Monocytes: zvavari uye mareferensi tsika

Zvemukati

• Yakakwirira monocytes
• Yakaderera monocytes
• Referensi tsika

Monocyte iboka remasero ezvirwere zvemuviri zvine basa rekudzivirira muviri kubva kumitumbi yekunze, sevirusi uye hutachiona. Vanogona kuverengwa kuburikidza nekuongororwa kweropa kunodaidzwa kuti leukogram kana kukwana kwakazara kweropa, izvo zvinounza huwandu hwemasero ekudzivirira mumuviri.

Monocyte inogadzirwa mumongo wemapfupa uye inotenderera kwemaawa mashoma mukutenderera, uye woenderera kune mamwe matishu, kwavanoitisa musiyano, vachigamuchira zita rekuti macrophage, iro rine mazita akasiyana maererano nechitunha mairi. Kupffer masero, muchiropa, microglia, mune yemagetsi system, uye maLangerhans maseru ari muepidermis.

Yakakwirira monocytes

Kuwedzera kwenhamba yemonocytes, inonziwo monocytosis, inowanzo kuratidza hutachiona husingaperi, senge tibhii, semuenzaniso. Uye zvakare, panogona kuve nekuwedzera kwehuwandu hwe monocytes nekuda kwe ulcerative colitis, protozoal hutachiona, chirwere che Hodgkin, myelomonocytic leukemia, multiple myeloma uye autoimmune hosha dzakadai se lupus uye rheumatoid arthritis.

Kuwedzera kwemonocytes hakuwanzo kukonzera zviratidzo, kuchionekwa chete kuburikidza nekuongororwa kweropa, iro rakazara huwandu hweropa. Nekudaro, panogona kuve nezviratidzo zvine chekuita nechikonzero che monocytosis, uye inofanirwa kuongororwa uye kurapwa maererano nezvakakurudzirwa nachiremba. Nzwisisa kuti chii chinonzi kuverenga ropa uye kuti ndechei.

Yakaderera monocytes

Kana monocyte kukosha kwadzikira, mamiriro anonzi monocytopenia, zvinowanzoreva kuti immune system inoshomeka, sezvazvinoita mukutapukirwa neropa, chemotherapy kurapwa uye matambudziko emongo wemapfupa, senge aplastic anemia uye leukemia. Uye zvakare, zviitiko zvehutachiona hweganda, kushandiswa kwecorticosteroids uye hutachiona hweHPV kunogona kukonzera kudzikira kwenhamba yemamonocytes.

Kuonekwa kwehunhu padyo ne0 emamonocytes muropa hakuwanzo uye, kana zvikaitika, zvinogona kureva kuvepo kweMonoMAC Syndrome, chinova chirwere chemajini chinoratidzwa nekushayikwa kwekugadzirwa kwemamonocytes nefupa remongo, iro zvinogona kukonzera hutachiona, kunyanya paganda. Muzviitiko izvi, kurapwa kunoitwa nemishonga yekurwisa hutachiona, senge maantibayoti, uye zvinogona zvakare kudikanwa kuti ugochinjisa mwongo wepfupa kuporesa chinetso chemajini.

Referensi tsika

Iwo mareferenzi hunhu hunosiyana zvichienderana nerabhoritari, asi inowanzoenderana ne2 kusvika ku10% yemareukocyte akazara kana ari pakati pe300 kusvika 900 monocyte pa mm³ yeropa.

Kazhinji, shanduko muhuwandu hwemaseru aya haukonzere zviratidzo mumurwere, uyo anongonzwa zviratidzo zvechirwere izvo zvinokonzeresa kuwedzera kana kuderera kwemamonocytes. Uye zvakare, mune dzimwe nguva murwere anongowana chete kuti pane imwe shanduko kana uchiita ongororo yeropa.