Bartter chirwere

Bartter syndrome iboka remamiriro asingawanzo anokanganisa itsvo.

Kune mashanu majini kuremara kunozivikanwa kuve nekubatana neBartter syndrome. Mamiriro acho aripo pakuzvarwa (kuberekwa).

Mamiriro acho anokonzerwa nehurema muitsvo 'kugona kudzoreredza sodium. Vanhu vanokanganiswa neBartter syndrome vanorasikirwa nesodhoma yakawandisa kuburikidza neweti. Izvi zvinokonzera kukwira padanho rehormone aldosterone, uye zvinoita kuti itsvo dzibvise potassium yakawandisa kubva mumuviri. Izvi zvinozivikanwa sekuparadzwa kwepotassium.

Mamiriro acho zvakare anokonzeresa kusaenzana kweasidhi muyero muropa inonzi hypokalemic alkalosis, inokonzeresa calcium yakawandisa mumurini.

Ichi chirwere chinowanzoitika muhudiki. Zviratidzo zvinosanganisira:

• Kuzvimbirwa
• Chiyero chekuwedzera uremu chakadzikira zvakanyanya kupfuura icho chevamwe vana vezera rakaenzana uye bonde (kukura kutadza)
• Kutoda kuita weti kakawanda kupfuura zvakajairwa (urinary frequency)
• Kuderera kweropa
• Itsvo matombo
• Tsvina inopwanya uye kushaya simba

Bartter syndrome inowanzo fungidzirwa kana kuongororwa kweropa kukawana potasiamu shoma muropa. Kusiyana nedzimwe mhando dzehosha yeitsvo, mamiriro aya haakonzere BP. Iko kune tendero kune yakaderera BP. Rabhoritari bvunzo dzinogona kuratidza:

• Yakakwira mazinga e potassium, calcium, uye kloride mune weti
• Yakakwira mazinga emahormone, renin uye aldosterone, muropa
• Yakaderera ropa chloride
• Metabolic alkalosis

Izvi zviratidzo nezviratidzo zvinogona zvakare kuitika kune vanhu vanotora akawanda diuretics (mapiritsi emvura) kana laxatives. Weti miedzo inogona kuitwa kutonga zvimwe zvikonzero.

Iyo ultrasound yeitsvo inogona kuitwa.

Bartter syndrome inorapwa nekudya chikafu chakazara mu potassium kana kutora potasiamu zvinowedzera.

Vanhu vazhinji vanodawo munyu uye magnesium zvinowedzera.Mushonga unogona kudikanwa unovhara kugona kweitsvo kubvisa potasium. Yakakwira madosi ezve nonsteroidal anti-anogumbura zvinodhaka (NSAIDs) anogona zvakare kushandiswa.

Vacheche vane kukura kwakakomba kutadza vanogona kukura zvakajairika nekurapwa. Nokufamba kwenguva, vamwe vanhu vane chirwere vanozoita kukundikana kweitsvo.

Fonera wako mupi wezvehutano kana mwana wako ari:

• Kuva nemhasuru
• Kwete kukura zvakanaka
• Weti kakawanda

Kuparara kwe potassium; Munyu-kuputsa nephropathy

• Aldosterone level chiyero

Dixon BP. Yakagara nhaka tubular kutakura zvisina kujairika: Bartter syndrome. Mune: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chitsiko 549.1

Guay-Woodford LM. Hereditary nephropathies uye kukura kwakasarudzika kweiyo weti turakiti. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chits. 119.

Gomo DB. Kukanganisika kweiyo potasiamu chiyero. Mune: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. Brenner uye Rector Iyo Itsvo. 11th ed. Philadelphia, PA: Elsevier; 2020: chits. 17.