Chii chinonzi Hyperparathyroidism uye maitiro ekurapa

Zvemukati

• Zviratidzo zvikuru
• Maitiro ekuongorora
• Kurapwa kunoitwa sei

Hyperparathyroidism chirwere chinokonzera kuwanda kwehomoni PTH, yakaburitswa nezvirwere zveparathyroid, zviri mumutsipa kuseri kwetachiona.

Iyo hormone PTH inobatsira kuchengetedza huwandu hwecalcium muropa uye, kune izvo, ayo makuru mhedzisiro anosanganisira kudzoreredzwa kwecalcium muitsvo, kuwedzerwa kwakanyanya kwecalcium kubva kuchikafu mumatumbo, pamwe nekubvisa calcium yakachengetwa mumapfupa. kusunungura muropa.

Hyperparathyroidism inogona kumuka nenzira nhatu:

• Chikuru hyperparathyroidism: zvinoitika apo chirwere cheparathyroids pachacho chinokonzera hypersecretion yehomoni PTH, kunyanya nekuda kweadenoma kana hyperplasia yeaya maronda;
• Sekondari hyperparathyroidism: inomuka nekuda kwekukanganisa mumetabolism yemuviri, iyo inomutsa maseru eparathyroid, kunyanya nekuda kwekukundikana kwetsvo, uye izvo zvinokonzeresa huwandu hwecalcium uye phosphorus mukutenderera;
• Yepamusoro hyperparathyroidism: inonyanya kushomeka, inozivikanwa kana maronda eparathyroid anotanga kuburitsa yakawanda PTH pachavo, uye anogona kuoneka mushure menguva yechipiri hyperparathyroidism, semuenzaniso.

Kana ichinge yazivikanwa, hyperparathyroidism inoda kurapwa nekukasira, sezvo ichigona kuve nemhedzisiro, sekuderedza mapfupa, kuwedzera njodzi yekutyoka. Uye zvakare, yakawandisa calcium muropa inogona zvakare kukonzera shanduko mukushanda kwemhasuru, itsvo matombo, kuwedzerwa kweropa uye mamwe matambudziko emwoyo.

Ichi chirwere chinorapika kana kuvhiya kwaitwa kubvisa gland, zvisinei, zvisati zvaitika, mishonga inogona kuratidzwa iyo inogona kushandiswa kudzora zviratidzo.

Zviratidzo zvikuru

Zvimwe zvezviratidzo zvakajairika uye zviratidzo mune hyperparathyroidism ndeaya:

• Fragile bone uye ine njodzi yakakura yekutyoka;
• Tsvina kushaya simba;
• Kugadzirwa kweitsvo mabwe;
• Kuwedzera kukurudzira kuita weti;
• Kugara uchirwadziwa mudumbu;
• Kuneta zvakanyanya;
• Kuvandudzwa kweitsvo kutadza kana kurwara nepancreatitis;
• Nausea, kurutsa uye kurasikirwa nechido.

Hyperparathyroidism haigare ichikonzera zviratidzo, kunyanya mumatanho ekutanga, saka zvakajairika kuti chirwere ichi chizivikanwe mukuyera kuongororwa kweropa, izvo zvinoratidza shanduko muropa recalcium.

Maitiro ekuongorora

Kuongororwa kwe hyperparathyroidism kunoitwa pamwe nekuyerwa kwehomoni PTH, iyo inowedzerwa mumarudzi ese echirwere. Zvino, iyo endocrinologist ichaodha zvimwe bvunzo zvinobatsira kuziva chinokonzera dambudziko, senge calcium muyero, iyo yakakwira mune yekutanga hyperparathyroidism uye yakadzikiswa mune yechipiri, kuwedzera kune bvunzo dzakadai secalcium uye phosphorus mumurini, semuenzaniso.

Radiographic bvunzo dzinogona kubatsirawo kuziva chirwere, sezvo zvichiratidza mapfupa ane demineralization uye osteoporosis. Muzviitiko zvemberi, bvunzo iyi inogona kuratidza kuumbwa kwekuchera uye kuwanda kwemasukisi nemidziyo mumapfupa, ayo anozivikanwa se "bhuru bhuru".

Uye zvakare, bvunzo dzemufananidzo wedunhu remutsipa, ine ultrasound, scintigraphy kana imagineti resonance imaging, semuenzaniso, inogona kubatsira kuona shanduko mumatunduru eparathyroid.

Kurapwa kunoitwa sei

Nhanho yekutanga yekurapa kwekutanga hyperparathyroidism ndiko kugadzirisa kwecalcium mazinga, ayo, kana akashandurwa zvakanyanya, anogona kuve chikonzero chikuru chezviratidzo. Kune izvi, kune dzimwe sarudzo dzakasiyana, dzinosanganisira kutsiva kwehomoni, yakaitwa kunyanya muvakadzi mushure mekuguma kuenda kumwedzi, sekutsiva kwemamwe mahormoni kunobatsira kuchengetedza huwandu hwecalcium mumapfupa. Bisphosphonate zvinodhaka, kune rumwe rutivi, zvinobatsirawo kuwedzera kuiswa kwe calcium mumapfupa, ichideredza yemahara calcium muropa. Tarisa uone zvimwe zvinokonzeresa calcium muropa uye maitiro ekurapa.

Kuvhiya kunogona zvakare kuratidzwa mune yekutanga hyperparathyroidism, sezvo ichibvisa zvakakanganiswa gland, ichirapa chirwere. Nekudaro, ine dzimwe njodzi dzakadai sekukuvara kwetsinga dzinodzora tambo dzenzwi kana kuderera kwakacherechedzwa muzvikamu zvecalcium.

Panyaya yechipiri hyperparathyroidism, zvakafanira kuita chaiyo yekutarisa uye kurapwa kweitsvo kutadza, kutsiva kwemavhitamini D uye calcium, ayo akaderedzwa. Mishonga yecalcimimetic ine mhedzisiro yakafanana necalcium, zvichikonzera kuti gland ribudise mahormone mashoma. Muenzaniso wemishonga iyi ndeye cinacalcete.