Myelodysplasia: chii icho, zviratidzo uye kurapwa
Zvemukati
Myelodysplastic Syndrome, kana myelodysplasia, inowirirana neboka rezvirwere zvinoratidzirwa nekufambira mberi kukundikana kwemongo wemapfupa, izvo zvinotungamira mukugadzirwa kwemasero akaremara kana asina kusimba ayo anoonekwa muropa, zvichikonzera kushomeka kweropa, kuneta zvakanyanya, kuda kutapukira uye kubuda ropa. kazhinji, izvo zvinogona kutungamira kumatambudziko akakomba.
Kunyangwe ichigona kuoneka pazera ripi zvaro, chirwere ichi chinowanzoitika muvanhu vanopfuura makore makumi manomwe ekuberekwa, uye kazhinji kacho, zvikonzero zvacho hazvisi kujekeswa, kunyangwe mune dzimwe nguva zvinogona kumuka semhedzisiro yekurapa kenza yapfuura nekemotherapy, radiation radiation kana kuratidzwa kumakemikari, senge benzene kana utsi, semuenzaniso.
Myelodysplasia inogona kupora nekuiswa kwemongo wemapfupa, zvisinei, izvi hazvigoneke kuvarwere vese, uye zvakakosha kutsvaga nhungamiro kubva kune mukuru wezvechiremba kana wehematologist.
Zviratidzo zvikuru
Bone marora inzvimbo yakakosha mumuviri inoburitsa masero eropa, akaita semasero matsvuku eropa, ayo ari masero matsvuku eropa, leukocyte, ayo ari machena masero eropa ane chekuita nekudzivirira muviri nemaplatelet, ayo akakosha mukugwamba kweropa. Naizvozvo, kukanganisika kwako kunounza zviratidzo nezviratidzo zvakaita se:
- Kuneta zvakanyanya;
- Pallor;
- Kufema kwekufema;
- Kuda kutapukirwa;
- Kupindwa nechando;
- Kubuda ropa;
- Chitarisiko chemavara matsvuku pamuviri.
Muzviitiko zvekutanga, munhu wacho anogona kusaratidza zviratidzo, uye chirwere chinopedzisira chave kuwanikwa mune bvunzo dzechiitiko. Uye zvakare, huwandu uye kusimba kwezviratidzo zvinoenderana nemhando dzeropa maseru anonyanya kukanganiswa nemyelodysplasia uye zvakare kuomarara kwenyaya imwe neimwe. Inenge 1/3 yezviitiko zveiyo myelodysplastic syndrome inogona kufambira mberi kusvika kuacute leukemia, iri mhando yekenza yakaoma yemasero eropa. Tarisa uone zvakawanda nezveacute myeloid leukemia.
Nekudaro, hazviite kuti utarise nguva yekutarisirwa kwehupenyu kwevarwere ava, sezvo chirwere ichi chichigona kushanduka zvishoma nezvishoma, kwemakumi emakore, sezvo chichigona kushanduka kuita fomu yakaoma, isina mhinduro shoma kurapa uye ichikonzera mamwe matambudziko mumwedzi mishoma. makore.
Ndezvipi zvikonzero
Chikonzero chemyelodysplastic syndrome hachina kunyatso simbiswa, zvisinei muzviitiko zvakawanda chirwere ichi chine hutachiona hunokonzera, asi shanduko muDNA haiwanzo kuwanikwa, uye chirwere chinoiswa seyakanyanya myelodysplasia. Kunyangwe chingave chakakonzera chibereko, chirwere hachina kugarwa nhaka.
Myelodysplastic syndrome inogona zvakare kuverengerwa sekondari painomuka semhedzisiro yemamwe mamiriro, senge kudhakwa kunokonzerwa nemakemikari, senge chemotherapy, radiotherapy, benzene, mishonga yekuuraya zvipuka, fodya, lead kana mercury, semuenzaniso.
Maitiro ekusimbisa
Kuti asimbise kuongororwa kwe myelodysplasia, iyo hematologist ichaita iyo yekiriniki kuongorora uye kurongedza bvunzo senge:
- Kuverenga kweropa, iyo inosarudza huwandu hwemasero matsvuku eropa, leukocyte uye maplatelet muropa;
- Myelogram, inova iyo aspirin yemongo wemapfupa inokwanisa kuongorora huwandu uye hunhu hwesero riri munzvimbo ino. Nzwisisa kuti myelogram inogadzirwa sei;
- Genetic uye immunological bvunzo, senge karyotype kana immunophenotyping;
- Bone marora bhiopsy, iyo inogona kupa rumwe ruzivo nezve zvemukati wemongo, kunyanya kana ichinge yashandurwa zvakanyanya kana ichitambura nemamwe matambudziko, akadai sefibrosis infiltrations;
- Chipimo chematare, vhitamini B12 uye folic acid, sezvo kushomeka kwavo kunogona kukonzera shanduko mukugadzirwa kweropa.
Nenzira iyi, iyo hematologist ichave ichikwanisa kuona mhando ye myelodysplasia, kusiyanisa kubva kune zvimwe zvirwere zvemongo wemapfupa uye zvirinani kuona mhando yekurapa.
Kurapwa kunoitwa sei
Iyo huru fomu yekurapa ndeyekupfekedza mwongo wemapfupa, izvo zvinogona kutungamira pakurapa kwechirwere, zvisinei, havazi vese vanhu vanokodzera maitiro aya, ayo anofanirwa kuitwa mune vanhu vasina zvirwere zvinodzora kugona kwavo kwemuviri uye zviri nani pasi makore makumi matanhatu nemashanu.
Imwe nzira yekurapa inosanganisira chemotherapy, iyo inowanzoitwa nemishonga yakaita seAzacitidine uye Decitabine, semuenzaniso, inoitwa mumatunhu akasarudzika nahematologist.
Kuwedzerwa ropa kunogona kudikanwa mune dzimwe nguva, kunyanya kana paine kushomeka kwakanyanya kana kushomeka kwemaplatelet anotendera kugwamba kweropa kwakaringana. Tarisa zvinoratidza uye kuti kuwedzerwa ropa kunoitwa sei.