Fecal Transplants: Iyo Kiyi Yekuvandudza Gut Hutano?

Zvemukati

• Chii chinonzi fecal kuisazve?
• Zvinoitwa sei?
• Colonoscopy
• Enema
• Nasogastric chubhu
• Kamudzira
• Zvinokonzera chero mhedzisiro here?
• Chituru chinobva kupi?
• Ndeapi mabhenefiti ekurapa C. Diff hutachiona?
• Zvakadiniko nezve mabhenefiti kune mamwe mamiriro?
• Irritable bowel syndrome (IBS)
• Ulcerative colitis (UC)
• Autism spectrum kusagadzikana (ASD)
• Kuonda
• Ndiani asingafanire kutora fecal kuisirwa?
• Ndeipi mamiriro eDAA?
• Zvakadii nezve DIY fecal transplants?
• Chinokosha

Chii chinonzi fecal kuisazve?

Kuchekesa fecal inzira inoendesa chigaro kubva kune anomupa kuenda kudumbu (GI) remumwe munhu nechinangwa chekurapa chirwere kana mamiriro. Inonzi zvakare fecal microbiota transplant (FMT) kana bacteriotherapy.

Ivo vari kuve vachiwedzera kuve vanozivikanwa sezvo vanhu vanova vanoziva zvakanyanya nekukosha kweiyo gut microbiome. Pfungwa yekusimudzira fecal ndeyekuti ivo vanobatsira kuunza mabhakitiriya anobatsira mune rako GI turakiti.

Nekudaro, aya mabhakitiriya anobatsira anogona kubatsira kurwisa hwakawanda hwehutano mamiriro, kubva kuGI kutapukirwa kune autism spectrum kusagadzikana (ASD).

Zvinoitwa sei?

Kune nzira dzinoverengeka dzekuita tsvina, imwe neimwe iine mabhenefiti avo.

Colonoscopy

Iyi nzira inoburitsa gadzi remvura yekugadzirira yakananga mukati mako ura hukuru kuburikidza nekolonoscopy. Kazhinji, iyo colonoscopy chubhu inosundirwa kuburikidza nehumwe hwese hwako hukuru hutumbu. Sezvo chubhu painobuda, inoisa iyo yekuisa mukati mako ura.

Kushandisa colonoscopy kune mukana wekubvumidza vanachiremba kuti vafungidzire nzvimbo dzemukati mako matumbu anogona kukuvara nekuda kwechimiro chiri pasi.

Enema

Kufanana nekolonoscopy nzira, iyi nzira inosvitsa iyo yekuisa yakananga mukati mako ura hukuru kuburikidza neemaema.

Iwe unogona kukumbirwa kuti urare parutivi rwako apo muviri wako wepasi wakasimudzwa. Izvi zvinoita kuti zvive nyore kuti kuiswa kwacho kusvike ura hwako. Tevere, girizi rakaiswa enema tip inoiswa zvinyoro nyoro mukati meyako rectum. Iyo yekudyara, iri muhomwe yeemaema, inobvumidzwa kuyerera ichipinda mukati meye rectum.

Kufungidzira kweececal kwakapihwa neemaema kazhinji hakukuvadze uye kwakaderera mumutengo kupfuura colonoscopies.

Nasogastric chubhu

Mune maitiro aya, gadziriro yemvura inogadziriswa inoendeswa mudumbu rako kuburikidza nechubhu inomhanya nemumhino dzako. Kubva mudumbu rako, chishandiso chinobva chaenda kumatumbu ako.

Kutanga, iwe unozopihwa mushonga wekumisa dumbu rako kuburitsa asidhi iyo inogona kuuraya zvisikwa zvinobatsira mukugadzirira kwekuisa.

Tevere, iyo chubhu inoiswa mumhino dzako. Asati maitiro acho, nyanzvi yehutano anoongorora kuiswa kwechubhu uchishandisa imaging tekinoroji. Kana yangoiswa zvakanaka, vanoshandisa jekiseni kufuratira gadziriro kuburikidza nehubhu uye mudumbu rako.

Kamudzira

Iyi inzira nyowani yekutsvaira fecal iyo inosanganisira kumedza akati wandei emapiritsi ane chigaro chekugadzirira. Zvichienzaniswa nedzimwe nzira, ndozvishoma zvinokanganisa uye zvinogona kuitirwa muhofisi yezvokurapa kana kunyangwe kumba.

A 2017 akafananidza iyi nzira kune colonoscopy mune vanhu vakuru inodzokororwa Clostridium difficile hutachiona. Iyo capsule haina kuratidzika kunge isinganyanyo shanda kupfuura colonoscopy maererano nekudzivirira kudzokororwa kwehutachiona kweanenge gumi nemaviri masvondo.

Zvakadaro, nzira iyi yekumedza makaputuru inoda kuenderera mberi nekudzidza kuti unzwisise kushanda kwayo nekuchengeteka.

Zvinokonzera chero mhedzisiro here?

Kutevera fecal kuisirwa, iwe unogona kusangana nemimwe mhedzisiro, kusanganisira:

• kusagadzikana mudumbu kana kupwanya
• kuvimbiswa
• kuzvimba
• manyoka
• belching kana kubirira

Bata wako mupi wezvehutano ipapo kana marwadzo akanyanya kana iwe uchinge wawanawo:

• zvakanyanya kuzvimba mudumbu
• kurutsa
• ropa mune chako chigaro

Chituru chinobva kupi?

Chituru chinoshandiswa mukusimudzira tsvina chinobva kune vane hutano vanhu vanopa. Zvichienderana nemaitiro, chigaro chinogadzirwa kuita mhinduro yemvura kana kuomeswa kuita girandi.

Vanogona kupa vanofanirwa kuyedzwa kwakasiyana siyana, kusanganisira:

• kuongororwa kweropa kutarisa hepatitis, HIV, uye mamwe mamiriro
• zvituru bvunzo uye tsika kuti utarise utachiona uye zvimwe zviratidzo zvechinhu chiri pasi

Vanopa vanoendawo kuburikidza nehurongwa hwekuongorora kuti vaone kana ivo:

• vakatora mishonga inorwisa mabhakitiriya mumwedzi mitanhatu yapfuura
• vane immune system yakadzikama
• vane nhoroondo yehutachiwana hwepabonde, kusanganisira kusangana pasina kudzivirira zvipingamupinyi
• akagamuchira tattoo kana kuboora muviri mumwedzi mitanhatu yadarika
• vane nhoroondo yekushandisa zvinodhaka
• achangobva kuenda kunyika dzine huwandu hwakawanda hwehutachiona hwehutachiona
• vane chirwere chisingaperi cheGI, chakadai sekuputira ura chirwere

Unogona kusangana nemawebhusaiti anopa fecal sampuli netsamba. Kana iwe uri kufunga nezve fecal kuisirwa, ita shuwa yekushanda pamwe nemupi wako wezvehutano mupi kuti uve nechokwadi chekuti uri kuwana muyenzaniso kubva kune anokwanisa mupi.

Ndeapi mabhenefiti ekurapa C. Diff hutachiona?

C. zvakasiyanahutachiona hunozivikanwa nekunetseka kurapa. Nezve vanhu vanorapwa nemishonga inorwisa mabhakitiriya kune a C. zvakasiyana hutachiona hunoenderera mberi nekuvandudza hutachiona hunodzokororwa. Uyezve, kurwisa mabhakitiriya mukati C. zvakasiyana yanga ichiwedzera.

C. zvakasiyana hutachiona hunoitika kana paine kuwanda kwebhakitiriya mune yako GI turakiti. Sekureva kweAmerican College yeGastroenterology, 5 kusvika 15 muzana yevakuru vane hutano - uye 84.4 muzana yevana vachangozvarwa uye vacheche vane hutano - vane huwandu hwakaenzana C. zvakasiyana mumatumbu avo. Izvo hazvikonzere matambudziko uye zvinobatsira mukuchengetedza zvakajairika hutachiona huwandu hwemukati.

Zvisinei, mamwe mabhakitiriya mumatumbo ako anowanzo chengetedza huwandu hwe C. zvakasiyana mukutarisa, kuchidzivirira kubva mukukonzera hutachiona. Kuisirwa fecal kunogona kubatsira kudzosera aya mabhakitiriya mune yako GI turakiti, ichivabvumira kudzivirira kuwanda kweramangwana kwe C. zvakasiyana.

Zvizhinji zvezvidzidzo zviripo nezve mashandisirwo ezvekushambadzira kwekurapa kwe C. zvakasiyana hutachiona hushoma. Nekudaro, mazhinji akaburitsa mhedzisiro yakafanana inoratidza chiyero chekurapa chinopfuura.

Zvakadiniko nezve mabhenefiti kune mamwe mamiriro?

Nyanzvi dzichangobva kutsvagurudza kuti fecal transplants inogona kubatsira sei nemamwe mamiriro uye nenyaya dzehutano, kusanganisira mamwe mamiriro eGI. Pazasi pane mufananidzo weimwe yekutsvaga kusvika ikozvino.

Nepo mimwe yemhedzisiro iyi ichivimbisa, pachine chikonzero chakakura chekutsvagisa munzvimbo ino kuona kushanda pamwe nekuchengetedzeka kwezvinoisirwa fecal kune izvi zvinoshandiswa.

Irritable bowel syndrome (IBS)

Imwe ongororo ichangoburwa yezviongororwa zvipfumbamwe yakawana kuti fecal transplants yakavandudza zviratidzo zveBS mune zvevatori vechikamu. Nekudaro, izvo zvipfumbamwe zvidzidzo zvaive zvakasiyana kwazvo munzira yavo, chimiro, uye kuongorora.

Ulcerative colitis (UC)

Miedzo mina yaive ichifananidza UC kuregererwa kwemitengo muvanhu vaive vagamuchira fecal kuisirwa maringe ne placebo. Vaya vakagashira tsvina vakawana kuregererwa kwemazana makumi maviri neshanu muzana, zvichienzaniswa ne5 muzana yeavo vari muboka re placebo.

Ramba uchifunga kuti kuregererwa kunoreva nguva yenguva isina zviratidzo. Vanhu vane UC vari mukuregererwa vanogona kuramba vachienderera mberi kuti vave neramangwana remoto kana zviratidzo.

Autism spectrum kusagadzikana (ASD)

Chishoma chakawanikwa kuti yakawedzera fecal yekuisa regimen inogara kwemavhiki manomwe kusvika masere yakadzikisa zviratidzo zvekugaya muvana vane ASD. Maitiro ekuzvibata eASD akaonekwa achivandudza futi.

Idzi gadziridzo dzaive dzichionekwa vhiki sere mushure mekurapwa.

Kuonda

Nguva pfupi yadarika mumakonzo aisanganisira mapoka maviri: mumwe akadyisa chikafu chakakora-mafuta uye mumwe akadyisa chikafu chemafuta akajairwa uye akaiswa pachirongwa chekurovedza muviri.

Iyo mbeva pane yakakwira-mafuta chikafu yakagashira tsvina kubva kumakonzo muboka repiri. Izvi zvakaonekwa sekudzora kuzvimba uye kugadzirisa metabolism. Vakatotarisa hutachiona hwakati wandei hune hukama nemhedzisiro iyi, asi hazvisi pachena kuti mhedzisiro iyi inoshandura sei muvanhu.

Verenga zvimwe nezve kubatana pakati pehuremu uye gut mabhakitiriya.

Ndiani asingafanire kutora fecal kuisirwa?

Fecal transplants haina kukurudzirwa kune vanhu vasina immunocompromised nekuda kwe:

• mishonga inodzvinyirira immune immune
• HIV
• yakakwira chiropa chirwere, senge cirrhosis
• ichangoburwa yemongo yemapfupa

Ndeipi mamiriro eDAA?

Nepo kutsvagurudza kwakatenderedza fecal transplants kuri kuvimbisa, iyo Kudya neDrug Administration (FDA) haina kuvabvumidza kune chero kiriniki yekushandisa uye inovaona semushonga wekutsvaga.

Pakutanga, vanachiremba vaida kushandisa fecal transplants vaifanira kunyorera kune FDA vasati vaita maitiro. Izvi zvaisanganisira nzira yakareba yekutenderwa iyo yaiodza moyo vazhinji kubva pakushandisa tsvina.

Iyo FDA yakasunungura ichi chinodikanwa chekusanganisa fecal inoitirwa kurapa ichidzokororwa C. zvakasiyana hutachiona husina kupindura kumishonga inorwisa mabhakitiriya. Asi vanachiremba vachiri kufanira kunyorera chero kwekushandisa kunze kwechiitiko ichi.

Zvakadii nezve DIY fecal transplants?

Iyo internet izere nezve maitiro ekuita fecal kuisirwa kumba. Uye nepo nzira ye DIY inganzwika senzira yakanaka yekutenderera mirau yeDAA, kazhinji haisi zano rakanaka.

Heano zvikonzero zvishoma nei.

• Pasina kukodzera kuongororwa kwevanopa, unogona kunge uri kuzviisa panjodzi yekubatira chirwere.
• Vanachiremba vanoita fecal transplants vane yakadzidziswa nzira yekuchengeteka kwechigaro kugadzirira kuisazve.
• Tsvagurudzo yemhedzisiro-yenguva refu mhedzisiro uye kuchengetedzeka kweiyo fecal transplants ichiri mashoma, kunyanya kune mamwe mamiriro asiri C. zvakasiyana hutachiona.

Chinokosha

Fecal transplants inovimbisa inogona kurapwa kurapwa kweakawanda mamiriro. Nhasi, ivo vanonyanya kushandiswa kurapa zvichidzokororwa C. zvakasiyana zvirwere.

Sezvo nyanzvi dzichidzidza zvakawanda nezve fecal transplants, ivo vanogona kuve sarudzo kune mamwe mamiriro, kubva kuGI nyaya kune mamwe mamiriro ekuvandudza.