Saquinavir

Zvemukati

• Usati watora saquinavir,
• Saquinavir inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

Saquinavir inoshandiswa pamwe chete ne ritonavir (Norvir) nemimwe mishonga yekurapa hutachiona hwehutachiona hwehutachiona hweHIV. Saquinavir iri mukirasi yemishonga inonzi protease inhibitors. Inoshanda nekuderedza huwandu hweHIV muropa. Kunyangwe saquinavir isingarape HIV, inogona kudzikisira mukana wako wekuwana immunodeficiency syndrome (AIDS) nezvirwere zvine chekuita neHIV zvakadai sehutachiona hwakakomba kana gomarara. Kutora mishonga iyi pamwe nekuita bonde rakachengeteka uye nekuchinja dzimwe mararamire kunogona kudzikisa njodzi yekutapurira utachiona hweHIV kune vamwe vanhu.

Saquinavir inouya se capsule uye piritsi yekutora nemuromo. Inowanzo kutorwa panguva imwechete se ritonavir (Norvir) kaviri pazuva mukati maawa maviri mushure mekudya kuzere. Zvinogona kuve nyore kurangarira kutora saquinavir kana iwe ukaitora pamwe nekudya. Tora saquinavir kwakatenderedza nguva dzakafanana mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora saquinavir chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsvage, kana kuapwanya.

Kana iwe usingakwanise kumedza iyo capsule izere, unogona kutora saquinavir nekuvhura kapuleti uye nekusanganisa zvirimo neshuga manyuchi, sorbitol, kana jam. Kugadzirira dhosi rega rega, wedzera 3 mashupuni (15 mL) yeshuga manyuchi, sorbitol, kana jam kune mudziyo usina chinhu. Vhura saquinavir capsule uye wedzera zvirimo mumudziyo. Simbisai musanganiswa kwemasekondi makumi matatu kusvika makumi matanhatu. Kana iwe waishandisa sirasi inotonhora, sorbitol, kana jam, mirira kuti musanganiswa uuye kutembiricha yemukati usati wadya. Ive neshuwa yekudya iyo yose musanganiswa kuitira kuti ugamuchire iwo muzere wedosi.

Ramba uchitora saquinavir kunyangwe uchinzwa mushe. Usarega kutora saquinavir usina kutaura nachiremba wako. Kana ukarasikirwa nemadhizaini, tora zvishoma pane yakatarwa dosi kana kurega kutora saquinavir, mamiriro ako anogona kuzove akaoma kurapa.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Mishonga Inotungamira) paunotanga kurapwa ne saquinavir uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Saquinavir dzimwe nguva inoshandiswa ne ritonavir (Norvir) nemimwe mishonga kubatsira kudzivirira hutachiona muvashandi vezvehutano kana vamwe vanhu vakafumurwa neHIV. Taura nachiremba wako nezve njodzi dzekutora mushonga uyu kune ako mamiriro.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora saquinavir,

• udza chiremba wako uye wemishonga kana uri weergoria kune saquinavir, chero mimwe mishonga, lactose, kana chero chimwe chezvinhu zvinosanganiswa mu saquinavir capsules kana mapiritsi. Chiremba wako anogona kukuudza kuti usatore saquinavir. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako kana iwe uri kutora chero einotevera mishonga: alfuzosin (Uroxatral); atazanavir (Reyataz, muEvotaz); clarithromycin (Biaxin, muPrevpac); clozapine (Clozaril, Fazaclo, Versacloz); dasatinib (Sprycel); ergot mishonga yakadai se dihydroergotamine (DHE 45, Migranal), ergoloid mesylates (Hydergine), ergonovine (Ergotrate), ergotamine (Ergomar, muCafergot, muMigergot, vamwe), uye methylergonovine (Methergine); erythromycin (EES, E-mycin, Erythrocin, vamwe); halofantrine; haloperidol (Haldol); mimwe mishonga yekushaya moyo zvisina kujairika senge amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), flecainide (Tambocor), lidocaine (Xylocaine), propafenone (Rhythmol), uye quinidine (muNuedexta); lovastatin (Altoprev); lurasidone (Latuda); mishonga yekurwara nepfungwa uye kuda kurutsa senge chlorpromazine, uye thioridazine; midazolam nemuromo; pentamidine (Nebupent, Pentam); pimozide (Orap); quinine (Qualaquin); rifampin (Rifadin, Rimactane, muRifamate, Rifater); sildenafil (chete Revatio brand inoshandiswa pachirwere chemapapu); simvastatin (Zocor, Flolopid, muVytorin); sunatinib (Sutent); tacrolimus (Astagraf XL, Envarsus XR, Prograf); trazodone; triazolam (Halcion); kana ziprasidone (Geodon). Uyezve udza chiremba wako kana wemishonga kana iwe uri kutora rilpivirine (Edurant, muJucuca, Odefsey, Complera) kana kana warega kuitora mukati memavhiki maviri apfuura. Chiremba wako anogona kukuudza kuti usatora saquinavir kana iwe uri kutora imwe kana yakawanda yemishonga iyi.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: anticoagulants ('blood thinner') senge warfarin (Coumadin, Jantoven); antifungals senge itraconazole (Onmel, Sporanox) uye ketoconazole benzodiazepines senge alprazolam (Xanax), clorazepate (Gen-Xene, Tranxene), diazepam (Diastat, Valium), uye flurazepam; beta blockers senge atenolol (Tenormin, muTenoretic), labetalol (Trandate), metoprolol (Lopressor, Toprol XL, muDutoprol, muLoressor HCT), nadolol (Corgard, muCorzide), uye propranolol (Hemangeol, Inderal, Innopran); bosentan (Tracleer); calcium chiteshi blockers senge amlodipine (Norvasc, muCaduet, Lotrel, vamwe), diltiazem (Cardizem, Cartia, Tiazac, vamwe), felodipine, isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab CR, Procardia), nimodipine (Nymalize ), nisoldipine (Sular), uye verapamil (Calan, Verelan, muTarka); mamwe cholesterol-ekudzikisa mishonga (statins) senge atorvastatin (Lipitor, muCaduet); cobicistat (Tybost, muEvotaz, Genvoya, Prezcobix, uye Stribild); corticosteroids senge betamethasone, budesonide (Entocort, Pulmicort, Uceris, muSymbicort), ciclesonide (Alvesco, Zetonna, Omnaris), dexamethasone, fluticasone (Arnuity Ellipta, Flonase, Flovent, muAdvair, vamwe), methylprednisone, Asmana ), prednisone (Rayos), uye triamcinolone (Kenalog); colchicine (Colcrys, Mitigare); digoxin (Lanoxin); fentanyl (Abstral, Actiq, Duragesic, vamwe); mamwe immunosuppressants akadai cyclosporine (Gengraf, Neoral, Sandimmune), uye sirolimus (Rapamune); mishonga yekurapa HIV kana AIDS inosanganisira indinavir (Crixivan), lopinavir ne ritonavir (Kaletra), maraviroc (Selzentry), nelfinavir (Viracept), kana tipranavir ine ritonavir (Aptivus); mimwe mishonga yekurova kwemoyo zvisina kujairika senge ibutilide (Corvert), uye sotalol (Betapace, Sorine, Sotylize); mishonga yekurapa pfari dzakadai secarbamazepine (Carbatrol, Epitol, Tegretol, vamwe), phenytoin (Dilantin, Phenytek), uye phenobarbital; methadone (Dolophine, Methadose); nefazodone; omeprazole (Prilosec, muYosprela, Zegerid); zvimwe phosphodiesterase (PDE5) inhibitors sildenafil (Viagra), tadalafil (Adcirca, Cialis), uye vardenafil (Levitra, Staxyn); quetiapine (Seroquel); quinupristin uye dalfopristin (Synercid); rifabutin (Mycobutin); salmeterol (Serevent, muAdvair); uye mamwe tricyclic antidepressants anosanganisira amitriptyline, clomipramine (Anafranil), imipramine (Surmontil, Tofranil), uye maprotiline. Mimwe mishonga inogona kupindirana nesaquinavir, saka ive shuwa kuudza chiremba wako uye wemishonga nezve yese mishonga yauri kutora, kunyangwe iyo isingaonekwe pane ino runyorwa. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemishonga zvauri kutora kana kuronga kutora, kunyanya St. John's wort, uye makapisi egariki.
• udza chiremba wako kana iwe uchinwa kana wakambonwa doro rakawanda, uye kana iwe kana chero mumwe munhu mumhuri yako akambove kana akambove nechirwere cheshuga. Uyezve udza chiremba wako kana iwe wakambove nekurova kwemoyo zvisina kujairika, cholesterol yakawanda kana triglycerides (mafuta muropa); hemophilia (kubuda ropa kusagadzikana); mamiriro umo muviri usingakwanise kuburitsa lactase yakakwana kana kusakwanisa kushivirira lactose, kana moyo kana chirwere cheitsvo.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Kana iwe ukava nepamuviri uchitora saquinavir, fonera chiremba wako. Iwe haufanire kuyamwa kana uine hutachiona hweHIV kana uri kutora saquinavir.
• iwe unofanirwa kuziva kuti saquinavir inogona kudzikisira kushanda kwemahomoni ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, kana majekiseni). Taura nachiremba wako nezve kushandisa imwe nzira yekudzivirira kuberekwa.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti uri kutora saquinavir.
• iwe unofanirwa kuziva kuti mafuta emuviri wako anogona kuwedzera kana kuenda kunzvimbo dzakasiyana dzemuviri wako, senge rako repamusoro musana, mutsipa ('' nyati hump ''), mazamu, uye kutenderedza dumbu rako. Iwe unogona kucherechedza kurasikirwa kwemafuta emuviri kubva kumeso kwako, makumbo, uye maoko.
• iwe unofanirwa kuziva kuti iwe unogona kusangana ne hyperglycemia (inowedzera mushuga yeropa rako) paunenge uchitora mushonga uyu, kunyangwe kana usati uine chirwere cheshuga. Udza chiremba wako nekukasira kana uine chimwe chezviratidzo zvinotevera paunenge uchitora saquinavir: nyota yakanyanya, kuita weti kakawanda, nzara yakanyanyisa, kuona kwakashata, kana kushaya simba. Zvakakosha kusheedza chiremba wako nekukurumidza kana uchinge uine chero cheizvi zviratidzo, nekuti shuga yepamusoro yeropa isingarapwe inogona kukonzera chirwere chakakomba chinonzi ketoacidosis. Ketoacidosis inogona kutyisidzira hupenyu kana ikasarapwa padanho rekutanga. Zviratidzo zve ketoacidosis zvinosanganisira kuoma muromo, kuda kurutsa uye kurutsa, kufema kwekufema, mweya unonhuwira muchero, uye kudzikira kwekuziva.
• Unofanirwa kuziva kuti paunenge uchinwa mishonga yekurapa hutachiona hweHIV, immune system yako inogona kusimba uye yotanga kurwisa zvimwe hutachiona zvaive mumuviri wako kana kukonzera zvimwe zviitiko kuti zviitike. Izvi zvinogona kukonzera iwe kukudziridza zviratidzo zveawo hutachiona kana mamiriro. Kana uine zviratidzo zvitsva kana zvichikura mushure mekutanga kurapwa ne saquinavir, ita chokwadi chekuudza chiremba wako.

Taura nachiremba wako nezve kudya mazambiringa uye kunwa jisi remuzambiringa paunenge uchitora mushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Saquinavir inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• manyoka
• kurwadziwa nemudumbu
• kusvotwa
• kurutsa
• kuvimbiswa
• kuneta
• kurwadziwa shure
• miromo yakaoma kana ganda
• kupindwa nechando

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• mapundu, kuchenjera, kuzvimba kwemaziso, kumeso, muromo, huro, kana miromo, kunetseka kufema kana kumedza
• kuputika kana kubvisa ganda
• yero yeganda kana maziso, kurasikirwa kwechido, dzihwa sezviratidzo, kuneta kwakanyanya, yakasviba weti weti, akajeka mavara zvituru, kurwadziwa mune yekumusoro kurudyi chikamu chedumbu
• dzungu, huremu husina musoro, kunonoka, kusajairika, kana kurova kurova kwemoyo, kufenda

Saquinavir inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

• kurwadziwa pahuro

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira kumwe kuongorora kwelebhu usati uye panguva yekurapwa kwako kuti utarise mhinduro yemuviri wako kune saquinavir. Chiremba wako anogona zvakare kuraira electrocardiogram (ECG; bvunzo inoyera chiitiko chemagetsi mumoyo) usati uye panguva yekurapa kwako.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Invirase^®