Clozapine

Zvemukati

• Usati watora clozapine,
• Clozapine inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera kana izvo zvakanyorwa mune ZVINOKOSHA ZVENYENZO kana ZVINOKOSHA ZVINONYANYA, daidza chiremba wako nekukurumidza:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

Clozapine inogona kukonzera chirwere chakakomba cheropa. Chiremba wako acharaira mamwe marabhoritari usati watanga kurapwa kwako, panguva yekurapwa kwako, uye kweanenge mavhiki mana mushure mekurapwa kwako. Chiremba wako anozoraira bvunzo bvunzo kamwe pavhiki pakutanga uye anogona kuraira bvunzo kashoma apo kurapwa kwako kunoenderera. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, dana chiremba wako nekukurumidza: kuneta zvakanyanya; kushaya simba; fivha, huro, chironda, kana zvimwe zviratidzo zvefuruwenza kana hutachiona; kujairika kusangana nekutsi kwemukadzi kubuda kana kuvaviwa; maronda mumuromo mako kana pahuro; maronda anotora nguva yakareba kuti apore; kurwadziwa kana kupisa paunenge uchiita weti; maronda kana kurwadziwa mukati kana kutenderedza yako rectal nzvimbo; kana kurwadziwa mudumbu.

Nekuda kwenjodzi nemushonga uyu, clozapine inowanikwa chete kuburikidza neyakaganhurirwa chirongwa chekugovera. Chirongwa chakagadzwa nevanogadzira clozapine kuve nechokwadi chekuti vanhu havatore clozapine pasina kuongororwa kwakakodzera kunodaidzwa kunzi Clozapine Risk Evaluation uye Mitigation Strategies (REMS) Chirongwa. Chiremba wako uye wemishonga wako anofanirwa kunyoreswa neClozapine REMS chirongwa, uye wemishonga wako haazopa mushonga wako kunze kwekunge iye agamuchira zvabuda mukuongororwa kweropa rako. Kumbira chiremba wako kuti uwane rumwe ruzivo nezvechirongwa ichi uye kuti unozogamuchira sei mushonga wako.

Clozapine inogona kukonzeresa. Udza chiremba wako kana iwe wakambobatwa nepfari. Usafambisa mota, shandisa michina, kushambira, kana kukwira paunenge uchitora clozapine, nekuti kana ukangoerekana warasikirwa nehana, unogona kuzvikuvadza kana vamwe. Kana iwe ukawana kubatwa, fonera chiremba wako nekukasira kana kuwana kurapwa kwekukurumidzira.

Clozapine inogona kukonzeresa myocarditis (kuzvimba kwemhasuru yemwoyo inogona kuva nengozi) kana cardiomyopathy (yakawedzeredzwa kana yakakora mhasuru yemwoyo inomisa moyo kupomba ropa zvakajairika). Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, dana chiremba wako nekukurumidza: kuneta zvakanyanya; dzihwa sezviratidzo; kunetseka kufema kana kufema nekukurumidza; kupindwa nechando; kurwadziwa muchipfuva; kana kutsanya, zvisina kujairika, kana kurova kurova kwemoyo.

Clozapine inogona kukonzera dzungu, huremu husina musoro, kana kupera simba paunomira, kunyanya paunotanga kuitora kana kana dosi rako richiwedzerwa. Udza chiremba wako kana iwe uine kana uine chirwere chemwoyo, kukundikana kwemoyo, kana kunonoka, kusagadzikana kwemwoyo kana kutora mishonga yekukwira kweropa. Uyezve udza chiremba wako kana uine kurutsa kwakanyanya kana manyoka kana zviratidzo zvekushaikwa kwemvura izvozvi, kana kana iwe ukava nezviratidzo izvi chero nguva panguva yekurapwa kwako. Chiremba wako angangotanga iwe pane yakaderera dosi yeclozapine uye zvishoma nezvishoma wedzera yako dosi kuti upe muviri wako nguva yekujaira kumushonga uye uderedze mukana wekuti iwe ugozoona iyi mhedzisiro Taura nachiremba wako kana ukasatora clozapine kwemazuva maviri kana kupfuura. Chiremba wako angangokuudza iwe kuti utangezve kurapwa kwako nedosi yakaderera ye clozapine.

Shandisa muVakwegura Vakuru:

Zvidzidzo zvakaratidza kuti vakuru vakura vane dementia (chirwere chehuropi chinokanganisa kugona kurangarira, kufunga zvakajeka, kutaurirana, uye kuita zviitiko zvezuva nezuva uye izvo zvinogona kukonzera shanduko mumafungire nehunhu) vanotora antipsychotic (mishonga yehurwere hwepfungwa) senge clozapine vane mukana wakawedzerwa wekufa panguva yekurapwa.

Clozapine haina kutenderwa neKudya neDrug Administration (FDA) yekurapa matambudziko ehunhu kune vakura vane chirwere chedementia. Taura nachiremba uyo akaraira clozapine kana iwe, nhengo yemhuri, kana mumwe munhu waunochengeta aine dementia uye ari kutora mushonga uyu. Kuti uwane rumwe ruzivo shanyira iyo FDA webhusaiti: http://www.fda.gov/Drugs

Clozapine inoshandiswa kurapa zviratidzo zvechichichiphrenia (chirwere chepfungwa chinokanganisa kufunga kana kujairika kufunga, kurasikirwa nefariro muhupenyu, uye kusimba kana kusanzwisisika manzwiro) muvanhu vasina kubatsirwa nemimwe mishonga kana vakaedza kuzviuraya uye vanogona kuedza kuzviuraya kana kuzvikuvadza zvakare. Clozapine iri mukirasi yemishonga inonzi atypical antipsychotic. Inoshanda nekushandura chiitiko cheimwe yakasarudzika zvinhu muuropi.

Clozapine inouya sehwendefa, piritsi inoparadzaniswa nemuromo (piritsi rinonyungudika nekukurumidza mumuromo), uye kumiswa kwemuromo (mvura) kutora nemuromo. Inowanzo kutorwa kamwe kana kaviri pazuva. Tora clozapine kwakatenderedza nguva imwechete (ma) mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora clozapine chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Usaedze kusundira pombi inoparadzaniswa nemuromo kuburikidza neyekuputira. Pane kudaro, shandisa maoko akaoma kuti ubvise mapepa acho. Pakarepo tora hwendefa uise parurimi rwako. Piritsi racho rinokurumidza kunyungudika uye rinogona kumedzwa nemate. Hapana mvura inodiwa kumedza mapiritsi anoparadzanisa.

Kuyera clozapine yekumiswa pamuromo, tevera nhanho idzi:

1. Ita shuwa kuti chivharo chakakamira pamuromo wekumisa mudziyo nekushandura chivharo kutenderera wachi (kurudyi). Zunza bhodhoro kumusoro uye pasi kwemaminitsi gumi usati washandisa.
2. Bvisa kapu yebhodhoro nekusvetera pasi pane chivharo, wobva waishandura uchienda kurudyi (kuruboshwe). Kekutanga nguva yaunovhura bhodhoro nyowani, pusha adhaputa mubhodhoro kusvikira kumusoro kweadapteri yakamisikidzwa kumusoro kwebhodhoro.
3. Kana yako dose iri 1 mL kana pasi, shandisa diki (1 mL) sirinji yemuromo. Kana yako dosi iri inopfuura 1 mL, shandisa hombe (9 mL) sirinji yemuromo.
4. Zadza sirinji yemuromo nemhepo nekudzosera kumashure plunger. Wobva waisa muromo wakavhurika wesirinji yemuromo muadapter. Pushira mweya wese kubva mujekiseni remuromo kupinda mubhodhoro nekusvetera pasi pane plunger.
5. Paunenge wakabata sirinji yemuromo panzvimbo, nyatso shandura bhodhoro rakatarisa pasi. Dhirowa mimwe yemishonga kunze kwebhodhoro mujekiseni remuromo nekukwevera kumashure pane plunger. Ive nekuchengera kuti urege kudhonza iyo plunger nzira yese yekubuda.
6. Iwe uchaona iwo mashoma mhepo padhuze nekuguma kweplunger mune yemuromo sirinji. Dhonza pombi kuitira kuti mushonga udzokere muhombodo uye mweya unonyangarika. Dhonza zvakare pa plunger kuti utore yako chaiyo mishonga dhizaini mune yemuromo sirinji.
7. Ndichiri wakabata sirinji yomumuromo muhombodo, nyatso chengetera bhodhoro kumusoro saka sirinji iri pamusoro. Bvisa sirinji yemuromo kubva mubhodhoro remutsipa adapter pasina kusundira pane plunger. Tora mishonga iyo mushure mekunge iwe waidhonza mukati memuromo wesirinji. Usagadzirire dosi uye uichengete mune sirinji yekushandisa gare gare.
8. Isa muromo wakavhurika wesirinji yemuromo mune rimwe divi remuromo wako. Nyatsovhara miromo yako kutenderedza sirinji yemuromo uye sundira pombi zvishoma nezvishoma mvura painopinda mumuromo mako. Medza mushonga zvishoma nezvishoma sezvo uchipinda mumuromo mako.
9. Siya iyo adapta muhombodo. Isa chivharo kumashure pabhodhoro wochichinjisa kurudyi (kurudyi) kuti urisimbise.
10. Shenesa sirinji yemuromo nemvura inodziya yemupombi mushure mekushandisa kwese. Zadza kapu nemvura woisa muromo wesirinji yemuromo mumvura iri mukapu. Dhonza zvakare pombi uye utore mvura mujekiseni remuromo. Pushira pombi kuti ubudise mvura musink kana mudziyo wakaparadzana kusvikira sirinji yemuromo yakachena. Bvumira iyo yemuromo sirinji mweya yakaoma uye rasa chero chasara mvura yekugeza.

Clozapine inodzora schizophrenia asi hairape. Zvinogona kutora mavhiki akati wandei kana kupfuura usati wanzwa kuzara kwakazara kwec clozapine. Ramba uchitora clozapine kunyangwe iwe uchinzwa zvakanaka. Usarega kutora clozapine usina kutaura nachiremba wako. Chiremba wako angangoda kudzikisa dosi yako zvishoma nezvishoma.

Mushonga uyu haufanire kupihwa mamwe mashandisiro; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora clozapine,

• udza chiremba wako uye wemishonga kana uri weergoria kune clozapine, chero mimwe mishonga, kana chero chinhu chinowanikwa mumahwendefa e clozapine. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura iwo akanyorwa mune CHINOKOSHA CHENYENZO chikamu uye chero cheanotevera: antihistamines senge diphenhydramine (Benadryl); mishonga inorwisa mabhakitiriya senge ciprofloxacin (Cipro) uye erythromycin (EES, E-Mycin, vamwe); benztropine (Cogentin); cimetidine (Tagamet); bupropion (Aplenzin, Wellbutrin, Zyban, muContrave); cyclobenzaprine (Amrix); escitalopram (Lexapro); mishonga yekushushikana, kuwedzerwa kweropa, kurwara nepfungwa, kurwara kwekufamba, kana kusvotwa; mishonga yekurova kwemoyo zvisina kujairika senge encainide, flecainide, propafenone (Rythmol), uye quinidine (muNuedexta); mishonga yekudzivirira pamuromo; mishonga yekubatwa kwakadai sa carbamazepine (Equetro, Tegretol, Teril, vamwe) kana phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane, muRifamate, muRifater); kunyaradza; inosarudza serotonin reuptake inhibitors (SSRIs) senge duloxetine (Cymbalta), fluoxetine (Prozac, Sarafem, Selfemra, vamwe), fluvoxamine (Luvox), paroxetine (Brisdelle, Paxil, Pexeva), uye sertraline (Zoloft); mapiritsi ekurara; terbinafine (Lamisil); uye zvinodzivirira. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• pamusoro pechimiro chakanyorwa muchikamu CHENYANZISO CHENYANZISO, udza chiremba wako kana iwe kana chero munhu mumhuri yako akambove nenguva yakareba yeQT (chinetso chemwoyo chisingawanzo chingakonzera kurova kwemoyo zvisina kujairika, kufenda, kana kufa kamwe kamwe) kana chirwere cheshuga. Udza chiremba wako kana uine kuzvimbirwa, kuda kusvotwa, kurutsa, kana kurwadziwa nemudumbu kana kusimuka. kana kana iwe kana wakambove nematambudziko neako weti system kana prostate (gland rekubereka rechirume); dyslipidemia (yakakwira cholesterol mazinga); akaoma mitezo ileus (mamiriro umo chikafu chisingakwanise kufamba nemuura); glaucoma; yakakwira kana yakaderera BP; kunetseka kuchengeta yako chiyero; kana moyo, itsvo, mapapu, kana chirwere chechiropa. Uyezve udza chiremba wako kana iwe wakambomira kutora mushonga wehurwere hwepfungwa nekuda kwemhedzisiro yakaipa.
• udza chiremba wako kana iwe uri nepamuviri, kunyanya kana iwe uri mumwedzi mishoma yapfuura yekubata kwako, kana kana iwe uronga kuve nepamuviri kana kuyamwisa. Kana iwe ukava nepamuviri uchitora clozapine, danaidza chiremba wako. Clozapine inogona kukonzera matambudziko muvacheche zvichitevera kuberekwa kana ikatorwa mukati memwedzi yekupedzisira yenhumbu.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora clozapine.
• iwe unofanirwa kuziva kuti doro rinogona kuwedzera kuhope dzinokonzerwa nemushonga uyu.
• udza chiremba wako kana ukashandisa zvigadzirwa zvefodya. Kusvuta fodya kunogona kudzora kushanda kwemushonga uyu.
• iwe unofanirwa kuziva kuti iwe unogona kusangana ne hyperglycemia (inowedzera mushuga yeropa rako) paunenge uchitora mushonga uyu, kunyangwe kana usati uine chirwere cheshuga. Kana iwe uine schizophrenia, iwe unowanzo kuve nechirwere cheshuga kupfuura vanhu vasina schizophrenia, uye kutora clozapine kana mishonga yakafanana kunogona kuwedzera njodzi iyi. Udza chiremba wako nekukasira kana uine chimwe chezviratidzo zvinotevera paunenge uchitora clozapine: nyota yakanyanya, kuita weti kakawanda, nzara yakanyanyisa, kuona kwakashata, kana kushaya simba. Zvakakosha kusheedza chiremba wako nekukurumidza kana uchinge uine chero cheizvi zviratidzo, nekuti shuga yepamusoro yeropa inogona kukonzera chirwere chakakomba chinonzi ketoacidosis. Ketoacidosis inogona kutyisidzira hupenyu kana ikasarapwa padanho rekutanga. Zviratidzo zve ketoacidosis zvinosanganisira: kuoma muromo, kuda kurutsa uye kurutsa, kufema kufema, mweya unonhuwira muchero, uye kudzikira kwekuziva.
• kana iwe uine phenylketonuria (PKU, chinzvimbo chakagarwa nhaka umo chikafu chakasarudzika chinofanira kuteverwa kudzivirira kudzora kwepfungwa), iwe unofanirwa kuziva kuti mahwendefa anoparadzaniswa nemuromo ane aspartame inoumba phenylalanine.

Taura nachiremba wako nezvekunwa zvinwiwa zvine caffeine paunenge uchitora mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Ukasuwa kutora clozapine kweanopfuura mazuva maviri, unofanirwa kufonera chiremba wako usati watora chero mumwe mushonga. Chiremba wako angangoda kutangazve yako mushonga pane yakaderera dosi.

Clozapine inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kutsimwaira
• dzungu, kunzwa kusagadzikana, kana kunetsekana nekuchengetedza mwero wako
• kuwedzera salivation
• muromo wakaoma
• kusagadzikana
• musoro

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera kana izvo zvakanyorwa mune ZVINOKOSHA ZVENYENZO kana ZVINOKOSHA ZVINONYANYA, daidza chiremba wako nekukurumidza:

• kupatirwa; kusvotwa; dumbu kuzvimba kana kurwadziwa; kana kurutsa
• kukwazisana maoko ausingakwanise kudzora
• kufenda
• kudonha
• kunetseka kuita weti kana kurasikirwa kwedundira kudzora
• kuvhiringidzika
• shanduko pane zvakaratidzwa
• kuzununguka
• kuomarara kwetsandanyama
• vangadikitira
• shanduko mumaitiro
• kubuda ropa zvisina kujairika kana kupwanya
• kurasikirwa nenzara
• kugumbuka mudumbu
• yero yeganda kana maziso
• kurwadziwa kumusoro kwepamusoro chikamu chedumbu
• kushaya simba

Clozapine inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nechiedza uye kupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Usaisa mufiriji kana kuisa chando kumiswa kwemuromo.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

• dzungu
• kufenda
• kunonoka kufema
• shanduka mukurova kwemoyo
• kurasikirwa kwekuziva

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune clozapine.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Clozaril^®
• FazaClo^® ODT
• Versacloz^®