Munyori: Monica Porter
Zuva Rekusika: 15 Kurume 2021
Gadziridza Zuva: 18 Mbudzi 2024
Anonim
H2 Receptor Blockers - Pharmacology
Vhidhiyo: H2 Receptor Blockers - Pharmacology

Zvemukati

Kurega RANITIDINE

Muna Kubvumbi 2020, iyo yakakumbirwa kuti ese mafomu ekunyora uye pamusoro-the-counter (OTC) ranitidine (Zantac) abviswe mumusika weU.S. Uku kurudziro kwakaitwa nekuti mwero usingagamuchirike weNDMA, inogona kuitika carcinogen (kenza inokonzera kenza), yakawanikwa mune zvimwe zvigadzirwa zveRititidine. Kana iwe wakarairwa ranitidine, taura nachiremba wako nezve dzimwe nzira dzakachengeteka usati wamisa mushonga. Kana iwe uri kutora OTC ranitidine, rega kutora mushonga uye taura nemupi wako wekuchengeta hutano nezve dzimwe sarudzo. Panzvimbo pekutora zvisina kushandiswa ranitidine zvigadzirwa kunzvimbo yemushonga yekudzosa, vasiye maererano nemirairo yechigadzirwa kana nekutevera iyo FDA's.

Chii chinonzi H2 Receptor Blockers?

H2 receptor blockers iri kirasi yemishonga inogona kushandiswa kurapa mamiriro anokonzera kuwanda kwemudumbu acid. Iyi mishonga inowanikwa pamusoro pekambani uye nemishonga. Kazhinji H2 receptor blockers anosanganisira:

  • nizatidine (Axid)
  • famotidine (Pepcid, Pepcid AC)
  • cimetidine (Tagamet, Tagamet HB)

H2 receptor blockers inowanzo shandiswa kurapa gastritis, kana kupisa mweya, uye kurapa maronda eronda. Peptic ulcers maronda anorwadza anoumba mukati memudumbu, mudumbu, kana duodenum, chinova chikamu chekutanga chemukati mudumbu. Ivo vanowanzo kukura semhedzisiro yekuzvimba uye yakawandisa mudumbu acid. Vanachiremba vanogona zvakare kukurudzira H2 receptor blockers kuti vachengetedze maronda eronda kuti asadzoke.


H2 receptor blockers inowanzo shandiswa kugadzirisa zviratidzo zvegastroesophageal Reflux chirwere (GERD). GERD chimiro chisingaperi cheacid reflux, iyo inokonzeresa acidic mudumbu mukati kuyerera ichidzokera kumusoro mudumbu. Kugara uchionekwa mudumbu asidhi kunogona kutsamwisa esophagus uye kutungamira kune zvisina kugadzikana zviratidzo, sekurwadziwa pamoyo, kusvotwa, kana kunetseka kumedza.

H2 blockers inogona zvakare kushandiswa kurapa mashoma maitiro akajairika senge Zollinger-Ellison syndrome, mamiriro anokonzeresa kugadzirwa kwemudumbu acid.

Vanachiremba vanogona zvakare kukurudzira H2 receptor blockers yekushandisa-isiri yekushandisa. Izvi zvinoreva kushandisa mushonga kurapa mamiriro asina kurapwa mvumo yekurapa. Semuenzaniso, H2 receptor blockers inogona kushandiswa kurapa matambudziko epancreatic kana kushandiswa mune zviitiko zvekusagadzikana, kunyangwe zvisiri zvechivanhu zvinoshandiswa izvi zvinangwa.

H2 Receptor Blockers Anoshanda Sei?

Paunotora H2 receptor blocker, izvo zvinoshanda zvinoshandiswa zvinoenda kune mamwe maresitoreti ari pamusoro pemasero emudumbu ayo anoburitsa acids. Mushonga unodzivirira kumwe kusangana kwemakemikari mumaseru aya kuitira kuti atadze kuburitsa asidhi yakawanda. Sekureva kweNational Institutes of Health, H2 receptor blockers inoderedza dumbu reacid secretions pamusoro peye 24-awa nguva ne70 muzana. Nekuderedza huwandu hweacid mudumbu, chero nyama dzakakuvadzwa dzinotenderwa nguva yekuporeswa.


Ndeapi Iwo Mhedzisiro Mhedzisiro yeH2 Receptor Blockers?

Mazhinji emhedzisiro anosangana neH2 receptor blockers ane hunyoro uye anowanzo dzikira semunhu anotora mushonga nekufamba kwenguva. Chete 1.5 muzana yevanhu vanomira kutora H2 receptor blockers nekuda kwemhedzisiro.

Mimwe yemhedzisiro inogona kuitika neH2 receptor blockers inosanganisira:

  • kuvimbiswa
  • manyoka
  • kunetseka kurara
  • muromo wakaoma
  • ganda rakaoma
  • kutemwa nemusoro
  • kurira munzeve
  • mhino inomhanya
  • kunetseka kuita weti

Fonera chiremba wako kana uine zvimwe zviratidzo zvaunofungidzira kuti zvinogona kunge zviri zvekutora H2 receptor blocker.

Muzviitiko zvisingawanzoitika, H2 receptor blockers inogona kukonzeresa zvakakomba mhedzisiro, senge:

  • blister, kupisa, kana kuwedzera ganda
  • shanduko pane zvakaratidzwa
  • kuvhiringidzika
  • kusagadzikana
  • kunetseka kufema
  • kurira
  • kuomesa pachipfuva
  • kurova kwemoyo zvisina kujairika
  • kuona zvisipo
  • pfungwa dzekuzviuraya

Shevedza chiremba wako kana kuenda kuchipatara ipapo kana iwe ukaona chero cheizvi zviratidzo.


Kunyangwe paine yavo mhedzisiro mhedzisiro, H2 receptor blockers inowanzo kuve inoshanda kurapwa kwemamiriro ezvinhu anokonzeresa zvakanyanya mudumbu asidi Iwe nachiremba wako munogona kukurukura nezvengozi dzingangoitika uye kuona kuti H2 receptor blockers ndiyo sarudzo yakanakisa yemamiriro ako chaiwo. Iwe haufanire kumbomira kutora mushonga wako usina kutaura nachiremba wako nezvazvo kutanga.

H2 Receptor Blockers vs. Proton Pump Inhibitors (PPIs)

Proton pump inhibitors (PPIs) ndeimwe mhando yemishonga inoshandiswa kudzikisa mudumbu acid uye kurapa acid Reflux kana GERD. Mienzaniso yePPIs inosanganisira esomeprazole (Nexium) uye pantoprazole (Protonix).

Ose ari maviri mishonga anoshanda nekudzivirira uye kudzikisa kugadzirwa kwemudumbu acid, asi maPPI anoonekwa seakasimba uye nekukurumidza mukuderedza dumbu acids. Nekudaro, H2 receptor blockers inonyatso kudzikisa iyo acid yakaburitswa manheru, inova inowanzo kupa kune peptic ulcers. Ichi ndicho chikonzero H2 receptor blockers inonyatsonyorerwa vanhu vane maronda kana vari panjodzi yekuiwana. PPIs inowanzo kuve yakatemwa kune vanhu vane GERD kana acid Reflux.

Vanachiremba kazhinji havakurudziri kutora zvese zviri zviviri PPI uye H2 receptor blocker panguva imwe chete. H2 receptor blockers inogona kukanganisa kushanda kwePPIs. Kana zviratidzo zvako zveGERD zvikasavandudzika nekushandiswa kwePPI, chiremba wako anogona kukurudzira H2 receptor blocker pachinzvimbo.

Mamwe marapirwo

Kana iwe uine maronda epeptic kana GERD, chiremba wako angangokurudzira kuti iwe usatore kutora mimwe mishonga uye kuti iwe uite mamwe mararamire shanduko kugadzirisa zviratidzo zvako.

Kana iwe uine maronda epeptic, chiremba wako anogona kukurudzira kuti iwe gadzirisa kushandisa kwako nonsteroidal anti-inflammatory drug (NSAIDs), senge aspirin uye ibuprofen. Kakawanda uye kwenguva refu kushandiswa kwemhando idzi dzemishonga kunogona kuwedzera njodzi yako yechironda chirwere. Chiremba wako anogona kukurudzira kuti utore acetaminophen panzvimbo. Nekudaro, haufanire kumira kutora chero mishonga usati wataura nachiremba wako kutanga.

Kugadzira mamwe maratidziro ehupenyu kunogona zvakare kubatsira kudzikisa peptic ulcer zviratidzo. Izvi zvinosanganisira:

  • kudzikisira kunwa doro
  • kudzivisa chikafu chinonaka
  • kuderedza kushushikana
  • kusvuta kusvuta

Kana iwe uine GERD kana acid Reflux, marongero ehupenyu ayo anogona kurerutsa zviratidzo anosanganisira:

  • kudya mashoma mashoma pazuva pazuva pane matatu makuru
  • kudzivirira doro, fodya, uye chikafu uye zvinwiwa zvinozivikanwa kukonzera zviratidzo
  • kusimudza musoro wemubhedha anenge matanhatu inches
  • kupedza mashoma mafuta
  • kudzivirira kurara pasi kweanenge maawa maviri mushure mekudya
  • kudzivisa tudyo tisati tarara

Taura nachiremba wako kana zviratidzo zvako zvisingavandudzike nemushonga kana mishonga yekurarama. Iwe ungangoda kurapwa kwakanyanya kana kuvhiyiwa kuti ubvise ulcer kana kuderedza acid Reflux.

Iwe unofanirwa kutsvaga kurapwa nekukurumidza kana chimwe chezviratidzo zvinotevera chikaitika:

  • unokudziridza kurwadziwa kwemudumbu kwakanyanya kushata kupfuura zvawakajaira kusangana nazvo
  • unotanga kupisa muviri zvakanyanya
  • unosangana nekurutsa izvo zvisiri nyore kurerukirwa
  • unovandudza dzungu uye musoro wakareruka

Izvi zviratidzo zvekushushikana kubva kune peptic ulcer chirwere chinoda kugadziriswa nekukasira.

Mubvunzo:

Pane chero munhu asingafanire kutora H2 receptor blockers?

Asingazivikanwe murwere

A:

Varwere chete vane zvakanyanya kana kutyisidzira hupenyu maitiro kuH2 blockers ndivo vanofanirwa kudzivirira kuvatora. Iyi kirasi yemishonga iri chikamu B mukuzvitakura zvinoreva kuti zvakachengeteka kutora panguva yekuzvitakura.

Tyler Walker, MDAmhinduro dzinomiririra iwo maonero evanyanzvi vezvokurapa. Zvese zvirimo ndezvechokwadi zvine ruzivo uye hazvifanire kutorwa sezano rekurapa.

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