Cannabidiol oiri (CBD): zvazviri uye mabhenefiti angangoitika

Zvemukati

• Maitiro eCannabidiol Oiri Anoshanda
• Zvinogona kuitika kubatsirwa kwehutano
• Zvinogona kuitika mhedzisiro

Cannabidiol oiri, inozivikanwawo seCDD mafuta, chinhu chinowanikwa kubva kumuti Cannabis sativa, inozivikanwa sembanje, iyo inokwanisa kubvisa zviratidzo zvekushushikana, kubatsira pakurapa kushaya hope uye kuwana mabhenefiti pakurapa pfari.

Kusiyana nedzimwe mbanje-based zvinodhaka, cannabidiol oiri haina THC, chinova chinhu chembanje inoitisa psychotropic mhedzisiro, senge kurasikirwa kwekuziva uye kukanganisa mukati menguva nenzvimbo, semuenzaniso. Naizvozvo, cannabidiol oiri ingangodaro inoshandiswa mukiriniki tsika. Dzidza nezve zvimwe zvinokonzeresa mbanje.

Zvisinei, zvimwe zvidzidzo zvinodiwa kujekesa zvakanakira mafuta eCDD mudambudziko rega rega, pamwe neyakagadziriswa mushe.

Maitiro eCannabidiol Oiri Anoshanda

Iko kuita kwe cannabidiol oiri kunonyanya kukonzerwa nebasa rayo pane maviri maakagamuchirwa aripo mumuviri, anozivikanwa seCB1 uye CB2. CB1 inowanikwa muuropi uye inoenderana nemutemo wekuburitswa kweiyo neurotransmitter uye neuronal chiitiko, nepo CB2 irimo mune nhengo dzeLymphoid, inova inokonzeresa mhinduro dzinopisa uye dzinotapukira.

Nekuita pane CB1 receptor, cannabidiol inokwanisa kudzivirira zvakanyanya neuronal chiitiko, zvichibatsira kuzorora uye kudzikisa zviratidzo zvine chekuita nekushushikana, pamwe nekugadzirisa marwadzo kuona, ndangariro, kubatana uye kugona kugona. Kana uchiita pane inogamuchira CB2, cannabidiol inobatsira mukuburitsa cytokines nemaseru ezvirwere zvemuviri, izvo zvinobatsira kudzikisa kurwadziwa nekuzvimba.

Zvinogona kuitika kubatsirwa kwehutano

Nekuda kwemabatiro anoita oiri yeCBD mumuviri, kushandiswa kwayo kunogona kuunza mabhenefiti ehutano uye kunyangwe kutariswa pakurapa kwezvimwe zvirwere:

• Pfari: zvimwe zvidzidzo zvakaratidza kuti cannabidiol oiri inokwanisa kudzikamisa kuwanda kwekugwinha nekuda kwekudyidzana kwechinhu ichi ne CB1 mhando dzinogamuchira muuropi, pamwe chete nezvimwe zvisina kunangana cannabidiol receptors;
• Post-inoshungurudza kusagadzikana kusagadzikana: chidzidzo chakaitwa nevanhu vakaonekwa kuti vane post-traumatic stress vakaona kuti kushandiswa kwe cannabidiol kwakakonzera kuvandudzwa kwezviratidzo zvekushushikana uye kukanganisika kwekuziva, tichienzanisa neboka rakarapwa ne placebo, umo kuwedzera kwezviratidzo kwaionekwa;
• Kusarara: nekuita mutemo weeuronal uye kuburitsa maurotransmitter, mafuta e cannabidiol anogona kukurudzira kutandara uye, nekudaro, kubatsira pakurapa kwekushaya hope. Izvo zvakaonekwawo mune imwe nyaya yekudzidza kuti iko kushandiswa kwe25 mg yemafuta e cannabidiol akakwanisa kuvandudza hunhu hwekurara;
• Kuzvimba: chidzidzo chakaitwa nemakonzo chakaratidza kuti cannabidiol yaive inoshanda mukugadzirisa maronda ane chekuita nekuzvimba, sezvo ichiita senge inowirirana nema receptors anogarisana nekunzwa kurwadziwa.

Tarisa uone mabhenefiti e cannabidiol mune inotevera vhidhiyo:

Kunyangwe paine zvinoratidza, mashandiro ekuita, zvivakwa uye kusavapo kweTCC kukosheswa, izvo zvinogona kuita kuti oiri ye cannabidiol igamuchirwe munharaunda yekurapa nesainzi, mhedzisiro yekushandisa iyi oiri munguva refu haisati yasimbiswa, uye zvimwe Zvidzidzo zviri inodiwa kubatsira kuratidza mhedzisiro yemafuta eCBD mune vanhu vazhinji.

Muna 2018, iyo Kudya Zvinodhaka Kutonga (FDA) yakabvumidza kushandiswa kwemushonga, Epidiolex, iyo inongowanikwa chete ne cannabidiol pakurapa pfari, zvisinei ANVISA parizvino haisati yazvimisa maererano nekutengesa kwemushonga muBrazil.

Kusvika parizvino, ANVISA yakabvumidza kushambadzira kwaMevatyl, unova mushonga unogadzirwa ne cannabidiol uye THC inoratidzirwa kunyanya kurapa kusazvibata kwemhasuru zvinoitika mu multiple sclerosis uye kushandiswa kwayo kunofanirwa kuratidzwa nachiremba. Ona zvimwe nezve Mevatyl uye zvinoratidza kwayo.

Zvinogona kuitika mhedzisiro

Zvimwe zvidzidzo zvakaona kuti mhedzisiro yemafuta e cannabidiol ane chekuita nekushandisa zvisirizvo kwechigadzirwa, kunyanya pasina kuratidzwa nachiremba kana mukuwedzera kuwanda, nekuneta uye kurara zvakanyanya, manyoka, shanduko mukuda uye uremu, kusagadzikana, manyoka, kurutsa nekufema matambudziko. Uye zvakare, zvakawanikwa kuti madosi muvana ari pamusoro pe200 mg ye cannabidiol inogona kukuvadza zviratidzo zvine chekuita nekushushikana, mukuwedzera mukusimudzira kuwanda kwemoyo nemitupo.

Zvakawanikwa zvakare kuti cannabidiol inogona kukanganisa chiitiko cheiyo enzyme inogadzirwa nechiropa, cytochrome P450, iyo, pakati pemamwe mabasa, inoitisa kudzimwa kwemimwe mishonga nehupfu. Nekudaro, CBD inogona kukanganisa mhedzisiro yemamwe madhiragi, pamwe nekuderedza kugona kwechiropa kuputsa uye kubvisa chepfu, iyo inogona kuwedzera njodzi yechiropa chepfu.

Uye zvakare, kushandiswa kwemafuta e cannabidiol hakuratidzwe kune vakadzi vane nhumbu, vari kuronga kubata nhumbu kana vari kuyamwisa, nekuti zvakawanikwa kuti CBD inogona kuwanikwa mumukaka wemvere, mukuwedzera pakukwanisa kuendeswa kumucheche panguva yepamuviri. .