Heano maDhiri neKupa Convalescent Plasma yeCOVID-19 Varwere

Zvemukati

• Saka, Chii chinonzi Convalescent Plasma Therapy, Chaizvo?
• Ndiani Anogona Kupa Convalescent Plasma yeCOVID-19?
• Chii Chinogadziriswa Plasma Mupiro?
• Ongororo ye

Kubva mukupera kwaKurume, chirwere checoronavirus chakaramba chichidzidzisa nyika - nepasirese - izwi rese reizwi nyowani: kuremara munharaunda, midziyo yekuzvidzivirira (PPE), kutsvaga kwekubata, kungo taura mashoma. Zvinoita sekunge zuva rega rega rekufamba kwedenda (rinoratidzika serisingaperi) pane chiitiko chitsva chinopa iyo chaiyo posse yemitsara yekuwedzera kune iri kuramba ichikura COVID-19 duramazwi. Imwe yeazvino ekuwedzera kuwedzerwa kune yako inowedzera kupfuma vocab? Convalescent plasma therapy.

Hazvizivikanwe? ndichatsanangura...

Musi waAugust 23, 2020 iyo US Chikafu neDrug Administration (FDA) yakabvumidza kushandiswa kwechimbichimbi kweplasma convalescent - chikamu cheropa-chakapfuma cheropa chakatorwa kubva kune vakadzoserwa varwere veCOVID-19 - pakurapa kwenyaya dzakakomba dzekoronavirus. Zvino, pasingasviki vhiki rimwe gare gare, musi waGunyana 1, iyo COVID-19 Treatment Guidelines Panel, chikamu cheNational Institutes of Health (NIH), yakabatana nehurukuro, ichiti pane "data isina kukwana yekukurudzira kungave kana kupokana nekushandiswa yeplasma inogonha yekurapa COVID-19. ”

Pamberi pemutambo uyu, convalescent plasma yakapihwa varwere veCCIDID-19 vanorwara kuburikidza neMayo Clinic-inotungamirwa Yakawedzera Kupinda Chirongwa (EAP), iyo yaida kunyoreswa kwachiremba kuitira kukumbira plasma yevarwere, sekureva kweFDA. Ikozvino, kuenda kumberi, EAP yapera uye iri kutsiviwa neFDA's Emergency Use Authorization (EUA), iyo inobvumira vanachiremba nezvipatara kukumbira plasma pasina kusangana neimwe nzira yekunyoresa. Asi, sekusimbiswa neshoko razvino reNIH, kumwe kutsvagurudza kunodiwa chero munhu asati agona zviri pamutemo (uye zvakachengeteka) kukurudzira convalescent plasma kurapwa sekurapa kwekuvimbika kweCOVID-19.

Convalescent plasma therapy inowanikwa zvakanyanya kupfuura nakare kose senge ingangoita kurapwa kweCCIDID-19 muUS, asi chii chaizvo? Uye ungapa sei convalescent plasma yevarwere veCOVID-19? Mberi, zvese zvaunoda kuti uzive.

Saka, Chii chinonzi Convalescent Plasma Therapy, Chaizvo?

Kutanga, chii chinonzi convalescent plasma? Convalescent (chirevo uye zita) zvinoreva chero munhu ari kupora kubva kuchirwere, uye plasma ndiyo yero, yemvura chikamu cheropa chine masoja ekudzivirira chirwere, maererano neFDA. Uye, kana ukarasikirwa ne7th-grade biology kirasi, antibodies ndiwo mapuroteni akaumbwa kuti arwisane nehumwe hutachiona mushure mekuve nehutachiona.

Nekudaro, convalescent plasma ingoriwo plasma kubva kune mumwe munhu akapora kubva muchirwere - mune iyi nyaya, COVID-19, anodaro Brenda Grossman, MD, director wezvekurapa weTransfusion Medicine paBarnes-Jewish Hospital, uye purofesa kuWashington University Chikoro che Mushonga muSt. "Plasmas dzeConvalescent dzakashandiswa munguva yakapfuura, nematanho akasiyana ekushanda, kune dzakawanda zvirwere zvinotapukira, kusanganisira Spanish Flu, SARS, MERS, uye Ebola," anodaro Dr. Grossman.

Zvino, pano ndipo panouya "kurapa": Kana plasma yangowanikwa kubva kumunhu akapora, inoisirwa mumurwere aripo (uye kazhinji zvakanyanya) anorwara kuitira kuti masoja ekudzivirira chirwere agone "kubvisa hutachiona uye kuwedzera kujekeswa kwehutachiona. kubva mumuviri, ”anodaro Emily Stoneman, MD, nyanzvi yezvirwere zvinotapukira paUniversity yeMichigan muAnn Arbor. Mune mamwe mazwi, rinoshandiswa "kusimudzira hutachiona hwemurwere uye netariro kudzikisa kurwara."

Asi, sekune zvakawanda muhupenyu (ugh, kufambidzana), nguva ndizvo zvese. "Zvinotora vhiki mbiri kuti vanhu vane COVID-19 vagadzire vega masoja ekudzivirira chirwere aya," anotsanangura kudaro Dr. Stoneman. "Kana convalescent plasma ikapihwa nguva yekurwara, inogona kupfupisa nguva yekurwara uye kudzivirira varwere kubva pakurwara zvakanyanya, ”Saka, kunyangwe kutsvagurudza kuchiri kudiwa kuti uone kushanda kwekurapwa kweplasma, chirwere chazvino ndechekuti murwere paanotanga kurapwa, ndipo pavanoona mibairo yakanaka. (Zvakabatana: Maitiro Ekuita Nehutano Kuzvidya Mwoyo Munguva yeCOVID-19, uye Kupfuura)

Ndiani Anogona Kupa Convalescent Plasma yeCOVID-19?

Kufanirwa nhamba yekutanga: wanga uine coronavirus uye une bvunzo yekuzviratidza.

"Vanhu vanogona kupa plasma kana vaine hutachiona hweCCIDID-19 nemagwaro emurabhoritari (kungave nasopharyngeal [nasal] swab kana kuti antibody test), vakapora zvizere, uye vari asymptomatic kweanenge mavhiki maviri," sekureva Hyunah Yoon, MD, chirwere chinotapukira nyanzvi paAlbert Einstein Koreji yeMishonga. (Onawo verenga: Ko Positive Anti-Body Test Inomborevei?)

Hauna kuongororwa kwakasimbiswa asi uine chivimbo chekuti wakasangana nezviratidzo zvecoronavirus? Nhau dzakanaka: Unogona kuronga bvunzo yeantibody paunzvimbo yako yeAmerican Red Cross uye, kana mhedzisiro yacho yakanaka kune maantibhakitiriya, enderera zvinoenderana - ndiko kuti, chero bedzi uchinge wasangana nezvimwe zvinodiwa nevanopa, sekusava nezviratidzo. kwemazuva gumi nemana asati apiwa. Kunyange mavhiki maviri asina zviratidzo achikurudzirwa neDFA, zvimwe zvipatara nemasangano zvinogona kuda kuti vanopa vasave nechiratidzo chemazuva makumi maviri nemasere, anodaro Dr. Grossman

Kupfuura izvozvo, iyo American Red Cross inodawo kuti vanopa mari yeplasma vangangoita makore gumi nematanhatu, vanorema 110 lbs, uye vasangane nesangano rekupa ropa zvinodiwa. (Ona gwara iri rekupa ropa kuti uone kana wakanakira kuenda zvichibva pane izvo zvinodiwa.) Zvakakosha kuziva kuti panguva dzisiri dzedenda, unokwanisa (uye, TBH, unofanira) kupawo plasma kuti ishandiswe kumwe kurapa kwe, taura, varwere vegomarara uye vanopisa uye nenjodzi, maererano neNew York Blood Center.

Chii Chinogadziriswa Plasma Mupiro?

Kana uchinge waronga kushanya nenzvimbo yako yekupa zvipo, yave nguva yekugadzirira. Zvose zvinosanganisira, zvisinei, kunwa mvura yakawanda (inenge 16oz.) uye kudya mapuroteni-uye chikafu chine iron-yakapfuma (nyama tsvuku, hove, nyemba, sipinashi) maawa anotungamira pakugadzwa kwako kudzivirira kupera simba, kuchena, uye. dzungu, maererano neAmerican Red Cross.

Inzwi rakajairika? Izvi zvinodaro nekuti plasma uye mupiro weropa zvakafanana - kunze kwechiitiko chekupa. Kana wakambopa ropa, unoziva kuti mvura inoyerera kubva muruoko rwako ichipinda mubhegi uye imwe yose inhoroondo. Kupa plasma zvakati wandei, kukanganisa, kuomarara. Munguva yekupa plasma-chete, ropa rinotorwa kubva kune rumwe ruoko uye rinotumirwa nemuchina wepamusoro-soro unounganidza plasma uye wodzosera masero matsvuku eropa nemaplatelet - pamwe neimwe hydrating saline (aka mvura yemunyu) - kudzoka mumuviri wako. Izvi zvakakosha sezvo plasma iri 92 muzana mvura, sekureva kweAmerican Red Cross, uye nzira yekupa inowedzera njodzi yako yekushayiwa mvura (zvimwe pane izvi pazasi). Maitiro ese emupiro anofanira kutora ingangoita awa nemaminitsi gumi nemashanu (ingori maminetsi gumi nemashanu pakureba kupfuura mupiro weropa chete), sekureva kweAmerican Red Cross.

Zvakare sekupa ropa, mhedzisiro yekupa plasma ishoma - mushure mezvose, unofanirwa kunge uine hutano hwakanaka hwese kuti ukwanise kutanga. Izvo zviri kutaurwa, sezvataurwa pamusoro apa, kupera simba kwemvura kunogoneka. Uye nechikonzero ichocho, zvakakosha kuti uwedzere kunwa kwako kwemvura pazuva (ma) rinotevera uye usiye kure nekusimudza zvinorema uye kurovedza muviri kwerinenge zuva rose. Uye usazvinetse pamusoro pekuti muviri wako uri kudonhedza zvimwe zvinwiwa zvakakosha, sezvazvinogona (uye zvichiita) kutsiva huwandu hweropa kana plasma mukati memaawa makumi mana nemasere.

Kana iri njodzi yako yeCOVID-19? Izvozvo hazvifanire kuva zvinonetsa pano. Nzvimbo zhinji dzekupa ropa dzinoitwa nekugadzwa chete kuti vaedze kusimudzira tsika dzakanakisa dzekudyidzana uye vakaisa dzimwe nzira dzekudzivirira sekutsanangurwa kwazvinoitwa neCenters for Disease Control and Prevention (CDC).

Mashoko ari munyaya iyi akarurama seye nguva yekudhinda. Sezvo zvigadziriso nezve coronavirus COVID-19 ichiramba ichichinja, zvinokwanisika kuti rumwe ruzivo uye kurudziro munyaya iyi zvachinja kubva pakatanga kuburitswa. Tinokukurudzira kuti uongorore nguva zhinji zviwanikwa zvakaita seCDC, iyo WHO, uye nedhipatimendi rako rezvehutano reveruzhinji kune yakanyanya-kudhara dhata uye kurudziro.

Ongororo ye