kuitika dzekushandisa mushonga uyu kune ako mamiriro.

Mushonga uyu dzimwe nguva unonyorerwa kumwe kushandiswa. Kumbira chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora valproic acid,

  • udza chiremba wako uye wemishonga kana iwe uri weergoria kune valproic acid, chero mimwe mishonga, kana chero chinhu chinosanganiswa murudzi rwevalproic acid iyo yawakatemerwa iwe. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: acyclovir (Zovirax), anticoagulants ('blood thinner') senge warfarin (Coumadin), amitriptyline, aspirin, carbamazepine (Tegretol), cholestyramine (Prevalite), clonazepam (Klonopin), diazepam (Valium ), doripenem (Doribax), ertapenem (Invanz), ethosuximide (Zarontin), felbamate (Felbatol), mamwe mahomoni ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, mhete, zvigamba, zvinomira, majekiseni, uye zvishandiso zvepamuviri), imipenem uye cilastatin (Primaxin), lamotrigine (Lamictal), mishonga yekushushikana kana chirwere chepfungwa, meropenem (Merrem), nortriptyline (Pamelor), phenobarbital, phenytoin (Dilantin), primidone (Mysoline), rifampin (Rifadin), rufinamide (Banzel), sedatives, kurara mapiritsi, tolbutamide , topiramate (Topamax), tranquilizers, uye zidovudine (Retrovir). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana iwe kana wakambove nezvikamu zvekuvhiringidzika uye kurasikirwa kwekugona kufunga nekunzwisisa, kunyanya panguva yepamuviri kana yekusununguka; coma (kurasikirwa kwekuziva kwenguva yakati); kuoma kurongedza mafambiro ako; hutachiona hwehutachiona hwehutachiona hweHIV (HIV); kana cytomegalovirus (CMV; hutachiona hunogona kukonzeresa zviratidzo muvanhu vane immune system isina kusimba).
  • udza chiremba wako kana iwe uchiyamwisa.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora valproic acid.
  • iwe unofanirwa kuziva kuti valproic acid inogona kukutsira iwe. Usatyaire mota kana kushandisa michina kusvikira iwe waziva kuti uyu mushonga unokubata sei.
  • rangarira kuti doro rinogona kuwedzera kuhope dzinokonzerwa nemushonga uyu.
  • iwe unofanirwa kuziva kuti valproic acid inogona kukotsira zvakanyanya izvo zvinogona kukukonzera kuti udye kana kunwa zvishoma pane zvawaimboita, kunyanya kana iwe uri mukuru. Udza chiremba wako kana iwe usingakwanise kudya kana kunwa sezvaunowanzoita.
  • iwe unofanirwa kuziva kuti hutano hwako hwepfungwa hunogona kuchinja nenzira dzisingatarisirwi uye unogona kuzviuraya (kufunga nezvekuzvikuvadza kana kuzviuraya kana kuronga kana kuyedza kuzviita) paunenge uchitora valproic acid yekurapa pfari, kurwara nepfungwa, kana mamwe mamiriro . Chiverengero chidiki chevakuru uye vana vane makore mashanu ekuberekwa uye kupfuura (vangangoita 1 muvanhu mazana mashanu) vakatora anticonvulsants senge valproic acid kurapa akasiyana mamiriro panguva yekiriniki yekudzidzira kuzviuraya panguva yekurapwa kwavo. Vamwe vevanhu ava vakaita pfungwa dzekuzviuraya pamwe nehunhu pakutanga kwevhiki rimwe chete vatanga kutora mushonga. Pane njodzi yekuti unogona kusangana neshanduko muhutano hwepfungwa kana ukatora mishonga inorwisa antivulsion yakadai sevalproic acid, asi pangave nenjodzi yekuti iwe uchaona shanduko muhutano hwako hwepfungwa kana mamiriro ako asina kurapwa. Iwe nachiremba wako muchasarudza kana njodzi dzekutora mushonga weanticonvulsant dzakakura kudarika njodzi dzekusatora mushonga. Iwe, mhuri yako, kana mutarisiri wako unofanirwa kufonera chiremba wako ipapo kana iwe ukawana chero cheanotevera zviratidzo: kuvhunduka kwekutya; kusagadzikana kana kusagadzikana; kutsva kana kuwedzera kutsamwa, kushushikana, kana kushushikana; kuita zvishuvo zvine ngozi; kunetseka kudonha kana kuramba wakarara; hasha, hasha, kana kuita zvechisimba; mania (kupenga, kusanzwisisika zvisingaite); kutaura kana kufunga nezvekuda kuzvikuvadza kana kupedza hupenyu hwako; kurega shamwari nemhuri; kubatikana nerufu nekufa; kupa zvinhu zvinokosha; kana chero imwe shanduko isina kujairika mumaitiro kana manzwiro. Iva nechokwadi chekuti mhuri yako kana muchengeti anoziva kuti ndezvipi zviratidzo zvingave zvakakomba saka vanogona kufonera chiremba kana iwe usingakwanise kutsvaga kurapwa iwe wega.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva yako inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Valproic acid inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kutsimwaira
  • dzungu
  • musoro
  • manyoka
  • kuvimbiswa
  • kuchinja mukudya
  • uremu hunochinja
  • kurwadziwa shure
  • kusagadzikana
  • mafungiro
  • kufunga zvisina kujairika
  • kuzunza kusingadzoreki nhengo yemuviri
  • matambudziko nekufamba kana kubatana
  • kusadzora kufamba kwemeso
  • kusaona kana kuona zvakapetwa
  • kurira munzeve
  • kurasikirwa nevhudzi

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO kana CHIKAMU CHENYAYA, daidza chiremba wako nekukasira:

  • kupwanya kusingawanzo kana kubuda ropa
  • madiki epepuru kana matsvuku paganda
  • kupindwa nechando
  • mapundu
  • kukuvadza
  • mikoko
  • kunetseka kufema kana kumedza
  • kuzvimba gland
  • kuzvimba kwechiso, maziso, miromo, rurimi, kana huro
  • kubvarura kana kubvarura ganda
  • kuvhiringidzika
  • kuneta
  • kurutsa
  • kudonha tembiricha yemuviri
  • kushaya simba kana kuzvimba mumajoini

Valproic acid inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pamhepo tembiricha, kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • hope
  • kurova kwemoyo zvisina kujairika
  • coma (kurasikirwa kwekuziva kwenguva yakati)

Kana iwe uri kutora anosasa macapsule, iwe unogona kuona iwo mishonga marozari mune chako chigaro. Izvi zvakajairika uye hazvireve kuti iwe hauna kuwana yakazara yakazara mushonga.

Kana iwe uine chirwere cheshuga uye chiremba wako akakuudza kuti uedze weti yako ketoni, udza chiremba kuti uri kutora valproic acid. Valproic acid inogona kukonzeresa mhedzisiro pakuongorora weti kune ketoni.

Usati waita chero bvunzo yerabhoritari, udza chiremba wako nevashandi veirabhoritari kuti uri kutora valproic acid.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Depakene®
  • Depakote®
  • Depakote® ER
  • Depakote® Fwanya
  • Divalproex sodium
  • Valproate sodium
Yekupedzisira Yakagadziridzwa - 04/15/2019

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