Ajovy (fremanezumab-vfrm)

Zvemukati

• Chii chinonzi Ajovy?
• Rudzi rutsva rwemushonga
• Kubudirira
• Ajovy generic
• Ajovy anoshandisa
• Ajovy yemigraine musoro
• Kubudirira kwemigraine misoro
• Ajovy mhedzisiro
• Zvimwe zvakajairika mhedzisiro
• Yakakomba mhedzisiro
• Allergic reaction
• Yakareba-nguva mhedzisiro
• Dzimwe nzira dzeAjovy
• CGRP vanopikisa
• Ajovy vs. mimwe mishonga
• Ajovy vs. Aimovig
• Ajovy vs. Emgality
• Ajovy vs. Botox
• Ajovy mutengo
• Rubatsiro rwemari
• Ajovy chipimo chemushonga
• Mafomu emishonga uye simba
• Dosage for migraine headache kudzivirira
• Ko kana ndikapotsa dosi?
• Ndichada here kushandisa mushonga uyu kwenguva refu?
• Maitiro ekutora Ajovy
• Jekiseni
• Nguva
• Kutora Ajovy nechikafu
• Anoshanda sei Ajovy
• Zvinotora nguva yakareba sei kuti zvishande?
• Ajovy nedoro
• Ajovy kudyidzana
• Ajovy uye nhumbu
• Ajovy uye kuyamwisa
• Mibvunzo yakajairika nezve Ajovy
• Anogona here Ajovy kurapa migraine musoro?
• Ajovy akasiyana papi nemimwe migraine zvinodhaka?
• Ko Ajovy anorapa migraine musoro here?
• Kana ndikatora Ajovy, ndinogona here kurega kutora yangu mimwe mishonga yekudzivirira?
• Ajovy kudarika
• Ovhadhozi zviratidzo
• Zvekuita kana ovhadhozi
• Ajovy yambiro
• Ajovy kupera

Chii chinonzi Ajovy?

Ajovy izita rezita remushonga mushonga unoshandiswa kudzivirira migraine kutemwa nemusoro muvakuru. Iyo inouya seyakagadzirirwa sirinji. Unogona kuzvibaya Ajovy, kana kugamuchira majekiseni eAjovy kubva kune anopa hutano muhofisi yechiremba wako. Ajovy inogona kuiswa jekiseni pamwedzi kana pamakota (kamwe chete pamwedzi mitatu).

Ajovy ine mushonga fremanezumab, inova monoclonal antibody. Monoclonal antibody imhando yemushonga iyo inogadzirwa kubva kumasero ezvirwere zvemuviri. Inoshanda nekudzivirira mamwe emapuroteni emuviri wako kuti asashande. Ajovy inogona kushandiswa kudzivirira zvese episodic uye chisingaperi migraine misoro.

Rudzi rutsva rwemushonga

Ajovy chikamu chekirasi nyowani yemishonga inozivikanwa secalcitonin gene-inoenderana peptide (CGRP) vanopikisa. Iyi mishonga ndiyo yekutanga mishonga yakagadzirirwa kudzivirira migraine misoro.

Chikafu neDrug Administration (FDA) yakatendera Ajovy munaGunyana 2018. Ajovy waive mushonga wechipiri muCGRP antagonist kirasi iyo FDA yakabvumidza kubatsira kudzivirira migraine kutemwa nemusoro.

Kune zvekare mamwe maviri maCGRP anopikisa aripo. Iyi mishonga inonzi Emgality (galcanezumab) uye Aimovig (erenumab). Kune wechina CGRP anopikisa anonzi eptinezumab iri kudzidzawo. Inotarisirwa kugamuchirwa neDFA mune ramangwana.

Kubudirira

Kuti udzidze nezve kushanda kweAjovy, ona iyo "Ajovy inoshandisa" chikamu pazasi.

Ajovy generic

Ajovy inowanikwa chete sezita-zita mushonga. Haisi ikozvino inowanikwa mune generic fomu.

Ajovy ine iyo zvinodhaka fremanezumab, iyo inonziwo fremanezumab-vfrm. Icho chikonzero "-vfrm" chinoonekwa panopera zita kuratidza kuti mushonga uyu wakasiyana nemishonga yakafanana iyo inogona kugadzirwa mune ramangwana. Mamwe ma monoclonal antibodies anotumidzwa nenzira yakafanana.

Ajovy anoshandisa

IU.S. Food and Drug Administration (FDA) inobvumidza mishonga yemishonga yakadai saAjovy kurapa kana kudzivirira mamwe mamiriro.

Ajovy yemigraine musoro

Iyo FDA yakabvumidza Ajovy kubatsira kudzivirira migraine kutemwa nemusoro muvakuru. Iyi misoro yakanyanya. Ichowo chiratidzo chikuru chemigraine, inova chirwere chetsinga. Kunzwisisa kuchiedza uye kurira, kuda kurutsa, kurutsa, uye kunetseka kutaura zvimwe zviratidzo zvinogona kuitika nemusoro wemusoro.

Ajovy anotenderwa kudzivirira ese asingagumi migraine kutemwa nemusoro uye episodic migraine musoro. Sangano reInternational Headache Society rinoti vanhu vane episodic migraine misoro vanoona vashoma pane gumi nemashanu migraine kana mazuva emusoro mwedzi wega wega. Vanhu vane chirwere chisingaperi chemigraine, kune rimwe divi, vanoona 15 kana anopfuura mazuva emusoro mwedzi wega wega pamusoro pemwedzi mitatu. Uye zvirinani zvisere zvemazuva ano migraine mazuva.

Kubudirira kwemigraine misoro

Ajovy akawanikwa achibudirira mukudzivirira migraine kutemwa nemusoro. Kuti uwane ruzivo rwekuti Ajovy akaitisa sei muzvidzidzo zvekiriniki, ona mushonga wekupa mushonga ruzivo.

IAmerican Headache Society inokurudzira kushandiswa kweAjovy kudzivirira migraine kutemwa nemusoro muvanhu vakuru vasingakwanise kudzikisa huwandu hwemazuva emigraine zvakakwana nemimwe mishonga. Inokurudzirawo Ajovy kune vanhu vasingakwanise kutora mimwe mishonga yekudzivirira migraine nekuda kwemhedzisiro kana kusangana kwemishonga.

Ajovy mhedzisiro

Ajovy inogona kukonzera manyoro kana zvakakomba mhedzisiro. Iri rinotevera runyorwa rine mamwe akakosha mhedzisiro mhedzisiro anogona kuitika uchitora Ajovy. Rondedzero iyi haisanganisi zvese zvinokanganisa mhedzisiro.

Kuti uwane rumwe ruzivo nezve zvingangoitika mhedzisiro yeAjovy, kana matipi ekuti ungagadzirise sei zvinokanganisa mhedzisiro, taura nachiremba wako kana wemishonga.

Zvimwe zvakajairika mhedzisiro

Iyo yakajairika mhedzisiro mhedzisiro yeAjovy ndeye jekiseni saiti saiti. Izvi zvinogona kusanganisira zvinotevera mhedzisiro pane saiti iwe yaunobaya mushonga.

• kutsvuka
• kuvava
• kurwadziwa
• unyoro

Injection saiti saiti kazhinji haina kuomarara kana kusingaperi. Mazhinji emhedzisiro iyi anogona kunyangarika mukati memazuva mashoma kana mavhiki mashoma. Taura nachiremba wako kana wemishonga kana yako mhedzisiro yakaipa zvakanyanya kana kuti isingaendi.

Yakakomba mhedzisiro

Hazvina kujairika kuve nematambudziko akakomba kubva kuna Ajovy, asi zvinogoneka. Iyo huru yakakomba mhedzisiro mhedzisiro yeAjovy ndeye yakakomba yegerger reaction kune mushonga. Ona pazasi kuti uwane ruzivo.

Allergic reaction

Sezvo nemishonga yakawanda, vamwe vanhu vanogona kusangana neanogadzirisa maitiro mushure mekunge vatora Ajovy. Zviratidzo zvehunyoro hweergic reaction zvinogona kusanganisira:

• kuvava
• kuputika kweganda
• kuburitsa (kudziya uye kutsvuka mukati meganda rako)

Kuwedzera kweanogarisana neAjovy kushoma. Zviratidzo zvinogona kuitika zvehutachiona hwakanyanya zvinosanganisira:

• kuzvimba kwerurimi rwako, muromo, kana huro
• angioedema (kuzvimba pasi peganda rako, kazhinji mumaziso ako, miromo, maoko, kana tsoka)
• kunetseka kufema

Kana iwe uine chakakomba chemaergic reaction kuna Ajovy, fonera chiremba wako ipapo ipapo. Kana zviratidzo zvako zvichinzwa kutyisidzira hupenyu kana iwe uchifunga kuti une chirwere chekukurumidzira, fonera 911.

Yakareba-nguva mhedzisiro

Ajovy mushonga uchangobva kugamuchirwa mukirasi nyowani yemishonga. Nekuda kweizvozvo, kune kushomeka kushoma kwenguva refu kwekuchengetedzwa kwaAjovy, uye zvishoma zvinozivikanwa nezve ayo marefu-mhedzisiro mhedzisiro. Yakarebesa kiriniki yekudzidza (PS30) yeAjovy yakatora gore rimwe, uye vanhu vari muchidzidzo havana kuzivisa chero zvakakomba mhedzisiro.

Jekiseni saiti yekupindura ndiyo yaive yakajairika mhedzisiro mhedzisiro yakataurwa mune yegore-refu kudzidza. Vanhu vakataura zvinotevera mhedzisiro munzvimbo yakapihwa jekiseni:

• kurwadziwa
• kutsvuka
• kubuda ropa
• kuvava
• ganda rinoputika kana rakasimudzwa

Dzimwe nzira dzeAjovy

Kune mimwe mishonga iripo inogona kubatsira kudzivirira migraine kutemwa nemusoro. Zvimwe zvinogona kunge zviri nani kwauri kune vamwe. Kana iwe uchida kutsvaga imwe nzira yeAjovy, taura nachiremba wako. Vanogona kukubatsira iwe kudzidza nezvemimwe mishonga ingave yakakunakira iwe.

Heano mimwe mienzaniso yemimwe mishonga iyo FDA yakabvumidza kubatsira kudzivirira migraine misoro:

• iyo beta-blocker propranolol (Inderal, Inderal LA)
• iyo neurotoxin onabotulinumtoxinA (Botox)
• mimwe mishonga yekubvuta, yakadai se divalproex sodium (Depakote) kana topiramate (Topamax, Trokendi XR)
• imwe calcitonin peptide inoenderana negene (CGRP) vanopikisa: erenumab-aooe (Aimovig) uye galcanezumab-gnlm (Emgality)

Heano mimwe mimwe mienzaniso yemamwe madhiragi ayo anogona kushandiswa kure-chitambi chekudzivirira musoro wemusoro.

• mimwe mishonga yekubata, yakadai sevalproate sodium
• zvimwe zvinodhaka, zvakadai seamitriptyline kana venlafaxine (Effexor XR)
• vamwe beta-blockers, senge metoprolol (Lopressor, Toprol XL) kana atenolol (Tenormin)

CGRP vanopikisa

Ajovy imhando nyowani yemushonga inonzi calcitonin gene-related peptide (CGRP) antagonist. Muna 2018, FDA yakabvumira Ajovy kudzivirira migraine misoro, pamwe nevamwe vaviri vanopesana neCGRP: Emgality naAimovig. Mushonga wechina (eptinezumab) unotarisirwa kubvumidzwa munguva pfupi.

Mashandiro avo

Ivo vatatu vanopokana neCGRP izvo zviripo zviripo vanoshanda nenzira dzakasiyana dzakasiyana kubatsira kudzivirira migraine kutemwa nemusoro.

CGRP ipuroteni mumuviri wako. Yakave yakabatana ne vasodilation (kuwedzerwa kwemitsipa yeropa) uye kuzvimba muuropi, izvo zvinogona kukonzeresa kurwadziwa kwemusoro wemusoro. Kukonzera izvi muuropi, CGRP inoda kusunga (kubatanidza) kune ayo anogamuchira. Vanogamuchira mamorekuru pamadziro ehuropi hwako maseru.

Ajovy uye Emgality vanoshanda nekubatanidza kuCGRP. Izvi zvinodzivirira iyo CGRP kubatanidza kune ayo anogamuchira. Aimovig, kune rimwe divi, inoshanda nekubatanidza kune ivo pachavo receptors. Izvi zvinoita kuti CGRP isabatike kwavari.

Nekudzivirira CGRP kubva kunamatira kune yayo inogamuchira, iyi mitatu mishonga inobatsira kudzivirira vasodilation uye kuzvimba. Nekuda kweizvozvo, ivo vanogona kubatsira kudzivirira migraine kutemwa nemusoro.

Pedyo ne pedyo

Iyi chati inofananidza rumwe ruzivo nezve Aimovig, Ajovy, uye Emgality. Iyi mishonga ndiyo mitatu inopesana neCGRP avo vanobvumirwa parizvino kubatsira kudzivirira migraine kutemwa nemusoro. (Kuti udzidze zvakawanda nezvekuti Ajovy anofananidzwa sei nemishonga iyi, ona iyo "Ajovy vs. mimwe mishonga" chikamu pazasi.)

Mitengo inogona kusiyana zvichienderana nenzvimbo yauri, iyo mishonga inoshandiswa, yako inishuwarenzi kufukidza, uye zvirongwa zvekugadzira zvigadzirwa.

Ajovy vs. mimwe mishonga

Unogona kushamisika kuti Ajovy inofananidzwa sei nemimwe mishonga inorayirwa kuti ishandiswe zvakafanana. Pazasi pane enzaniso pakati paAjovy nemimwe mishonga.

Ajovy vs. Aimovig

Ajovy ine mushonga fremanezumab, inova monoclonal antibody. Aimovig ine erenumab, inovawo monoclonal antibody. MaMonoclonal antibodies mishonga yakaitwa kubva kumasero ezvirwere zvemuviri. Vanomisa chiitiko chemamwe mapuroteni mumuviri wako.

Ajovy naAimovig vanoshanda munzira dzakasiyana zvishoma. Nekudaro, ivo vaviri vanomisa chiitiko cheprotein inonzi calcitonin peptide inoenderana negene (CGRP). CGRP inokonzera vasodilation (kuwedzerwa kwemitsipa yeropa) uye kuzvimba muuropi. Izvi zvinogona kukonzera migraine misoro yemusoro.

Nekudzivirira CGRP, Ajovy uye Aimovig kubatsira kudzivirira vasodilation uye kuzvimba. Izvi zvinogona kubatsira kudzivirira migraine kutemwa nemusoro.

Zvishandiso

Ajovy naAimovig vari vaviri FDA-inogamuchirwa kudzivirira migraine kutemwa nemusoro muvakuru.

Mafomu uye manejimendi

Iyo mishonga Ajovy neAimovig zvese zvinouya zviri muchimiro chejekiseni rinopihwa pasi peganda rako (subcutaneous). Unogona kuzvibaya wega mishonga kumba. Ose ari maviri madhiragi anogona kuzvibaya wega munzvimbo nhatu: kumberi kwezvidya zvako, kumashure kwemaoko ako epamusoro, kana dumbu rako.

Ajovy anouya ari muchimiro chesirinji iyo inosanganisirwa neyero imwechete. Ajovy inogona kupihwa seimwe jekiseni ye225 mg kamwe pamwedzi. Seimwe nzira, inogona kupihwa majekiseni matatu e675 mg anoitiswa makota matatu (kamwe chete pamwedzi mitatu).

Aimovig inouya iri muchimiro che autoinjector iyo inosanganisirwa neyero imwechete. Inowanzo kupihwa se 70-mg jekiseni kamwe chete pamwedzi. Asi 140-mg pamwedzi dhizeti inogona kuve iri nani kune vamwe vanhu.

Side migumisiro uye njodzi

Ajovy naAimovig vanoshanda nenzira dzakafanana uye nekudaro vanokonzeresa mamwe emhedzisiro. Izvo zvinokonzeresa mamwe akasiyana mhedzisiro.

Zvimwe zvakajairika mhedzisiro

Aya mazita ane mienzaniso yezvakawanda zvinowanzoitika mhedzisiro inogona kuitika neAjovy, neAimovig, kana nezvose zvinodhaka (kana zvichitorwa zvakasiyana).

• Zvinogona kuitika naAjovy:
  • hapana yakasarudzika yakajairika mhedzisiro
• Zvinogona kuitika naAimovig:
  • kuvimbiswa
  • tsandanyama kana mhasuru
  • Zvirwere zvepamusoro zvekufema senge furuu kana hutachiona hwechivi
  • furu-kunge zviratidzo
  • kurwadziwa shure
• Zvinogona kuitika pamwe naAjovy naAimovig:
  • jekiseni saiti saiti senge kurwadziwa, kunhuwa, kana kutsvuka

Yakakomba mhedzisiro

Iyo yekutanga yakakomba mhedzisiro mhedzisiro kune vese Ajovy uye Aimovig chirwere chakanyanya kusagadzikana. Kuita kwakadai hakuna kujairika, asi zvinogoneka. (Kuti uwane rumwe ruzivo, ona "Allergic reaction" mune "Ajovy mhedzisiro" chikamu pamusoro).

Immune reaction

Mumakiriniki miedzo kune ese ari maviri madhiragi, vashoma muzana yevanhu vakaona immune immune reaction. Izvi zvakakonzera kuti miviri yavo igadzire masoja ekudzivirira kurwisa Ajovy kana Aimovig.

Maantibodies mapuroteni mune immune system anorwisa zvekunze zvinhu mumuviri wako. Mumuviri wako unogona kugadzira ma antibodies kune chero chinhu chekunze. Izvi zvinosanganisira monoclonal antibodies. Kana muviri wako ukagadzira masoja ekudzivirira chirwere kuna Ajovy kana Aimovig, mushonga wacho haugone kukushandira. Asi ramba uchifunga kuti nekuti Ajovy naAimovig vakagamuchirwa muna2018, zvichiri zvekare kuti vazive kuti izvi zvingave zvakajairika sei uye kuti zvingakanganisa sei mashandisiro anoita vanhu mishonga iyi mune ramangwana.

Kubudirira

Iyi mishonga haina kuenzaniswa zvakananga mukuedzwa kwekiriniki. Zvisinei, zvidzidzo zvakawana zvose Ajovy naAimovig kuti vabudirire pakudzivirira zvose episodic uye zvisingaperi migraine misoro.

Uye zvakare, migraine yekurapa nhungamiro inokurudzira chero mushonga senzira yevamwe vanhu. Izvi zvinosanganisira vanhu vasina kukwanisa kudzikisa yavo yemwedzi migraine mazuva akakwana nemimwe mishonga. Ivo zvakare vanosanganisira vanhu vasingakwanise kutsungirira mimwe mishonga nekuda kwemhedzisiro kana kusangana kwemishonga.

Mariro

Mari yeAjovy kana Aimovig inogona kusiyana zvichienderana nehurongwa hwako hwekurapa. Kuenzanisa mitengo yemishonga iyi, tarisa GoodRx.com. Mutengo chaiwo wauchabhadhara kune imwe yemishonga iyi inoenderana nehurongwa hwako hweinishuwarenzi, nzvimbo yauri, uye khemisi yaunoshandisa.

Ajovy vs. Emgality

Ajovy ine fremanezumab, inova monoclonal antibody. Emgality ine galcanezumab, inovawo monoclonal antibody. Monoclonal antibody imhando yemushonga wakagadzirwa kubva kumasero ezvirwere zvemuviri. Inomisa chiitiko chemamwe mapuroteni mumuviri wako.

Ajovy uye Emgality zvese zvinomisa chiitiko checalcitonin peptide inoenderana negene (CGRP). CGRP ipuroteni mumuviri wako. Inokonzera vasodilation (kuwedzera kwemitsipa yeropa) uye kuzvimba muuropi, izvo zvinogona kukonzera maronda emusoro.

Nekumisa CGRP kubva mukushanda, Ajovy uye Emgality zvinobatsira kudzivirira vasodilation uye kuzvimba muuropi. Izvi zvinogona kubatsira kudzivirira migraine kutemwa nemusoro.

Zvishandiso

Ajovy uye Emgality zvese zviri zviviri FDA-inogamuchirwa kudzivirira migraine kutemwa nemusoro muvakuru.

Mafomu uye manejimendi

Ajovy anouya ari muchimiro chesirinji iyo inosanganisirwa neyero imwechete. Emgality inouya muchimiro cheiyo imwe-dhizaini yakatemwa sirinji kana peni.

Ose ari maviri majekiseni akaiswa jekiseni pasi peganda rako (subcutaneous). Iwe unogona kuzvibaya wega Ajovy uye Emgality kumba.

Ajovy inogona kuzvibaya wega uchishandisa imwe yematanho maviri akasiyana. Inogona kupihwa seimwe jekiseni ye225 mg kamwe pamwedzi, kana majekiseni matatu akapatsanurwa (ezere 675 mg) kamwe chete pamwedzi mitatu. Chiremba wako achasarudza yako chaiyo purogiramu iwe.

Emgality inopihwa seimwe jekiseni ye120 mg, kamwe chete pamwedzi. (Mwero wekutanga wemwedzi wekutanga jekiseni maviri anosvika 240 mg.)

Ose Ajovy uye Emgality anogona kuiswa jekiseni munzvimbo nhatu dzinogona kuitika: kumberi kwezvidya zvako, kumashure kwemaoko ako epamusoro, kana dumbu rako. Uye zvakare, Emgality inogona kuiswa jekiseni mumaburi ako.

Side migumisiro uye njodzi

Ajovy uye Emgality zvakafanana zvinodhaka uye zvinokonzeresa zvakajairika uye zvakakomba mhedzisiro.

Zvimwe zvakajairika mhedzisiro

Aya mazita ane mienzaniso yemamwe mhedzisiro mhedzisiro mhedzisiro inogona kuitika neAjovy, neEggality, kana nezvose zviri zviviri zvinodhaka (kana zvichitorwa zvakasiyana).

• Zvinogona kuitika naAjovy:
  • hapana yakasarudzika yakajairika mhedzisiro
• Zvinogona kuitika neEggality:
  • kurwadziwa shure
  • mweya wekufema
  • huro inorwadza
  • sinus chirwere
• Zvinogona kuitika neese Ajovy uye Emgality:
  • jekiseni saiti saiti senge kurwadziwa, kunhuwa, kana kutsvuka

Yakakomba mhedzisiro

Kukanganisa kwakasimba kwehutachiona ndiyo yakakomba mhedzisiro yeAjovy uye Emgality. Hazvisi zvakajairika kuita kwakadai, asi zvinogoneka. (Kuti uwane rumwe ruzivo, ona "Allergic reaction" mune "Ajovy mhedzisiro" chikamu pamusoro).

Immune reaction

Mune akapatsanurwa ekiriniki miedzo yemishonga Ajovy uye Emgality, vashoma muzana yevanhu vakaona immune immune reaction. Aya maitiro ekudzivirira immune akaita kuti miviri yavo igadzire masoja ekudzivirira mishonga.

Maantibodies maprotein immune system anorwisa nyaya dzekunze mumuviri wako. Mumuviri wako unogona kugadzira ma antibodies kune chero chinhu chekunze. Izvi zvinosanganisira monoclonal antibodies senge Ajovy uye Emgality.

Kana muviri wako ukagadzira masoja ekudzivirira muviri kuAjovy kana Emgality, iwo mushonga unogona kusazoshandira iwe.

Zvisinei, zvichiri kukurumidza zvikuru kuziva kuti izvi zvinogona kuitika zvakadii nekuti Ajovy uye Emgality zvakagamuchirwa mu2018. Zvakare zvakare kukurumidza kuziva kuti zvingakanganisa sei mashandisiro anoita vanhu mishonga iyi miviri mune ramangwana.

Kubudirira

Iyi mishonga haina kuenzaniswa zvakananga mukuedzwa kwekiriniki. Nekudaro, zvidzidzo zvakawana zvese Ajovy uye Emgality kuve inoshanda mukudzivirira ese episodic uye chisingaperi migraine misoro.

Uye zvakare, zvese Ajovy uye Emgality zvinokurudzirwa nemazano ekurapa kune vanhu vasingakwanise kutora mimwe mishonga nekuda kwemhedzisiro kana kusangana kwemishonga. Izvo zvinokurudzirwawo kune vanhu vasingakwanise kudzikisa huwandu hwavo hwemwedzi wemigraine kutemwa nemusoro nemimwe mishonga.

Mariro

Mari yeAjovy kana Emgality inogona kusiyana zvichienderana nehurongwa hwako hwekurapa. Kuenzanisa mitengo yemishonga iyi, tarisa GoodRx.com. Mutengo chaiwo wauchabhadhara kune imwe yemishonga iyi inoenderana nehurongwa hwako hweinishuwarenzi, nzvimbo yauri, uye khemisi yaunoshandisa.

Ajovy vs. Botox

Ajovy ine fremanezumab, inova monoclonal antibody. Monoclonal antibody imhando yemushonga wakagadzirwa kubva kumasero ezvirwere zvemuviri. Ajovy inobatsira kudzivirira migraine kutemwa nemusoro nekumisa chiitiko chemamwe mapuroteni anomutsa migraines.

Chinhu chikuru chemushonga muBotox ndeye onabotulinumtoxinA. Uyu mushonga chikamu chekirasi yemishonga inozivikanwa semaurotoxin. Botox inoshanda nekuomesa mhasuru kwechinguva mukati mayo jekiseni. Izvi zvinoitika pamhasuru zvinochengetedza zviratidzo zvekurwadziwa kubva pakuchinjwa. Zvinofungidzirwa kuti chiito ichi chinobatsira kudzivirira migraine kutemwa nemusoro vasati vatanga.

Zvishandiso

Iyo FDA yakabvumidza Ajovy yekudzivirira isingagumi kana episodic migraine musoro misoro muvakuru.

Botox yakagamuchirwa kudzivirira isingagumi migraine kutemwa nemusoro muvanhu vakuru. Botox yakave yakabvumidzwa kurapa akawanda mamiriro, anosanganisira:

• mhasuru kusimba
• yakanyanyisa kuita dundira
• vangadikitira zvakanyanya
• remuromo dystonia (inorwadza mutsipa mutsipa)
• eyelid spasms

Mafomu uye manejimendi

Ajovy inouya seyakagadzirirwa imwe-dhi sirinji. Inopihwa sejekiseni pasi peganda rako (subcutaneous) raunogona kuzvipa uri kumba, kana kuti mupi wehutano anokupa kuhofisi yechiremba wako.

Ajovy inogona kupihwa pane imwe yematanho maviri akasiyana: imwe 225-mg jekiseni kamwe pamwedzi, kana majekiseni matatu akapatsanurwa (akazara e675 mg) kamwe chete pamwedzi mitatu. Chiremba wako achasarudza yako chaiyo purogiramu iwe.

Ajovy inogona kujowa munzvimbo nhatu dzinogona kuitika: kumberi kwezvidya zvako, kumashure kwemaoko ako epamusoro, kana dumbu rako.

Botox inopihwawo sejekiseni, asi inogara ichipiwa muhofisi yechiremba. Inopinzwa mumhasuru (intramuscular), kazhinji pamasvondo gumi nemaviri.

Saiti idzo Botox inowanzojowa inosanganisira pahuma yako, kumusoro uye padyo nenzeve dzako, padhuze nemusoro wako webvudzi pazasi pemutsipa wako, uye kumashure kwemutsipa wako nemapfudzi. Pakushanya kwega kwega, chiremba wako anowanzo kukupa majekiseni makumi matatu nematatu munzvimbo idzi.

Side migumisiro uye njodzi

Ajovy neBotox zvese zvinoshandiswa kudzivirira migraine kutemwa nemusoro, asi zvinoshanda nenzira dzakasiyana mumuviri. Naizvozvo, vane mamwe akafanana mhedzisiro, uye mamwe akasiyana.

Zvimwe zvakajairika mhedzisiro

Aya mazita ane mienzaniso yemigumisiro yakakomba inogona kuitika neAjovy, neBotox, kana nemishonga miviri (kana inotorwa zvakasiyana).

• Zvinogona kuitika naAjovy:
  • mashoma mashoma akasarudzika mhedzisiro
• Inogona kuitika neBotox:
  • furu-kunge zviratidzo
  • musoro kana kuwedzera migraine musoro
  • eyelid ikadonha
  • kumeso mhasuru kuoma mitezo
  • kurwadziwa kwemutsipa
  • kuomarara kwemhasuru
  • kurwadziwa kwemhasuru uye kushaya simba
• Zvinogona kuitika neese Ajovy neBotox:
  • jekiseni saiti maitiro

Yakakomba mhedzisiro

Aya mazita ane mienzaniso yemhedzisiro mhedzisiro mhedzisiro inogona kuitika neAjovy, iine Xultophy, kana nezvose zviri zviviri zvinodhaka (kana zvichitorwa zvakasiyana).

• Zvinogona kuitika naAjovy:
  • mashoma akasarudzika akakomba mhedzisiro
• Inogona kuitika neBotox:
  • kupararira kwekuoma mitezo kune mhasuru dziri padyo *
  • kunetseka kumedza uye kufema
  • hutachiona hwakakomba
• Zvinogona kuitika neese Ajovy neBotox:
  • zvakakomba zvemuviri kukanganiswa

Botox ine yambiro yebhokisi kubva kuDAA yekupararira kwekuoma mitezo kusvika kumhasuru dziri pedyo zvichitevera jekiseni. Nyevero yebhokisi ndiyo yambiro yakasimba iyo FDA inoda. Inozivisa vanachiremba nevarwere nezvezvinodhaka zvinogona kuva nenjodzi.

Kubudirira

Chisingaperi migraine misoro yemusoro ndiyo chete mamiriro ayo ari maviri Ajovy neBotox anoshandiswa kudzivirira.

Mirayiridzo yekurapa inokurudzira Ajovy senzira inogoneka kune vanhu vasingakwanise kudzikisa huwandu hwavo hwemusoro wemigraine zvakakwana nemimwe mishonga. Ajovy inokurudzirwawo kune vanhu vasingakwanise kutsungirira mimwe mishonga nekuda kwemhedzisiro yavo kana kudyidzana kwemishonga.

IAmerican Academy yeNeurology inokurudzira Botox senzira yekurapa kune vanhu vane chirwere chisingaperi chemigraine.

Zvidzidzo zvekuchipatara hazvina kuenzanisa zvakananga kushanda kwaAjovy neBotox. Asi zvidzidzo zvakasiyana zvakaratidza zvose Ajovy neBotox kuti zvive zvinobudirira mukudzivirira kusingaperi kwemigraine misoro.

Mariro

Mari yeAjovy kana Botox inogona kusiyana zvichienderana nehurongwa hwako hwekurapa. Kuenzanisa mitengo yemishonga iyi, tarisa GoodRx.com. Mutengo chaiwo wauchabhadhara kune imwe yemishonga iyi inoenderana nehurongwa hwako hweinishuwarenzi, nzvimbo yauri, uye khemisi yaunoshandisa.

Ajovy mutengo

Sezvo nemishonga yese, mitengo yeAjovy inogona kusiyana.

Yako chaiyo mutengo inoenderana neinishuwarenzi yako yekuvhara, nzvimbo yako, uye pharmacy yaunoshandisa.

Rubatsiro rwemari

Kana iwe uchida rutsigiro rwemari kubhadhara Ajovy, rubatsiro rwuripo.

Teva Pharmaceuticals, iyo inogadzira Ajovy, ine mari yekuchengetedza iyo inogona kukubatsira iwe kubhadhara zvishoma kune Ajovy. Kuti uwane rumwe ruzivo uye kuti uone kana iwe uchikodzera, shanyira iyo webhusaiti webhusaiti.

Ajovy chipimo chemushonga

Ruzivo runotevera runotsanangura zvakajairwa madosi eAjovy. Zvisinei, iva nechokwadi chekutora muyero uyo chiremba wako anokuraira iwe. Chiremba wako achaona yakanakisa dosing purogiramu yako.

Mafomu emishonga uye simba

Ajovy anouya mune imwechete-dhizaini yakasarudzwa sirinji. Sirinji yega yega ine 225 mg ye fremanezumab mu 1.5 mL yemhinduro.

Ajovy inopihwa sejekiseni pasi peganda rako (subcutaneous). Unogona kuzvibaya-baya mushonga kumba, kana mupi wezvehutano anogona kukupa jekiseni kuhofisi yechiremba wako.

Dosage for migraine headache kudzivirira

Pane maviri akakurudzirwa madhisiki mashejuru:

• imwe 225-mg jekiseni subcutaneous inopihwa mwedzi wega wega, kana
• matatu 225-mg subcutaneous majekiseni anopiwa pamwechete (imwe mushure meimwe) kamwe chete pamwedzi mitatu

Iwe nachiremba wako muchaona yakanakisa dosing purogiramu yako, zvichibva pane zvaunofarira uye mararamiro.

Ko kana ndikapotsa dosi?

Kana iwe ukakanganwa kana kupotsa dosi, tora iyo dosi nekukurumidza iwe pauchayeuka.Mushure meizvozvo, tangazve yakajairwa chirongwa chakakurudzirwa.

Semuenzaniso, kana iwe uri pane yemwedzi purogiramu, ronga iyo inotevera dhivhai kwemavhiki mana mushure mekuita kwako dhizaini. Kana iwe uri pane yekota purogiramu, tungamira inotevera dhivhisi gumi nemaviri masvondo mushure mekuita kwako dhizaini.

Ndichada here kushandisa mushonga uyu kwenguva refu?

Kana iwe nachiremba wako mukaona kuti Ajovy yakachengeteka uye inoshanda kwauri, unogona kushandisa mushonga kwenguva refu kudzivirira migraine kutemwa nemusoro.

Maitiro ekutora Ajovy

Ajovy jekiseni rinopihwa pasi peganda (subcutaneous) kamwe chete pamwedzi kana kamwe chete pamwedzi mitatu. Iwe unogona kana kubaya jekiseni pachako kumba, kana kuve nemupi wezvehutano anokupa majekiseni kuhofisi yechiremba wako. Kekutanga iwe paunowana mushonga weAjovy, wako wekuchengeta hutano anogona kutsanangura maitiro ekubaya mushonga iwe pachako.

Ajovy inouya seyadhi-imwe, 225-mg sirinji yakasarudzika. Sirinji imwe neimwe ine dosi imwe chete uye inofanirwa kushandiswa kamwe chete ikazoraswa.

Pazasi pane ruzivo rwekuti ungashandise sei syringe yakasarudzika. Kune rumwe ruzivo, vhidhiyo, uye mifananidzo yemirayiridzo yejekiseni, ona webhusaiti yemugadziri.

Jekiseni

Chiremba wako achapa 225 mg kamwe pamwedzi, kana 675 mg kamwe pamwedzi mitatu (makota matatu). Kana iwe wakatemerwa 225 mg pamwedzi, iwe uchazvipa iwe jekiseni rimwe. Kana iwe wakatemerwa 675 mg makota matatu, iwe unozozvipa iwe matatu akasiyana majekiseni imwe mushure meimwe.

Kugadzirira kubaya jekiseni

• Maminitsi makumi matatu usati wabaya mushonga, bvisa sirinji kubva mufiriji. Izvi zvinobvumidza mushonga kuti udziye uye uuye kune tembiricha yemukati. Chengeta chivharo pane sirinji kusvikira wagadzirira kushandisa sirinji. (Ajovy inogona kuchengetwa mukamuri tembiricha kwemaawa anosvika makumi maviri nemana. Kana Ajovy ikachengetwa kunze kwefriji kwemaawa makumi maviri nemana isingashandiswi, usayiise zvakare mufiriji. Irase mumudziyo wako unopinza.)
• Usaedze kudziya iyo sirinji nekukasira nekuisa microwave iyo kana kumhanyisa mvura inopisa pamusoro payo. Zvakare, usazununguse sirinji. Kuita zvinhu izvi kunogona kuita Ajovy kushomeka uye kushanda.
• Paunotora sirinji kubva mupakeji yayo, ita shuwa kuti uidzivirire kubva pachiedza.
• Paunenge uchimirira sirinji kudziya kusvika kukamuri yemukati, tora gauze kana donje bhora, chipukuta doro, uye mudziyo wako wekurasa marara. Zvakare, ita shuwa kuti iwe unayo chaiyo nhamba yejekiseni reyako yakatemwa dosi.
• Tarisa sirinji kuti uone kuti mushonga hauna makore kana kupera. Mvura yacho inofanira kunge yakajeka kune zvishoma yero. Zvakanaka kana paine mapundu. Asi kana iyo mvura yakasviba kana kuti makore, kana kana paine zvidimbu zvidiki zvakaoma mukati mayo, usashandise. Uye kana paine chero kupaza kana kuvuza musyinji, usashandise. Kana zvichidikanwa, bata chiremba wako nezve kuwana nyowani.
• Shandisa sipo nemvura kugeza maoko, uye wosarudza nzvimbo yejekiseni rako. Unogona kubaya pasi peganda rako munzvimbo nhatu idzi:
• kumberi kwehudyu dzako (angangoita maviri masendimita pamusoro pebvi rako kana maviri masendimita pazasi peguyo rako)
• kumashure kwemaoko ako ekumusoro
• dumbu rako (angangoita mainji maviri kubva padumbu rako)
• Kana iwe uchida kubaya mushonga musana weruoko rwako, mumwe munhu angangoda kubaya iwe mushonga iwe.
• Shandisa yekupukuta doro kunatsa jekiseni nzvimbo yawasarudza. Ive neshuwa kuti doro rakanyatso kuoma usati wajova mushonga.
• Kana iwe uchizvipa iwe majekiseni matatu, usazvipe iwe chero majekiseni munzvimbo imwechete. Uye usambo jekesa munzvimbo dzakakuvara, dzvuku, dzine mavanga, dzakatemwa nyora, kana dzakaoma kubata.

Kubaya jekiseni Ajovy yakatemwa sirinji

1. Bvisa chivharo chetsono pajekiseni urikande mumarara.
2. Nyoronyoronyora kanokwana ka inchi imwe yeganda iwe yaunoda kubaya.
3. Isa tsono mukati meganda rakapetwa pakona yemadhigirii makumi mashanu kusvika makumi mapfumbamwe.
4. Kana tsono yaiswa chete, shandisa chigunwe chako kuti usudurure zvishoma nezvishoma iyo plunger kusvika kwazvichaenda.
5. Mushure mekubaya Ajovy, dhonza tsono yakanangana neganda uye usunungure danga reganda. Kuti urege kunamatira pachako, usadzorere tsono.
6. Nyoronyoronyoro bhora rekotoni kana gauze panzvimbo yejekiseni kwemasekondi mashoma. Usazora nzvimbo.
7. Kanda syringe yakashandiswa uye tsono mumudziyo wako wekurasa pakarepo.

Nguva

Ajovy inofanirwa kutorwa kamwe chete pamwedzi kana kamwe chete pamwedzi mitatu (makota matatu), zvinoenderana nezvinorairwa nachiremba wako. Inogona kutorwa chero nguva yezuva.

Kana iwe ukarasikirwa neiyo dose, tora Ajovy nekukurumidza sekurangarira kwako. Iyo inotevera dosi inofanirwa kuve mwedzi mumwe kana mwedzi mitatu mushure mekutora iyo, zvichienderana neyako yakakurudzirwa dosing purogiramu. Chiyeuchidzo chemushonga chingakubatsira kuyeuka kutora Ajovy panguva.

Kutora Ajovy nechikafu

Ajovy inogona kutorwa pamwe kana pasina chikafu.

Anoshanda sei Ajovy

Ajovy inorwisa munhu monoclonal. Rudzi rwemushonga iyi yakakosha immune immune protein inogadzirwa murabhoritari. Ajovy anoshanda nekumisa chiitiko cheprotein inonzi calcitonin gene-inoenderana peptide (CGRP). CGRP inobatanidzwa mukudzora (kuwedzera kwemidziyo yeropa) uye kuzvimba muuropi hwako.

CGRP inofungidzirwa kuti inoita basa rakakosha mukukonzera migraine kutemwa nemusoro. Muchokwadi, apo vanhu pavanotanga kuwana musoro wemigraine, vane huwandu hwakakwira hweCGRP muropa ravo. Ajovy inobatsira kuchengetedza migraine misoro kubva kutanga nekumisa chiitiko cheCGRP.

Mazhinji mishonga inonanga (ita pa) akawanda makemikari kana zvikamu zvemasero mumuviri wako. Asi Ajovy uye mamwe ma monoclonal antibodies anongonongedza chinhu chimwe chete mumuviri. Nekuda kweizvozvo, panogona kuve nekushomeka kwekudyidzana kwemishonga uye mhedzisiro neAjovy. Izvi zvinogona kuzviita sarudzo yakanaka kune vanhu vasingakwanise kutora mimwe mishonga nekuda kwemhedzisiro kana kusangana kwemishonga.

Ajovy inogona zvakare kuve sarudzo yakanaka kune vanhu vakaedza mimwe mishonga, asi mishonga haina kuita zvakakwana kudzikisa huwandu hwemazuva emigraine.

Zvinotora nguva yakareba sei kuti zvishande?

Zvinogona kutora mavhiki mashoma kuti chero migraine ichinje iyo Ajovy inokonzeresa kuti ionekwe. Uye zvinogona kutora mwedzi yakati wandei kuti Ajovy inyatso shanda.

Mhedzisiro yezvidzidzo zvekuchipatara yakaratidza kuti vanhu vazhinji vakatora Ajovy vakasangana nemazuva mashoma emigraine mukati memwedzi mumwe wekutora yavo yekutanga dhosi. Kwemwedzi yakati wandei, kuwanda kwemazuva emigraine kwakaramba kuchiderera kune vanhu vari muchidzidzo.

Ajovy nedoro

Iko hakuna kudyidzana pakati peAjovy nedoro.

Nekudaro, kune vamwe vanhu, kunwa doro vachitora Ajovy zvinoita sekunge kunoita kuti mushonga usanyanya kushanda. Izvi zvinodaro nekuti doro chinhu chinokonzeresa kuvanhu vazhinji, uye kunyangwe diki doro rinogona kukonzeresa kutemwa nemusoro kwavari.

Kana iwe ukaona kuti doro rinokonzera mamwe marwadzo kana kuwanda kwemigraine kutemwa nemusoro, unofanirwa kudzivirira zvinwiwa zvine doro.

Ajovy kudyidzana

Ajovy haasati aratidzwa kuti anofambidzana nemimwe mishonga. Zvisinei, zvichiri kukosha kuti utaure nachiremba wako kana wemishonga nezve chero mishonga inonyorwa, mavitamini, zvinowedzerwa, uye mishonga yekutenga yaunotora usati watanga Ajovy.

Ajovy uye nhumbu

Hazvizivikanwe kana Ajovy yakachengeteka kushandisa panguva yekuzvitakura. Pakapihwa Ajovy kuvakadzi vane nhumbu muzvidzidzo zvemhuka, hapana njodzi yakaratidzwa kune nhumbu. Asi mhedzisiro yezvidzidzo zvemhuka haigare ichifungidzira kuti mushonga ungakanganisa sei vanhu.

Kana iwe uine pamuviri kana kufunga nezvekuva nepamuviri, taura nachiremba wako. Ivo vanogona kubatsira kuona kana Ajovy isarudzo yakanaka kwauri. Ungangoda kumirira kuti ushandise Ajovy kudzamara usisiri nemimba.

Ajovy uye kuyamwisa

Hazvizivikanwe kana Ajovy achipfuura mumukaka wemunhu wemukaka. Naizvozvo, hazvina kujeka kana Ajovy yakachengeteka kushandisa panguva yekuyamwisa.

Kana iwe uri kufunga nezve kuita Ajovy kurapwa iwe paunenge uchiyamwa, taura nachiremba wako nezve izvo zvinogona kubatsira uye njodzi. Kana iwe ukatanga kutora Ajovy, ungatofanira kurega kuyamwisa.

Mibvunzo yakajairika nezve Ajovy

Heano mhinduro kumimwe mibvunzo inowanzo bvunzwa nezve Ajovy.

Anogona here Ajovy kurapa migraine musoro?

Kwete, Ajovy haisi kurapwa kwemusoro wemusoro. Ajovy inobatsira kudzivirira migraine kutemwa nemusoro vasati vatanga.

Ajovy akasiyana papi nemimwe migraine zvinodhaka?

Ajovy anosiyana nemamwe akawanda migraine madhiragi nekuti ndiwo mumwe wemishonga yekutanga yakagadzirwa kubatsira kudzivirira migraine kutemwa nemusoro. Ajovy chikamu chekirasi nyowani yemishonga inonzi calcitonin gene-related peptide (CGRP) vanopikisa.

Yakawanda mimwe mishonga inoshandiswa kudzivirira migraine kutemwa nemusoro kwakagadzirwa nekuda kwakasiyana siyana, sekurapa pfari, kushushikana, kana kuwedzerwa kweropa. Mazhinji emishonga iyi anoshandiswa kure-chitaridzi kubatsira kudzivirira migraine kutemwa nemusoro.

Ajovy inosiyanawo nemimwe yakawanda mishonga yemigraine mukuti inojowa kamwe chete pamwedzi kana kamwe chete pamwedzi mitatu. Mimwe mimwe mishonga inoshandiswa kudzivirira migraine misoro inouya semapiritsi aunofanira kutora kamwe chete pazuva.

Imwe nzira yekushandisa zvinodhaka ndeyeBotox. Botox zvakare jekiseni, asi iwe unorigamuchira kamwe chete pamwedzi mitatu muhofisi yechiremba wako. Unogona kuzvibaya wega Ajovy kumba kana kuva nemupi wezvehutano anokupa jekiseni kuhofisi yechiremba wako.

Zvakare, Ajovy inorwisa munhu monoclonal, inova mhando yemushonga wakagadzirwa kubva kumasero ezvirwere zvemuviri. Chiropa hachiputsi mishonga iyi, sezvazvinoita nemimwe mishonga yakawanda inoshandiswa kudzivirira migraine kutemwa nemusoro. Izvi zvinoreva kuti Ajovy uye mamwe monoclonal antibodies ane mashoma mashandisirwo emishonga kupfuura mimwe mishonga inobatsira kudzivirira migraine kutemwa nemusoro.

Ko Ajovy anorapa migraine musoro here?

Kwete, Ajovy haibatsire kupora migraine kutemwa nemusoro. Parizvino, hapana mishonga inowanika inogona kurapa migraine kutemwa nemusoro. Iyo migraine zvinodhaka zvinowanikwa zvinogona kubatsira kudzivirira kana kurapa migraine misoro.

Kana ndikatora Ajovy, ndinogona here kurega kutora yangu mimwe mishonga yekudzivirira?

Izvo zvinoenderana. Mhinduro yemunhu wese kuna Ajovy yakasiyana. Kana mushonga uyu ukaderedza huwandu hwemusoro wako wemigraine pasi kusvika pauwandu hunogoneka, zvinokwanisika kuti iwe ugone kuzomira kushandisa mimwe mishonga yekudzivirira. Asi kana iwe ukatanga kutora Ajovy, chiremba wako anozozvipa pamwe chete nemimwe mishonga yekudzivirira.

Chidzidzo chekiriniki chakawana kuti Ajovy yakachengeteka uye inoshanda kuti ishandiswe nemimwe mishonga yekudzivirira. Mimwe mishonga inogona kupihwa nachiremba wako naAjovy inosanganisira topiramate (Topamax), propranolol (Inderal), uye mamwe mishonga yekudzvinyirira. Ajovy inogona zvakare kushandiswa neonabotulinumtoxinA (Botox).

Mushure mekuyedza Ajovy kwemwedzi miviri kana mitatu, chiremba wako angangotaura newe kuti aone kuti mushonga unoshanda sei kwauri. Panguva iyoyo, imi vaviri mungasarudza kuti munofanira kurega kutora mimwe mishonga yekudzivirira, kana kuti munofanira kudzikisira muyero weiyo madhiragi.

Ajovy kudarika

Kubaya majekiseni akawanda eAjovy kunogona kuwedzera njodzi yekujowa saiti saiti. Kana iwe uri weergoria kana hypersensitive kuna Ajovy, iwe unogona kuve uri panjodzi yekuita zvakakomba zvakanyanya.

Ovhadhozi zviratidzo

Zviratidzo zvekuwedzeredza zvinogona kusanganisira:

• kurwadziwa kwakanyanya, kuchenesa, kana kutsvuka munzvimbo iri padyo nejekiseni
• kufashaira
• mikoko
• angioedema (kuzvimba pasi peganda)
• kuzvimba kwerurimi, huro, kana muromo
• kunetseka kufema

Zvekuita kana ovhadhozi

Kana iwe uchifunga kuti watora zvakawandisa zvemushonga uyu, fonera chiremba wako kana kutsvaga nhungamiro kubva kuAmerican Association of Poison Control Centers pa800-222-1222 kana kuburikidza nechavo online chishandiso Asi kana zviratidzo zvako zvakakomba, fonera 911 kana kuenda kukamuri yepedyo yevanokurumidza ipapo.

Ajovy yambiro

Usati watora Ajovy, taura nachiremba wako nezve nhoroondo yako yehutano. Iwe haufanire kutora Ajovy kana iwe uine nhoroondo yeakakomba hypersensitivity maitiro kune Ajovy kana chero ayo maisanganiswa. Iyo yakakomba hypersensitivity reaction inogona kukonzera zviratidzo senge:

• kuputika kweganda
• kuvava
• kunetseka kufema
• angioedema (kuzvimba pasi peganda)
• kuzvimba kwerurimi, muromo, nehuro

Ajovy kupera

Kana Ajovy atengeswa kubva kupharmasi, wemishonga anowedzera zuva rekupera kune zvakanyorwa pamudziyo. Zuva iri rinowanzo kuve gore rimwe kubva musi wakapihwa mushonga.

Chinangwa chemazuva ekupera akadaro ndechekuvimbisa kushanda kwemushonga panguva ino. Chimiro chazvino cheKudya neDrug Administration (FDA) ndechekudzivirira kushandisa akapera mishonga.

Inguva yakareba sei mushonga unoramba wakanaka unogona kubva pane zvakawanda zvinhu, zvinosanganisira kuti uye kupi mushonga unochengeterwa.

Ajovy majekiseni anofanirwa kuchengetwa mufiriji iri mumudziyo wepakutanga kuvadzivirira kubva pachiedza. Inogona kuchengetedzwa zvakachengeteka mufiriji kwemwedzi inosvika makumi maviri nemana, kana kusvika zuva rekupera rakanyorwa pane mudziyo. Paunongobviswa mufiriji, sirinji imwe neimwe inofanira kushandiswa mukati memaawa makumi maviri nemana.

Kana iwe usina kushandisa mishonga yakapfuura nguva yekupera, taura nachiremba wako nezvekuti ungangokwanisa kuishandisa.

Disiki:Nhau Dzokurapa Nhasi yakaedza zvese kuti ive nechokwadi chekuti ruzivo rwese nderwechokwadi, rwakakwana, uye rwechizvino-zvino. Nekudaro, chinyorwa ichi hachifanirwe kushandiswa sekutsiva ruzivo uye hunyanzvi hweane rezinesi rezvehutano. Iwe unofanirwa kugara uchibvunza chiremba wako kana imwe nyanzvi yehutano usati watora chero mushonga. Ruzivo rwezvinodhaka ruri pano runogona kuchinja uye haruna kuitirwa kufukidza ese mashandisirwo, madhairekitori, chenjedzo, kunyeverwa, kudyidzana kwezvinodhaka, allergic reaction, kana mhedzisiro. Kushaikwa kweyambiro kana rumwe ruzivo rwemushonga wakapihwa hakuratidze kuti mushonga kana musanganiswa wezvinodhaka wakachengeteka, unoshanda, kana wakakodzera kuvarwere vese kana kushandiswa kwese chaiko.