Antimitochondrial Antibody Bvunzo (AMA)

Zvemukati

• Nei AMA bvunzo yakarairwa?
• Ko iyo AMA bvunzo inoitiswa sei?
• Ndeipi njodzi dzeyedzo ye AMA?
• Kunzwisisa yako AMA bvunzo mhedzisiro

Chii chinonzi antimitochondrial antibody bvunzo?

Iyo mitochondria inogadzira simba rekuti maseru ari mumuviri wako ashandise. Ivo akakosha kune zvakajairika mashandiro emaseru ese.

Antimitochondrial antibodies (AMAs) muenzaniso wemhinduro yekuzvimiririra inoitika kana muviri uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiita. Kana izvi zvikaitika, immune system inorwisa muviri sekunge ihwo hutachiona.

Iyo AMA bvunzo inoratidza yakakwira mizinga yeaya maantibhakitiriya muropa rako. Iyo bvunzo inowanzo shandiswa kuona autoimmune mamiriro inozivikanwa seyakanyanya biliary cholangitis (PBC), yaimbozivikanwa seyekutanga biliary cirrhosis.

Nei AMA bvunzo yakarairwa?

PBC inokonzerwa ne immune immune kurwisa kune madiki bile ducts mukati mechiropa. Dzakakuvadzwa bile ducts dzinokonzeresa kukuvara, izvo zvinogona kutungamira mukundikana kwechiropa. Aya mamiriro anounzawo njodzi yakawedzera yekenza yechiropa.

Zviratidzo zvePBC zvinosanganisira:

• kuneta
• ganda rinonhuwa
• yero yeganda, kana jaundice
• kurwadziwa mudumbu repamusoro kurudyi
• kuzvimba, kana edema yemaoko nemakumbo
• kuwanda kwemvura mudumbu
• muromo wakaoma uye maziso
• kuonda

Chiyero che AMA chinoshandiswa kubatsira kusimbisa kurapwa kwechiremba kwePBC. Chiyero chisina kujairika che AMA choga hachina kukwana kuti uongorore kusagadzikana. Kana izvi zvikaitika, chiremba wako anogona kuraira kumwe kuyedzwa, kusanganisira zvinotevera:

Anti-nyukiliya antibodies (ANA): Vamwe varwere vane PBC vanoongororawo zvakanaka kune aya ma antibodies.

Transaminase: Iyo enzymes alanine transaminase uye aspartate transaminase yakanangana nechiropa. Kuedzwa kunozivisa huwandu hwakawandisa, hunowanzo kuve chiratidzo chechirwere chechiropa.

Bilirubin: Ichi chinhu chinogadzirwa nemuviri kana masero matsvuku eropa achiputsika. Inoburitswa kuburikidza neweti uye chigaro. Mari yakawanda inogona kuratidza chirwere chechiropa.

Albumin: Iyi ipuroteni inogadzirwa muchiropa. Zvikamu zvakaderera zvinogona kuratidza kukuvara kwechiropa kana chirwere.

C-inoshanda mapuroteni: Uyu muedzo unowanzo kurairwa kuti uongorore lupus kana chirwere chemoyo, asi icho chinogona zvakare kuve chiratidzo cheimwe autoimmune mamiriro.

Anti-inotsvedzerera tsandanyama antibodies (ASMA): Uyu muedzo unowanzo kupihwa pamwe chete neANA bvunzo uye unobatsira pakuongorora autoimmune hepatitis.

AMA kuyedza kunogona zvakare kushandiswa kukutarisa iwe kune PBC kana kuongororwa kweropa kwakajairwa kuchiratidza kuti iwe une mazinga epamusoro ealkaline phosphatase (ALP) kupfuura zvakajairwa. Iyo yakakwira ALP nhanho inogona kuve chiratidzo cheiyo bile duct kana chirwere chenduru.

Ko iyo AMA bvunzo inoitiswa sei?

Iko AMA bvunzo kuongorora ropa. Mukoti kana nyanzvi inokweva ropa rako kubva mutsinga iri pedyo negokora kana ruoko. Ropa iri richaunganidzwa muhubhu roendeswa kunzvimbo yekuongorora.

Chiremba wako achakubata kuti atsanangure zvawanikwa kana zvave kuwanikwa.

Ndeipi njodzi dzeyedzo ye AMA?

Iwe unogona kusangana nekusagadzikana kana iyo yeropa sampuro yakadhonzwa. Panogona kuve nekurwadziwa panzvimbo yekubaya panguva kana mushure mekuedzwa. Muzhinji, njodzi dzekukweva ropa dzakaderera.

Zvimwe zvinogona kuisa njodzi zvinosanganisira:

• kunetsekana kuwana sampuro, zvichikonzera tsvimbo dzakawanda dzetsono
• kubuda ropa zvakanyanya panzvimbo yesero
• kufenda nekuda kwekurasikirwa neropa
• kuunganidzwa kweropa pasi peganda, rinozivikanwa sehematoma
• hutachiona panzvimbo yekubaya

Hapana gadziriro inodikanwa bvunzo iyi.

Kunzwisisa yako AMA bvunzo mhedzisiro

Zvakajairwa bvunzo mhedzisiro hazvina kunaka kune AMA. AMA yakanaka inoreva kuti pane mwero inoonekwa yemasoja eropa. Kunyangwe iyo yakanaka AMA bvunzo inowanzo kuve yakabatana nePBC, inogona zvakare kuve yakanaka mune autoimmune hepatitis, lupus, rheumatoid arthritis, uye graft-versus-host chirwere. Aya ma antibodies anongova chikamu chimwe chega autoimmune nyika iri kugadzirwa nemuviri.

Kana iwe uine mhedzisiro yakanaka, iwe ungangodaro unoda kuwedzerwa kuyedzwa kuti usimbise kuongororwa kwako. Kunyanya, chiremba wako anogona kuraira chiropa biopsy kutora sampuro kubva muchiropa. Chiremba wako anogona zvakare kuraira CT kana MRI yechiropa chako.