Munyori: Marcus Baldwin
Zuva Rekusika: 18 Chikumi 2021
Gadziridza Zuva: 19 Mbudzi 2024
Anonim
How does Niacin (B3) Work? (+ Pharmacology)
Vhidhiyo: How does Niacin (B3) Work? (+ Pharmacology)

Zvemukati

Niacin inoshandiswa nekuchinja kwekudya (kudzivirirwa kwecholesterol uye kudya kwemafuta) kudzikisa huwandu hwecholesterol (chinhu chakaita semafuta) nezvimwe zvinhu zvine mafuta muropa rako uye kuwedzera huwandu hwehuwandu hwehupamhi lipoprotein (HDL; '' cholesterol yakanaka ''). Niacin inogona kushandiswa mune akati wandei ezvinhu kusanganisira zvinotevera:

  • oga kana musanganiswa nemimwe mishonga, yakadai seHMG-CoA inhibitors (statins) kana bile acid-inosunga resini;
  • kudzikisa njodzi yekumwe kurwiswa kwemoyo muvarwere vane cholesterol yakakwira avo vakarwara nemoyo;
  • kudzivirira kuwedzera kwe atherosclerosis (kuwanda kwecholesterol nemafuta pamadziro emidziyo yeropa) kune varwere vane cholesterol yakakura uye coronary artery chirwere;
  • kudzikisa huwandu hwe triglycerides (mamwe mafuta zvinhu) muropa mune varwere vane yakakwirira kwazvo triglycerides vari panjodzi yechirwere chepancreatic (mamiriro anokanganisa rwatata, gland rinoburitsa hunyoro kuputsa chikafu uye mahormone kudzora shuga yeropa).

Niacin inoshandiswawo kudzivirira pamwe nekurapa pellagra (kushomeka niacin), chirwere chinokonzerwa nekudya kusakwana uye mamwe matambudziko ekurapa. Niacin vitamini B-yakaoma. Pamishonga yekurapa, niacin ndeye cholesterol-inoderedza mishonga.


Mhedzisiro yechiriniki yekudzidza mune vanhu vane chirwere chemoyo uye inodzorwa-zvakanaka cholesterol mwero iyo yakafananidza vanhu vakatora niacin uye simvastatin nevanhu vakatora simvastatin vega uye vakawana mhedzisiro yakafanana kumapoka maviri ari muyero wekurwadziwa kwemoyo kana kurohwa. Kutora niacin pamwe chete ne simvastatin kana lovastatin zvakare haina kuratidzwa kudzikisa njodzi yechirwere chemwoyo kana kufa ichienzaniswa nekushandisa niacin, simvastatin, kana lovastatin chete. Taura nachiremba wako kana iwe uine mibvunzo nezve njodzi uye mabhenefiti ekurapa yakawedzera huwandu hwecholesterol muropa rako neNiacin nemimwe mishonga.

Niacin inouya sehwendefa uye yakawedzerwa-kuburitsa (refu-inoshanda) piritsi yekutora nemuromo. Iyo piritsi yakajairwa kazhinji inotorwa kaviri kana katatu pazuva nekudya, uye iyo yakawedzeredzwa-kuburitsa piritsi inotorwa kamwe pazuva, panguva yekurara, mushure mekudya kwemafuta mashoma. Tevedza madhairekitori akanyorwa pachiraira chako kana pasuru zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora niacin chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Medza mahwendefa akasunungurwa-akazara; usatsemure, kutsenga, kana kuvapwanya.

Chiremba wako angangotanga iwe pane yakaderera dosi ye niacin uye zvishoma nezvishoma uwedzere muyero wako.

Ramba uchitora niacin kunyangwe iwe uchinzwa zvakanaka. Usarega kutora niacin usina kutaura nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu dzimwe nguva unonyorerwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora niacin,

  • udza chiremba wako uye wemishonga kana iwe uri weergoria kune niacin, chero mimwe mishonga, kana chero chimwe chezvinhu zvinosanganiswa mumapiritsi e niacin. Kumbira mushonga wako wemishonga kana kutarisa ruzivo rwemugadziri kune murwere kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: anticoagulants ('blood thinner') senge warfarin (Coumadin); aspirin; insulin kana mishonga yemumuromo yechirwere cheshuga; mishonga yehigh blood pressure; zvinovaka muviri zvekuwedzera kana zvimwe zvigadzirwa zvine niacin; kana imwe mishonga yekudzikisa cholesterol kana triglycerides. Kana iwe ukatora insulin kana mukanwa chirwere cheshuga, wako mwero ungangoda kuchinjwa nekuti niacin inogona kuwedzera huwandu hweshuga muropa rako uye weti.
  • kana iwe uri kutora bile acid-inosunga resin yakadai secolestipol (Colestid) kana cholestyramine (Questran), tora kanenge maawa mana kusvika matanhatu usati wasvika kana maawa mana kusvika matanhatu kusvika niacin.
  • udza chiremba wako kana iwe uchinwa yakawanda doro uye kana iwe uine kana wakambove uine chirwere cheshuga; gout; maronda; chisimbwa; jaundice (yero yeganda kana maziso); matambudziko ekubuda ropa; kana nduru, moyo, itsvo, kana chirwere chechiropa.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora niacin, rega kutora niacin uye udane chiremba wako.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti uri kutora niacin.
  • bvunza chiremba wako nezve kushandiswa kwakachengeteka kwezvinwiwa zvinodhaka paunenge uchitora niacin. Doro rinogona kuita kuti mhedzisiro kubva kuNiacin inyanye.
  • iwe unofanirwa kuziva kuti niacin inokonzeresa kutsvuka (kutsvuka, kudziya, kuchenesa, kurira) kwechiso, mutsipa, chifuva, kana musana. Iyi divi mhedzisiro inowanzoenda mushure mekutora mushonga kwevhiki dzinoverengeka. Dzivisa kunwa doro kana zvinwiwa zvinopisa kana kudya zvekudya zvinonhuwirira panguva yaunotora niacin. Kutora aspirin kana imwe nonsteroidal anti-inflammatory drug yakadai sebuprofen (Advil, Motrin) kana naproxen (Aleve, Naprosyn) maminetsi makumi matatu pamberi pe niacin inogona kudzikisa kubhururuka. Kana iwe ukatora yakawedzerwa-kuburitsa niacin panguva yekurara, kumhanyisa kwacho kunogona kuitika iwe paunenge wakarara. Kana iwe ukamuka uye uchinzwa kumeso, simuka zvishoma, kunyanya kana uchinzwa dzungu kana kupera simba.

Idya yakaderera-mafuta, yakaderera-cholesterol chikafu. Ive neshuwa yekutevera zvese zvekurovedza muviri uye zvekudya zvinokurudzirwa zvakaitwa nachiremba wako kana wezvekudya. Iwe unogona zvakare kushanyira iyo National Cholesterol Dzidzo Chirongwa (NCEP) webhusaiti kune rumwe ruzivo rwekudya pa http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.


Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Kana iwe ukarega kutora niacin chero nguva yakareba, daidza chiremba wako usati watanga kuitora zvakare.

Niacin inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • manyoka
  • kuwedzera kukosora

Kana iwe ukasangana nechimwe cheanotevera zviratidzo, dana chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • dzungu
  • kupera simba
  • kukurumidza kurova kwemoyo
  • kusvotwa
  • kurutsa
  • kuneta zvakanyanya
  • weti yakasviba
  • zvituru zvine mavara
  • kubuda ropa zvisina kujairika kana kupwanya
  • kushaya simba
  • kurasikirwa nenzara
  • kurwadziwa kumusoro kwepamusoro chikamu chedumbu
  • yero yeganda kana maziso
  • furu-kunge zviratidzo
  • mikoko
  • mapundu
  • kuvava
  • kunetseka kufema kana kumedza
  • kuzvimba kwechiso, huro, rurimi, miromo, maziso, maoko, tsoka, makumbo, kana makumbo ezasi
  • hoarseness
  • kusanzwisisika tsandanyama kurwadziwa, unyoro, kana kushaya simba

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari ekuongorora kuti uone mhinduro yako kune niacin.

Usati waita chero bvunzo yerabhoritari, udza chiremba wako uye vashandi veirabhoritari kuti uri kutora niacin.

Ingoshandisa iyo mhando uye mhando yeNiacin yakarairwa nachiremba wako. Usashandise imwe mhando ye niacin kana kushandura pakati pezvigadzirwa pasina kutaura nachiremba wako. Kana iwe ukachinjira kune rakasarudzika brand kana mhando yeNiacin, yako dose ingangoda kuchinjwa.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Niacor®
  • Niaspan®
  • Nicolar®
  • Slo-Niacin®
  • Simcor® (iine Niacin, Simvastatin)
  • Nicotinic asidhi

Ichi chigadzirwa chakapiswa hachisisiri pamusika. Dzimwe nzira dzinogona kuwanikwa.

Yekupedzisira Yakagadziridzwa - 02/15/2021

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