Kupona Mitengo uye Maonero ePacute Myeloid Leukemia (AML)

Zvemukati

• Ndeapi matanho ekupona eAML?
• Vana vane AML
• Ndezvipi zvinhu zvinokanganisa kupona kwehuwandu?
• Zera rinoita sei pamwero wekupona?
• Ndeipi mhedzisiro iyo AML mhando ine pamwero wekupona?
• Mhedzisiro yekurapa ine chekuita nezvekupona mwero?
• Munhu angatsvage sei rutsigiro?
• Bvunza mibvunzo
• Tsvaga masangano anopa rutsigiro
• Joinha boka rekutsigira
• Svitsa kune shamwari uye mhuri
• Tsvaga nzira dzinonakidza dzekudzora kushushikana

Chii chinonzi acute myeloid leukemia (AML)?

Acute myeloid leukemia, kana AML, mhando yekenza inobata mwongo uye neropa. Inozivikanwa nemazita akasiyana siyana, anosanganisira acute myelogenous leukemia and acute non-lymphocytic leukemia. AML ndiyo yechipiri inonyanya kuzivikanwa leukemia mhando muvanhu vakuru.

Vanachiremba vanodana AML "acute" nekuti mamiriro acho anogona kufambira mberi nekukurumidza. Izwi rekuti "leukemia" rinoreva kenza yemongo wemapfupa nemasero eropa. Izwi rekuti myeloid, kana myelogenous, rinoreva iyo sero rudzi iyo yainoita.

Myeloid masero anotungamira kune mamwe masero eropa. Kazhinji aya maseru anoenderera mberi achikura kuita masero matsvuku eropa (RBCs), maplatelet, uye akasarudzika marudzi chena eropa masero (WBCs). Asi mu AML, ivo havagone kukura zvakajairika.

Kana munhu aine AML, masero avo emyeroid anochinja uye oita chirwere che leukemic. Aya maseru haashande sezvinoita maseru akajairika. Vanogona kuchengetedza muviri kubva mukugadzira akajairika, maseru ane hutano.

Pakupedzisira, munhu anotanga kushaya maRBC anotakura oxygen, maplatelet anodzivirira kubuda ropa nyore, uye maWBCs anodzivirira muviri kubva kuzvirwere. Izvi zvinodaro nekuti muviri wavo wakabatikana kugadzira leukemic blast maseru.

Mhedzisiro yacho inogona kuuraya. Nekudaro, kune vanhu vazhinji, AML chirwere chinorapika.

Ndeapi matanho ekupona eAML?

Kufambira mberi mukurapa kenza uye vanachiremba 'kunzwisisa kwechirwere kunoreva kuti vanhu vazhinji uye vazhinji vanopona mamiriro acho gore rega.

Gore rega rega vanachiremba vanoongorora vanhu vanofungidzirwa kuti vanosvika 19,520 muUnited States vane AML. Inofungidzirwa kuti zviuru gumi nemazana matanhatu nemakumi matanhatu vakafa zvinoitika pagore nekuda kwechirwere.

Vanhu vazhinji vane AML vanogamuchira chemotherapy kurapwa. Iyi mishonga inokurumidza kuuraya masero akapatsanuka, senge cancer maseru. Chemotherapy inogona kutungamira mukuregererwa, zvinoreva kuti munhu haana zviratidzo zvechirwere uye masero eropa rake ari mune yakajairwa renji.

Vanenge makumi mapfumbamwe muzana muzana vevanhu vane AML mhando inozivikanwa seacute promyelocytic leukemia (APL) vanozoenda mukuregererwa mushure me "induction" (yekutanga kutenderera) chemo. Izvi zviri maererano neAmerican Cancer Society (ACS). Kune mamwe akawanda marudzi e AML, iyo yekuregererwa mwero iri kutenderera 67 muzana.

Ivo vakura kupfuura zera makumi matanhatu havawanzo kupindura kurapwa futi, iine hafu yavo vanoenda mukuregererwa mushure mekunyorwa.

Vamwe vanhu vanoenda mukuregererwa vanogara mukuregererwa. Zvakadaro, kune vazhinji, AML inogona kudzoka nekufamba kwenguva.

Makore mashanu ekupona kwe AML ndeye 27.4 muzana, maererano neNational Cancer Institute (NCI). Izvi zvinoreva kuti pamakumi ezviuru evaAmerica vanogara neAML, inofungidzirwa kuti 27.4 muzana vachiri kurarama makore mashanu mushure mekuongororwa kwavo.

Vana vane AML

Muzhinji, vana vane AML vanoonekwa sengozi yakaderera pane vanhu vakuru. Dzakakomberedza 85 kusvika 90 muzana yevana vane AML vanoenda mukuregererwa mushure mekunyorwa, sekureva kweAmerican Cancer Society. AML inodzoka mune dzimwe nguva.

Makore mashanu-ekupona-mwero wevana vane AML ndeye 60 kusvika 70 muzana.

Ndezvipi zvinhu zvinokanganisa kupona kwehuwandu?

Maonero uye kufungidzira kwe AML zvinosiyana zvakanyanya. Vanachiremba vanofunga zvinhu zvakawanda kana vachipa mumwe munhu kufungidzira, senge zera remunhu kana mhando ye AML.

Zvizhinji zvacho zvakavakirwa pamhedzisiro uye kuongororwa kweropa kuongororwa, zvidzidzo zvekufungidzira, bvunzo dzecerebrospinal fluid (CSF), uye mapfupa emongo.

Vamwe vanhu vane fungidziro yakaipa vanorarama makore mazhinji kupfuura izvo zvinofungidzirwa nachiremba apo vamwe vangasararama kwenguva yakareba.

Zera rinoita sei pamwero wekupona?

Iyo yepakati zera yemunhu anoonekwa aine AML ane makore makumi matanhatu nemasere ekuberekwa.

Zera rinogona kuve chinhu chakakosha mukugadzirisa kurapwa kweAML. Vanachiremba vanoziva kuti mwero wekupona weavo vanoonekwa vaine AML iri kuvimbisa zvakanyanya kune vanhu vari pasi pemakore makumi matanhatu.

Izvi zvinogona kuve nekuda kwezvikonzero zvinoverengeka. Vamwe vanhu vane makore anodarika makumi matanhatu vanogona kunge vaine chirwere chisingaperi kana vangave vasina hutano hwakanaka. Izvi zvinogona kuita kuti zviomere miviri yavo kubata yakasimba chemotherapy mishonga uye mamwe marapirwo ekenza anosangana neAML.

Uyezve, vakuru vakuru vazhinji vane AML havagashi kurapwa kwechiitiko ichi.

Chidzidzo chegore ra2015 chakawana kuti chete makumi mana muzana yevanhu makumi matanhatu nemasere zvichikwira vakagamuchira chemotherapy mukati memwedzi mitatu yekuongororwa. Kunyangwe paine misiyano yemhinduro yekurapa pakati pemapoka emazera akasiyana (kana macohort), huwandu hwekupona kwevanhu pakati pemakore makumi matanhatu nematanhatu nematanhatu nematanhatu hwave nani pamakumi matatu emakore apfuura, sekureva kwechidzidzo cha2011

Ndeipi mhedzisiro iyo AML mhando ine pamwero wekupona?

Vanachiremba vanowanzo rongedza dzakasiyana mhando dze AML nemasero avo masero. Mamwe maseru ekuchinja mhando anozivikanwa kunge anoteerera kurapwa. Mienzaniso inosanganisira mutated CEBPA uye inv (16) CBFB-MYH11 masero.

Dzimwe shanduko dzemasero dzinogona kunge dzisingarapike. Mienzaniso inosanganisira del (5q) uye inv (3) RPN1-EVI1. Yako oncologist inokuudza iwe rudzii kana mhando dzesero shanduko iwe yaungave iwe.

Mhedzisiro yekurapa ine chekuita nezvekupona mwero?

Vamwe vanhu vanopindura zvirinani pakurapwa kupfuura vamwe. Kana munhu akawana chemotherapy kurapwa uye gomarara ravo risingadzoke mukati memakore mashanu, vanowanzoonekwa sevanorapwa.

Kana kenza yemunhu ikadzoka kana kusapindura kurapwa zvachose, mhedzisiro yavo yekurapa haina kunaka.

Munhu angatsvage sei rutsigiro?

Kunyangwe kufungidzira, kuongororwa kwe AML kunogona kugadzira manzwiro ekutya, kushushikana, uye kusava nechokwadi. Unogona kunge usina chokwadi kwekuenda kana kutsvaga rutsigiro.

Kuongororwa kenza kunopa mukana wekuti iwe ukure padhuze nevari padyo newe uye woongorora kuti ungararama sei hupenyu hwaunofarira.

Heano matipi mashoma ekukubatsira kufamba ichi kuongororwa uye kurapwa.

Bvunza mibvunzo

Zvakakosha kuti iwe unzwisise mamiriro ako. Kana paine chimwe chinhu chausina chokwadi nacho maererano nehutano hwako, kurapwa, kana kufungidzira, bvunza chiremba wako.

Mienzaniso yemibvunzo yekubvunza inogona kusanganisira "Ndeapi marapirwo andinogona kurapwa?" uye "Chii chandingaite kudzivirira AML kudzoka?"

Tsvaga masangano anopa rutsigiro

Masangano akaita seAmerican Cancer Society (ACS) anopa akawanda mabasa ekutsigira.

Izvi zvinosanganisira kuronga kutasva kuenda kunorapwa uye kukubatsira iwe kuwana vashandi vanobatsira, senge vezvekudya kana vevashandi vezvemagariro.

Joinha boka rekutsigira

Mapoka ekutsigira inzira yakanaka kwazvo yekusangana nevanhu vari kupfuura nemanzwiro akafanana newe. Kuona kubudirira uye pfungwa dzevamwe zvinogona kubatsira iwe kuziva kuti hausi wega.

Mukuwedzera kune zviwanikwa zvakaita seAACS neLLS, wako oncologist kana chipatara chemuno anogona kupa mapoka ekutsigira.

Svitsa kune shamwari uye mhuri

Shamwari zhinji uye nhengo dzemhuri dzichada kubatsira. Regai vape chikafu kuburikidza neshumiro yakadai seKudya Chitima kana kungoteerera kune zvaunonetseka. Kuvhurira vamwe kunogona kukubatsira kuti urambe uine chimiro chendangariro.

Tsvaga nzira dzinonakidza dzekudzora kushushikana

Kune akawanda maresitorendi ekuti usunungure kunetseka uye kunetseka muhupenyu hwako. Kufungisisa kana kuchengeta bhuku kana blog mienzaniso mishoma. Uyezve, ivo vanodhura zvishoma kwazvo kutora uye kuenderera.

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