Zvese zvaunoda Kuti Uzive Nezve ADPKD

Zvemukati

• Zviratidzo zveADPKD
• Kurapa kweADPKD
• Zvimwe zvinokanganisa kurapwa kweADPKD
• Kuongorora kweADPKD
• Kuongororwa kweADPKD
• Zvinokonzera ADPKD
• Matambudziko
• Hupenyu hunotarisirwa uye maonero

Autosomal yakanyanya polycystic itsvo chirwere (ADPKD) chirwere chisingaperi chinokonzera kuti cysts ikure muitsvo.

Sangano reNational Institute of Diabetes and Digestive and Kidney Diseases rinoti rinobata vanhu vanofungidzirwa kuti muvanhu mazana mana kusvika mazana chiuru.

Verenga pamusoro kuti udzidze zvakawanda nezve iyo:

• zviratidzo
• zvinokonzera
• kurapwa

Zviratidzo zveADPKD

ADPKD inogona kukonzera zviratidzo zvakasiyana, kusanganisira:

• musoro
• kurwadziwa kumusana kwako
• kurwadziwa mumativi ako
• ropa mune yako weti
• kuwedzera kukura kwemudumbu
• pfungwa yekuzara mudumbu mako

Zviratidzo zvinowanzo kukura mukukura, pakati pemakore makumi matatu nemakumi mana emakore, kunyangwe ivo vanogona zvakare kuoneka pazera repamusoro. Mune zvimwe zviitiko, zviratidzo zvinoonekwa muhudiki kana kuyaruka.

Zviratidzo zveichi chiitiko zvinowanzo kuve zvinowedzera nekufamba kwenguva.

Kurapa kweADPKD

Iko hakuna kuzivikanwa kurapwa kweADPKD. Zvisinei, kurapwa kunowanikwa kubatsira kubatsira kubata chirwere pamwe nezvinogona kuitika.

Kuti ubatsire kudzora kukura kweADPKD, chiremba wako anogona kunyorera tolvaptan (Jynarque).

Ndiwo wega mushonga uyo Chakudya neDrug Administration (FDA) yakabvumidza zvakanyanya kurapa ADPKD. Uyu mushonga unogona kubatsira kunonoka kana kudzivirira itsvo kutadza.

Zvichienderana nemamiriro ako chaiwo uye zvido zvekurapwa, chiremba wako anogona zvakare kuwedzera chimwe kana zvimwe zvezvinotevera kuchirongwa chako chekurapa:

• mararamiro anochinja kubatsira kudzikisa BP uye kusimudzira hutano hwetsvo
• mishonga yekubatsira kudzikisa kukanda kweropa, kubvisa marwadzo, kana kurapa hutachiona hunogona kuitika muitsvo, urineti, kana dzimwe nzvimbo.
• kuvhiya kubvisa ma cysts ari kukonzera kurwadziwa kwakanyanya
• kunwa mvura muswere wese wezuva uye kudzivirira caffeine kunonoka kukura kwecyst (vaongorori vari kudzidza kuti hydration inobata sei ADPKD)
• kudya zvidimbu zvidiki zvepuroteni yemhando yepamusoro
• kudzikamisa munyu, kana sodium, mukudya kwako
• kudzivisa potasiamu yakawandisa uye phosphorus mukudya kwako
• kudzikisira kunwa doro

Kugadzirisa ADPKD uye kunamatira nehurongwa hwako hwekurapa kunogona kunetsa, asi zvakakosha pakudzora kufambira mberi kwechirwere.

Kana chiremba wako akaraira tolvaptan (Jynarque), iwe uchafanirwa kugara uine bvunzo kuti uongorore hutano hwechiropa chako nekuti mushonga unogona kukonzera kukuvara kwechiropa.

Chiremba wako achanyatsoongorora hutano hweitsvo dzako kuti aone kana mamiriro acho akagadzikana kana kufambira mberi.

Kana iwe ukaita kukundikana kweitsvo, iwe uchafanirwa kugamuchira dialysis kana kuisirwa itsvo kubhadhara iyo kurasikirwa kwekushanda kweitsvo.

Taura nachiremba wako kuti udzidze zvakawanda nezve nzira dzako dzekurapa, kusanganisira izvo zvinogona kubatsira, njodzi, uye mutengo wenzira dzakasiyana dzekurapa.

Zvimwe zvinokanganisa kurapwa kweADPKD

Mazhinji emishonga iyo chiremba wako anogona kufunga kubatsira kubata kana kubata ADPKD inotakura imwe njodzi yemhedzisiro.

Semuenzaniso, Jynarque inogona kukonzera nyota yakanyanyisa, kuita weti kakawanda, uye mune zvimwe zviitiko, zvakakomba kukuvara kwechiropa. Pakave nemishumo yekutadza kwakakomba kwechiropa kunoda kuisirwa chiropa mune vanhu vanotora Jynarque.

Mimwe mishonga inotarisa zvimwe zviratidzo zveADPKD inogona zvakare kukonzera mhedzisiro. Kuti udzidze zvakawanda nezve zvingangoitika mhedzisiro yekurapa kwakasiyana, taura nachiremba wako.

Kana iwe uchifunga kuti iwe unogona kunge wakagadzira mhedzisiro kubva pakurapwa, rega chiremba wako azive ipapo ipapo. Ivo vanogona kukurudzira shanduko kuchirongwa chako chekurapa.

Chiremba wako anogona zvakare kuraira bvunzo dzese paunenge uchiita mamwe marapirwo kuti uone zviratidzo zvekukuvara kwechiropa kana zvimwe zvinokanganisa.

Kuongorora kweADPKD

Polycystic itsvo chirwere (PKD) chirwere chemagene.

Kuongororwa kweDNA kunowanikwa, uye kune marudzi maviri ebvunzo.

• Gene kubatanidza kuyedzwa. Iyi bvunzo inoongorora mamwe mamaki muDNA yenhengo dzemhuri dzine PKD. Inoda masampuli eropa kubva kwauri pamwe nenhengo dzinoverengeka dzemhuri dzinokanganiswa uye dzisingabatwe nePKD.
  
• Direct mutation ongororo / DNA kuteedzana. Uyu muedzo unoda chete sampuro imwe kubva kwauri. Iyo inonyatsoongorora iyo DNA yemhando dzePKD.

Kuongororwa kweADPKD

Kuti uongorore ADPKD, chiremba wako achakubvunza nezve:

• zviratidzo zvako
• nhoroondo yezvekurapa
• nhoroondo yemhuri yekurapa

Vanogona kuraira iyo ultrasound kana imwe bvunzo yekufungidzira kuti utarise ma cysts uye zvimwe zvinogona kukonzera zviratidzo zvako.

Ivo vanogona zvakare kuraira kwemajini kuongorora kuti udzidze kana iwe uine geneti mutation inokonzeresa ADPKD. Kana iwe uine iro rakakanganiswa geni uye zvakare uine vana, ivo vanogona kuvakurudzira ivo kuti vawane kuongorororwa kwemajini futi.

Zvinokonzera ADPKD

ADPKD inhaka inogarwa nhaka.

Muzviitiko zvakawanda, zvinobva mukuchinja kweiyo PKD1 geni kana PKD2 geni.

Kugadzira ADPKD, munhu anofanirwa kuve nekopi imwe yeiyo yakabatwa geni. Ivo vanowanzo gara rakakanganisika geni kubva kune mumwe wevabereki vavo, asi mune zvisingawanzoitika zviitiko, iyo geni mutation inogona kuitika zvega.

Kana iwe uine ADPKD uye mumwe wako asina uye iwe wafunga kutanga mhuri pamwechete, vana vako vangave nemakumi mashanu muzana mukana wekuvandudza chirwere.

Matambudziko

Mamiriro acho zvakare anokuisa iwe panjodzi yezvinetso, senge:

• BP
• Urinary turakiti hutachiona
• cysts pachiropa chako kana chirwatata
• asina kujairika moyo mavharuvhu
• uropi aneurysm
• itsvo kutadza

Hupenyu hunotarisirwa uye maonero

Hupenyu hwako hunotarisirwa uye maonero neADPKD zvinoenderana nezvinhu zvinoverengeka, zvinosanganisira:

• iyo chaiyo genetic mutation iri kukonzera ADPKD
• chero matambudziko aunowana
• marapirwo aunogashira uye kuti unonamira zvakadii kuchirongwa chako chekurapa
• hutano hwako hwese uye mararamiro

Taura nachiremba wako kuti udzidze zvakawanda nezve mamiriro ako uye maonero. Kana ADPKD ichionekwa kutanga uye ikatarisirwa nemazvo, vanhu vanowanzo kwanisa kuchengetedza hupenyu huzere, hunoshanda.

Semuenzaniso, vanhu vazhinji vane ADPKD vachiri kushanda pavanenge vaonekwa vanokwanisa kuenderera mberi nebasa ravo.

Kudzidzira maitiro ane hutano uye kutevedzera chirongwa chako chekurapa chakakurudzirwa nachiremba kunogona kubatsira kudzivirira matambudziko uye kuchengeta itsvo dzako dzive noutano kwenguva refu.