Chii chinonzi GH bvunzo uye uye chinodiwa riinhi

Zvemukati

• Chii ichochi
• Zvinoitwa sei

Kukura kwehormone, inonziwo GH kana somatotropin, yakakosha kemikari inogadzirwa neyepituitary gland inoshanda mukukura kwevana nevechiri kuyaruka uye zvakare inobata mumitezo yemetabolism yemuviri.

Bvunzo iyi inoitwa nemuyero mumasampuli eropa akaunganidzwa murabhoritari uye inowanzo kumbirwa neyemugumo wezvemagetsi kana paine fungidziro yekushomeka kweGH kugadzirwa, kunyanya muvana vanounza kukura pazasi pekutarisirwa, kana kunyanyisa kugadzirwa kwayo , yakajairika mugigantism kana acromegaly.

Iko kushandiswa kweGH semushonga kunoratidzwa kana paine kushomeka mukugadzirwa kwehomoni iyi, muvana kana vakuru, sekuratidzwa nachiremba. Kuti udzidze zvakawanda nezve mashandisiro ayo, mitengo uye mhedzisiro yekukura kwehomoni, tarisa chinyorwa chehomoni GH.

Chii ichochi

Chiyero cheGH chinokumbirwa kana iwe uchifungidzira:

• Dwarfism, ndiko kushomeka kwekukura kwehormone muvana, zvichikonzera hupfupi. Nzwisisa kuti chii uye chii chinogona kukonzera kudzikisira;
• Munhu mukuru GH kushomeka, inokonzerwa nekugadzirwa kweGH pazasi peyakajairwa, iyo inotungamira kune zviratidzo sekuneta, kuwedzera mafuta mashoma, kudzikira kuonda, kudzikira kugona kurovedza muviri, kuderedzwa kwefupa kuwanda uye kuwedzera njodzi yekuvandudza chirwere chemoyo.
• Gigantism, inoratidzirwa nekuwedzeredza kweGH kuchengetedzwa mumwana kana kuyaruka, zvichikonzera kuwedzeredza kukura;
• Acromegaly, inova chirwere chinokonzerwa nekuwedzeredza kweGH muvanhu vakuru, zvichikonzera shanduko pakuonekwa kweganda, maoko, tsoka uye kumeso. Onawo mutsauko uripo pakati peacromegaly uye gigantism;

Kushaikwa kweGH mumuviri kunogona kuve nezvakakonzera zvinoverengeka, zvakadai sehosha dzechibereko, shanduko dzehuropi, senge mamota, hutachiona kana kuzvimba kana nekuda kwemhedzisiro yechemo kana radiation radiation, semuenzaniso. Kuwedzeredza kweGH, kune rumwe rutivi, kazhinji kunoitika nekuda kwepituitary adenoma.

Zvinoitwa sei

Kuyerwa kweGH hormone kunoitwa nekuongorora masampuli eropa murabhoritari uye kunoitwa munzira mbiri:

1. Baseline GH kuyerwa: zvinoitwa neinenge maawa matanhatu ekutsanya kwevana uye maawa masere evachiri kuyaruka nevakuru, inoongorora huwandu hwehormone iyi muyenzaniso yeropa mangwanani;
2. GH kukurudzira bvunzo (ine Clonidine, Insulin, GHRH kana Arginine): zvinoitwa nekushandiswa kwemishonga inogona kukurudzira GH kuchengetedzwa, kana paine fungidziro yekushaikwa kwehomoni iyi. Tevere, kuongororwa kweropa GH kuongororwa kunoitwa mushure memaminitsi makumi matatu, makumi matanhatu, makumi mapfumbamwe nemakumi mapfumbamwe nemakumi maviri ekushandisa mushonga.

Iyo GH yekumutsa bvunzo inodikanwa nekuti kugadzirwa kweGH hormone nemuviri hakusi yunifomu, uye kunogona kupindirwa nezvinhu zvinoverengeka, sekutsanya, kushushikana, kurara, kutamba mitambo kana kana huwandu hweshuga muropa inodonha. Nekudaro, mimwe yemishonga inoshandiswa ndeye Clonidine, Insulin, Arginine, Glucagon kana GHRH, semuenzaniso, izvo zvinokurudzira kana kudzivisa kugadzirwa kwehomoni.

Uye zvakare, chiremba anogona zvakare kuraira kumwe kuyedzwa, senge kuyerwa kwemahormone senge IGF-1 kana IGFBP-3 protein, iyo inoshanduka nekusiyana kweGH: MRI scan yehuropi, kuongorora shanduko yegland pituitary, zvakare zvinogona kubatsira kuziva chakakonzera dambudziko.