Munyori: Lewis Jackson
Zuva Rekusika: 6 Chivabvu 2021
Gadziridza Zuva: 17 Mbudzi 2024
Anonim
Gigantism & Acromegaly | Growth Hormone, Signs & Symptoms, Diagnosis, Treatment
Vhidhiyo: Gigantism & Acromegaly | Growth Hormone, Signs & Symptoms, Diagnosis, Treatment

Zvemukati

Chii chinonzi Gigantism?

Gigantism chiitiko chisingawanzo chinokonzera kukura kwakasarudzika muvana. Shanduko iyi inonyanya kuzivikanwa maererano nehurefu, asi girth rinokanganiswa futi. Izvo zvinoitika kana mwana wako wepituitary gland achigadzira yakawandisa kukura kwehormone, iyo inozivikanwawo se somatotropin.

Kutanga kuongororwa kunokosha. Kukurumidza kurapwa kunogona kumisa kana kunonoka shanduko dzinogona kukonzera mwana wako kukura kukura kupfuura zvakajairwa. Zvisinei, mamiriro acho anogona kuomera vabereki kuti vaone. Zviratidzo zvegigantism zvingaite senge zvakajairika kukura kwevana kukura pakutanga.

Chii chinokonzera gigantism?

Pituitary gland bundu rinowanzo kuve iro rinokonzeresa gigantism. Iyo pea-saizi pituitary gland iri pazasi pehuropi hwako. Inoita mahormone anodzora akawanda mabasa mumuviri wako. Mamwe mabasa anotarisirwa negland anosanganisira:

  • kudzora kwekushisa
  • kukura pabonde
  • kukura
  • metabolism
  • kugadzirwa kweweti

Kana bundu rikakura pane iyo pituitary gland, iyo gland inogadzira yakakura kwazvo kukura hormone kupfuura inoda muviri.


Kune zvimwe zvikonzero zvisingawanzoitika zvegigantism:

  • McCune-Albright syndrome inokonzeresa kukura kwakasarudzika mumabonzo emapfupa, zvigamba zveganda-shava ganda, uye gland kusagadzikana.
  • Carney yakaoma chiitiko chakagarwa nhaka chinokonzeresa mamota asina kubatika pane anobatana matishu, ane gomarara kana asiri eancancerous endocrine mamota, uye mavara eganda rakasviba.
  • Multiple endocrine neoplasia mhando 1 (MEN1) chirwere chakagarwa nhaka chinokonzeresa mamota mupitu gland, pancreas, kana parathyroid gland.
  • Neurofibromatosis chirwere chakagarwa nhaka chinokonzeresa mamota muhurongwa hwetsinga.

Kuziva zviratidzo zvegigantism

Kana mwana wako aine gigantism, iwe unogona kuona kuti ivo vakakura kwazvo kupfuura vamwe vana vezera rimwe chete. Zvakare, zvimwe zvikamu zvemuviri wavo zvinogona kuve zvakakura zvakaenzana nezvimwe zvikamu. Zviratidzo zvakajairika zvinosanganisira:

  • maoko nemakumbo akakurisa kwazvo
  • zvigunwe zvakakora nezvigunwe
  • shaya yakatanhamara nehuma
  • mafasha kumeso maficha

Vana vane gigantism vanogona zvakare kuve nemhete dzakapetana uye misoro mikuru, miromo, kana rurimi.


Zviratidzo izvo mwana wako anazvo zvinoenderana nehukuru hwepituitary gland bundu. Sezvo bundu rinokura, rinogona kumanikidza tsinga dziri muuropi. Vanhu vazhinji vanorwadziwa nemusoro, matambudziko ekuona, kana kusvotwa kubva mumamota munzvimbo ino. Zvimwe zviratidzo zvegigantism zvinogona kusanganisira:

  • vangadikitira zvakanyanya
  • kurwadziwa kwakanyanya kana kudzokororwa
  • kushaya simba
  • kushaya hope uye kumwe kurara
  • kunonoka kuyaruka muvakomana nevasikana
  • kumwedzi kumwedzi kwevanasikana
  • matsi

Ko gigantism inoonekwa sei?

Kana chiremba wemwana wako achifungidzira gigantism, vanogona kukurudzira kuongororwa kweropa kuyera huwandu hwehomoni dzekukura uye insulin-senge kukura chinhu 1 (IGF-1), inova hormone inogadzirwa nechiropa. Chiremba zvakare anogona kukurudzira bvunzo yeglucose yekushivirira bvunzo.

Munguva yemuromo wemuromo glucose shiviriro bvunzo, mwana wako anonwa chakakosha chinwiwa chine glucose, rudzi rwehuga. Ropa sampuli dzinozotorwa pamberi uye mushure mekunge mwana wako amwa chinwiwa.


Mumuviri wakajairwa, huwandu hwehormone yekukura inodonha mushure mekudya kana kunwa glucose. Kana nhanho dzemwana wako dzikaramba dzakafanana, zvinoreva kuti muviri wavo uri kuburitsa yakawandisa mahormone.

Kana bvunzo dzeropa dzichiratidza gigantism, mwana wako anozoda MRI scan yeiyo pituitary gland. Vanachiremba vanoshandisa iyi scan kuti vawane bundu uye vaone kukura uye chinzvimbo.

Ko gigantism inobatwa sei?

Kurapa kwegigantism kunovavarira kumisa kana kunonoka kugadzirwa kwemwana wako mahormone ekukura.

Kuvhiya

Kubvisa bundu ndiyo nzira inosarudzika yekurapa gigantism kana chiri icho chikonzero chiri kukonzera.

Chiremba anovhiya anosvika pabundu nekuita cheki mumhino dzemwana wako. Maikorosikopu kana makamera madiki anogona kushandiswa kubatsira chiremba anovhiya kuti aone bundu riri mugland. Muzviitiko zvakawanda, mwana wako anofanira kukwanisa kudzokera kumba kubva kuchipatara zuva rakatevera rekuvhiyiwa.

Mishonga

Mune zvimwe zviitiko, kuvhiya kungasave sarudzo. Semuenzaniso, kana paine mukana wakakura wekukuvara kune yakakosha ropa mudziyo kana tsinga.

Chiremba wemwana wako anogona kukurudzira mushonga kana kuvhiya isiri sarudzo. Iyi kurapwa inoitirwa kuderedza bundu kana kumisa kugadzirwa kweakawandisa kukura kwehomoni.

Chiremba wako anogona kushandisa mishonga octreotide kana lanreotide kudzivirira kukura kwehomoni. Iyi mishonga inoteedzera imwe hormone iyo inomisa kukura kwehomoni kugadzirwa. Vanowanzo kupihwa sejekiseni kanenge kamwe pamwedzi.

Bromocriptine uye cabergoline mishonga inogona kushandiswa kudzikisa kukura kwemahormone. Izvi zvinowanzo kupihwa mupiritsi fomu. Dzinogona kushandiswa ne octreotide. Octreotide inogadzira mahormone ayo, kana akajowa, anogona zvakare kudzikisa iwo mazinga ekukura mahormone uye IGF-1.

Mumamiriro ezvinhu apo iyi mishonga isingabatsire, kupfura kwezuva nezuva kwepegvisomant kunogona kushandiswa zvakare. Pegvisomant mushonga unovhara mhedzisiro yekukura kwemahormone. Izvi zvinoderedza nhanho dze IGF-1 mumuviri wemwana wako.

Gamma banga redhiyo

Gamma banga redhiyo ndiyo sarudzo kana chiremba chemwana wako achitenda kuti kuvhiya kwechinyakare hazviite.

"Gamma banga" muunganidzwa wematanda emwaranzi akatarisa zvakanyanya. Aya matanda haakuvadze nyama dzakakomberedza, asi anokwanisa kuendesa simba rine simba remwaranzi panguva iyo pavanosanganisa nekurova bundu. Iyi dose inokwana kuparadza bundu.

Gamma banga kurapwa kunotora mwedzi kusvika makore kuti inyatso shanda uye kudzosera iwo mazinga ekukura kwehormoni kune akajairwa. Inoitwa pasipatient hwaro pasi pechirwere.

Zvisinei, sezvo mwaranzi yerudzi urwu rwekuvhiya yakabatanidzwa nekufutisa, kuremara pakudzidza, uye nenyaya dzemanzwiro muvana, zvinowanzo shandiswa chete kana dzimwe nzira dzekurapa dzisingashande.

Marefu-marefu maonero evana vane gigantism

Sekureva kweSt.Joseph's Hospital neMedical Center, makumi masere muzana ezviitiko zvegigantism zvinokonzerwa nerudzi rwakanyanya rwepituitary bundu rinorapwa nekuvhiyiwa. Kana bundu rikadzoka kana kana kuvhiya kusingagoni kuyedzwa zvakachengeteka, mishonga inogona kushandiswa kudzikisa zviratidzo zvemwana wako uye kuvabvumidza kuti vararame hupenyu hwakareba uye hunogutsa.

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