Zvese Zvaunoda Kuti Uzive Nezve Johnson & Johnson's COVID-19 Vaccine

Zvemukati

• Mushonga weJohnson & Johnson COVID-19 unoshanda sei?
• Mushonga weJohnson & Johnson COVID-19 unoshanda zvakadii?
• Yakanyanya COVID-19 Kurwara uye Rufu Data
• COVID-19 Variants
• Mangani madhizaizi ejekiseni raJohnson & Johnson COVID-19 raunoda?
• Ko jekiseni raJohnson & Johnson rinokanganisa sei kutapurirana kweCCIDID-19?
• Ongororo ye

Musi waFebruary 26, iyo FDA's vaccine yekuzvidzivirira komiti yakabvumirana kuti Johnson & Johnson's COVID-19 mushonga wekushandisa zvechimbichimbi. Izvi zvinoreva kuti jekiseni - iro rinoda imwe chete - rinogona kunge rakagadzirira kushandiswa muU.S. pakupera kwaKurume, sekureva kweCentre for Infectious Disease Research and Policy (CIDRAP).

Asi, mushonga weJohnson & Johnson weCCVID-19 unoshanda zvakadii? Uye inofananidzwa sei nemamwe majekiseni eCOVID-19 kubva kuPfizer neModerna? Hezvino izvo zvaunoda kuziva.

Mushonga weJohnson & Johnson COVID-19 unoshanda sei?

Kana iwe uchiziva nemishonga yekudzivirira yeCOVID-19 yakagadzirwa naPfizer neModerna, saka ungangoziva kuti ese ari maviri majekiseni emRNA. Izvi zvinoreva kuti vanoshanda nekukodha chikamu cheSARS-CoV-2 virus's spike protein (chikamu chehutachiona chinozvinamatira kumaseru ari mumuviri wako) uye nekushandisa iwo encoded zvidimbu kukonzeresa mhinduro kubva mumuviri wako kuti igadzire. masoja ekudzivirira chirwere. (Ona: Inoshanda Sei Iyo COVID-19 Vaccine?)

Mushonga weJohnson & Johnson unoshanda zvishoma zvakasiyana. Kune chimwe chinhu, haisi mRNA yekudzivirira. Mushonga weadenovector, zvinoreva kuti inoshandisa hutachiona husingaite (mune iyi kesi, adenovirus, iyo inokonzera kutonhora kwakazara) sevheji kuburitsa mapuroteni (mune ino kesi, iyo spike protein kubva kuSARS-CoV-2) iyo muviri wako vanoona sekutyisidzira uye kugadzira maantibhakitiriya anorwisa, anodaro Brittany Busse, MD, mubatanidzi director wezvekurapa kuWorkCare.

Zvino, unogona kunge uchishamisika kana kuisa "inactivated virus" mumuviri wako kuchizoita kuti urware usingazivi, asi hazvigone. "Hutachiona husina kuvharwa hahugone kupeta kana kuita kuti urware," anodaro Abisola Olulade, MD, chiremba ane hunyanzvi hwekurapa mhuri kuSharp Rees-Stealy Medical Group. Asi, iyo adenovirus muJohnson & Johnson's COVID-19 yekudzivirira inongoshanda semutakuri (kana "vector") weSARS-CoV-2's spike protein gene mumaseru ako, zvichiita kuti maseru aite makopi ejini irori, anotsanangura. Funga nezve iyo spike protein geni seti yemirairo yekuti muviri wako ungarwisa sei SARS-CoV-2, anowedzera Dr. Olulade. "Aya mapuroteni epiki anogona kucherechedzwa nema immune system ako uye anoita kuti iwe ugadzire masoja ekudzivirira anodzivirira ku COVID," anotsanangura. (FYI: Kupfurwa kwefuruwenza kunoshanda nenzira yakafanana.)

Nepo hunyanzvi hwejekiseni hwakasiyana nehwaPfizer neModerna, haisi pfungwa yekufungidzira. Oxford neAstraZeneca's COVID yekudzivirira - iyo yakatenderwa kushandiswa muEU neUK muna Ndira (iyo FDA parizvino yakamirira pane data kubva kuAstraZeneca's kiriniki kuyedzwa isati yafunga mvumo yeUS, iyo New York Times inoshuma) - inoshandisa yakafanana adenovirus tekinoroji. Johnson & Johnson vashandisawo tekinoroji kugadzira mushonga wavo weEbola, uyo wakaratidzirwa kuve wakachengeteka uye unoshanda mukugadzira immune immune mumuviri.

Mushonga weJohnson & Johnson COVID-19 unoshanda zvakadii?

Mukiriniki yakakura yekuyedza kweanoda kusvika vanhu zviuru makumi mana nezvina, mushonga weJohnson & Johnson weCOVID-19 wakaratidzirwa kuve 66 muzana inoshanda zvakakwana mukudzivirira zvine mwero (zvinotsanangurwa sekuva nechiratidzo chimwe chete kana kupfuura zveCOVID-19) kune chakakomba COVID-19 (inozivikanwa ne kubvumirwa kuICU, kutadza kufema, kana kutadza kwenhengo, pakati pezvimwe zvinhu) mazuva makumi maviri nemasere mushure mekudzivirira, maererano nekuburitswa kwenhau kubva kukambani. (Iyo data "ichaendeswa kupepanhau rinoongororwa nevezera mumavhiki anouya," inodaro kuburitswa kwenhau.)

Johnson & Johnson vakagovanawo kuti nhanho yekudzivirira yekudzivirira kubva pakati kusvika kune yakanyanya COVID yaive makumi manomwe neshanu muzana muUS, makumi matanhatu nenhanhatu muzana muLatin America, uye makumi mashanu nenomwe muzana muSouth Africa (iyo, yakaenzana pamwe chete, inokupa iyo yakazara makumi matanhatu nenhanhatu muzana) . Kana nhamba idzodzo dzichiita sedzinoremesa, zvakakosha kuti ticherechedze kuti, kana tichienzanisa, furuwenza inongori makumi mana kusvika makumi matanhatu muzana muzana mukudzivirira muviri kubva mufuruu, asi ichiri kuita basa guru mukuderedza zvipatara zvine chekuita nefuruwenza nerufu, anodaro. Dr. Olulade. (Yakabatana: Iyo Flu Shot Inokudzivirira Iwe kubva kuCoronavirus?)

Yakanyanya COVID-19 Kurwara uye Rufu Data

Pakutanga, jekiseni rekudzivirira mushonga raJohnson & Johnson re66 muzana rinogona kuita serakaderera, kunyanya kana iwe uchienzanisa nemitengo yekubudirira kubva Moderna (94.5 muzana inoshanda) uye Pfizer ("inopfuura 90 muzana inoshanda," sekureva kwekambani). Asi kana iwe ukachera zvakadzika, data yaJohnson & Johnson ita ratidza zvimwe zvinovimbisa mhedzisiro, kunyanya kana zvasvika kune dzakaipisisa nyaya dzeCOVID-19.

Pakati pematunhu ese, mushonga wacho waive 85 muzana inoshanda mukudzivirira kwakasimba COVID-19, sekureva kwekuburitswa kwaJohnson & Johnson. Muchokwadi, kambani yakacherekedza kuti jekiseni rayo rakaratidza "kudzivirirwa kwakakwana kubva kuchipatara chakabatana neCOVID uye kufa" mazuva makumi maviri nemasere mushure mekubaiwa, "pasina nyaya dzakataurwa" dzekuchengetwa kwakabatana neCOPVID kana kufa pakati peavo vakagamuchira mushonga waJohnson & Johnson.

Panyaya yemhedzisiro, Johnson & Johnson vakati vaccine yavo yeCOVID "yakatenderwa" kune vese vatori vechikamu muyedzo. Dhiyabhorosi yekambani data inoratidza kuti jekiseni rinogona kukonzera "zvinyoro-kusvika-zvine mwero mhedzisiro zvinowanzobatanidzwa nekubaiwa," kusanganisira kuneta, kutemwa nemusoro, kusuruvara kwemhasuru, uye kurwadziwa kwenzvimbo yejekiseni.

COVID-19 Variants

Kusiyana nezvidzidzo zvePfizer uye zveModerna, kuyedza kwekudzivirira kwaJohnson & Johnson kunosanganisira mhedzisiro munzvimbo dzakawanda - kusanganisira idzo dzakangoona kukwira kweCCIDID kesi zvakakonzerwa nemhando dzakasiyana dzehutachiona. "[Iyi misiyano] inogona kunge isina kuve yakakosha panguva iyo majekiseni apfuura aiongororwa," anodaro Dr. Olulade. Zvechokwadi, vatsvakurudzi vave kutarisa kuti inoshanda sei zvese COVID-19 majekiseni anogona kunge ari mukudzivirira muviri kubva akasiyana COVID-19 akasiyana. Parizvino, Dr. Busse vanoti musiyano weUK "haungatarise majekiseni eCOVID." Zvisinei, anowedzera, ipapo ndizvo kufungidzira kuti ma COVID akasiyana kubva kuSouth Africa neBrazil anogona "kushandura nzira marwidzi anopindirana nehutachiona" uye zvinogona kuita kuti masoja ekudzivirira aya "asanyanya kushanda." (Inoenderana: Nei Nyowani COVID-19 Materu Ari Kupararira nekukurumidza?)

Izvo zvakati, nepo jekiseni risingakwanise kudzivirira hutachiona hwe COVID-19 zvachose, zvinoita sekubatsira vanhu kudzivirira hutachiona hwakaipisisa. "Izvi zvinoreva zvakare kuti ine mukana wekudzora mutoro pane yedu yakaremerwa system yehutano uye inotiswededza padyo nechiedza icho pakupera kwemugero," anodaro Dr. Olulade.

"Zvakakoshawo kuyeuka kuti nekukurumidza kwatinoita kuti vanhu vabaye nhomba, shanduko shoma hutachiona hunofanirwa kuchinja uye kuita," anowedzera Dr. Olulade. "Ndosaka tichifanira kutora munhu wese [kubayiwa majekiseni] nekukurumidza."

Mangani madhizaizi ejekiseni raJohnson & Johnson COVID-19 raunoda?

Kunze kwekushanda kwemushonga wacho pachawo, nyanzvi dzinoti jekiseni raJohnson & Johnson reCOVID riri kuvimbisawo nekuti rinongoda pfuti imwe chete, nepo majekiseni ePfizer naModerna rimwe nerimwe richida kupfura kaviri kwakaparadzaniswa nevhiki dzinoverengeka.

"Izvi zvinogona kunyatso chinja mutambo," anodaro Dr. Olulade. "Isu tinoona kuti vamwe varwere, zvinosuwisa, havadzokere kune yavo yechipiri dosi," saka iyi nzira-uye-yakaitwa nzira inogona kududzira kune mamwe majekiseni akazara.

Imwe huru yekushandisa kune Johnson & Johnson's COVID jekiseni? Maitiro acho zviri nyore nzira yekuchengetera nekuparadzira kupfuura majekiseni ePfizer naModerna, nekuda kwekushandisa kwaJ & J kweiyo adenovector yekudzivirira tekinoroji. "Adenovirus [mujekiseni raJohnson & Johnson] yakachipa uye haina kusimba [sezvinoita mRNA muPfizer's uye Moderna's vaccines]," iyo yekupedzisira inoda kuchengetwa pakutonhora kwakanyanya, anotsanangura Dr. Busse. "Mushonga weJohnson & Johnson wakagadzikana mufiriji kwemwedzi inosvika mitatu, izvo zvinoita kuti zvive nyore kutumira uye kugovera kune vanoida."

Ko jekiseni raJohnson & Johnson rinokanganisa sei kutapurirana kweCCIDID-19?

"Kwangotanga kwazvo kutaura," anodaro Prabhjot Singh, MD, Ph.D., chipangamazano mukuru wezvekurapa nesainzi weCV19 CheckUp, chishandiso chepamhepo chinobatsira kuongorora njodzi dzako dzeCOVID-19. Izvo zvinoenda zvese yemajekiseni eCOVID-19 ataona kusvika pari zvino BTW, kwete Johnson & Johnson chete, anodaro Dr. Singh. "Ongororo dzekutanga dzinoratidza kuti njodzi yekutapurirana inofanira kudzikira mushure mekubaiwa jekiseni, asi mhinduro yakajeka inoda kudzidza kwakarongeka," anotsanangura kudaro.

Sezvo majekiseni 'maitiro pane kutapurirana kweECVID achiri kusazivikanwa, zvakanyanyisa kukosha kuramba uchipfeka mamask uye kuchengetedza chinhambwe chako kubva kune vanhu vari kunze kwemusha wako, anodaro Dr. Olulade. (Mira, iwe unofanirwa kuve uchivhara-miviri kudzivirira kubva kuCOVID-19?)

Pazasi mutsara: Zvese yeaya majekiseni anoita kunge anopa dziviriro yakakosha kubva ku COVID-19, inova yakanaka. Kunyange zvakadaro, “jekiseni rekudzivirira zvirwere harisi rezinesi rekurega munhu akangwarira,” anotsanangura kudaro Dr. Olulade. "Tinofanirwa kufunga zvisina hudyire nezvehutano uye hutano hwevamwe vasati vabaiwa uye vanogona kunge vasati vadzivirirwa kubva kuCOVID."

Mashoko ari munyaya iyi akarurama seye nguva yekudhinda. Sezvo zvigadziriso nezve coronavirus COVID-19 ichiramba ichichinja, zvinokwanisika kuti rumwe ruzivo uye kurudziro munyaya iyi zvachinja kubva pakatanga kuburitswa. Tinokukurudzira kuti uongorore nguva zhinji zviwanikwa zvakaita seCDC, iyo WHO, uye nedhipatimendi rako rezvehutano reveruzhinji kune yakanyanya-kudhara dhata uye kurudziro.

Ongororo ye