Kunzwisisa Kurapa Kwekurapa kweMultiple Sclerosis

Zvemukati

• Q & A: Kugadzirisa kurapwa kweiyo infusion
• Mubvunzo:
• A:
• Kuiswa mushonga kurapwa
• Alemtuzumab (Lemtrada)
• Natalizumab (Tysabri)
• Mitoxantrone hydrochloride
• Ocrelizumab (Ocrevus)
• Zvimwe zvinokanganisa zveiyo infusion maitiro
• Zvimwe zvinokanganisa zveiyo infusion zvinodhaka
• Alemtuzumab
• Natalizumab
• Mitoxantrone hydrochloride
• Ocrelizumab
• Taura nachiremba wako

Kurapa multiple sclerosis (MS)

Multiple sclerosis (MS) chirwere chemuviri chinokanganisa iyo yepakati tsinga system (CNS).

NeMS, immune immune yako inokanganisa kurwisa tsinga dzako uye nekuparadza myelin, yavo yekudzivirira yekupfeka. Kana ikasarapwa, MS inogona kupedzisira yaparadza iyo yese myelin yakakomberedza tsinga dzako. Ipapo zvinogona kutanga kukuvadza tsinga pachadzo.

Iko hakuna mushonga weMS, asi kune akati wandei marudzi ekurapa. Mune zvimwe zviitiko, kurapwa kunogona kunonoka kumhanya kweMS. Kurapa kunogona kubatsira kudzikamisa zviratidzo uye kudzikisira kukanganisa kunogona kuitwa neMS flare-ups. Flare-ups inguva iyo iwe paunenge uine zviratidzo.

Nekudaro, kana kurwisa kwatanga, ungangoda imwe mhando yemishonga inonzi chirwere chinogadzirisa. Zvirwere zvinoshandura zvinogona kuchinja maitiro echirwere. Ivo vanogona zvakare kubatsira kunonoka kufambira mberi kweMS uye kudzikisira mafere-ups.

Zvimwe zvekurapa-zvinoshandura marapirwo zvinouya sekupinza mishonga. Aya ekurapa ekumisikidza anogona kunyanya kubatsira kune vanhu vane hutsinye kana hwemberi MS. Verenga pamusoro kuti udzidze zvakawanda nezve iyi mishonga uye nemabatiro avanobatsira kubata MS.

Q & A: Kugadzirisa kurapwa kweiyo infusion

Mubvunzo:

Kurapa kwekumukirwa kunopihwa sei?

Asingazivikanwe murwere

A:

Iyi mishonga inobayiwa jekiseni. Izvi zvinoreva kuti unovagamuchira kuburikidza netsinga yako. Zvisinei, iwe hausi jekiseni mishonga iyi iwe pachako. Iwe unogona chete kugamuchira mishonga iyi kubva kune wehutano mupi mune yehutano nzvimbo.

Iyo Healthline Medical TeamMhinduro dzinomiririra iwo mafungiro evanachiremba vedu vezvekurapa. Zvese zvirimo ndezvechokwadi zvine ruzivo uye hazvifanire kutorwa sezano rekurapa.

Kuiswa mushonga kurapwa

Nhasi kune mana asingabatike madhiragi aripo ekurapa MS.

Alemtuzumab (Lemtrada)

Vanachiremba vanopa alemtuzumab (Lemtrada) kuvanhu vasina kupindura zvakanaka kune angangoita maviri mamwe maMS mishonga.

Mushonga uyu unoshanda nekuderedza zvishoma nezvishoma nhamba yemuviri wako yeT uye B maLymphocyte, ayo ari marudzi emaseru machena eropa (WBCs). Ichi chiito chinogona kudzora kuzvimba uye kukuvara kwemaseru etsinga.

Iwe unogashira uyu mushonga kamwe pazuva pazuva kwemazuva mashanu. Zvino gore rimwe mushure mekurapwa kwako kwekutanga, unogashira mushonga kamwe pazuva pazuva kwemazuva matatu.

Natalizumab (Tysabri)

Natalizumab (Tysabri) inoshanda nekumisa maseru ekudzivirira ekukuvadza kuti apinde muuropi uye musana. Iwe unogamuchira ichi chinwiwa kamwe chete pavhiki ina.

Mitoxantrone hydrochloride

Mitoxantrone hydrochloride ndeye MS infusion kurapwa pamwe nechemotherapy mushonga unoshandiswa kurapa cancer.

Inogona kushanda zvakanyanya kune vanhu vane sekondari inofambira mberi MS (SPMS) kana kukurumidza kuwedzera MS. Imhaka yekuti imunosuppressant, zvinoreva kuti inoshanda kumisa immune system yako kuita kweMS kurwisa. Izvi zvinogona kudzikisa zviratidzo zveMS flare-up.

Iwe unogamuchira ichi chinwiwa kamwe chete pamwedzi mitatu yehupenyu hwakawanda huwandu hwekuwedzera (140 mg / m²) izvo zvinogona kusvika mukati memakore maviri kusvika matatu. Nekuda kwenjodzi yemhedzisiro, zvinongokurudzirwa kune vanhu vane MS yakaoma.

Ocrelizumab (Ocrevus)

Ocrelizumab ndiyo nyowani nyowani yekurapa kweMS. Yakagamuchirwa neKudya neDrug Administration (FDA) muna2017.

Ocrelizumab inoshandiswa kurapa kudzokazve kana mafomu ekutanga eMS. Muchokwadi, ndiwo mushonga wekutanga unobvumidzwa kurapa yekutanga inofambira mberi MS (PPMS).

Mushonga uyu unofungidzirwa kuti unoshanda nekutarisa maBymphocyte ayo anokonzeresa kukuvara kwemyelin sheath nekugadzirisa.

Inotanga kupihwa mumazana maviri emamirigiramu infusions, akapatsanurwa nemavhiki maviri. Mushure meizvozvo, inopihwa mazana matanhatu emamirigiramu infusions mwedzi mitanhatu yega yega.

Zvimwe zvinokanganisa zveiyo infusion maitiro

Iyo yekumisikidza maitiro pachayo inogona kukonzeresa mhedzisiro, iyo inogona kusanganisira:

• kupwanya kana kubuda ropa panzvimbo yejojo
• kutsvaira, kana kutsvuka uye kudziya kweganda rako
• chills
• kusvotwa

Iwe unogona zvakare kuve neiyo infusion reaction. Uku ndiko kuita kwezvinodhaka paganda rako.

Kune ese aya madhiragi, kupindirwa kwekumanikidza kunowanzoitika mukati maawa maviri ekutanga ehutongi, asi mhinduro inogona kuitika kusvika maawa makumi maviri nemana gare gare. Zviratidzo zvinogona kusanganisira:

• mikoko
• mavara ane ganda rako
• kudziya kana kupisa muviri
• mapundu

Zvimwe zvinokanganisa zveiyo infusion zvinodhaka

Chimwe nechimwe chinodhaka chinodhaka chine mhedzisiro yadzo.

Alemtuzumab

Iyo yakajairika mhedzisiro mhedzisiro yechirwere ichi inogona kusanganisira:

• mapundu
• musoro
• kupindwa nechando
• dzihwa
• kusvotwa
• Urinary turakiti hutachiona (UTI)
• kuneta

Mushonga uyu unogona zvakare kukonzera zvakakomba, uye zvinogona kuuraya, mhedzisiro. Zvinogona kusanganisira:

• autoimmune reaction, senge Guillain-Barré syndrome uye nhengo kutadza
• gomarara
• kusagadzikana kweropa

Natalizumab

Iyo yakajairika mhedzisiro mhedzisiro yechirwere ichi inogona kusanganisira:

• zvirwere
• neutachiona
• musoro
• kuneta
• kuora mwoyo

Matambudziko akakomba anogona kusanganisira:

• hutachiona husingawanzo uye hunouraya hutachiona hunonzi progressive multifocal leukoencephalopathy (PML)
• matambudziko echiropa, ane zviratidzo zvakadai se:
  • kuita yero kweganda rako kana kuchena kwemaziso ako
  • yakasviba kana shava (yeti-yeruvara) weti
  • kurwadziwa kumusoro kwekurudyi kwedumbu rako
  • kubuda ropa kana kupwanya kunoitika zviri nyore kupfuura zvakajairwa
  • kuneta

Mitoxantrone hydrochloride

Iyo yakajairika mhedzisiro mhedzisiro yechirwere ichi inogona kusanganisira:

• yakaderera WBC mazinga, ayo anogona kuwedzera mukana wako wehutachiona
• kuora mwoyo
• kurwadziwa kwepfupa
• kusvotwa kana kurutsa
• kurasikirwa nevhudzi
• UTI
• amenorrhea, kana kushomeka kwemwedzi

Matambudziko akakomba anogona kusanganisira:

• congestive moyo kutadza (CHF)
• itsvo kutadza

Kugamuchira zvakawandisa zvemushonga uyu kunokuisa panjodzi yemhedzisiro inogona kutyisa muviri wako, saka mitoxantrone inofanira kungoshandiswa mumatambudziko akasimba eMMS. Izvi zvinosanganisira CHF, kukundikana kweitsvo, kana nyaya dzeropa. Chiremba wako anokucherekedza zvakanyanya padhuze nezviratidzo zvemhedzisiro panguva yekurapwa nemushonga uyu.

Ocrelizumab

Iyo yakajairika mhedzisiro mhedzisiro yechirwere ichi inogona kusanganisira:

• zvirwere
• infusion maitiro

Matambudziko akakomba anogona kusanganisira:

• PML
• kugadzirisazve hepatitis B kana shingles, kana vatove muhurongwa hwako
• immune system isina kusimba
• gomarara, kusanganisira gomarara repazamu

MIMWE MISANGANO YOKUSVIRA

Mune zvimwe zviitiko, chiremba wako anogona kukurudzira kumwe kurapa kwekunyudzwa. Aya marapirwo anogona kushandiswa kurapa kudzoka kusingapindure kune corticosteroids. Zvinosanganisira plasmapheresis, iyo inosanganisira kubvisa ropa kubva mumuviri wako, kurisefa kubvisa ma antibodies anogona kunge ari kurwisa system yako yetsinga, uye kutumira iro "rakacheneswa" ropa zvakare mumuviri wako kuburikidza nekuisirwa. Izvo zvinosanganisirawo intravenous immunoglobulin (IVIG), jekiseni rinobatsira kuwedzera immune system yako.

Taura nachiremba wako

Kurapa kwekumisikidza inogona kuve yakanaka sarudzo yekubatsira kubata zviratidzo zveMS uye kuputika. Zvisinei, mishonga iyi haina kukodzera munhu wese. Ivo vanotakura njodzi dzeasingawanzo asi zvakakomba matambudziko. Zvakadaro, vanhu vazhinji vakavaona vachibatsira.

Kana iwe uine MS inofambira mberi kana uri kutsvaga nzira iri nani yekugadzirisa zviratidzo zvako, bvunza chiremba wako nezve infusion kurapwa. Ivo vanogona kukubatsira iwe kusarudza kana iyi mishonga ingave iri sarudzo yakanaka kwauri.